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A case of acrokeratoelastoidosis (AKE) is reported. A review of the literature has established that at least three clinicopathological entities have been reported under this term. Two of the entities show a combination of hyperkeratosis with fragmentation of dermal elastic tissue, which justifies the designation AKE. The first, for which the term familial AKE is perhaps appropriate, though many cases have been sporadic, begins in childhood or early adult life, and there is no evidence that trauma or light exposure are factors in its production. The second is a more variable clinical syndrome occurring in middle or late adult life, and both physical trauma and light exposure appear to be concerned in its induction. The third syndrome to be reported under the designation AKE shows no abnormality of elastic tissue and appears to be a separate entity. [ABSTRACT FROM AUTHOR]

Reports that the Willan Library in Great Britain has bought rarer works on dermatology. Acquisition of the works of Ernest Bazin; Purchase of a rare copy of the book "Essay by Prosper Baumés, of Lyon." Profile of dermatologist Prosper Baumés.

The article traces the pathological history of keratoacanthoma, a kind of tumor. According to the author, the lesion had long been recognized by surgeons and by dermatologists, and occasional case reports can be found in the proceedings of nineteenth century clinical meetings. However, the diagnostic label, if there was one, attached to such reports was commonly atypical or self-limiting epithelioma. Past researchers have not defined the clinical and histological features, which differentiate the keratoacanthoma from a squamous epithelioma, convincingly.

The article presents information on the state of dermatological setting in Great Britain during the late nineteenth century. During this period, the skin hospitals in various cities of Great Britain provided service to patients and a training ground for future dermatologists. The country entered the eighties with a small group of individuals of very varied training and experience more or less committed to the study and practice of dermatology. Contributions on dermatological topics were not uncommon in the general medical societies and the general journals, but the need for a specialized journal was becoming increasingly urgent as the specialty expanded.

The article reports on the establishment of dermatological hospitals in London, England, in order to meet the rising demands of the ever rising population of London. In response to this urgent need general dispensaries were established in London and in other large cities from 1770 onwards. Such dispensaries were in effect general medical and surgical outpatient clinics, subsidized by private charity. Many provided home visits for patients too ill to come to the dispensary. Some of them attracted medical staff of high caliber. Dermatology as a specialty did not exist, but surgeons in their routine courses often devoted several lectures to diseases of the skin.

Provides information about the Willan Library in the Willan Room of the Royal College of Physicians in London, England. Founder of the library; Collections on British history of dermatology; Instruction for membership.

Presents a case study about pyoderma gangrenosum. Outbreak of septic lesions on the skin of the patients; Development of ulceration on the leg; Clinical features of the disease.

Discusses different aspects of cutaneous androgen-dependent syndromes. Influences of racial and genetic factors on hair pattern and distribution; Significance of hair distribution pattern of facial, scalp and body personal emotions of individuals from different races; Concerns of many new generation Middle Eastern females regarding hirsutism; Changes in hair pattern as components of the androgen-dependent syndrome in female; Discussion on endocrine mechanisms controlling hair pattern.

Aims to understand the relationship between microorganisms and the diseases with which they appeared to be associated. Observations on the use of the microscope in investigations connected with anatomy, physiology and pathology; Attitudes towards host-parasite relationship; Focus on the pioneers of medical mycology. INSET: Dermatology 1904.

Describes several dermatological cases on the development of Thomson's type congenital cutaneous dystrophy. Similarities in clinical features observed in reported cases of the disease; Results of the histological examination of skin lesions of patients; Rationale behind the refusal of other doctors to use the term poikiloderma congenitale to describe Thomson's cases.

The article provides information the history of dermatological journals in Great Britain. The first medical periodicals were published in the seventeenth century and were adaptations of contemporary news-sheets, ephemeral and of limited circulation, designed to serve political or personal rather than scientific ends. The earliest known to have been published in Britain was "Medidna Curiosa," in 1684. The transactions of learned societies and the general medical journals published from their earliest days many papers on dermatology and what are now other specialties. The "Journal of Cutaneous Medicine and Diseases of the Skin, A Quarterly Record of Dermatological Science," was published by John Churchill and Sons, of London. For about 20 years after the failure of the Journal of Cutaneous Medicine there was no journal of dermatology in Britain. The "British Journal of Dermatology," which was in its first decade, came as a specialist periodical of that time.

Disturbances of hair growth and pigmentation induced by chemical agents are more familiar to the veterinary surgeon than to the dermatologist, but are becoming increasingly common in medical practice. The chemicals found to influence hair growth in man are discussed and their possible mode of action is described. The anticoagulant drugs and the anti-mitotic agents prescribed in neoplastic disease account for most cases of chemical alopecia but many other substances are of actual or potential importance. The chemicals inducing changes in hair colour are briefly discussed. Therapeutic agents and accidentally ingested chemicals should be considered in any unexplained disturbance of the growth or colour of the hair. [ABSTRACT FROM AUTHOR]

A case of proved cutaneous cryptococcosis in an Englishman with no evidence of pulmonary or cerebral infection is reported. The abscess healed after incision without further treatment, and the man remains well after five years. The cutaneous manifestations and diagnosis of eryptococcosis are briefly reviewed, and the British cases tabulated. [ABSTRACT FROM AUTHOR]

Three cases of plant dermatitis are reported, in which the patients were shown to react to only one or a limited number of the horticultural varieties they handled. the mechanisms underlying this phenomenon are described and a short account is given of some of the plants concerned. Others likely to manifest this phenomenon are mentioned. The significance of variety-specific dermatitis is discussed and its practical importance for the patient and the dermatologist is emphasized. [ABSTRACT FROM AUTHOR]

The article presents a discussion on autosensitization to skin. It can be defined as a form of autointoxication derived from changes in the patient's own tissues. The term has found fame and fortune in the thought and writings of dermatologists, and is quite regularly applied as a diagnostic label to the sudden dissemination often without obvious provocation of a primarily circumscribed eczema. In this context, the article reflects on certain postulates that should be fulfilled in relation to know more about certain disorders of the skin, and to suggest which disorders may by analogy be considered as possibly dependent on autoimmune mechanisms.

During a two-year period 40 infections with T. discoides and 37 infections with T. mentagrophytes were encountered in the Cambridge area. T. discoides infections were most prevalent in the winter months but T. mentagrophytes infections showed no seasonal incidence. T. discoides infections were usually contracted from cattle; in T. mentagrophytes infections various animal hosts were suspected, but the source was often difficult to trace. Both infections were common in children under puberty ; males were more often affected than females at all ages. T. discoides occurred particularly during the first 20 years of working life and was uncommon over the age of 40 ; the age incidence of T. mentagrophytes infections after puberty was more evenly distributed. There were no significant and constant clinical differences between the two infections. [ABSTRACT FROM AUTHOR]

A clinical study of 54 bullous eruptions classified as pemphigus or pemphigoid according to histological criteria. Pemphigoid is shown to differ from pemphigus in its clinical features, course, prognosis and response to treatment. [ABSTRACT FROM AUTHOR]