148 results on '"Thet, Naing"'
Search Results
2. “Turn-on” and ratiometric detection of carboxylesterases using acetyl-based fluorescent strategies for bacterial applications
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Yan, Kai-Cheng, Guo, Fang-Fang, Zhang, Ling, Thet, Naing, Sedgwick, Adam C., Wang, Yuan, Xu, Zhi-Hong, James, Tony D., and Jenkins, A. Toby A.
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- 2024
- Full Text
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3. Impact load measurement of small multi-bubble explosions near solid wall
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Nyo Me Thet Naing, Seung-Ho Hyun, and Rho-Taek Jung
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Ocean engineering ,TC1501-1800 ,Naval architecture. Shipbuilding. Marine engineering ,VM1-989 - Abstract
The interaction of multiple spark-generated bubbles near solid boundary is investigated experimentally. Qualitative study is done with high-speed imaging for bubble shape evolution and PVDF sensor for impact force measurement. Similar-sized bubbles are created synchronously and distance between bubbles or boundary is chosen to be as small as possible. The jet direction of two horizontally aligned bubbles is strongly influenced by proximity parameter (γ) near boundary. The role of inter bubble distance (η) between bubbles and its contribution to intensity of impulsive force is also presented. It is found that strongest impact is recorded for horizontal pair, compared to vertical pair and diagonal pair, for small η values. Three bubbles are arranged with middle one which is smaller, similar or bigger than left and right bubbles. Allocating bigger bubble in the center indeed produces the most destructive impact on boundary among all cases. Moreover, diverse bubble deformation features are witnessed for various combination of dimensionless parameter applied in this study.
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- 2024
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4. Impact load measurement of small multi-bubble explosions near solid wall
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Thet Naing, Nyo Me, Hyun, Seung-Ho, and Jung, Rho-Taek
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- 2024
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5. Mental Health of University Students in Northern Malaysia
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Theingi Maung Maung, Phyo Thet Naing Win, and Win Oo
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AIMST ,Anxiety ,Depression ,Stress ,University students ,Public aspects of medicine ,RA1-1270 - Abstract
Context/Background: Today, poor mental health is one of the most neglected diseases although it is one of the leading causes of disabilities in both developed and developing countries. This mental health issue becomes a problem among university students too. This study was aimed to determine the prevalence and associated factors of depression, anxiety, and stress (DAS) among university students. Methodology: A cross-sectional study was carried out in a private university of northern Malaysia during 2020. A random sample of 161 students were included and DASS-21 was used to determine the prevalence of DAS. Multiple logistic regression analysis was performed to examine the associated factors. Results: The prevalence of DAS among students were 34.8%, 42.2%, and 33.5%, respectively. In contrast to years 2 and 4, the prevalence of all types of mental disorders were lower in years 1 and 3. The students’ living area, residence, academic year, and parental income were significantly associated with anxiety whereas the age group of the students and parent’s income did so for depression. The variables; age group, academic year and parent’s income were identified as significant determinants for the presence of stress among students. Conclusions: The significant extent of the mental health problems was detected among university students in Malaysia. Despite the small sample, this analysis indicates that opportunities exist to improve campus-based mental health education and psychological support among university students.
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- 2023
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6. Optimisation of a lozenge-based sensor for detecting impending blockage of urinary catheters
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Heylen, Rachel A., Branson, Max, Gwynne, Lauren, Patenall, Bethany L., Hauschildt, Nina, Urie, James, Mercer-Chalmers, June, Thet, Naing T., Laabei, Maisem, and Jenkins, A. Toby A.
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- 2022
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7. Variability in Grading Diabetic Retinopathy Using Retinal Photography and Its Comparison with an Automated Deep Learning Diabetic Retinopathy Screening Software
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Chin Sheng Teoh, Kah Hie Wong, Di Xiao, Hung Chew Wong, Paul Zhao, Hwei Wuen Chan, Yew Sen Yuen, Thet Naing, Kanagasingam Yogesan, and Victor Teck Chang Koh
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automated screening software ,deep learning ,diabetes retinopathy ,grading ,variability ,Medicine - Abstract
Background: Diabetic retinopathy (DR) screening using colour retinal photographs is cost-effective and time-efficient. In real-world clinical settings, DR severity is frequently graded by individuals of different expertise levels. We aim to determine the agreement in DR severity grading between human graders of varying expertise and an automated deep learning DR screening software (ADLS). Methods: Using the International Clinical DR Disease Severity Scale, two hundred macula-centred fundus photographs were graded by retinal specialists, ophthalmology residents, family medicine physicians, medical students, and the ADLS. Based on referral urgency, referral grading was divided into no referral, non-urgent referral, and urgent referral to an ophthalmologist. Inter-observer and intra-group variations were analysed using Gwet’s agreement coefficient, and the performance of ADLS was evaluated using sensitivity and specificity. Results: The agreement coefficient for inter-observer and intra-group variability ranged from fair to very good, and moderate to good, respectively. The ADLS showed a high area under curve of 0.879, 0.714, and 0.836 for non-referable DR, non-urgent referable DR, and urgent referable DR, respectively, with varying sensitivity and specificity values. Conclusion: Inter-observer and intra-group agreements among human graders vary widely, but ADLS is a reliable and reasonably sensitive tool for mass screening to detect referable DR and urgent referable DR.
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- 2023
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8. Impulsive forces of two spark-generated cavity bubbles with phase differences
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Rho-Taek Jung and Nyo Me Thet Naing
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Two-bubble interactions ,Phase differences ,Spark generation ,PVDF ,Impulsive forces ,Chemistry ,QD1-999 ,Acoustics. Sound ,QC221-246 - Abstract
The characteristics of synchronous and phase difference bubble pairs in axisymmetric configuration near a boundary are investigated experimentally by the spark discharge method. Their destructive forces on nearby boundaries are measured using a polyvinylidene fluoride sensor. The bubble pair interactions and deformed features in the boundary vicinity are dissimilar to those in bulk water. Moreover, significant discrepancies between in-phase and out-of-phase pair interactions and their intensities of impulses are also witnessed. The interbubble distance (η), stand-off distance from the boundary (γ), and phase offset (τ) are crucial parameters affecting the shape evolutions and impulsive forces. From the qualitative analysis of sensor acquisition and high-speed imaging, it is observed that bubble periods are either prolonged or shorter than their corresponding isolated single cavity according to different parameters and arrangements. Additionally, the strongest impingements are produced by in-phase pairs. The impulses of phase difference bubble pairs are remarkably lower than in-phase pairs and even lower than a single bubble in some arrangements.
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- 2022
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9. Internet addiction among undergraduate medical students in Myanmar: A cross-sectional study
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Pa Pa Soe, Khin May Oo, Phoo Nay Chi, Phyo Thet Naing Win, and Win Myint Oo
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internet addiction ,medical students ,myanmar ,undergraduate students ,Infectious and parasitic diseases ,RC109-216 - Abstract
Objective: To determine the prevalence of internet addiction and its associated factors among undergraduate students attending medical universities in Myanmar. Methods: Internet addiction was assessed using Young’s internet addiction test. Multiple logistic regression analysis was applied to determine the factors associated with internet addiction. Altogether 950 students from all medical universities were included in the study voluntarily. Result: The prevalence of internet addiction in the study population was 72.2% (95%CI: 69.3%, 75.0%). According to the results of multiple logistic regression analysis, age, percentage of pocket money spent for internet, time spent per day using the internet, peer pressure, health-related behaviours (irregular meals, sleep disturbances, and missing social gatherings), and academic performance (postponement of the study and inability to concentrate on studying) were significant predictors of internet addiction. Conclusions: There is a high prevalence of internet addiction among Myanmar undergraduate medical students. Appropriate interventions, including promotion and strengthening of active and healthy lifestyles among students, should be implemented to prevent internet addiction and its adverse outcomes.
