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5. Von Willebrand Factor Antigen Improves Risk Stratification for Patients with a Diagnosis of Resectable Hepatocellular Carcinoma

Author

Pereyra, David, Mandorfer, Mattias, Santol, Jonas, Gregory, Lindsey, Koeditz, Christoph, Ortmayr, Gregor, Schuetz, Clara, Rumpf, Benedikt, Ammon, Daphni, Laengle, Johannes, Schwarz, Christoph, Jonas, Jan Philipp, Pinter, Matthias, Lindenlaub, Florian, Tamandl, Dietmar, Thiels, Cornelius, Warner, Susanne, Smoot, Rory, Truty, Mark, Kendrick, Michael, Nagorney, David, Cleary, Sean, Gruenberger, Thomas, Reiberger, Thomas, and Starlinger, Patrick

Published
2024
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9. Correction: A recommendation for the use of electrical biosensing technology in neonatology

Author

van Wyk, Lizelle, Austin, Topun, Barzilay, Bernard, Bravo, Maria Carmen, Breindahl, Morten, Czernik, Christoph, Dempsey, Eugene, de Boode, Willem-Pieter, de Vries, Willem, Eriksen, Beate Horsberg, Fauchére, Jean-Claude, Kooi, Elisabeth M. W., Levy, Philip T., McNamara, Patrick J., Mitra, Subhabrata, Nestaas, Eirik, Rabe, Heike, Rabi, Yacov, Rogerson, Sheryle R., Savoia, Marilena, Schena, Frederico, Sehgal, Arvind, Schwarz, Christoph E., Thome, Ulrich, van Laere, David, Zaharie, Gabriela C., and Gupta, Samir

Published
2024
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11. Reference Ranges for Arterial Oxygen Saturation, Heart Rate, and Cerebral Oxygen Saturation during Immediate Postnatal Transition in Neonates Born Extremely or Very Preterm

Author

Baik-Schneditz, Nariae, Bruckner, Marlies, Binder-Heschl, Corinna, Schlatzer, Christoph, Martensen, Johann, Höller, Nina, Ziehenberger, Evelyn, Mileder, Lukas, Berger, Angelika, Baumgartner, Sigrid, Grill, Agnes, Mayr, Michaela, Rittenschober-Boehm, Judith, Schneider, Michael, Schreiner, Christina, Griesmaier, Elke, Neubauer, Vera, Wöckinger, Peter, Posod, Anna, Marolt, Anja, Dimnik, Ana, Lubej Kurtovič, Vlasta, Aisling, Garvey, Panaviene, Jurate, Healy, David, Ahmed, Nahla, Herlihy, Ita, Franz, Axel, Castoldi, Francesca, Cavigioli, Francesco, Kozłowska, Zuzanna, Minta, Marcin, Owsiańska, Zuzanna, Kahtan, Sonia, Neumann- Klimasińska, Natalia, Wróbel, Karolina, Kubiaczyk, Agata, Kosik, Katarzyna, Olek, Katarzyna, Bugiera, Michalina, Porwolik, Julita, Basiukajć, Agnieszka, Czapla, Elzbieta, Łukaszuk, Wojciech, Gryczka, Katarzyna, Naskręcka, Dobrochna, Mazela, Jan, Szymankiewicz-Bręborowicz, Marta, Klotz, Daniel, Baumgartner, Jana, Bembich, Jana, Travan, Laura, Cheung, Po-Yin, Wolfsberger, Christina H., Schwaberger, Bernhard, Urlesberger, Berndt, Avian, Alexander, Goeral, Katharina, Hammerl, Marlene, Perme, Tina, Dempsey, Eugene M., Springer, Laila, Lista, Gianluca, Szczapa, Tomasz, Fuchs, Hans, Karpinski, Lukasz, Bua, Jenny, Law, Brenda, Buchmayer, Julia, Kiechl-Kohlendorfer, Ursula, Kornhauser-Cerar, Lilijana, Schwarz, Christoph E., Gründler, Kerstin, Stucchi, Ilaria, Klebermass-Schrehof, Katrin, Schmölzer, Georg M., and Pichler, Gerhard

