89 results on '"Tran, Thu-Ha"'
Search Results
2. Executive and non-executive employee ownership and bank risk: Evidence from European banks
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Lepetit, Laetitia, Tran, Phan Huy Hieu, and Tran, Thu Ha
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- 2023
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- View/download PDF
3. Stock markets' reaction to COVID-19: the joint impact of uncertainty avoidance culture and government response–evidence from emerging countries
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Tran, Phan Huy Hieu and Tran, Thu Ha
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- 2023
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4. Implications for Bank Risk when Directors are Related to Minority Shareholders
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Barry, Thierno Amadou, Lepetit, Laetitia, Strobel, Frank, and Tran, Thu Ha
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- 2022
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5. BMX, a specific HDAC8 inhibitor, with TMZ for advanced CRC therapy: a novel synergic effect to elicit p53-, β-catenin- and MGMT-dependent apoptotic cell death
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Ko, Huey-Jiun, Chiou, Shean-Jaw, Tsai, Cheng-Yu, Loh, Joon-Khim, Lin, Xin-Yi, Tran, Thu-Ha, Hou, Chia-Chung, Cheng, Tai-Shan, Lai, Jin-Mei, Chang, Peter Mu-Hsin, Wang, Feng-Sheng, Su, Chun-Li, Huang, Chi-Ying F., and Hong, Yi-Ren
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- 2022
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6. Normal values for high-resolution anorectal manometry in healthy young adults: evidence from Vietnam
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Le Manh Cuong, Ha Van Quyet, Tran Manh Hung, Nguyen Ngoc Anh, Tran Thu Ha, Vu Van Du, Do Van Loi, Ha Huu Hoang Khai, and Vu Duy Kien
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High-resolution anorectal manometry ,Anorectal manometry ,Normal values ,Healthy young people ,Vietnam ,Diseases of the digestive system. Gastroenterology ,RC799-869 - Abstract
Abstract Background High-resolution anorectal manometry (HRAM) has been developed to improve measurement of anorectal functions. This study aims to identify normal HRAM values in healthy young Vietnamese adults. Methods We conducted a cross-sectional study at the National Hospital of Traditional Medicine (Hanoi, Vietnam) from July through December 2014. Healthy young adults were invited to participate in the study. All anorectal measurement values were performed using the ISOLAB high-resolution manometry system. Differences between groups were analyzed using Student’s t-tests. Results Thirty healthy young adults, including 15 males and 15 females aged 19–26 years, were recruited. Mean functional anal canal length was 3.4 ± 0.5 cm (range: 2.4–4.8 mm). Mean maximum resting pressure, mean maximum squeezing pressure, mean maximum coughing pressure, and mean maximum strain pressure were 65.5, 168.0, 125.9, and 84.2 mm Hg, respectively. All anal pressure values were significantly different between males and females. For rectal sensation measurements, only the volume at first sensation was significantly higher in males than in females. Conclusions This study provides normal HRAM value for healthy young adults in Vietnam. Sex may influence anal pressure and first rectal sensation values in this cohort. Further studies should be conducted in order to improve the quality of HRAM normal values and to confirm the effects of sex.
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- 2021
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7. Metastable 1T′-phase group VIB transition metal dichalcogenide crystals
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Lai, Zhuangchai, He, Qiyuan, Tran, Thu Ha, Repaka, D. V. Maheswar, Zhou, Dong-Dong, Sun, Ying, Xi, Shibo, Li, Yongxin, Chaturvedi, Apoorva, Tan, Chaoliang, Chen, Bo, Nam, Gwang-Hyeon, Li, Bing, Ling, Chongyi, Zhai, Wei, Shi, Zhenyu, Hu, Dianyi, Sharma, Vinay, Hu, Zhaoning, Chen, Ye, Zhang, Zhicheng, Yu, Yifu, Renshaw Wang, Xiao, Ramanujan, Raju V., Ma, Yanming, Hippalgaonkar, Kedar, and Zhang, Hua
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- 2021
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8. How employee share ownership plans impact firms' market value: A conflict of interest theory approach.
