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Background and objective: Rising incidence of mental health problems is a serious issue all over the world. Adolescents living in orphanages are at a particular risk as they have numerous challenges in their life and coping with them requires adequate life skills. This study aims to assess the emotional and behavioral issues and the coping strategies adopted by adolescent orphans in Pakistan. Methods: This cross-sectional study comprises 109 adolescent orphans living in different orphanages. The Strengths and Difficulties Questionnaire for evaluating the emotional and behavioral problems (EBPs) was used while KIDCOPE scale was adopted to assess the coping strategies. Results: About 34.9% of orphans fell in an abnormal range of EBP and 22.9% were in the borderline zone. The most prevalent problem was conduct (25.7%) followed by peer problems (24.8%), emotional instability (18.3%), hyperactivity (17.4%), and prosocial behavior (11%). A significant and positive correlation was observed between peer problems and maladaptive strategies (r = 0.191, p = 0.047) and between prosocial behavior and adaptive strategies (r = 0.294, p = 0.002). Conclusion: Orphans residing in orphanages suffer from behavioral and emotional problems and are using maladaptive coping strategies. It is highly suggestive to monitor and maintain an optimal psychological health of this vulnerable population in our country. [ABSTRACT FROM AUTHOR]

Nanostructured materials along with an added value of polymers-based support carriers have gained high interest and considered ideal for enzyme immobilization. The recently emerged nanoscience interface in the form of nanostructured materials combined with immobilized-enzyme-based bio-catalysis has now become research and development frontiers in advance and applied bio-catalysis engineering. With the involvement of nanoscience, various polymers have been thoroughly developed and exploited to nanostructured engineer constructs as ideal support carriers/matrices. Such nanotechnologically engineered support carriers/matrix possesses unique structural, physicochemical, and functional attributes which equilibrate principal factors and strengthen the biocatalysts efficacy for multipurpose applications. In addition, nano-supported catalysts are potential alternatives that can outstrip several limitations of conventional biocatalysts, such as reduced catalytic efficacy and turnover, low mass transfer efficiency, instability during the reaction, and most importantly, partial, or complete inhibition/deactivation. In this context, engineering robust and highly efficient biocatalysts is an industrially relevant prerequisite. This review comprehensively covered various biopolymers and nanostructured materials, including silica, hybrid nanoflower, nanotubes or nanofibers, nanomembranes, graphene oxide nanoparticles, metal-oxide frameworks, and magnetic nanoparticles as robust matrices for cellulase immobilization. The work is further enriched by spotlighting applied and industrially relevant considerations of nano-immobilized cellulases. For instance, owing to the cellulose-deconstruction features of nano-immobilized cellulases, the applications like lignocellulosic biomass conversion into industrially useful products or biofuels, improved paper sheet density and pulp beat in paper and pulp industry, fruit juice clarification in food industry are evident examples of cellulases, thereof are discussed in this work. [Display omitted] • Herein, nano-biocatalytic systems are comprehensively discussed with potential applications. • Immobilized-cellulase based bio-catalysis has become research and development frontiers. • Various applied perspectives are given with suitable examples. • Lignocellulosic biomass conversion into industrially useful products or biofuels • Fruit juice clarification in food industry is evident examples and discussed herein. [ABSTRACT FROM AUTHOR]

ABSTRACT Background and Objective: The elderly face various health challenges in later life as their immune defenses deteriorate leaving them quite vulnerable and frail. The situation becomes all the more desperate when the basic health support system is compromised or simply unavailable. This study has been conducted to assess the perceived health status of residents of local old-age homes and their access to available health services. Methods: This cross-sectional study was carried out on 119 elderly subjects living in old age homes (OAHs) in Lahore city of Pakistan. Using the Short Form 36 Health Survey Questionnaire, health-related outcomes of the geriatric population were assessed under eight domains while a self-structured questionnaire was used to determine the level of available health care facilities. Results: The mean age of the study population was 69.88 ± 5.08 years The lowest mean score is observed in the pain domain i.e., 19.20 ± 12.12, whereas a little better score has been seen for emotional well-being i.e., (58.28 ± 26.58). Insufficient health care services have been regarded as a major issue for the elderly face in OAHs. Conclusion: The elderly population living in OAHs suffer from poor health status and face multiple barriers to accessing basic health care facilities. [ABSTRACT FROM AUTHOR]