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- 2023
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10. On-demand release of silver from composite hydrogel by cold atmospheric plasma jet for wound infection control.
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Thet, Naing Tun, Patenall, Bethany L., Short, Robert D., and Jenkins, A. Toby A.
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COLD atmospheric plasmas , *PLASMA jets , *STAPHYLOCOCCUS aureus , *INFECTION control , *WOUND infections , *HYDROGELS - Abstract
Silver is an antimicrobial commonly used within wound care chiefly in advanced dressings or in a topical cream form, such as silver sulfadiazine (SSD). Although silver is effective at controlling the growth of many common wound bacteria, it can be cytotoxic and can build up in tissue, stalling the healing process. Here, we demonstrate the development of an on-demand release system for delivery of silver from a composite hydrogel comprising sodium polyacrylate particles dispersed in a cryo-crosslinked polyvinyl alcohol carrier gel. Application of cold atmospheric plasma (CAP) jet to the silver loaded hydrogel resulted in controlled release of silver. This release is thought to occur due to the formation of nitrous acids in the hydrogel by the CAP, resulting in protonation of carboxylate groups in the hydrogel and subsequent gel de-swelling due to the reduction in interchain charge repulsion. The location of silver within the sodium polyacrylate particles was probed using scanning electron microscopy and EDX imaging. The released silver inhibited the growth of Enterococcus faecalis, Pseudomonas aeruginosa, and Staphylococcus aureus and significantly reduced the viable cell count of the P. aeruginosa biofilm. [ABSTRACT FROM AUTHOR]
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- 2024
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11. A small-molecular inhibitor against Proteus mirabilis urease to treat catheter-associated urinary tract infections
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Milo, Scarlet, Heylen, Rachel A., Glancy, John, Williams, George T., Patenall, Bethany L., Hathaway, Hollie J., Thet, Naing T., Allinson, Sarah L., Laabei, Maisem, and Jenkins, A. Toby A.
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- 2021
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12. Peculiarities of γ-Al2O3 Crystallization on the Surface of h-BN Particles
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Sergey N. Grigoriev, Elena A. Trusova, Asya M. Afzal, Thet Naing Soe, Alexandra Yu. Kurmysheva, Ekaterina Kuznetsova, Anton Smirnov, and Nestor Washington Solís Pinargote
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h-BN ,nano-alumina ,sol–gel ,γ-Al2O3@h-BN ,nanostructures ,crystallization on surface ,Technology ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Microscopy ,QH201-278.5 ,Descriptive and experimental mechanics ,QC120-168.85 - Abstract
The main goal of the present work was to synthesize a composite consisting of h-BN particles coated with a γ-Al2O3 nanolayer. A method was proposed for applying nanocrystalline γ-Al2O3 to h-BN particles using a sol–gel technique, which ensures the chemical homogeneity of the composite at the nano level. It has been determined that during crystallization on the h-BN surface, the proportion of spinel in alumina decreases from 40 wt.% in pure γ-Al2O3 to 30 wt.% as a result of the involvement of the B3+ ions from the surface nitride monolayers into the transition complex. For comparison, nano-alumina was synthesized from the same sol under the same conditions as the composite. The characterization of the obtained nanostructured powders was carried out using TEM and XRD. A mechanism is proposed for the formation of a nanostructured γ-Al2O3@h-BN composite during the interaction of Al-containing sol and h-BN suspension in aqueous organic media. The resulting composite is a promising model of powdered raw materials for the development of fine-grained ceramic materials for a wide range of applications.
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- 2022
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13. The Influence of Surface Texturing of Ceramic and Superhard Cutting Tools on the Machining Process—A Review
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Sergey N. Grigoriev, Thet Naing Soe, Khaled Hamdy, Yuri Pristinskiy, Alexander Malakhinsky, Islamutdin Makhadilov, Vadim Romanov, Ekaterina Kuznetsova, Pavel Podrabinnik, Alexandra Yu. Kurmysheva, Anton Smirnov, and Nestor Washington Solís Pinargote
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ceramic cutting tool ,ceramic cutting materials ,superhard cutting tool ,superhard cutting materials ,ultrahard cutting materials ,surface texturing ,Technology ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Microscopy ,QH201-278.5 ,Descriptive and experimental mechanics ,QC120-168.85 - Abstract
Machining is an indispensable manufacturing process for a wide range of engineering materials, such as metals, ceramics, and composite materials, in which the tool wear is a serious problem, which affects not only the costs and productivity but also the quality of the machined components. Thus, the modification of the cutting tool surface by application of textures on their surfaces is proposed as a very promising method for improving tool life. Surface texturing is a relatively new surface engineering technology, where microscale or nanoscale surface textures are generated on the cutting tool through a variety of techniques in order to improve tribological properties of cutting tool surfaces by reducing the coefficient of friction and increasing wear resistance. In this paper, the studies carried out to date on the texturing of ceramic and superhard cutting tools have been reviewed. Furthermore, the most common methods for creating textures on the surfaces of different materials have been summarized. Moreover, the parameters that are generally used in surface texturing, which should be indicated in all future studies of textured cutting tools in order to have a better understanding of its effects in the cutting process, are described. In addition, this paper proposes a way in which to classify the texture surfaces used in the cutting tools according to their geometric parameters. This paper highlights the effect of ceramic and superhard textured cutting tools in improving the machining performance of difficult-to-cut materials, such as coefficient of friction, tool wear, cutting forces, cutting temperature, and machined workpiece roughness. Finally, a conclusion of the analyzed papers is given.
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- 2022
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14. Granulation of Silicon Nitride Powders by Spray Drying: A Review
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Sergey N. Grigoriev, Thet Naing Soe, Alexander Malakhinsky, Islamutdin Makhadilov, Vadim Romanov, Ekaterina Kuznetsova, Anton Smirnov, Pavel Podrabinnik, Roman Khmyrov, Nestor Washington Solís Pinargote, and Alexandra Yu. Kurmysheva
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spray drying ,silicon nitride ,powders ,dispersant ,binder ,solvent ,Technology ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Microscopy ,QH201-278.5 ,Descriptive and experimental mechanics ,QC120-168.85 - Abstract
Spray drying is a widely used method of converting liquid material (aqueous or organic solutions, emulsions and suspensions) into a dry powder. Good flowability, narrow size distribution, and controllable morphology are inherent in powders produced by spray drying. This review considers the granulation factors that influence the final properties of the silicon nitride dried powders. The first group includes the types of atomizers, manifolds, and drying chamber configurations. The process parameters fall into the second group and include the following: inlet temperature, atomizing air flow, feed flow rate, drying gas flow rate, outlet temperature, and drying time. Finally, the last group, feedstock parameters, includes many factors such as feed surface tension, feed viscosity, solvent type, solid particle concentration, and additives. Given the large number of factors affecting morphology, particle size and moisture, optimizing the spray drying process is usually achieved by the “trial and error” approach. Nevertheless, some factors such as the effect of a solvent, dispersant, binder, and sintering additives considered in the literature that affect the Si3N4 granulation process were reviewed in the work. By summarizing the data available on silicon nitride powder production, the authors attempt to tackle the problem of its emerging demand in science and industry.