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Tran, Phan Huy Hieu, Tran, Thu Ha, and Lee, Ji‐Yong
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EMPLOYEE ownership ,MARKET value ,PERCEIVED benefit ,INVESTORS ,CORPORATE banking - Abstract
We investigated whether the market places a higher value on banks with employee share ownership plans (ESOPs) than on those without them. Using a variety of empirical models, we found that ESOPs increased the market value of banks. However, this positive effect occurred only when banks were transparent or located in countries with strong shareholder protection. Our findings demonstrated that if banks were opaque or shareholder protection was weak, outside investors' concerns about managerial entrenchment in widely held banks and behind‐the‐scenes relationships between majority shareholders and managers in closely held banks outweighed the perceived benefits of ESOPs. Our study contributes to the literature by proposing a novel approach to study the effects of ESOPs through the prism of conflict of interest theory. Our findings also shed light on stakeholders' rationales for opposing or adopting ESOPs. [ABSTRACT FROM AUTHOR]
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- 2024
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9. Solvent exchange as a synthetic handle for controlling molecular crystals
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Wang, Shaoyan, Lai, Zhuangchai, Tran, Thu Ha, Han, Fei, Su, Dongmeng, Wang, Ruoxu, Zhang, Hua, Wang, Hong, and Chen, Hongyu
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- 2020
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10. Egret Swarm Optimization Algorithm: An Evolutionary Computation Approach for Model Free Optimization
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Zuyan Chen, Adam Francis, Shuai Li, Bolin Liao, Dunhui Xiao, Tran Thu Ha, Jianfeng Li, Lei Ding, and Xinwei Cao
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metaheuristic algorithm ,swarm intelligence ,egret swarm optimization algorithm ,constrained optimization ,Technology - Abstract
A novel meta-heuristic algorithm named Egret Swarm Optimization Algorithm (ESOA) is proposed in this paper, which is inspired by two egret species’ hunting behavior (Great Egret and Snowy Egret). ESOA consists of three primary components: a sit-and-wait strategy, aggressive strategy as well as discriminant conditions. The learnable sit-and-wait strategy guides the egret to the most probable solution by applying a pseudo gradient estimator. The aggressive strategy uses random wandering and encirclement mechanisms to allow for optimal solution exploration. The discriminant model is utilized to balance the two strategies. The proposed approach provides a parallel framework and a strategy for parameter learning through historical information that can be adapted to most scenarios and has well stability. The performance of ESOA on 36 benchmark functions as well as 3 engineering problems are compared with Particle Swarm Optimization (PSO), Genetic Algorithm (GA), Differential Evolution (DE), Grey Wolf Optimizer (GWO), and Harris Hawks Optimization (HHO). The result proves the superior effectiveness and robustness of ESOA. ESOA acquires the winner in all unimodal functions and reaches statistic scores all above 9.9, while the scores are better in complex functions as 10.96 and 11.92.
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- 2022
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11. Mutation spectrum of retinoblastoma patients in Vietnam.
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Linh, Dao Nguyen Ha, Van Huy, Nguyen, Nguyen, Phuoc‐Dung, Le Thi, Phuong, Tuan, Hoang Anh, Van Nguyen, Trong, Tran, Thu Ha, Tran, Hai Anh, Ta, Thanh Dat, Pham, Tuan L. A., Bui, The‐Hung, Tran, Thinh Huy, Van Ta, Thanh, and Tran, Van‐Khanh
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GENETIC testing ,NONSENSE mutation ,RETINOBLASTOMA ,GENETIC mutation ,GENETIC counseling ,RNA splicing ,GENE amplification - Abstract
Background: Retinoblastoma (RB), an intraocular malignancy commonly diagnosed in children, is mostly caused by inactivating mutations of both alleles of the RB1 gene. Early genetic screening for RB1 gene mutations would greatly improve treatment outcomes and patient management. Methods: In this study, both somatic and germline mutations were detected in blood and tumour samples of 42 RB patients using direct sequencing and multiplex ligation‐dependent probe amplification. Results: In total, 34 different mutations were found in 36 patients, including 1 SNP, 4 large deletions, 5 splicing sites, 1 missense, 7 frameshifts and 17 nonsense mutations. There were five novel mutations and one unreported which have not been found in large databases such as Leiden Open Variation Database (LOVD) and ClinVar. Conclusion: A higher rate of RB patients carrying heterozygous germline mutation and highly prevalent with pathogenic truncated mutation, hence, early detection of RB is essential for vision salvation and genetic counselling. [ABSTRACT FROM AUTHOR]
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- 2023
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12. Hybrid Electrolyte Design for High‐Performance Zinc–Sulfur Battery.
