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1. Baisse du recours aux soins et services de santé chez les patients atteints de polyarthriterhumatoïde active sévère à modérée débutant un traitement par le certolizumab pégol en France(étude observationnelle ECLAIR)

2. Maintien à long terme de la réponse chez les patients atteints de polyarthrite rhumatoïde traités par lecertolizumab pégol

3. Reduced T-shaped soil domain for nonlinear dynamic soil-bridge interaction analysis

4. Inflammatory biomarkers and prediction of insulin resistance in Congolese adults

5. Transmission of atypical bovine prions to mice transgenic for human prion protein.

7. Species barrier as molecular basis for adaptation of synthetic prions with N-terminally truncated PrP.

8. Assessment of the Zoonotic Potential of Atypical Scrapie Prions in Humanized Mice Reveals Rare Phenotypic Convergence but Not Identity With Sporadic Creutzfeldt-Jakob Disease Prions.

9. The Smallest Infectious Substructure Encoding the Prion Strain Structural Determinant Revealed by Spontaneous Dissociation of Misfolded Prion Protein Assemblies.

10. Prion potentiation after life-long dormancy in mice devoid of PrP.

11. Improving the Predictive Value of Prion Inactivation Validation Methods to Minimize the Risks of Iatrogenic Transmission With Medical Instruments.

12. Host prion protein expression levels impact prion tropism for the spleen.

13. Crossing Species Barriers Relies on Structurally Distinct Prion Assemblies and Their Complementation.

14. Correlation between Bioassay and Protein Misfolding Cyclic Amplification for Variant Creutzfeldt-Jakob Disease Decontamination Studies.

15. Prion strain-dependent tropism is maintained between spleen and granuloma and relies on lymphofollicular structures.

16. Early stage prion assembly involves two subpopulations with different quaternary structures and a secondary templating pathway.

17. Heterogeneity and Architecture of Pathological Prion Protein Assemblies: Time to Revisit the Molecular Basis of the Prion Replication Process?

18. Epigenetic Control of the Notch and Eph Signaling Pathways by the Prion Protein: Implications for Prion Diseases.

19. Reversible unfolding of infectious prion assemblies reveals the existence of an oligomeric elementary brick.

20. Divergent prion strain evolution driven by PrP C expression level in transgenic mice.

21. A stretch of residues within the protease-resistant core is not necessary for prion structure and infectivity.

22. Absence of Evidence for a Causal Link between Bovine Spongiform Encephalopathy Strain Variant L-BSE and Known Forms of Sporadic Creutzfeldt-Jakob Disease in Human PrP Transgenic Mice.

23. Generating Bona Fide Mammalian Prions with Internal Deletions.

24. Glycoform-independent prion conversion by highly efficient, cell-based, protein misfolding cyclic amplification.

25. Emergence of two prion subtypes in ovine PrP transgenic mice infected with human MM2-cortical Creutzfeldt-Jakob disease prions.

26. Mutated but Not Deleted Ovine PrP(C) N-Terminal Polybasic Region Strongly Interferes with Prion Propagation in Transgenic Mice.

27. Evidence for zoonotic potential of ovine scrapie prions.

28. Accelerated, spleen-based titration of variant Creutzfeldt-Jakob disease infectivity in transgenic mice expressing human prion protein with sensitivity comparable to that of survival time bioassay.

29. Highly infectious prions generated by a single round of microplate-based protein misfolding cyclic amplification.

30. Quaternary structure of pathological prion protein as a determining factor of strain-specific prion replication dynamics.

31. Facilitated cross-species transmission of prions in extraneural tissue.

32. LIPH expression in skin and hair follicles of normal coat and Rex rabbits.

33. Sheep and goat BSE propagate more efficiently than cattle BSE in human PrP transgenic mice.

34. The physical relationship between infectivity and prion protein aggregates is strain-dependent.

35. Prominent and persistent extraneural infection in human PrP transgenic mice infected with variant CJD.

36. A bovine prion acquires an epidemic bovine spongiform encephalopathy strain-like phenotype on interspecies transmission.

37. Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy.

38. Detection of a raft-located estrogen receptor-like protein distinct from ER alpha.

39. A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes.

40. Comparison of clinical and pathological diagnoses in dogs.

41. Conservation of the prion properties of Ure2p through evolution.

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