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- 2022
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15. The evolution of collaborative networks towards more polycentric disaster responses between the 2015 and 2016 Myanmar floods
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Htein, Moe Kyaw, Lim, Seunghoo, and Zaw, Thet Naing
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- 2018
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16. Processing and Characterization of Spark Plasma Sintered SiC-TiB2-TiC Powders
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Sergey N. Grigoriev, Yuri Pristinskiy, Thet Naing Soe, Alexander Malakhinsky, Mikhail Mosyanov, Pavel Podrabinnik, Anton Smirnov, and Nestor Washington Solís Pinargote
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SiC-TiB2-TiC composites ,cutting tool material ,spark plasma sintering ,mechanical properties ,microstructure ,Technology ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Microscopy ,QH201-278.5 ,Descriptive and experimental mechanics ,QC120-168.85 - Abstract
SiC-TiB2-TiC composites with matrices consisting of semiconductor material (SiC), conductive materials (TiB2-TiC), or their combination were fabricated by spark plasma sintering (SPS) at 2000 °C in a vacuum under a pressure of 80 MPa for 3 min. The composition and microstructure of the obtained composites were studied by X-ray diffraction and a scanning electron microscope equipped with an energy-dispersive detector. The flexural strength, Vickers hardness, and fracture toughness of SPSed samples were determined. Based on the observations in this work, three variations of the sintering process were proposed with different matrix compositions. The dense (99.7%) 60SiC-25TiB2-15TiC vol.% sintered ceramic composites exhibited the highest strength and hardness values of the studied composites, as well as a fracture toughness of 6.2 MPa·m1/2.
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- 2022
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17. Modified tethered bilayer lipid membranes for detection of pathogenic bacterial toxins and characterization of ion channels
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Thet, Naing Tun and Jenkins, Andrew
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540 ,Pathogenic bacteria ,alpha hemolysin ,phospholipase ,nanopores ,TBLM - Abstract
Pathogenic bacteria secrete various virulence factors as their biochemical weapons to gain access to and destroy the target cells. They can directly interact with the outer lipid bilayer membrane of eukaryotic cells, inducing the premature cell death by either apoptosis or necrosis. Such virulence factors account for much of the toxic actions associated with bacterial infection; therefore the detection of such proteins could provide a methodology for sensing/detection of pathogenic bacteria in, for example, food or human tissue. Detection and identification of pathogenic bacteria by conventional methods such as plating and counting in laboratory is expensive and time consuming. With growing concerns over emergence and re-emergence of pathogenic bacteria with high resistant to current antibiotics, there is a potential need for effective detection of pathogenic toxins invitro. On the other hand, artificially prepared lipid bilayer membrane on planar metallic surfaces provides the cell membrane mimics which are extremely useful in exploring the cellular functions and processes at the molecular level. Therefore in this work, an application of planar tethered bilayer lipid membrane (pTBLM) as a biomimetic sensing platform for the detection of clinically important pathogens, Staphylococcus aureus and Pseudomonas aeruginosa via their secreted virulence factors was presented. Planar TBLM was modified by incorporation of cholesterol and detection of bacterial toxins at human body temperature was examined by impedance and surface plasmon resonance methods. The results of pathogenic bacterial toxin detection were compared with those of Escherichia coli (DH5α), the human gut normal flora with non-pathogenic strain, as a control. Additionally pTBLM was transferred onto single nanoporous Si3N4 membrane to enhance the toxin sensitivity and extend the lifetime for the possible realization of future membrane chips for ion channel characterizations and drug screenings. Then the single ion channel measurement was demonstrated with nanopore-suspended TBLM (Nano-psTBLM) using α-toxin of S. aureus. The results presented in this work therefore, may pave the more effective and efficient ways for future pathogenic bacterial detection in which the sensing mechanism was solely based on the nature of interactions as well as modes of action between bacterial toxins and artificial lipid bilayer membranes.
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- 2010
18. Modified tethered bulayer lipid membranes for detection of pathogenic bacterial toxins and characterization of ion channels
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Tun, Thet Naing
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571.29 - Published
- 2010
19. The military's role in disaster management and response during the 2015 Myanmar floods: A social network approach
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Zaw, Thet Naing and Lim, Seunghoo
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- 2017
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20. Development and early testing of a simple, low cost, fast sensor for maternal and neonatal group B Streptococcus
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Alsheim, Emelie, Thet, Naing Tun, Laabei, Maisem, and Jenkins, A. Toby A.
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- 2024
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21. A simple coumarin-based system for the effective detection of superoxide in bacteria
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Yan, Kai-Cheng, Cao, Qiao, Thet, Naing, Sedgwick, Adam C., James, Tony D., and Jenkins, A. Toby A.
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- 2024
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22. CHI study: protocol for an observational cohort study on ageing and mental health in community-dwelling older adults
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Lei Feng, Lieng Hsi Ling, Qiushi Feng, Rachael Zhi Yi Lee, Junhong Yu, Iris Rawtaer, Patrick Finbarr Allen, Zhiming Bao, Jeong Kyu Lee, Chin Tat Lim, Leng Leng Thang, Thet Naing, D Y Wang, Kai Zhen Yap, EH Kua, and Rathi Mahendran
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Medicine - Abstract
Introduction Ageing is associated with a multitude of healthcare issues including dementia, depression, frailty, morbidity associated with chronic disease and high healthcare utilisation. With Singapore’s population projected to age significantly over the next two decades, it has become increasingly important to understand the disease burden and etiological process among older adults. The Community Health and Intergenerational study aims to holistically examine ageing in place by investigating the resilience and vulnerability factors of the ageing process in the biological, psychological and social domains within the environment.Methods and analysis Using a cohort multiple randomised controlled trial design, comprehensive health profiles of community-dwelling older adults will be collected. The objective is to recruit 1000 participants (aged 60–99 years) living in the western region of Singapore within a period of 3 years (2018–2020). Assessments include basic sociodemographic, physical health and function (cardiac, oral and blood profiles and visual function), cognitive functioning, daily functioning, physical fitness, emotional state, free-flowing speech, sleep quality, social connectedness, caregiver burden, intergenerational communication, quality of life, life satisfaction, attitudes to ageing and gratitude and compassion. Results from the cohort will enable future studies to identify at-risk groups and develop interventions to improve the physical and mental health and quality of life of older adults.Ethics and dissemination Approval of the cohort study by the National University of Singapore Institutional Review Board (NUS-IRB Reference code: H-17-047) was obtained on 12 October 2017. Written consent will be obtained from all participants. Findings from the cohort study will be disseminated by publication of peer-reviewed manuscripts, presentations at scientific meetings and conferences with local stakeholders.