Published
2024
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12. Surgical outcomes of gallbladder cancer: the OMEGA retrospective, multicentre, international cohort study

Author

Abe, Tomoyuki, Abu Hilal, Moh'd, Achalandabaso Boira, Maria del Mar, Adham, Mustapha, Adam, Mohamed, Ahmad, Maryam, Al-Sarireh, Bilal, Albiol, Maite, Alhaboob, Nassir, Alseidi, Adnan, Ammar, Houssem, Anand, Akshay, Andersson, Bodil, Antonakis, Pantelis, Araya, Veronica, Ashley, Stanley W., Atanasov, Georgi, Ausania, Fabio, Balestri, Ricardo, Banerjee, Abhirup, Banerjee, Sudeep, Banting, Simon, Barauskas, Giedrius, Bartsch, Fabian, Belli, Andrea, Beretta, Simona, Berrevoet, Frederik, Bhandari, Ramesh Singh, Blanco Fernandez, Gerardo, Bolm, Louisa, Bonal, Mathieu, Bozkurt, Emre, Braat, Andries E., Bradshaw, Luke, Bramis, Konstantinos, Branes, Alejandro, Burdine, Lyle, Byrne, Matthew, Caceres, Maria, Castro Santiago, Maria Jesus, Chan, Benjamin, Chong, Lynn, Çoker, Ahmet, Conde Rodriguez, Maria, Croagh, Daniel, Crutchley, Alyn, Cutolo, Carmen, D'Hondt, Mathieu, D'Souza, Daniel, Daams, Freek, Dalla Valle, Raffaele, Davide, José, de Bellis, Mario, de Boer, Marieke, de Meyere, Celine, de Reuver, Philip, Dixon, Matthew, Dorovinis, Panagiotis, Echeverría Bauer, Gabriela, Eduarda, Maria, Eker, Hasan, Erdmann, Joris, Erkan, Mert, Felekouras, Evangelos, Felli, Emanuele, Fernandes, Eduardo, Figueroa Rivera, Eduardo, Fulop, Andras, Galun, Daniel, Gerhards, Michael, Ghorbani, Poya, Giannone, Fabio, Gil, Luis, Giorgakis, Emmanouil, Giuffrida, Mario, Giuliante, Felice, Gkekas, Ioannis, Gomez Bravo, Miguel, Groot Koerkamp, Bas, Guevara, Oscar, Guglielmi, Alfredo, Gulla, Aiste, Gupta, Rahul, Gupta, Amit, Gutiérrez, Marta, Hafeez Bhatti, Abu Bakar, Hagendoorn, Jeroen, Hajee, Zain, Hakeem, Abdul Rahman, Hamid, Hytham, Hassen, Sayed, Heinrich, Stefan, Higuchi, Ryota, Hoffman, Daniel, Holroyd, David, Hughes, Daniel, Ivanecz, Arpad, Iype, Satheesh, Jaen Torrejimeno, Isabel, Joglekar, Shantanu, Jones, Robert, Kaczirek, Klaus, Kanhere, Harsh, Kausar, Ambareen, Kee, Zhanyi, Keilson, Jessica, Kleef, Jorg, Klose, Johannes, Knowles, Brett, Koong, Jun Kit, Kumar, Nagappan, Kunnuru, Supreeth, Lakhey, Paleswan Joshi, Laurenzi, Andrea, Lee, Yeong Sing, Leon, Felipe, Leow, Voon Meng, Lequeu, Jean-Baptiste, Lesurtel, Mickael, Lo, Elisabeth, Löb, Stefan, Lockie, Elizabeth, Lodge, Peter, López Garnica, Dolores, Lopez