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Guo, Yuqi, Chua, Rodney, Chen, Yingqian, Cai, Yi, Tang, Ernest Jun Jie, Lim, J. J. Nicholas, Tran, Thu Ha, Verma, Vivek, Wong, Ming Wah, and Srinivasan, Madhavi
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- 2023
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13. Water pollution estimation based on the 2D transport–diffusion model and the Singular Evolutive Interpolated Kalman filter
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Tran, Thu Ha, Pham, Dinh Tuan, Hoang, Van Lai, and Nguyen, Hong Phong
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- 2014
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14. Neural networks singular evolutive interpolated Kalman filter and its application to data assimilation for 2D water pollution model.
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Tran, Thu Ha, Shutyaev, Victor, Hoang, Hong Son, Li, Shuai, Nguyen, Chinh Kien, Nguyen, Hong Phong, and Duong, Thi Thanh Huong
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WATER pollution , *OPTIMIZATION algorithms , *NUMERICAL integration , *STOCHASTIC approximation , *DYNAMICAL systems , *KALMAN filtering - Abstract
The present study promotes a new algorithm for estimating the water pollution propagation with the primary goal of providing more reliable and high quality estimates to decision makers. To date, the widely used variational method suffers from the large computational burden, which limits its application in practice. Moreover, this method, considering the initial state as a control variable, is very sensitive in specifying initial error, especially for unstable dynamical systems. The Neural Network Filter (NNF), proposed in the present paper, is aimed at overcoming these two drawbacks in the variational method: by its nature, the NNF is sequential (no batch large assimilation window used) and stable even for unstable dynamics, with the gain parameters as control variables. The NNF, developed in the present paper, is a Neural Network Filter (NNF) version of the Singular Evolutive Interpolated Kalman Filter (SEIKF). One of the new versions of this NNF is that it uses structure of the gain of SEIKF0 taken by the SEIKF at the first time moment of correction process. To deal with the uncertainty of the system parameters and of the noise covariance, the proposed Neural Network SEIKF0 named by NNSEIKF0 makes use of the covariance of a reduced rank iterated during assimilation process and of some pertinent gain parameters tuned adaptively to yield the minimum prediction error for the system output. The computational burden in implementation of the NNSEIKF0 is reduced drastically due to applying the optimization tool known as a simultaneous perturbation stochastic approximation (SPSA) algorithm, which requires only two integrations of the numerical model. No iterative loop is required at each assimilation instant as usually happens with the standard gradient descent optimization algorithms. Data assimilation experiment, carried out by the SEIKF0 and NNSEIKF0, is implemented for the Thanh Nhan Lake in Hanoi and the performance comparison between the NNSEIKF0 and SEIKF0 is given to show the high efficiency of the proposed NNSEIKF0. [ABSTRACT FROM AUTHOR]
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- 2023
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15. Greater length-for-age increases the odds of attaining motor milestones in Vietnamese children aged 5-18 months
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Kulkarni, Shibani, Ramakrishnan, Usha, Dearden, Kirk A, Marsh, David R, Tran, Thu Ha, Tran, Thach Duc, and Pachon, Helena
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- 2012
16. A new phenylethyl glycoside and a new dibenzocyclooctadiene lignan from the leaves of Kadsura coccinea (Lem.) A. C. Smith
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Le, Huyen Tram, Tran, Thu Huong, Le, Thi Thuy, Nguyen, Van Thong, Nguyen, Tuan Anh, Nguyen, Hoang Minh, Tran, Thi Minh, Nguyen, Thi Hong Phuong, Tran, Thu Ha, Nguyen, Hai Dang, Le, Duc Dat, Pham, Phuoc Dien, and Lee, Mina
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- 2021
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17. Agallochin P, a new diterpene from Vietnamese mangrove Excoecaria agallocha L.