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- 2020
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23. Systemic Factors Associated with Treatment Response in Diabetic Macular Edema
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Wendy Meihua Wong, Caroline Chee, Mayuri Bhargava, Charmaine Chai, Hazel Lin, Paul Zhao, Erlangga Ariadarma Mangunkusumo, Thet Naing, Yew Sen Yuen, Tien Yin Wong, Xinyi Su, and Gopal Lingam
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Ophthalmology ,RE1-994 - Abstract
Purpose. To identify systemic factors that may influence the response to anti-VEGF therapy in patients with diabetic macular edema (DME). Methods. 35 patients undergoing anti-VEGF injections for centre-involving DME were studied in this prospective observational study. The primary outcome was change in macular thickness one month after treatment, measured using spectral-domain optical coherence tomography (OCT). At baseline, information on various systemic factors was collected including glycosylated hemoglobin (HbA1c), serum VEGF levels, lipid profile and markers of renal function, and blood pressure. Thirty-three of the 35 patients were included in this study. Nonparametric statistical tests were used for the analysis of the data in view of the nonnormal distribution of the outcome variables. Multivariate analysis was performed using logistic regression. Stata 12.1 software was used for the analysis. Main Outcome Measures. Reduction in macular central subfield thickness (on spectral-domain OCT) and change in logMAR visual acuity at one month after injection. Results. Lower HbA1c levels (7% or less) were significantly associated with greater reduction in central macular subfield thickness at one month after injection of bevacizumab or ranibizumab on both univariate analysis (p=0.012) and multivariate analysis (p=0.042). Conclusions. Better glycemic control is associated with a greater reduction in central macular thickness after the first injection of bevacizumab or ranibizumab in diabetic macular edema. Patients with high levels of HbA1c and poor response to anti-VEGF may benefit from strict control of their blood glucose.
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- 2020
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24. Unity 2017 Game AI Programming - Third Edition
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Ray Barrera, Aung Sithu Kyaw, Thet Naing Swe and Ray Barrera, Aung Sithu Kyaw, Thet Naing Swe
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- 2018
25. Investigation of the WEDM Parameters' Influence on the Recast Layer Thickness of Spark Plasma Sintered SiC-TiB 2 -TiC Ceramic.
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Solís Pinargote, Nestor Washington, Malakhinsky, Alexander, Soe, Thet Naing, Pristinskiy, Yuri, Smirnov, Anton, Meleshkin, Yaroslav, Apelfeld, Andrey, Peretyagin, Nikita, Peretyagin, Pavel, and Grigoriev, Sergey N.
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GREY relational analysis ,SURFACE roughness ,CERAMICS - Abstract
The influence of WEDM parameters (Spark gap voltage, Pulse-on time, Spark frequency, and Wire speed) on the recast layer thickness and surface roughness of Spark Plasma Sintered SiC-TiB
2 -TiC ceramic composite was investigated. For this, an orthogonal L9 Taguchi design was used, and grey relational analysis was carried out for multi-response WEDM parameter optimization in order to determine the minimum RLT and SR. It was noticed that for RLT, the Pulse-on time was observed as the most significant process parameter, followed by Spark gap voltage. On the other hand, Spark frequency and Wire speed had no significance for RLT. Moreover, Spark frequency was observed as the most significant process parameter, followed by Pulse-on time and Spark gap voltage, while Wire speed had a negligible effect on SR. It was found that at optimal process parameters (U = 48V; Ton = 1.0 µs; f = 10 kHz; q = 8 m/min), we obtained an RLT of 3.16 µm and an SR of Ra = 0.847 µm. The confirmation test showed a decrease in RLT and SR by 43.67% and 7.12%, respectively, in comparison to the initial machining conditions. [ABSTRACT FROM AUTHOR]- Published
- 2023
- Full Text
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26. Variability in Grading Diabetic Retinopathy Using Retinal Photography and Its Comparison with an Automated Deep Learning Diabetic Retinopathy Screening Software
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Koh, Chin Sheng Teoh, Kah Hie Wong, Di Xiao, Hung Chew Wong, Paul Zhao, Hwei Wuen Chan, Yew Sen Yuen, Thet Naing, Kanagasingam Yogesan, and Victor Teck Chang
- Subjects
automated screening software ,deep learning ,diabetes retinopathy ,grading ,variability - Abstract
Background: Diabetic retinopathy (DR) screening using colour retinal photographs is cost-effective and time-efficient. In real-world clinical settings, DR severity is frequently graded by individuals of different expertise levels. We aim to determine the agreement in DR severity grading between human graders of varying expertise and an automated deep learning DR screening software (ADLS). Methods: Using the International Clinical DR Disease Severity Scale, two hundred macula-centred fundus photographs were graded by retinal specialists, ophthalmology residents, family medicine physicians, medical students, and the ADLS. Based on referral urgency, referral grading was divided into no referral, non-urgent referral, and urgent referral to an ophthalmologist. Inter-observer and intra-group variations were analysed using Gwet’s agreement coefficient, and the performance of ADLS was evaluated using sensitivity and specificity. Results: The agreement coefficient for inter-observer and intra-group variability ranged from fair to very good, and moderate to good, respectively. The ADLS showed a high area under curve of 0.879, 0.714, and 0.836 for non-referable DR, non-urgent referable DR, and urgent referable DR, respectively, with varying sensitivity and specificity values. Conclusion: Inter-observer and intra-group agreements among human graders vary widely, but ADLS is a reliable and reasonably sensitive tool for mass screening to detect referable DR and urgent referable DR.
- Published
- 2023
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27. An in-situ infection detection sensor coating for urinary catheters
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Milo, Scarlet, Thet, Naing Tun, Liu, Dan, Nzakizwanayo, Jonathan, Jones, Brian V., and Jenkins, A. Toby A.
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- 2016
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28. A TCF-based fluorescent probe to determine nitroreductase (NTR) activity for a broad-spectrum of bacterial species.
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Yan, Kai-Cheng, Gardiner, Jordan E., Sedgwick, Adam C., Thet, Naing, Heylen, Rachel A., James, Tony D., Jenkins, A. Toby A., and He, Xiao-Peng
- Subjects
FLUORESCENT probes ,BACTERIAL growth ,SPECIES ,BIOFILMS - Abstract
A nitroreductase (NTR) responsive fluorescent probe with long wavelength fluorescence emission was used to determine the NTR activity of a selection of bacterial species under a range of different bacterial growth conditions ensuring applicability under multiple complex clinical environments, where sensitivity, reaction time, and the detection accuracy were suitable for planktonic cultures and biofilms. [ABSTRACT FROM AUTHOR]
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- 2023
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29. Heavy metal sensitivities of gene deletion strains for ITT1 and RPS1A connect their activities to the expression of URE2, a key gene involved in metal detoxification in yeast.