Lopez, Victor, Lundgren, Linda, Machairas, Nikolaos, Maharjan, Dhiresh, Malde, Deep, Martel, Guillaume, Martin, Julie, Mazzola, Michele, Mehrabi, Arianeb, Memeo, Ricardo, Milana, Flavio, Molina, George, Monette, Leah, Morgul, Haluk, Moris, Dimitrios, Morsi-Yeroyannis, Antonios, Mowbray, Nicholas, Mulita, Francesk, Muttillo, Edoardo Maria, Nandasena, Malith, Nashidengo, Pueya Rashid, Nickkholgh, Arash, Noel, Colin Byron, Ohtsuka, Masayuki, Ozolins, Arturs, Pandanaboyana, Sanjay, Pararas, Nikolaos, Parente, Alessandro, Peng, June, Perfecto Valero, Arkaitz, Perinel, Julie, Perivoliotis, Konstatinos, Perra, Teresa, Pessaux, Patrick, Petruch, Natalie, Piccolo, Gaetano, Piros, Laszlo, Porcu, Alberto, Prabakaran, Viswakumar, Prasad, Raj, Prieto Calvo, Mikel, Primavesi, Florian, Pueyo Periz, Eva Maria, Quaglia, Alberto, Ramia Angel, Jose M., Rammohan, Ashwin, Razionale, Francesco, Robles Campos, Ricardo, Roy, Manas, Rozwadowski, Sophie, Ruffolo, Luis, Ruiz, Natalia, Ruzzenante, Andrea, Saadat, Lily, Said, Mohamed Amine, Saladino, Edoardo, Saliba, Gabriel, Sandstrom, Per, Schena, Carlo Alberto, Scholer, Anthony, Schwarz, Christoph, Serafini, Lorenzo, Serrano, Pablo E., Sharma, Deepak, Sheen, Aali, Siddagangaiah, Vishwanath, Silva, Michael, Singh, Saurabh, Siriwardena, Ajith, Skalski, Michal, Smig, Mante, Soliman, Faris, Sonkar, Abhinav Arun, Sousa Silva, Donzília, Sparrelid, Ernesto, Srinivasan, Parthi, Sternby Eilard, Malin, Strobel, Oliver, Stupan, Urban, Suarez-Munoz, Miguel Angel, Subramaniam, Manisekar, Sugiura, Teiichi, Sutcliffe, Robert, Swank, Hilko, Taylor, Lillian, Thapa, Prabin Bikram, The, Catherine, Thepbunchonchai, Asara, Thieu, Caman, Tiwari, Navneet, Torzilli, Guido, Tovikkai, Chutwichai, Trotovsek, Blaz, Tsaramanidis, Savvas, Tsoulfas, Georgios, Uesaka, Katsuhiko, Umar, Garzali, Urbani, Lucio, Vailas, Michail, van Dam, Ronald, van de Boezem, Peter, van Laarhoven, Stijn, Vanagas, Tomas, Van Dooren, Mike, Viennet, Manon, Vigano, Luca, Vijayashanker, Aarathi, Villodre, Celia, Wakai, Toshifumi, Workneh, Aklile, Xu, Li, Yamamoto, Masakazu, Yang, Zhiying, Young, Robert, Zivanovic, Marko, Balakrishnan, Anita, Barmpounakis, Petros, Demiris, Nikolaos, Jah, Asif, Spiers, Harry V.M., Talukder, Shibojit, Martin, Jack L., Gibbs, Paul, Harper, Simon J.F., Huguet, Emmanuel L., Kosmoliaptsis, Vasilis, Liau, Siong S., Praseedom, Raaj K., Basu, Bristi, de Aretxabala, Xavier, Lendoire, Javier, Maithel, Shishir, Serrablo, Alejandro, and Adsay, Volkan

