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1,324 results on '"Santos, Tiago"'

1. What is Anti-Literature?

Author

Santos, Tiago

Subjects
poesia concreta, política, antropofagia, américa latina, Language and Literature, Literature (General), PN1-6790
Abstract

Recensão crítica de Adam Joseph Shellhorse, Anti-Literature: The Politics and Limits of Representation in Modern Brazil and Argentina, Pittsburg: University of Pittsburg Press, 2017. 258 pp. ISBN 978-0-8229-6447-6.

Published
2019
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2. Intemporal Futura

Author

Santos, Tiago

Subjects
futura, eisele, ludwig, naegele, renner, Language and Literature, Literature (General), PN1-6790
Abstract

Recensão crítica de Petra Eisele, Annette Ludwig e Isabel Naegele. Futura: The Typeface. London: Laurence King Publishing, 2017. 519 pp. ISBN 978-17-8627-093-1.

Published
2019
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7. A Randomized, Open-Label, Non-inferiority Clinical Trial Assessing 7 Versus 14 Days of Antimicrobial Therapy for Severe Multidrug-Resistant Gram-Negative Bacterial Infections: The OPTIMISE Trial Protocol

Author

Arns, Beatriz, Horvath, Jaqueline Driemeyer C., Rech, Gabriela Soares, Sesin, Guilhermo Prates, Agani, Crepin Aziz Jose Oluwafoumi, da Rosa, Bruna Silveira, dos Santos, Tiago Marcon, Brochier, Liliane Spencer Bittencourt, Cavalcanti, Alexandre Biasi, Tomazini, Bruno Martins, Pereira, Adriano Jose, Veiga, Viviane Cordeiro, Nascimento, Giovana Marssola, Kalil, Andre C., and Zavascki, Alexandre P.

Published
2024
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19. Disentangling the veil line for Brazilian biodiversity: An overview from two long-term research programs reveals huge gaps in ecological data reporting

