1. Spatial Interaction Between Leptospirosis and Enteric Fever in Kelantan, Malaysia: A 2016-2022 Notification Registry Analysis.
- Author
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Mohd Hatta, Hazlienor, Musa, Kamarul Imran, Mohd Fuzi, Nik Mohd Hafiz, and Moraga, Paula
- Subjects
PUBLIC health surveillance ,LEPTOSPIROSIS ,POLYMERASE chain reaction ,POPULATION geography ,RETROSPECTIVE studies ,DISEASE prevalence ,DESCRIPTIVE statistics ,REPORTING of diseases ,LONGITUDINAL method ,AGGLUTINATION tests ,MEDICAL records ,ACQUISITION of data ,RESEARCH ,PUBLIC health ,SPACE perception ,COMPARATIVE studies ,HEALTH promotion ,TYPHOID fever ,MIXED infections ,PREVENTIVE health services ,NONPARAMETRIC statistics ,NEIGHBORHOOD characteristics ,INFECTIOUS disease transmission - Abstract
Leptospirosis and enteric fever are prevalent tropical acute bacterial febrile illnesses in Kelantan, Malaysia, that exhibit overlapping features and shared transmission dynamics, yet their spatial relationship remains understudied. This study aimed to analyze their spatial distribution, investigating potential interactions and intersecting patterns. A total of 212 laboratory-confirmed cases of enteric fever and 1106 of leptospirosis between 2016 and 2022, were retrieved from the national e-Notifikasi registry. Point pattern analysis revealed clustering of both diseases in the northern region, but leptospirosis was predominant in the south, exhibiting higher spatial risk. Seven co-infection cases were identified in overlapping hotspot areas. Spatial dependence between the diseases was identified within 4 km distance on average, with varying patterns over time and regions. Recognizing spatial dependence has implications for accurate diagnosis, timely intervention, and tailored public health strategies. The findings underscore the need for multi-disease interventions to address shared risk factors and co-infections in similar geographical contexts. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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