170 results on '"Sloop, Kyle W."'
Search Results
2. The incretin co-agonist tirzepatide requires GIPR for hormone secretion from human islets
3. Tirzepatide induces a thermogenic-like amino acid signature in brown adipose tissue
4. Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets
5. Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist
6. Structural insights into probe-dependent positive allosterism of the GLP-1 receptor
7. Activation of the GLP-1 receptor by a non-peptidic agonist
8. LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept
9. GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice.
10. GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese mice
11. Orforglipron (LY3502970), a novel, oral non‐peptide glucagon‐like peptide‐1 receptor agonist: A Phase 1a, blinded, placebo‐controlled, randomized, single‐ and multiple‐ascending‐dose study in healthy participants.
12. Orforglipron (LY3502970), a novel, oral non‐peptide glucagon‐like peptide‐1 receptor agonist: A Phase 1b, multicentre, blinded, placebo‐controlled, randomized, multiple‐ascending‐dose study in people with type 2 diabetes
13. The Furan Fatty Acid Metabolite CMPF Is Elevated in Diabetes and Induces β Cell Dysfunction
14. LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept
15. Model of pediatric pituitary hormone deficiency separates the endocrine and neural functions of the LHX3 transcription factor in vivo
16. Absence of Glucagon and Insulin Action Reveals a Role for the GLP-1 Receptor in Endogenous Glucose Production
17. GIPR Agonism Inhibits PYY-Induced Nausea-Like Behavior.
18. Is Glucagon Receptor Activation the Thermogenic Solution for Treating Obesity?
19. Severe short stature and endogenous growth hormone resistance in twin brothers without growth hormone gene mutations
20. Novel Small Molecule Glucagon-Like Peptide-1 Receptor Agonist Stimulates Insulin Secretion in Rodents and From Human Islets
21. Deficiency of Adiponectin Receptor 2 Reduces Diet-Induced Insulin Resistance but Promotes Type 2 Diabetes
22. Reduction of Hepatic Protein Tyrosine Phosphatase, Receptor, Type A (PTPRα) Expression Using an Antisense Oligonucleotide Improves Hyperglycemia, Steatosis and Plasma Triglycerides in Diabetic Mice: 1901-P
23. Reduction of Hepatic Glucagon Receptor Expression with an Optimized Antisense Oligonucleotide Increased Active GLP-1 Levels in Cynomolgus Monkeys without Pancreatic Alpha Cell Expansion or Hyperplasia: 1399-P
24. Targeted suppression of an amyloidogenic transthyretin with antisense oligonucleotides
25. Reduction of Hepatic and Adipose Tissue Glucocorticoid Receptor Expression With Antisense Oligonucleotides Improves Hyperglycemia and Hyperlipidemia in Diabetic Rodents Without Causing Systemic Glucocorticoid Antagonism
26. Regulation of the Follicle-Stimulating Hormone β Gene by the LHX3 LIM-Homeodomain Transcription Factor
27. GIPR Function in the Central Nervous System: Implications and Novel Perspectives for GIP-Based Therapies in Treating Metabolic Disorders.
28. Hepatic and glucagon-like peptide-1-mediated reversal of diabetes by glucagon receptor antisense oligonucleotide inhibitors
29. Molecular Analysis of LHX3 and PROP-1 in Pituitary Hormone Deficiency Patients with Posterior Pituitary Ectopia*
30. Differential Activation of Pituitary Hormone Genes by Human Lhx3 Isoforms with Distinct DNA Binding Properties
31. The current state of GPCR‐based drug discovery to treat metabolic disease
32. Discovery of an Orally Efficacious Positive Allosteric Modulator of the Glucagon-like Peptide‑1 Receptor.
33. Glucagon blockade restores functional β-cell mass in type 1 diabetic mice and enhances function of human islets.
34. Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist.
35. The Limited Role of Glucagon for Ketogenesis During Fasting or in Response to SGLT2 Inhibition.
36. GLP-1 Receptor in Pancreatic α-Cells Regulates Glucagon Secretion in a Glucose-Dependent Bidirectional Manner.
37. β Cell GLP-1R Signaling Alters α Cell Proglucagon Processing after Vertical Sleeve Gastrectomy in Mice.
38. Mechanisms to Elevate Endogenous GLP-1 Beyond Injectable GLP-1 Analogs and Metabolic Surgery.
39. Physiology and Emerging Biochemistry of the Glucagon-Like Peptide-1 Receptor
40. Small Molecule Drug Discovery at the Glucagon-Like Peptide-1 Receptor
41. Synthesis and Characterization of Urofuranoic Acids: In Vivo Metabolism of 2-(2-Carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic Acid (CMPF) and Effects on in Vitro Insulin Secretion.
42. Characterization and quantification of oxyntomodulin in human and rat plasma using high-resolution accurate mass LC-MS.
43. Glucagon-Like Peptide-1 Receptor Ligand Interactions: Structural Cross Talk between Ligands and the Extracellular Domain.
44. A Novel Humanized GLP-1 Receptor Model Enables Both Affinity Purification and Cre-LoxP Deletion of the Receptor.
45. Suppression of choroid plexus transthyretin levels by antisense oligonucleotide treatment.
46. Transgenic mice expressing LHX3 transcription factor isoforms in the pituitary: Effects on the gonadotrope axis and sex-specific reproductive disease.
47. Specific Reduction of Hepatic Glucose 6-Phosphate Transporter-1 Ameliorates Diabetes while Avoiding Complications of Glycogen Storage Disease.
48. Erratum. GLP-1 Receptor in Pancreatic α-Cells Regulates Glucagon Secretion in a Glucose-Dependent Bidirectional Manner. Diabetes 2019;68.
49. Correction: A Novel Humanized GLP-1 Receptor Model Enables Both Affinity Purification and Cre-LoxP Deletion of the Receptor.
50. Compound 18 Improves Glucose Tolerance in a Hepatocyte TGR5-dependent Manner in Mice.
Catalog
Books, media, physical & digital resources
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.