Published
2023
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14. Facial growth dynamics dictate optimal facemask fitting during the first year of life.

Author

Haase, Bianca, Badinska, Ana‐Maria, Sowula, Julian, Springer, Laila, Schwarz, Christoph E., Stauch, Anette, Weismann, Christina, Poets, Christian F., and Wiechers, Cornelia

Subjects
THREE-dimensional imaging, INFANTS, VENTILATION, LONGITUDINAL method, SUBGROUP analysis (Experimental design)
Abstract

Aim: The aim of this study is to prevent mask leak during ventilation in infant emergencies, appropriate facemask fitting is essential. Therefore, we investigated facial profiles during the first year of life and their correlation with the correct sizing of masks. Methods: This is a post hoc subgroup analysis of 32 healthy term infants, based on a prospective observational study performed from September 2018 to December 2019 in Tuebingen, Germany. In 3‐monthly intervals, facial aspects were measured based on anatomical landmarks in three‐dimensional frontal photographs to describe their changes across the first year of life. All infants were awake and breathing spontaneously; none required any anaesthesia. Results: In 130 3D images, mean distance between nasion and gnathion was 54 mm (3.3) measured at birth and 70 mm (3.5) at age 12 months. Gompertz models showed relevant growth‐related changes in the facial profile in vertical but not horizontal direction. Vertical growth occurred mainly in the first 6 months. Boys and girls differed by an average of about 2 mm (boys >girls). Conclusion: Based on our findings, it should now be verified whether the 50 mm facemasks are suitable for infants from birth to 2 months of age, respectively, the 60 mm version for infants aged three to 12 months. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Allograft and patient survival after sequential HSCT and kidney transplantation from the same donor—A multicenter analysis

Author

Eder, Michael, Schwarz, Christoph, Kammer, Michael, Jacobsen, Niels, Stavroula, Masouridi Levrat, Cowan, Morton J., Chongkrairatanakul, Tepsiri, Gaston, Robert, Ravanan, Rommel, Ishida, Hideki, Bachmann, Anette, Alvarez, Sergio, Koch, Martina, Garrouste, Cyril, Duffner, Ulrich A., Cullis, Brett, Schaap, Nicolaas, Medinger, Michael, Sørensen, Søren Schwartz, Dauber, Eva-Maria, Böhmig, Georg, Regele, Heinz, Berlakovich, Gabriela A., Wekerle, Thomas, and Oberbauer, Rainer

Published
2019
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27. Allograft rejection is associated with development of functional IgE specific for donor MHC antigens

Author

Farkas, Andreas M., Baranyi, Ulrike, Böhmig, Georg A., Unger, Lukas, Hopf, Stefan, Wahrmann, Markus, Regele, Heinz, Mahr, Benedikt, Schwarz, Christoph, Hock, Karin, Pilat, Nina, Kristo, Ivan, Mraz, Jasmin, Lupinek, Christian, Thalhamer, Josef, Bond, Gregor, Kuessel, Lorenz, Wlodek, Elizabeth, Martin, Jack, Clatworthy, Menna, Pettigrew, Gavin, Valenta, Rudolf, and Wekerle, Thomas

Published
2019
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30. The Nitrogen Content in the Fruiting Body and Mycelium of Pleurotus Ostreatus and Its Utilization as a Medium Component in Thraustochytrid Fermentation.

Author

Schütte, Lina, Hausmann, Katharina, Schwarz, Christoph, Ersoy, Franziska, and Berger, Ralf G.

Subjects
FRUITING bodies (Fungi), PLEUROTUS ostreatus, MYCELIUM, NITROGEN, AMINO group, FREE groups
Abstract

Following the idea of a circular bioeconomy, the use of side streams as substitutes for cultivation media (components) in bioprocesses would mean an enormous economic and ecological advantage. Costly compounds in conventional media for the production of the triterpene squalene in thraustochytrids are the main carbon source and complex nitrogen sources. Among other side streams examined, extracts from the spent mycelium of the basidiomycete Pleurotus ostreatus were best-suited to acting as alternative nitrogen sources in cultivation media for thraustochytrids. The total nitrogen (3.76 ± 0.01 and 4.24 ± 0.04%, respectively) and protein (16.47 ± 0.06 and 18.57 ± 0.18%, respectively) contents of the fruiting body and mycelium were determined. The fungal cells were hydrolyzed and extracted to generate accessible nitrogen sources. Under preferred conditions, the extracts from the fruiting body and mycelium contained 73.63 ± 1.19 and 89.93 ± 7.54 mM of free amino groups, respectively. Cultivations of Schizochytrium sp. S31 on a medium using a mycelium extract as a complex nitrogen source showed decelerated growth but a similar squalene yield (123.79 ± 14.11 mg/L after 216 h) compared to a conventional medium (111.29 ± 19.96 mg/L, although improvable by additional complex nitrogen source). [ABSTRACT FROM AUTHOR]

Published
2024
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34. Nephrolithiasis Associated with Nephrocalcinosis Is Primarily Composed of Carbonate Apatite.