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Houman Moteshareie, Maryam Hajikarimlou, Alex Mulet Indrayanti, Daniel Burnside, Ana Paula Dias, Clara Lettl, Duale Ahmed, Katayoun Omidi, Tom Kazmirchuk, Nathalie Puchacz, Narges Zare, Sarah Takallou, Thet Naing, Raúl Bonne Hernández, William G Willmore, Mohan Babu, Bruce McKay, Bahram Samanfar, Martin Holcik, and Ashkan Golshani
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Medicine ,Science - Abstract
Heavy metal and metalloid contaminations are among the most concerning types of pollutant in the environment. Consequently, it is important to investigate the molecular mechanisms of cellular responses and detoxification pathways for these compounds in living organisms. To date, a number of genes have been linked to the detoxification process. The expression of these genes can be controlled at both transcriptional and translational levels. In baker's yeast, Saccharomyces cerevisiae, resistance to a wide range of toxic metals is regulated by glutathione S-transferases. Yeast URE2 encodes for a protein that has glutathione peroxidase activity and is homologous to mammalian glutathione S-transferases. The URE2 expression is critical to cell survival under heavy metal stress. Here, we report on the finding of two genes, ITT1, an inhibitor of translation termination, and RPS1A, a small ribosomal protein, that when deleted yeast cells exhibit similar metal sensitivity phenotypes to gene deletion strain for URE2. Neither of these genes were previously linked to metal toxicity. Our gene expression analysis illustrates that these two genes affect URE2 mRNA expression at the level of translation.
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- 2018
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30. The sensitivity of the yeast, Saccharomyces cerevisiae, to acetic acid is influenced by DOM34 and RPL36A
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Bahram Samanfar, Kristina Shostak, Houman Moteshareie, Maryam Hajikarimlou, Sarah Shaikho, Katayoun Omidi, Mohsen Hooshyar, Daniel Burnside, Imelda Galván Márquez, Tom Kazmirchuk, Thet Naing, Paula Ludovico, Anna York-Lyon, Kama Szereszewski, Cindy Leung, Jennifer Yixin Jin, Rami Megarbane, Myron L. Smith, Mohan Babu, Martin Holcik, and Ashkan Golshani
- Subjects
Yeast ,Gene deletion ,HSP ,Protein expression ,Saccharomyces cerevisiae ,Acetic acid ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
The presence of acetic acid during industrial alcohol fermentation reduces the yield of fermentation by imposing additional stress on the yeast cells. The biology of cellular responses to stress has been a subject of vigorous investigations. Although much has been learned, details of some of these responses remain poorly understood. Members of heat shock chaperone HSP proteins have been linked to acetic acid and heat shock stress responses in yeast. Both acetic acid and heat shock have been identified to trigger different cellular responses including reduction of global protein synthesis and induction of programmed cell death. Yeast HSC82 and HSP82 code for two important heat shock proteins that together account for 1–2% of total cellular proteins. Both proteins have been linked to responses to acetic acid and heat shock. In contrast to the overall rate of protein synthesis which is reduced, the expression of HSC82 and HSP82 is induced in response to acetic acid stress. In the current study we identified two yeast genes DOM34 and RPL36A that are linked to acetic acid and heat shock sensitivity. We investigated the influence of these genes on the expression of HSP proteins. Our observations suggest that Dom34 and RPL36A influence translation in a CAP-independent manner.
- Published
- 2017
- Full Text
- View/download PDF
31. Cold Atmospheric Plasma-Activated Composite Hydrogel for an Enhanced and On-Demand Delivery of Antimicrobials.
- Author
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Gaur, Nishtha, Patenall, Bethany L., Ghimire, Bhagirath, Thet, Naing T., Gardiner, Jordan E., Le Doare, Krystal E., Ramage, Gordon, Short, Bryn, Heylen, Rachel A., Williams, Craig, Short, Robert D., and Jenkins, Toby A.
- Published
- 2023
- Full Text
- View/download PDF
32. Characterizing Cellular Responses During Oncolytic Maraba Virus Infection
- Author
-
Golnoush Hassanzadeh, Thet Naing, Tyson Graber, Seyed Mehdi Jafarnejad, David F. Stojdl, Tommy Alain, and Martin Holcik
- Subjects
translation ,eIF5B ,IRES ,XIAP ,Bcl-xL ,MG-1 ,Biology (General) ,QH301-705.5 ,Chemistry ,QD1-999 - Abstract
The rising demand for powerful oncolytic virotherapy agents has led to the identification of Maraba virus, one of the most potent oncolytic viruses from Rhabdoviridae family which displays high selectivity for killing malignant cells and low cytotoxicity in normal cells. Although the virus is readied to be used for clinical trials, the interactions between the virus and the host cells is still unclear. Using a newly developed interferon-sensitive mutant Maraba virus (MG1), we have identified two key regulators of global translation (4E-BP1 and eIF2α) as being involved in the regulation of protein synthesis in the infected cells. Despite the translational arrest upon viral stress, we showed an up-regulation of anti-apoptotic Bcl-xL protein that provides a survival benefit for the host cell, yet facilitates effective viral propagation. Given the fact that eIF5B canonically regulates 60S ribosome subunit end joining and is able to replace the role of eIF2 in delivering initiator tRNA to the 40S ribosome subunit upon the phosphorylation of eIF2α we have tested whether eIF5B mediates the translation of target mRNAs during MG1 infection. Our results show that the inhibition of eIF5B significantly down-regulates the level of Bcl-xL steady-state mRNA, thus indirectly attenuates viral propagation.
- Published
- 2019
- Full Text
- View/download PDF
33. Sensing of pathogenic bacteria based on their interaction with supported bilayer membranes studied by impedance spectroscopy and surface plasmon resonance
- Author
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Tun, Thet Naing, Cameron, Petra J., and Jenkins, A. Tobias A.
- Published
- 2011
- Full Text
- View/download PDF
34. Development of a prototype wound dressing technology which can detect and report colonization by pathogenic bacteria
- Author
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Zhou, Jin, Tun, Thet Naing, Hong, Sung-ha, Mercer-Chalmers, June D., Laabei, Maisem, Young, Amber E.R., and Jenkins, A. Tobias A.
- Published
- 2011
- Full Text
- View/download PDF
35. Scavenger receptor class B type I localizes to a late endosomal compartment
- Author
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Malika Ahras, Thet Naing, and Ruth McPherson
- Subjects
cholesterol ,selective uptake ,late endosomes ,lysosomes ,intracellular trafficking ,Biochemistry ,QD415-436 - Abstract
Scavenger receptor class B type I (SR-BI) has an established role in mediating the selective uptake of cholesterol from HDL in hepatocytes, steroidogenic cells, and other tissues. SR-BI is present on the plasma membrane but also localizes to stable intracellular compartments of unknown function. Using indirect immunofluorescence and subcellular fractionation, we have investigated the subcellular distribution of SR-BI. We report that red fluorescent protein-tagged mouse SR-BI (RFP-mSR-BI) colocalizes with the late endosomal and lysosomal markers, Rab7, LBPA, and Rab9. In addition, endogenous SR-BI is also found on lysosomes and colocalizes with LAMP-2 in primary hepatocytes. Furthermore, we demonstrate that the trafficking of SR-BI through these compartments is Rab7 dependent. Interestingly, filipin staining indicates accumulation of lysosomal cholesterol in SR-BI-deficient (−/−) as compared with wild-type hepatocytes. In addition to its role as a plasma membrane receptor, SR-BI may function in cholesterol trafficking from late endosomes/lysosomes.
- Published
- 2008
- Full Text
- View/download PDF
36. TCF-based fluorescent probe for monitoring superoxide anion produced in bacteria under chloramphenicol- and heat-induced stress.