Author

Guimaraes, Aretha Franklin, de Alagao Querido, Luciano Carramaschi, Rocha, Taina, de Jesus Rodrigues, Domingos, Viana, Pedro Lage, de Godoy Bergallo, Helena, Fernandes, Geraldo Wilson, Toma, Tiago Shizen Pacheco, Streit, Helena, Overbeck, Gerhard Ernst, de Souza, Alberico Queiroz Salgueiro, Lima, Albertina Pimentel, da Rosa, Clarissa Alves, de Viveiros Grelle, Carlos Eduardo, Lopes, Alessandra Monteiro, Curcino, Alexandre, de Paula, Alexandre Souza, Andriolo, Aline, dos Santos Dias, Aline, Santos, Aline Tavares, Bernardes, Amanda Araujo, da Silva Oliveira, Amanda Batista, de Barros, Ana Angelica Monteiro, e Silva, Ana Carolina Borges Lins, da Cruz, Ana Carolina Rodrigues, de Holanda, Ana Sofia Sousa, Bueno, Anderson Saldanha, Nunes-Freitas, Andre Felippe, Yves, Andre, da Silva Alencar, Andreia, Scabin, Andressa Barbara, Manzatto, Angelo Gilberto, Lima, Antonio Cesar Silva, Pontes, Antonio Rossano Mendes, Castro, Arlison B., Gomes, Arthur Monteiro, Banhos, Aureo, Rosado, Bruno H.P., dos Santos Batista, Caio Augusto, Siqueira, Carla Costa, Fontana, Carla Suertegaray, da Rocha, Carlos Frederico Duarte, Brocardo, Carlos R., da Costa Doria, Carolina Rodrigues, Castilho, Carolina Volkmer, Pessanha, Caroline, Cordeiro, Cesar A.M.M., Cronemberger, Cecilia, Andretti, Christian Borges, Cornelius, Cintia, Campos, Ciro, Borges-Matos, Clarice, Barros, Claudia Franca, Keller, Claudia, de Oliveira Cavalcante, Claymir, de Sales Dambros, Cristian, da Silva Machado, Davi Nepomuceno, Tassinari, Diego, Villela, Dora Maria, Chiaraniv, Eduardo, de Farias Geisler, Eduardo, Velez-Martin, Eduardo, Carvalho-Junior, Elildo Alves Ribeiro, Drechsler-Santos, Elisandro Ricardo, Lourenco, Elizabete Captivo, Franklin, Elizabeth, Higashikawa, Emilio Manabu, Pezzini, Flavia, de Oliveira Roque, Fabio, Baccaro, Fabricio Beggiato, Becker, Fernando Gertum, Cabeceira, Fernando Goncalvez, do Prado Florencio, Fernando, Barbosa, Flavia Rodrigues, Zuquim, Gabriela, Ferreira, Guilherme Braga, de Vargas, Guilherme Krahl, Mourao, Guilherme, Rousseau, Guillaume Xavier, de Lima, Haroldo Cavalcante, Farias, Hugo Leonardo Sousa, Kaefer, Igor Luis, Ghizoni, Ivo Rohling, da Costa de Noronha, Janaina, de Oliveira, Jaqueline Lopes, Santos, Jhonson Reginaldo Silva, Jarenkow, Joao Andre, de Melo-Junior, Joao Carlos Ferreira, dos Santos, Joao Vitor Chave, de Oliveira, Jocieli, de Souza, Jorge Luiz Pereira, Baumgratz, Jose Fernando Andrade, de Morais, Jose Wellinton, de Melo Silva, Joyce, de Gois Silva, Julia, Wingert, Juliana M., Menger, Juliana, Ferrer, Juliano, Dayrell, Jussara Santos, da Silva-Goncalves, Kelly Cristina, Torralvo, Kelly, da Silva Cruz, Kely, da Silva Sylvestre, Lana, de Andrade Ribas, Leonor, Battirola, Leandro Dênis, Ramos, Leticia, Caires, Leticia Rocha, da Silva Carvalho, Lidiany Camila, Stegmann, Lis Fernandes, Carvalho, Lucelia Nobre, da Silva Menezes, Luciana, Costa, Luciana Moraes, Podgaiski, Luciana Regina, Silveira, Luis Fabio, Malabarba, Luiz Roberto, Frangipani, Marcelo Araujo, Tabarelli, Marcelo, Nascimento, Marcelo Trindade, Marques, Marcia Cristina Mendes, Spies, Marcia R., de Oliveira dos Santos, Marco Antonio, Anaicy, Marcos, Vital, Marcos Jose Salgado, Silveira, Marcos, Vieira, Marcus Vinicius, de Moura Araujo, Maria Aparecida, de Almeida Silveira, Maria Aurea Pinheiro, Barros, Maria Fabiola, Faitanin, Mariana Alves, Iguatemy, Mariana, da Cunha, Mariana Souza, da Silva Murakami, Mariana Moreira, Messias, Mariluce Rezende, Martins, Marlucia Bonifacio, Camana, Mateus, de Medeiros Correa, Nadjara, Fonseca, Nathan Castro, Prieto-Benavides, Oscar Oswaldo, Pena Rodrigues, Pablo J.F., de Andrade, Paloma Leal, Pequeno, Pedro Aurelio Costa Lima, Gananca, Pedro Henrique Salomao, da Silva Ferreira, Pedro Paulo, de Andrade, Poliana Cristina Rodrigues, Azarak, Priscila Alencar, de Fraga, Rafael, Rabelo, Rafael M., de Lima Santos, Raylanne, Barbosa, Reinaldo Imbrozio, Dala-Corte, Renato Bolson, Vicente, Ricardo Eduardo, de Oliveira Perdiz, Ricardo, da Cunha Araujo, Rodrigo Paulo, de Andrade, Ricardo Teixeira Gregorio, de Cassia Quitete Portela, Rita, Fadini, Rodrigo, Feitosa, Rodrigo Machado, Santa-Brigida, Rosangela, Cerqueira, Rui, Muller, Sandra Cristina, Santorelli, Sergio, dos Santos, Sonia Barbosa, Cechin, Sonia Zanini, Avilla, Stefano Spiteri, Pansini, Susamar, Aragon, Susan, da Silva Figueiredo, Taina, Sobroza, Tainara Venturini, de Fatima Ramos Guimaraes, Tais, dos Santos, Talitha Ferreira, Emilio, Thaise, de Azevedo Amorim, Thiago, Izzo, Thiago, Sogral, Thadeu, dos Santos, Tiago Gomes, Vincent, Timothy Lee, de Lima Rocha, Tomas, Pillar, Valerio D., Mesquita, Vanessa Pontes, Silva, Vinicius Duncan, Cyrino, Vitor Melo Erse, Borges-Junior, Vitor Nelson Teixeira, Layme, Viviane Maria Guedes, Mota, Wendarlem Galvao, Santos, Wenderson Nunes, Drose, William, Silva, Williamar Rodrigues, and Magnusson, William E.

