29 results on '"Tabo, Mitsuyasu"'
Search Results
2. Involvement of the Autonomic Nervous System in Diurnal Variation of Corrected QT Intervals in Common Marmosets
3. Rapid in vitro assessment of the immunogenicity potential of engineered antibody therapeutics through detection of CD4+ T cell interleukin-2 secretion.
4. Electrophysiological Characterization of Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells
5. Sensitivity of common marmosets to detect drug-induced QT interval prolongation: Moxifloxacin case study
6. Application of probabilistic analysis for precisely correcting the QT interval for heart rate in telemetered common marmosets
7. Monophasic action potential in anaesthetized guinea pigs as a biomarker for prediction of liability for drug-induced delayed ventricular repolarization
8. QT PRODACT: Evaluation of the Potential of Compounds to Cause QT Interval Prolongation by Action Potential Assays Using Guinea-Pig Papillary Muscles
9. QT PRODACT: A Multi-site Study of In Vitro Action Potential Assays on 21 Compounds in Isolated Guinea-Pig Papillary Muscles
10. In vitro human helper T-cell assay to screen antibody drug candidates for immunogenicity.
11. The sulfamide moiety affords higher inhibitory activity and oral bioavailability to a series of coumarin dual selective RAF/MEK inhibitors
12. EFFECTS OF K^+ ON Ca^<2+> INFLUX AFTER DEPLETION OF INTRACELLULAR Ca^<2+> STORES IN ILEAL SMOOTH MUSCLE OF THE RAT
13. Cardiovascular safety profile of MA-2029, a novel motilin receptpr antagonist.
14. Prediction of drug-induced QT interval prolongation in telemetered common marmosets.
15. PRECLINICAL ELECTROPHYSIOLOGY ASSAYS OF MITEMCINAL (GM-611), A NOVEL PROKINETIC AGENT DERIVED FROM ERYTHROMYCIN.
16. HEMODYNAMIC AND ELECTROPHYSIOLOGICAL EFFECTS OF MITEMCINAL (GM-611), A NOVEL PROKINETIC AGENT DERIVED FROM ERYTHROMYCIN IN A HALOTHANE-ANESTHETIZED CANINE MODEL.
17. Application of a probabilistic analytical method to detect drug-induced qt prolongation in telemetered common marmosets: Effects of moxifloxacin
18. Studies of in vivo drug-induced OT interval prolongation in early-stage drug development.
19. Different players generate positive responses in two in vitro cytokine assay formats with aqueous and immobilized TGN1412 analog.
20. Rapid in vitro assessment of the immunogenicity potential of engineered antibody therapeutics through detection of CD4 + T cell interleukin-2 secretion.
21. Prediction of Human Pharmacokinetics Profile of Monoclonal Antibody Using hFcRn Transgenic Mouse Model.
22. Cardiac safety assessment with motion field imaging analysis of human iPS cell-derived cardiomyocytes is improved by an integrated evaluation with cardiac ion channel profiling.
23. Conduction and contraction properties of human iPS cell-derived cardiomyocytes: analysis by motion field imaging compared with the guinea-pig isolated heart model.
24. Is an in vitro whole blood cytokine assay useful to detect the potential risk of severe infusion reaction of monoclonal antibody pharmaceuticals?
25. Estimating the clinical risk of hypertension from VEGF signal inhibitors by a non-clinical approach using telemetered rats.
26. Optimizing the Physicochemical Properties of Raf/MEK Inhibitors by Nitrogen Scanning.
27. Fluorine Scanning by Nonselective Fluorination: Enhancing Raf/MEK Inhibition while Keeping Physicochemical Properties.
28. Accurate detection of drug-induced delayed ventricular repolarization with a suitable correction formula in Langendorff guinea pig heart.
29. QT-RR relationships and suitable QT correction formulas for halothane-anesthetized dogs.
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