241 results on '"Schäfer, Reinhold"'
Search Results
2. Silencing effects of mutant RAS signalling on transcriptomes
3. Identification of a neural development gene expression signature in colon cancer stem cells reveals a role for EGR2 in tumorigenesis
4. RNA sequencing of long-term label-retaining colon cancer stem cells identifies novel regulators of quiescence
5. A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer
6. Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe
7. VIST - a Variant-Information Search Tool for precision oncology
8. The FGFR inhibitor PD173074 binds to the C‐terminus of oncofetal HMGA2 and modulates its DNA‐binding and transcriptional activation functions.
9. Guidelines for the selection of functional assays to evaluate the hallmarks of cancer
10. Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures
11. Growth-Inhibitory Activity and Downregulation of the Class II Tumor-Suppressor Gene H-rev107 in Tumor Cell Lines and Experimental Tumors
12. A primary undifferentiated pleomorphic sarcoma of the lumbosacral region harboring a LMNA-NTRK1 gene fusion with durable clinical response to crizotinib: a case report
13. Editorial: Hallmark of cancer: Evasion of growth suppressors.
14. Expression of the Murine Small Heat Shock Proteins hsp 25 and αB Crystallin in the Absence of Stress
15. Partial Reversion of the Transformed Phenotype in HRAS-Transfected Tumorigenic Cells by Transfer of a Human Gene
16. Molecular and Functional Analysis of Tumor-Suppressor Genes by Transfection
17. IC50: an unsuitable measure for large-sized prostate cancer spheroids in drug sensitivity evaluation.
18. RecurrenceOnline: an online analysis tool to determine breast cancer recurrence and hormone receptor status using microarray data
19. Meta-analysis of gene expression profiles related to relapse-free survival in 1,079 breast cancer patients
20. Chapter 7 - The human transcriptome: implications for understanding, diagnosing, and treating human disease
21. Systems pathology—or how to solve the complex problem of predictive pathology
22. Evaluation of JQ1 Combined With Docetaxel for the Treatment of Prostate Cancer Cells in 2D- and 3D-Culture Systems.
23. Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer
24. Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival
25. Transcriptional basis of KRAS oncogene-mediated cellular transformation in ovarian epithelial cells
26. The class II tumour suppressor gene H-REV107-1 is a target of interferon-regulatory factor-1 and is involved in IFNγ-induced cell death in human ovarian carcinoma cells
27. Gene expression profiling of fibroblasts resistant toward oncogene-mediated transformation reveals preferential transcription of negative growth regulators
28. Transcriptional and translational downregulation of H-REV107, a class II tumour suppressor gene located on human chromosome 11q11-12
29. Systematic evaluation of the miRNA-ome and its downstream effects on mRNA expression identifies gastric cancer progression
30. Prognostic significance of Dicer expression in ovarian cancer—link to global microRNA changes and oestrogen receptor expression
31. Down-regulation of HLA Class I and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells
32. A systems biological approach suggests that transcriptional feedback regulation by dual-specificity phosphatase 6 shapes extracellular signal-related kinase activity in RAS-transformed fibroblasts
33. Discovery and Validation of Novel Biomarkers for Detection of Epithelial Ovarian Cancer
34. Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations
35. Suppression of the TIG3 tumor suppressor gene in human ovarian carcinomas is mediated via mitogen-activated kinase-dependent and -independent mechanisms
36. HuSiDa—the human siRNA database: an open-access database for published functional siRNA sequences and technical details of efficient transfer into recipient cells
37. The PDZ-LIM protein RIL modulates actin stress fiber turnover and enhances the association of α-actinin with F-actin
38. Chapter 7 - The Human Transcriptome: Implications for Understanding, Diagnosing, and Treating Human Disease
39. Nitric oxide mediates apoptosis induction selectively in transformed fibroblasts compared to nontransformed fibroblasts
40. ras oncogene expression determines sensitivity for intercellular induction of apoptosis
41. Characterization of AKT independent effects of the synthetic AKT inhibitors SH-5 and SH-6 using an integrated approach combining transcriptomic profiling and signaling pathway perturbations
42. Spectro ML-A Markup Language for Molecular Spectrometry Data
43. Systems pathology—or how to solve the complex problem of predictive pathology
44. List of contributors
45. Comparative Analysis of Public Knowledge Bases for Precision Oncology.
46. Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures.
47. Tumor mutational burden as a predictive biomarker for molecularly matched therapy in two independent pan-cancer cohorts.
48. Biological activities of wild-type and mutatedP53 genes
49. Expression of H-rev107, a putative tumor suppressor gene, in transformed cell lines and experimental tumors
50. Suppression of the neoplastic phenotype and “anti-oncogenes”
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