- Author
-
Yan, Kai-Cheng, Patenall, Bethany L., Gardiner, Jordan E., Heylen, Rachel A., Thet, Naing, He, Xiao-Peng, Sedgwick, Adam C., James, Tony D., and Jenkins, A. Toby A.
- Subjects
FLUORESCENT probes ,SUPEROXIDES ,ENTEROCOCCUS faecalis ,ANIONS ,BACTERIA ,ENTEROCOCCUS ,STAPHYLOCOCCUS aureus ,PSEUDOMONAS aeruginosa - Abstract
We report on a superoxide anion (O
2 ˙− ) responsive fluorescent probe called TCF-OTf. TCF-OTf is able to monitor O2 ˙− production when the bacterial species Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, and Enterococcus faecalis are exposed to chloramphenicol and heat shock at 50 and 58 °C. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
37. Peculiarities of γ-Al 2 O 3 Crystallization on the Surface of h-BN Particles.
- Author
-
Grigoriev, Sergey N., Trusova, Elena A., Afzal, Asya M., Soe, Thet Naing, Kurmysheva, Alexandra Yu., Kuznetsova, Ekaterina, Smirnov, Anton, and Solís Pinargote, Nestor Washington
- Subjects
CRYSTALLIZATION ,NANOCOMPOSITE materials ,SOL-gel processes ,RAW materials ,HOMOGENEITY - Abstract
The main goal of the present work was to synthesize a composite consisting of h-BN particles coated with a γ-Al
2 O3 nanolayer. A method was proposed for applying nanocrystalline γ-Al2 O3 to h-BN particles using a sol–gel technique, which ensures the chemical homogeneity of the composite at the nano level. It has been determined that during crystallization on the h-BN surface, the proportion of spinel in alumina decreases from 40 wt.% in pure γ-Al2 O3 to 30 wt.% as a result of the involvement of the B3+ ions from the surface nitride monolayers into the transition complex. For comparison, nano-alumina was synthesized from the same sol under the same conditions as the composite. The characterization of the obtained nanostructured powders was carried out using TEM and XRD. A mechanism is proposed for the formation of a nanostructured γ-Al2 O3 @h-BN composite during the interaction of Al-containing sol and h-BN suspension in aqueous organic media. The resulting composite is a promising model of powdered raw materials for the development of fine-grained ceramic materials for a wide range of applications. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
38. The Influence of Surface Texturing of Ceramic and Superhard Cutting Tools on the Machining Process—A Review.
- Author
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Grigoriev, Sergey N., Soe, Thet Naing, Hamdy, Khaled, Pristinskiy, Yuri, Malakhinsky, Alexander, Makhadilov, Islamutdin, Romanov, Vadim, Kuznetsova, Ekaterina, Podrabinnik, Pavel, Kurmysheva, Alexandra Yu., Smirnov, Anton, and Solís Pinargote, Nestor Washington
- Subjects
- *
CUTTING tools , *SURFACE texture , *CUTTING machines , *METAL cutting , *MACHINE tools , *SURFACES (Technology) , *CERAMICS - Abstract
Machining is an indispensable manufacturing process for a wide range of engineering materials, such as metals, ceramics, and composite materials, in which the tool wear is a serious problem, which affects not only the costs and productivity but also the quality of the machined components. Thus, the modification of the cutting tool surface by application of textures on their surfaces is proposed as a very promising method for improving tool life. Surface texturing is a relatively new surface engineering technology, where microscale or nanoscale surface textures are generated on the cutting tool through a variety of techniques in order to improve tribological properties of cutting tool surfaces by reducing the coefficient of friction and increasing wear resistance. In this paper, the studies carried out to date on the texturing of ceramic and superhard cutting tools have been reviewed. Furthermore, the most common methods for creating textures on the surfaces of different materials have been summarized. Moreover, the parameters that are generally used in surface texturing, which should be indicated in all future studies of textured cutting tools in order to have a better understanding of its effects in the cutting process, are described. In addition, this paper proposes a way in which to classify the texture surfaces used in the cutting tools according to their geometric parameters. This paper highlights the effect of ceramic and superhard textured cutting tools in improving the machining performance of difficult-to-cut materials, such as coefficient of friction, tool wear, cutting forces, cutting temperature, and machined workpiece roughness. Finally, a conclusion of the analyzed papers is given. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
39. In-patient Care for People with COVID-19 and Diabetes in Myanmar
- Author
-
Khin Saw Than, Aye Aye Aung, Ko Ko, Myo Thet Naing, and Aung Ko Ko
- Subjects
0301 basic medicine ,medicine.medical_specialty ,2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,business.industry ,Endocrinology, Diabetes and Metabolism ,Expert advice ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,education ,Feature Article ,030209 endocrinology & metabolism ,Myanmar ,medicine.disease ,in-patient ,humanities ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Endocrinology ,Family medicine ,Diabetes mellitus ,recommendations ,medicine ,In patient ,business - Abstract
These recommendations are synthesized from international references coupled with expert advice from endocrinologists and doctors caring for patients with COVID-19, to help guide physicians in Myanmar in managing persons with diabetes who are admitted.
- Published
- 2020
40. Granulation of Silicon Nitride Powders by Spray Drying: A Review.
- Author
-
Grigoriev, Sergey N., Soe, Thet Naing, Malakhinsky, Alexander, Makhadilov, Islamutdin, Romanov, Vadim, Kuznetsova, Ekaterina, Smirnov, Anton, Podrabinnik, Pavel, Khmyrov, Roman, Solís Pinargote, Nestor Washington, and Kurmysheva, Alexandra Yu.
