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Copyright of Bautechnik is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Bridge inspection is a time-consuming, expensive, but indispensable task. In this work, a new semiautomatic workflow for a concrete bridge condition assessment system is developed and discussed. The workflow consists of three main parts merged in the new methodology. The elements are the data acquisition with cameras, the automated damage detection and localization using a neural network, and the resulting engineering condition assessment. Furthermore, a CAD model serves as a base for the later calculations for the condition assessment. Camera images are used for both sub-millimeter crack detection using semantic segmentation by an artificial neural network and a crack localization based on a combination of a photogrammetric workflow including structure from motion (SfM) and the projection as imprinted points directly onto the as-planned CAD mesh. Moreover, an approach for crack width derivation is given. The captured crack width, crack position, and the date of detection represent the input values for subsequent crack monitoring. Thereby, this new concept is proposed as an essential step towards a time-efficient and objective life-cycle assessment of reinforced concrete structures. [ABSTRACT FROM AUTHOR]

Copyright of Bautechnik is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The methods employed to document cystoscopic findings in bladder cancer patients lack accuracy and are subject to observer variability. We propose a novel endoimaging system and an online documentation platform to provide post-procedural 3D bladder reconstructions for improved diagnosis, management and follow-up. The RaVeNNA4pi consortium is comprised of five industrial partners, two university hospitals and two technical institutes. These are grouped into hardware, software and clinical partners according to their professional expertise. The envisaged endoimaging system consists of an innovative cystoscope that generates 3D bladder reconstructions allowing users to remotely access a cloud-based centralized database to visualize individualized 3D bladder models from previous cystoscopies archived in DICOM format. Preliminary investigations successfully tracked the endoscope's rotational and translational movements. The structure-from-motion pipeline was tested in a bladder phantom and satisfactorily demonstrated 3D reconstructions of the processing sequence. AI-based semantic image segmentation achieved a 0.67 dice-score-coefficient over all classes. An online-platform allows physicians and patients to digitally visualize endoscopic findings by navigating a 3D bladder model. Our work demonstrates the current developments of a novel endoimaging system equipped with the potential to generate 3D bladder reconstructions from cystoscopy videos and AI-assisted automated detection of bladder tumors. [ABSTRACT FROM AUTHOR]

Developing organisms need to adapt to environmental variations as well as to rapid changes in substrate availability and energy demands imposed by fast-growing tissues and organs. Little is known about the adjustments that kidneys undergo in response to these challenges. We performed single-cell RNA sequencing of zebrafish pronephric duct cells to understand how the developing kidney responds to changes in filtered substrates and intrinsic energy requirements. We found high levels of glucose transporters early in development and increased expression of monocarboxylate transporters at later times. This indicates that the zebrafish embryonic kidney displays a high glucose transporting capacity during early development, which is replaced by the ability to absorb monocarboxylates and amino acids at later stages. This change in transport capacity was accompanied by the upregulation of mitochondrial carriers, indicating a switch to increased oxidative phosphorylation to meet the increasing energy demand of a developing kidney. [ABSTRACT FROM AUTHOR]

In this paper we present a modern version of the classic theory of “ultimate psychological hedonism” (UPH). As does the UPH, our two-dimensional model of metatelic orientations also postulates a fundamentally hedonistic motivation for any human action. However, it makes a distinction between “telic” or content-based goals of actions and “metatelic” or emotional reasons for actions. In our view, only the emotional reasons for action, but not the goals of action, conform to the UPH. After outlining our model, we will elucidate the similarities and differences between our model and classic UPH. In this context we will clarify several basic misconceptions regarding classic UPH. In a next step, two major criticisms of the theory of ultimate psychological hedonism will be discussed, that is (1) the statement that the hedonistic principle has no motivating effect at all and (2) the argument that the hedonistic motivation is only one of many motivations of human actions. We believe that both of these arguments can be refuted. Finally, we will discuss the compatibility of our model with evolutionary theory. [ABSTRACT FROM AUTHOR]

Examines the provisions of the German Constitution which limit the liberal concept of toleration. Provisions of the Constitution on basic rights and on the principles of the German political system; Discussion of the limitation of liberal toleration; Evaluation of the provisions on the prohibition of parties and the suspension of individual rights.