Population growth and industrialization is associated with the elevation of hazardous pollutants, including heavy metals, biomedical wastes, personal-care products, endocrine-disrupters, pharmaceutically active compounds, and colorants in the environment. The scientific focus has been devoted to developing novel adsorbents to mitigate hazardous pollutants by constructing hybrids of different polymers and nano-structured materials for improved workability and physicochemical attributes. Recently, much attention has been devoted to nanomaterials in environmental remediation, owning to their exceptional characteristics including novel electrical/chemical features, quantum size effects, tunable functionalization, high scalability, and surface-area-to-volume ratio. Target-specific designing of nanocomposites impart high functionality. The cost-effective and eco-friendly synthesis of bioadsorbent materials is increasing for the removal of hazardous pollutants. Due to biocompatible, biodegradable, and eco-friendly nature, sodium alginate has been widely reported for the preparation of bioadsorbent materials to remove different inorganic/organic pollutants. In this review, the potentialities of alginate-based nanocomposites have been described for environmental remediation purposes. Different nanomaterials, including silica, metallic oxide, graphene oxide, hybrid inorganic-organic, non-magnetic-magnetic, carbon nanorods, nanotubes, polymeric nanocarriers, and several other materials have been described in combination with alginate biopolymer for environmental remediation. [Display omitted] • Alginate-based nano-adsorbent materials to remediate pollutants are reviewed. • Recalcitrant pollutants present a serious threat to environmental sustainability. • Various nanohybrids-assisted remediation approaches are given for pollutants. [ABSTRACT FROM AUTHOR]

Fast industrialization and population growth are associated with the increased release of hazardous contaminants in the environment. These hazardous substances, including pharmaceutical, biomedical, personal-care products, heavy metals, endocrine-disrupters, and colorants, pollute the ecosystem by disturbing nature's balance. Nanotechnology has paved new horizons in biochemical engineering by designing novel approaches of integrating nanoscale science with biotechnology to construct improved quality materials for target uptake of pollutants. Recently, nanostructured materials have emerged as research and development frontiers owing to their excellent properties. The tailored designing of nanohybrids constructs with physicochemical alteration enables the nano-bioadsorbent with high target specificity and efficiency. The development of eco-friendly, biodegradable, cost-efficient, and biopolymer-based nanohybrid constructs is gaining attention to remove hazardous environmental pollutants. κ-carrageenan biopolymer is frequently used with different nanomaterials to design nanohybrid bio-adsorbents to remove various contaminants. Herein, the potentialities of carrageenan-based nanohybrid constructs in environmental remediation have been summarized. Different nanostructures, e.g., silica, non-magnetic/magnetic, carbon nanotubes/nanorods, nanoclay/nanomembrane, metal organic frameworks, graphene oxide, and other nanomaterials have been described in combination with carrageenan biopolymers focusing on environmental remediation. [ABSTRACT FROM AUTHOR]

Nanocellulose is a promising "green" nanomaterial that has recently gained scientific interest because of its excellent characteristics, such as less risks of toxicity, biocompatibility, biodegradability, recyclability, and tunable surface features. Initially, three nanocellulose types (i.e., bacterial nanocellulose, nanocrystals, and nanofibers) and their potential biotechnological production routes have been discussed in detail. Contemporary studies are discussed in the development of nanocellulose aerogels, responsive hydrogels, injectable hydrogels/implants, and magnetic nanocellulose. Moreover, the development of hydrogels and potential crosslinking agents for the induction of desired properties has been described. Studies have revealed that the release kinetics of nanocellulosic gels/hydrogels varies from few minutes to several days depending on the given physicochemical conditions. However, such systems provide sustained drug release properties, so they are considered "smart" systems. Recent studies on controlled drug delivery systems have demonstrated their considerable potential for the next-generation transport of therapeutic drugs to target sites via various administration routes. This review presents the selection of appropriate sources and processing methodologies for the development of target nanocellulose types. It explains the potential challenges and opportunities and recommends future research directions about the smart delivery of therapeutic drugs. [Display omitted] [ABSTRACT FROM AUTHOR]