Author

Kiener, Teresa Antonia, Moré, Elena, Franzen, Michael, Cadamuro, Janne, Schwarz, Christoph, Bergmann, Carsten, and Salmhofer, Hermann

Subjects
KIDNEY stones, KIDNEY calcification, RENAL tubular transport disorders, APATITE, KIDNEY failure, KIDNEY physiology
Abstract

Introduction: This study was designed to determine the mineral composition of calculi in nephrocalcinosis with nephrolithiasis, diagnose the underlying disease, and monitor the course of renal function in patients with nephrocalcinosis-nephrolithiasis. Methods: Renal calculi extruded in a series of 8 patients with nephrocalcinosis were analysed using Fourier transmission infrared spectrometry. In 4 patients, next-generation sequencing using a nephrocalcinosis-nephrolithiasis panel was performed to determine the nature of the underlying disease. In addition, longitudinal analysis of renal function was performed in all patients. Results: Seven patients revealed carbonate apatite as the sole constituent of renal calculi. One patient showed a mixed composition of dicalcium phosphate dihydrate/carbonate apatite at first analysis yet in subsequent episodes also had calculi composed of pure carbonate apatite. Further molecular analysis displayed distal renal tubular acidosis in 2 of 4 patients who consented to sequencing. No known genetic defect could be found in the other two cases. In line with prior reports, decline of renal function was dependent on underlying disease. Distal renal tubular acidosis revealed a progressive course of renal failure, whereas other causes showed stable renal function in long term analysis. Conclusion: Nephrocalcinosis with nephrolithiasis is a rare condition with heterogeneous aetiology. Yet mineral composition of renal calculi predominantly consisted of pure carbonate apatite. This uniform finding is similar to subcutaneous calcifications of various origins and might propose a general principle of tissue calcification. Progressive decline of renal function was found in distal renal tubular acidosis, whereas other conditions remained stable over time. Plain Language Summary: Renal stones may occur in conditions that involve calcification of the kidney itself. In this case series, we chemically analysed these stones. In some cases, we also performed genetic tests. Interestingly, we found a similar composition in most stones, irrespective of the underlying disorder. This suggests a common mechanism of calcification. [ABSTRACT FROM AUTHOR]

Published
2024
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35. Total Antioxidant Capacity of Saliva and Its Correlation with pH Levels among Dental Students under Different Stressful Conditions.

Author

Schwarz, Christoph, Balean, Octavia, Dumitrescu, Ramona, Ciordas, Paula Diana, Marian, Catalin, Georgescu, Marius, Bolchis, Vanessa, Sava-Rosianu, Ruxandra, Fratila, Aurora Doris, Alexa, Iulia, Jumanca, Daniela, and Galuscan, Atena

Subjects
*OXIDANT status, *DENTAL students, *PEARSON correlation (Statistics), *SALIVA, *PSYCHOLOGICAL stress, *DENTAL schools
Abstract

(1) Background: This cross-sectional study conducted at the Faculty of Dental Medicine, Timisoara, Romania, between December 2022 and February 2023 aims to assess salivary total antioxidant capacity and pH levels in dental students experiencing non-stressful and stressful situations and explore potential correlations between these factors. (2) Methods: Saliva samples were collected during two different periods: before an Oral Health course and before the Oral Health exam, under stressful conditions. Ethical principles were followed, and informed consent was obtained. Data on age, gender, health status, drug use, smoking habits, and anxiety levels were recorded. Saliva was collected using the draining method and pH was measured using indicator paper strips. Total antioxidant capacity (TAC) was determined using a commercial assay kit. Statistical analysis involved descriptive statistics, Student's t-test to compare pH and TAC between study groups, and Pearson's correlation coefficient to analyze the correlation between salivary pH and TAC within each group, with p < 0.05 indicating significance. (3) Results: This study involved 80 participants, comprising 26 males and 54 females, all enrolled in the 5th year of the Oral Health course, with ages ranging from 20 to 53 and a mean age of 23.62 (±4.19) years. Pearson's correlation results show a statistically significant negative relationship between the STAI test and TAC during the stress-free period (−0.02 **, N = 80, p < 0.01). (4) Conclusions: There are variations in saliva's antioxidant capacity in response to different stress conditions. Dental students experienced a higher level of stress before academic assessments compared to the non-stress period during the course. [ABSTRACT FROM AUTHOR]

Published
2023
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39. Early initiation of antibiotic therapy and short-term outcomes in preterm infants: a single-centre retrospective cohort analysis.

