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A retrospective study was performed on 342 horses with acute diarrhea (equine colitis). Clinical and laboratory data were obtained upon arrival at the equine hospital. The main focus of this study was to find the difference between the clinical and laboratory variables of surviving and deceased acute colitis horses before the beginning of medical treatment, with the aim to provide a better guideline for determining the prognosis of survival. According to this retrospective study the lethality rate of acute equine colitis was 41.93 %. The time interval from the onset of acute diarrhea to the horse being taken to the clinic was significantly longer in the case of horses which had not survived. The heart rate, hematocrit, blood pH, blood hydrogen carbonate concentration, base excess and HCT/TPP ratio were shown to be significantly related to the survival of horses with colitis. Thus, the hematocrit, appeared to be the most relevant predictor of the outcome of acute equine colitis. Body temperature, respiration rate, total plasma protein and white blood cell count, did not show any prognostic significance.

A total of 272 methicillin-resistant Staphylococcus aureus (MRSA) from equine infections originating from 17 equine hospitals and 39 veterinary practices in Germany as well as 67 isolates from personnel working at equine clinics were subjected to molecular typing. The majority of isolates from horses was attributed to clonal complex (CC) 398 (82.7%). Within CC398, 66% of isolates belonged to a subpopulation (clade) of CC398, which is associated with equine clinics. MRSA attributed to CC8 (ST254, t009, t036, SCC mec IV; ST8, t064, SCC mec IV) were less frequent (16.5%). Single isolates were attributed to ST1, CC22, ST130, and ST1660. The emergence of MRSA CC22 and ST130 in horses was not reported so far. Nasal MRSA colonization was found in 19.5% of veterinary personnel with occupational exposure to horses. The typing characteristics of these isolates corresponded to isolates from equine infections. Comparing typing characteristics of equine isolates with those of a substantial number of isolates from human infections typed at the German Reference Center for Staphylococci and Enterococci (2006-2014; n = 10864) yielded that the proportion of isolates exhibiting characteristics of MRSA from equine medicine is very low (< 0.5%). As this low proportion was also found among MRSA originating from nasal screenings of human carriers not suffering from a staphylococcal infection (n = 5546) transmission of MRSA from equine clinics to the community seems to be rare so far.