- Subjects
- *
SPRAY drying , *GRANULATION , *POWDERS , *SURFACE tension , *SILICON nitride , *AIR flow , *GAS flow , *AQUEOUS solutions - Abstract
Spray drying is a widely used method of converting liquid material (aqueous or organic solutions, emulsions and suspensions) into a dry powder. Good flowability, narrow size distribution, and controllable morphology are inherent in powders produced by spray drying. This review considers the granulation factors that influence the final properties of the silicon nitride dried powders. The first group includes the types of atomizers, manifolds, and drying chamber configurations. The process parameters fall into the second group and include the following: inlet temperature, atomizing air flow, feed flow rate, drying gas flow rate, outlet temperature, and drying time. Finally, the last group, feedstock parameters, includes many factors such as feed surface tension, feed viscosity, solvent type, solid particle concentration, and additives. Given the large number of factors affecting morphology, particle size and moisture, optimizing the spray drying process is usually achieved by the "trial and error" approach. Nevertheless, some factors such as the effect of a solvent, dispersant, binder, and sintering additives considered in the literature that affect the Si3N4 granulation process were reviewed in the work. By summarizing the data available on silicon nitride powder production, the authors attempt to tackle the problem of its emerging demand in science and industry. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
41. CHI study: protocol for an observational cohort study on ageing and mental health in community-dwelling older adults
- Author
-
Rachael Zhi Yi Lee, Iris Rawtaer, Junhong Yu, Lieng Hsi Ling, Qiushi Feng, Ee Heok Kua, Chin Tat Lim, D Y Wang, Kai Zhen Yap, Leng Leng Thang, Patrick Finbarr Allen, Thet Naing, Zhiming Bao, Lei Feng, Jeong Kyu Lee, and Rathi Mahendran
- Subjects
Gerontology ,Male ,Aging ,Epidemiology ,Psychological intervention ,lcsh:Medicine ,Cohort Studies ,Quality of life (healthcare) ,Cognition ,old age psychiatry ,Health care ,Medicine ,Humans ,Disease burden ,Aged ,cardiac epidemiology ,Aged, 80 and over ,Singapore ,business.industry ,Depression ,geriatric medicine ,public health ,lcsh:R ,General Medicine ,Middle Aged ,Mental health ,Mental Health ,Physical Fitness ,Cohort ,Community health ,Quality of Life ,Female ,Independent Living ,business ,Sleep ,Cohort study - Abstract
IntroductionAgeing is associated with a multitude of healthcare issues including dementia, depression, frailty, morbidity associated with chronic disease and high healthcare utilisation. With Singapore’s population projected to age significantly over the next two decades, it has become increasingly important to understand the disease burden and etiological process among older adults. The Community Health and Intergenerational study aims to holistically examine ageing in place by investigating the resilience and vulnerability factors of the ageing process in the biological, psychological and social domains within the environment.Methods and analysisUsing a cohort multiple randomised controlled trial design, comprehensive health profiles of community-dwelling older adults will be collected. The objective is to recruit 1000 participants (aged 60–99 years) living in the western region of Singapore within a period of 3 years (2018–2020). Assessments include basic sociodemographic, physical health and function (cardiac, oral and blood profiles and visual function), cognitive functioning, daily functioning, physical fitness, emotional state, free-flowing speech, sleep quality, social connectedness, caregiver burden, intergenerational communication, quality of life, life satisfaction, attitudes to ageing and gratitude and compassion. Results from the cohort will enable future studies to identify at-risk groups and develop interventions to improve the physical and mental health and quality of life of older adults.Ethics and disseminationApproval of the cohort study by the National University of Singapore Institutional Review Board (NUS-IRB Reference code: H-17-047) was obtained on 12 October 2017. Written consent will be obtained from all participants. Findings from the cohort study will be disseminated by publication of peer-reviewed manuscripts, presentations at scientific meetings and conferences with local stakeholders.
- Published
- 2020
42. RELATIONSHIP BETWEEN PRINCIPALS’ COMMUNICATION STYLE AND SCHOOL CLIMATE
- Author
-
Oo, Thet Naing and Wai, Htarr Htarr
- Abstract
The objectives of this research are to study the prominent communication styles of principals, to study the types of school climate and to investigate relationship between principals’ communication style and school climate in Basic Education High Schools, Sittwe Township, Rakhine State. Quantitative and qualitative methods were used in this study. Principals’ communication style was investigated with seven dimensions of the lexical side of communication styles developed by de Vries et al. (2009). School climate was studied based on five dimensions of Organizational Climate Description Questionnaire for Secondary School (OCDQ-RS) developed by Hoy et al. (1991). 176 teachers from selected Basic Education High Schools participated in this study. Descriptive statistics, Independent Samples t Test, and One-Way ANOVA, and Pearson Correlation were used in this study. The findings indicated that the three principals of School A, B and C practiced most expressiveness style. Niceness was the prominent style in School D and preciseness was the prominent style in School E perceived by teachers. There was no significant difference in principals’ communication styles grouped by gender. It was found that the four schools of A, B, C, and E had closed climate while School D had an open climate. There were no significant differences in teachers’ perceptions on school climate grouped by gender, position, and years of teaching service. There was positively moderate relationship (r=.522**, p0.01) between principals’ communication style and school climate.Keywords: Principals’ Communication Style, School Climate.
- Published
- 2020
43. Systemic Factors Associated with Treatment Response in Diabetic Macular Edema
- Author
-
Thet Naing, Wendy Wong, Erlangga Ariadarma Mangunkusumo, Gopal Lingam, Paul Zhao, Charmaine Chai, Xinyi Su, Mayuri Bhargava, Yew Sen Yuen, Hazel Anne Lin, Caroline Chee, and Tien Yin Wong
- Subjects
medicine.medical_specialty ,Multivariate analysis ,Visual acuity ,Bevacizumab ,genetic structures ,Article Subject ,030209 endocrinology & metabolism ,03 medical and health sciences ,0302 clinical medicine ,Ophthalmology ,medicine ,Glycemic ,Univariate analysis ,medicine.diagnostic_test ,business.industry ,RE1-994 ,eye diseases ,Blood pressure ,Clinical Study ,030221 ophthalmology & optometry ,sense organs ,Ranibizumab ,medicine.symptom ,Lipid profile ,business ,medicine.drug - Abstract
Purpose. To identify systemic factors that may influence the response to anti-VEGF therapy in patients with diabetic macular edema (DME). Methods. 35 patients undergoing anti-VEGF injections for centre-involving DME were studied in this prospective observational study. The primary outcome was change in macular thickness one month after treatment, measured using spectral-domain optical coherence tomography (OCT). At baseline, information on various systemic factors was collected including glycosylated hemoglobin (HbA1c), serum VEGF levels, lipid profile and markers of renal function, and blood pressure. Thirty-three of the 35 patients were included in this study. Nonparametric statistical tests were used for the analysis of the data in view of the nonnormal distribution of the outcome variables. Multivariate analysis was performed using logistic regression. Stata 12.1 software was used for the analysis. Main Outcome Measures. Reduction in macular central subfield thickness (on spectral-domain OCT) and change in logMAR visual acuity at one month after injection. Results. Lower HbA1c levels (7% or less) were significantly associated with greater reduction in central macular subfield thickness at one month after injection of bevacizumab or ranibizumab on both univariate analysis (p=0.012) and multivariate analysis (p=0.042). Conclusions. Better glycemic control is associated with a greater reduction in central macular thickness after the first injection of bevacizumab or ranibizumab in diabetic macular edema. Patients with high levels of HbA1c and poor response to anti-VEGF may benefit from strict control of their blood glucose.
- Published
- 2020
- Full Text
- View/download PDF
44. Contact pressure measurement using silicon-based Al xGa 1− xAs semiconductor pressure sensors
- Author
-
Tun, Thet Naing, Lok, Toh Siew, Jui, Tay Cho, Akkipeddi, Ramam, and Rahman, M.
