1. Interleukin-33 in asthma: insights into pro-inflammatory roles of airway structural cells
- Author
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L Al-Awan, David Préfontaine, Andrew J. Halayko, Andrea Mogas, Ronald Olivenstein, Stéphane Lajoie-Kadoch, Jamila Chakir, Severine Audusseau, Catherine Lemière, Qutayba Hamid, James G. Martin, and University of Manitoba
- Subjects
lcsh:Immunologic diseases. Allergy ,Pulmonary and Respiratory Medicine ,Allergy ,business.industry ,medicine.medical_treatment ,General Medicine ,medicine.disease ,respiratory tract diseases ,Interleukin 33 ,Airway disease ,Immune system ,Cytokine ,Immunology ,Poster Presentation ,Medicine ,Immunology and Allergy ,business ,Airway ,Lung tissue ,lcsh:RC581-607 ,Asthma - Abstract
Background Interleukin-33 (IL-33) is a novel cytokine that triggers inflammatory immune responses, but evidence of its role in human asthma, a common allergic airway disease, is lacking. There is also a paucity of information regarding which cells express IL-33, and what conditions promote its expression. We sought to investigate whether IL-33 is expressed in the lung tissue from patients with asthma.
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