Published
2024
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25. Genetically modified ZIKA virus as a microRNA-sensitive oncolytic virus against central nervous system tumors

Author

Novaes, Gabriela Machado, Lima, Caroline, Longo, Carla, Machado, Pedro Henrique, Silva, Thais Peron, Olberg, Giovanna Gonçalves de Oliveira, Módolo, Diego Grando, Pereira, Márcia Cristina Leite, Santos, Tiago Goss, Zatz, Mayana, Lagares, David, de Franco, Marcelo, Ho, Paulo Lee, Bulstrode, Harry, Okamoto, Oswaldo Keith, and Kaid, Carolini

Published
2024
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30. Maturity-onset diabetes of the young in a large Portuguese cohort

Author

Santos Monteiro, Sílvia, da Silva Santos, Tiago, Fonseca, Liliana, Assunção, Guilherme, Lopes, Ana M., Duarte, Diana B., Soares, Ana Rita, Laranjeira, Francisco, Ribeiro, Isaura, Pinto, Eugénia, Rocha, Sónia, Barbosa Gouveia, Sofia, Vazquez-Mosquera, María Eugenia, Oliveira, Maria João, Borges, Teresa, and Cardoso, Maria Helena

Published
2023
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33. Characterization of inducible antibiotic production by streptomycetes isolated from hyper-arid environments

Author

Santos, Tiago Melo, Edrada-Ebel, RuAngelie, and Herron, Paul

Subjects
615.3
Abstract

Antimicrobial resistance is a major threat to the future of human society with 10 million deaths projected in 2050. However, the search for new antimicrobials faces a setback in the rediscovery of the already known antibiotics. One strategy to mitigate this problem is the study of isolates from extreme environments, e.g. the Atacama Desert in Chile, adapted to those conditions and potentially encoding new specialised metabolites. Another method is to employ a multi-approach strategy for the discovery and elucidation of new metabolites combining genomics and metabolomics. This research project employed bioactivity assays, whole-genome analysis and metabolomics to determine the antibiotic potential from bioassays, identification of potential biosynthetic gene clusters and the elucidation of the compounds(s) responsible for the activity. Fourteen strains, closely related to Streptomyces phaeoluteigriseus by 16S rRNA, were isolated from two locations 30 km apart with similar altitude from the Atacama Desert. Further to taxonomic similarity the isolates showed also observable similarities, e.g. soluble pigment, despite inhabiting different locations. However, differential growth inhibition of several indicator strains, e.g. Staphylococcus aureus and Enterococcus faecalis was observed between isolates of both locations. Furthermore, phenotypic analysis and hyper-spectral imaging revealed hidden diversity of the isolates. Whole-genome analysis contradicted the phylogenetic relationship observed using 16S rRNA. Unique inter and intraspecific variations between isolates emerged with two distinct clades forming, revealing the possibility of soil 7 isolates to be a new species. Additionally, highly diverse plasmid profiles were observed instead of phages suggesting that the observed unique variations could result from horizontal gene transfer. Antibacterial activity was observed in solid and liquid cultures, especially in isolates from soil 7. Mass spectrometry analysis helped identify cinerubin B and unknown congeners of actinomycin (MW 1307.552). The latter were produced in large quantity by PH2 8 and further scale-up fermentation allowed the purification of an anti-E. faecalis metabolite. Actinomycin Y1 was its main constituent however further purification is required due to its low purity. In this study, the potential of the Atacama Desert to promote genetic and metabolomic diversification of closely evolutionary strains by niche specific pressures leading to production of known and, most importantly, bioactive metabolite production was demonstrated.

Published
2020
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