- Published
- 2005
- Full Text
- View/download PDF
45. Speed Control System of Induction Motor by using Vector Control Method
- Author
-
Soe Sandar Aung and Thet Naing Htun
- Subjects
three-phase squirrel-cage induction motor ,vector control method ,Field orientation control ,Electrical Engineering - Abstract
In the Vector Control method of induction motors, one of the advantages of the separately excited DC motor of being able to decouple the flux control and the torque is thereby opened up. The field orientation control of induction motor allows decoupling the control of magnetic flux and the control of the torque produced by the stator current. To drive three phase squirrel cage induction motor with a constant speed, vector control technique is used. In this paper, the development of speed control system for three phase squirrel cage induction motor using a vector control method is presented and simulation for proposed system is done with the help of MATLAB SIMULINK. Soe Sandar Aung | Thet Naing Htun "Speed Control System of Induction Motor by using Vector Control Method" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-5 , August 2019, URL: https://www.ijtsrd.com/papers/ijtsrd27914.pdf
- Published
- 2019
- Full Text
- View/download PDF
46. Speed Control System of Induction Motor by using Direct Torque Control Method used in Escalator
- Author
-
Soe Sandar Aung and Thet Naing Htun
- Subjects
three-phase squirrel-cage induction motor ,direct torque control method ,Escalator ,Electrical Engineering - Abstract
Escalator is useful and act in the important part to carry passengers to the targeted floors of building. Every escalator must be driven by its own motor and this motor speed must be controled. To drive escalator with a constant speed, direct torque control technique is used to drive three phase squirrel cage induction motor. In this paper, the development of speed control system for three phase squirrel cage induction motor using a direct torque control method is presented and simulation for proposed system is done with the help of MATLAB SIMULINK. Soe Sandar Aung | Thet Naing Htun "Speed Control System of Induction Motor by using Direct Torque Control Method used in Escalator" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-5 , August 2019, URL: https://www.ijtsrd.com/papers/ijtsrd27903.pdf
- Published
- 2019
- Full Text
- View/download PDF
47. Image Processing Techniques for Fingerprint Identification and Classification - A Review
- Author
-
Nilar Htwe and Thet Naing Htwe
- Subjects
Multimedia ,Image processing ,Fingerprint classification ,biometric technology - Abstract
The major contributing factor to biometric technological advancements is fingerprints. Biometric authentication technology works completely for worker time management combined with the ability to acknowledge distinctive behavioral features. The growing popularity for period and enrollment of biometrics based platforms provides several advantages. These terminals can not only display fingerprints, but also some are intended to display the distinctive speech style, finger pattern, head form, or iris of a person. Image processing methods were the finest option for human administration to define fingerprint images. This article provides a study of present image processing research by reviewing methods used to distinguish fingerprints and computer training models used to classify fingerprints. The papers primary objective is to demonstrate the present suggested feature extraction duties for image processing and fingerprint identification computer training methods. This evaluation document will be essential to other fingerprint identification scientists operating in the field of image processing Nilar Htwe | Thet Naing Htwe "Image Processing Techniques for Fingerprint Identification and Classification - A Review" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-5 , August 2019, URL: https://www.ijtsrd.com/papers/ijtsrd26761.pdf
- Published
- 2019
- Full Text
- View/download PDF
48. Speed Control System for BLDC Motor by using Direct Back EMF Detection Mathod
- Author
-
Soe Sandar Aung and Thet Naing Htun
- Subjects
Sensorless BLDC motor ,direct back EMF detection ,Electrical Engineering ,sensorless control system - Abstract
BLDC motors are used in many industrial and traction applications due to high efficiency, low maintenance and high torque. For good performance of BLDC motors, the accurate knowledge of the rotor position is required. The need for the rotor position information in BLDC motors have been satisfied by use of some form of rotor position sensors. But to reduce cost, complexity and also to improve reliability of the system, sensor less drive system is preferred. In this paper, the development of sensor less control system for BLDC motor using a direct back EMF detection method is presented and simulation for proposed system is done with the help of MATLAB SIMULINK. Soe Sandar Aung | Thet Naing Htun "Speed Control System for BLDC Motor by using Direct Back EMF Detection Mathod" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-3 | Issue-5 , August 2019, URL: https://www.ijtsrd.com/papers/ijtsrd26624.pdf
- Published
- 2019
- Full Text
- View/download PDF
49. Characterizing Cellular Responses During Oncolytic Maraba Virus Infection
- Author
-
Thet Naing, Golnoush Hassanzadeh, Tommy Alain, Seyed Mehdi Jafarnejad, David F. Stojdl, Tyson E. Graber, and Martin Holcik
- Subjects
0301 basic medicine ,viruses ,Eukaryotic Initiation Factor-2 ,bcl-X Protein ,translation ,Catalysis ,Virus ,Article ,Inorganic Chemistry ,lcsh:Chemistry ,03 medical and health sciences ,0302 clinical medicine ,XIAP ,IRES ,Protein biosynthesis ,Humans ,Eukaryotic Small Ribosomal Subunit ,eIF5B ,RNA, Messenger ,Physical and Theoretical Chemistry ,Eukaryotic Initiation Factors ,Phosphorylation ,Molecular Biology ,lcsh:QH301-705.5 ,Spectroscopy ,Oncolytic Virotherapy ,eIF2 ,biology ,Bcl-xL ,Organic Chemistry ,Translation (biology) ,General Medicine ,Rhabdoviridae ,Ribosome Subunits, Large, Eukaryotic ,biology.organism_classification ,Virology ,3. Good health ,Computer Science Applications ,Oncolytic virus ,Internal ribosome entry site ,Oncolytic Viruses ,MG-1 ,030104 developmental biology ,lcsh:Biology (General) ,lcsh:QD1-999 ,030220 oncology & carcinogenesis ,Protein Biosynthesis - Abstract
The rising demand for powerful oncolytic virotherapy agents has led to the identification of Maraba virus, one of the most potent oncolytic viruses from Rhabdoviridae family which displays high selectivity for killing malignant cells and low cytotoxicity in normal cells. Although the virus is readied to be used for clinical trials, the interactions between the virus and the host cells is still unclear. Using a newly developed interferon-sensitive mutant Maraba virus (MG1), we have identified two key regulators of global translation (4E-BP1 and eIF2&alpha, ) as being involved in the regulation of protein synthesis in the infected cells. Despite the translational arrest upon viral stress, we showed an up-regulation of anti-apoptotic Bcl-xL protein that provides a survival benefit for the host cell, yet facilitates effective viral propagation. Given the fact that eIF5B canonically regulates 60S ribosome subunit end joining and is able to replace the role of eIF2 in delivering initiator tRNA to the 40S ribosome subunit upon the phosphorylation of eIF2&alpha, we have tested whether eIF5B mediates the translation of target mRNAs during MG1 infection. Our results show that the inhibition of eIF5B significantly down-regulates the level of Bcl-xL steady-state mRNA, thus indirectly attenuates viral propagation.
- Published
- 2019
50. Assessment of mutations induced by cold atmospheric plasma jet treatment relative to known mutagens in Escherichia coli.
- Author
-
Patenall, Bethany L, Hathaway, Hollie J, Laabei, Maisem, Young, Amber E, Thet, Naing T, Jenkins, A Toby A, Short, Robert D, and Allinson, Sarah L
- Subjects
MUTAGENS ,PLASMA jets ,LOW temperature plasmas ,ESCHERICHIA coli ,AMES test ,PHENOTYPES - Abstract
The main bactericidal components of cold atmospheric plasma (CAP) are thought to be reactive oxygen and nitrogen species (RONS) and UV-radiation, both of which have the capacity to cause DNA damage and mutations. Here, the mutagenic effects of CAP on Escherichia coli were assessed in comparison to X- and UV-irradiation. DNA damage and mutagenesis were screened for using a diffusion-based DNA fragmentation assay and modified Ames test, respectively. Mutant colonies obtained from the latter were quantitated and sequenced. CAP was found to elicit a similar mutation spectrum to X-irradiation, which did not resemble that for UV implying that CAP-produced RONS are more likely the mutagenic component of CAP. CAP treatment was also shown to promote resistance to the antibiotic ciprofloxacin. Our data suggest that CAP treatment has mutagenic effects that may have important phenotypic consequences. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
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