Author

Köstlin-Gille, Natascha, Serna-Higuita, Lina Maria, Bubser, Caren, Arand, Joerg, Haag, Laura, Schwarz, Christoph E., Heideking, Martin, Poets, Christian F., and Gille, Christian

Subjects
PREMATURE rupture of fetal membranes, APGAR score, NEONATAL sepsis, PREMATURE infants, COHORT analysis, LOW birth weight, VERY low birth weight, ANTIBIOTICS
Published
2023
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43. Link between Oral Health, Periodontal Disease, Smoking, and Systemic Diseases in Romanian Patients.

Author

Schwarz, Christoph, Hajdu, Adrian Ioan, Dumitrescu, Ramona, Sava-Rosianu, Ruxandra, Bolchis, Vanessa, Anusca, Diana, Hanghicel, Andreea, Fratila, Aurora Doris, Oancea, Roxana, Jumanca, Daniela, Galuscan, Atena, and Leretter, Marius

Subjects
RISK factors of periodontal disease, STATISTICS, RESEARCH, ORAL health, CHRONIC diseases, ONE-way analysis of variance, PERIODONTITIS, CROSS-sectional method, RISK assessment, COMPARATIVE studies, SEVERITY of illness index, QUESTIONNAIRES, CHI-squared test, DESCRIPTIVE statistics, QUALITY of life, SMOKING, DATA analysis, DATA analysis software, STATISTICAL correlation, COMORBIDITY
Abstract

(1) Background: The link between oral and systemic health is becoming increasingly obvious. Oral diseases, particularly periodontitis, have been linked to various diseases including diabetes and cardiovascular disease, among others. This survey aimed to assess the oral health condition of individuals, considering both their overall health and periodontal status, by performing oral examinations and collecting data using questionnaires. (2) Methods: After obtaining approval from the University's Ethics Committee, the study was carried out from 2021 to 2022 at the Department of Oral Health, located in the Emergency Municipal Hospital in Timisoara, Timis County, Romania. Bivariate correlations were performed using nonparametric Spearman's Rho using SPPS software version 23. To assess the importance of smoking frequency related to the severity of periodontitis diagnosis, the ANOVA Simple test (one-way) and Hochberg GT2 post hoc analysis were utilized. The chi-squared test was employed for nominal variables. A significance level of 0.05 (alpha = 0.05) was adopted for all statistical tests. (3) Results: There is a significant positive association between the frequency of systemic disease and the severity of the periodontitis diagnosis taken as a total, Rho (242) = 0.151, p < 0.05, and taken as a stage, Rho (242) = 0.199, p < 0.01, thus as the severity of the diagnosis increases, the patient presents comorbidities. Hochberg GT2 post hoc analysis indicates that the non-smoking group has statistically significantly lower diagnostic severity (Mdif = −0.81, p = 0.01), with a strong effect size (Cohen's d = 0.73). (4) Conclusions: The findings are increasingly indicating a potential association between oral diseases and a range of systemic diseases. The impact of periodontal disease on the quality of life is significant, especially in individuals with associated systemic conditions and present risk factors. [ABSTRACT FROM AUTHOR]

Published
2023
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48. Intravenous iron-induced hypophosphatemia and kidney stone disease

Author

Panzer, Marlene, Meindl, Eva, Schaefer, Benedikt, Wagner, Sonja, Glodny, Bernhard, Mayer, Gert, Pircher, Andreas, Schwarz, Christoph, Beckmann, Felix, Hejny, Clivia, Joachim-Mrosko, Bastian, Konzett, Juergen, Tilg, Herbert, Heidegger, Isabel, Wolf, Myles, Weiskirchen, Ralf, and Zoller, Heinz

Published
2024
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