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Le Huyen, Tram, Nguyen, Van Thong, Nguyen, Hoang Minh, Nguyen, Tuan Anh, Tran, Thuong Quang, Tran, Thu Ha, and Tran, Thu Huong
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MANGROVE plants ,DATA analysis ,PROBABILITY theory - Abstract
A new diterpene (1) along with eight known compounds (2-9) were isolated from Excoecaria agallocha leaves. The structure and relative configuration of new compound were established on the basis of spectroscopic data analysis and confirmed by NMR chemical shifts calculation with DP4+ probability. Cytotoxicity of the isolated compounds were also evaluated. [ABSTRACT FROM AUTHOR]
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- 2022
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18. A Novel Allele-Specific PCR Protocol for the Detection of the HLA-C*03:02 Allele, a Pharmacogenetic Marker, in Vietnamese Kinh People
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Ngoc Phuong Mai Tran, Thi Quynh Nga Do, Quang Binh Tran, Chonlaphat Sukasem, Thanh Huong Phung, Van Dinh Nguyen, Chi Hieu Chu, and Tran Thu Ha Pham
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0301 basic medicine ,Genetics ,Human leukocyte antigen ,Biology ,Zygosity ,03 medical and health sciences ,HLA-C ,030104 developmental biology ,0302 clinical medicine ,The Application of Clinical Genetics ,Genotype ,Typing ,Allele ,Variants of PCR ,030217 neurology & neurosurgery ,Genetics (clinical) ,Pharmacogenetics - Abstract
Tran Thu Ha Pham,1 Quang Binh Tran,2 Chonlaphat Sukasem,3– 5 Van Dinh Nguyen,6,7 Chi Hieu Chu,8 Thi Quynh Nga Do,9 Ngoc Phuong Mai Tran,9 Thanh Huong Phung1 1Hanoi University of Pharmacy, Hanoi, Vietnam; 2National Institute of Nutrition, Hanoi, Vietnam; 3Division of Pharmacogenomics and Personalized Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 4Laboratory for Pharmacogenomics, Somdech Phra Debaratana Medical Center (SDMC), Ramathibodi Hospital, Bangkok, Thailand; 5The Thai Severe Cutaneous Adverse Drug Reaction (THAI-SCAR) Research Group, Bangkok, Thailand; 6Respiratory, Allergy and Clinical Immunology Unit, Internal Medicine Department, Vinmec Times City International Hospital, Vinmec Healthcare System, Hanoi, Vietnam; 7College of Health Sciences, VinUniversity, Hanoi, Vietnam; 8Center of Allergology and Clinical Immunology, Bach Mai Hospital, Hanoi, Vietnam; 9National Institute of Hygiene and Epidemiology, Hanoi, VietnamCorrespondence: Thanh Huong Phung; Quang Binh Tran Tel +84 904112588; +84 904470844Email huongpt@hup.edu.vn; tranquangbinh@dinhduong.org.vnBackground: Allopurinol, a common anti-hyperuricemia drug, is well known as an inducer of severe cutaneous adverse drug reactions (SCARs). One of the most well-defined risk factors of allopurinol-induced SCARs is the presence of polymorphic alleles of human leukocyte antigen (HLA) genes, such as HLA-B*58:01 and HLA-C*03:02 alleles. There is no commercial test or published in-house protocol for the specific detection of the HLA-C*03:02 allele. In this article, we established for the first time a simple allele-specific (AS) PCR method to identify HLA-C*03:02 allele carriers, and at the same time, determine their zygosities.Methods: A two-step AS-PCR protocol, using four primer sets, was designed to specifically amplify and differentiate the HLA-C*03:02 allele from 17 other HLA-C alleles found in Vietnamese people. The protocol was validated with PCR-sequencing-based typing (SBT) of 100 samples of unknown genotypes.Results: The PCR protocol can detect the HLA-C*03:02 allele and determine the zygosity. The results of this protocol were highly consistent with those of the SBT (ĸ = 0.98, p < 0.001). Regarding the specific detection of the HLA-C*03:02 allele, the PCR protocol had a sensitivity of 100% (95% CI: 91.61– 100%) and specificity of 98.3% (95% CI: 90.9– 99.7%). The protocol was used to determine the distribution of the HLA-C*03:02 allele in 810 unrelated Vietnamese Kinh people, 14.2% of which were HLA-C*03:02 carriers, the allele frequency was 7.5%.Conclusion: A novel AS-PCR protocol with a sensitivity of 100% for the detection of the HLA-C*03:02 allele was established. The protocol can be used for personalized treatment with allopurinol in order to minimize the risk of SCARs in Vietnamese people as well as in other Asian populations with similar genetic characteristics.Keywords: severe cutaneous adverse reactions, HLA-C*03:02, allopurinol, HLA genotyping, AS-PCR
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- 2021
19. An adaptive fuzzy logic controller for robot-manipulator
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Tran Thu Ha, Ho Dac Loc, and Ngo Cao Cuong
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Adaptive fuzzy logic controller ,robot-manipulator ,optimal control ,Electronics ,TK7800-8360 ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
In this paper, an adaptive fuzzy controller is designed for the robot-manipulator. The synthesized controller ensures that 1) the close-loop system is globally stable and 2) the tracking error converges to zero asymptotically and a cost function is minimized. The fuzzy controller is synthesized from a collection of IF-THEN rules. The parameters of the membership functions characterizing the linguistic terms change according to some adaptive law for the purpose of controlling a plant to track a reference trajectory. The proposed control scheme is demonstrated in a typical nonlinear plant two link manipulator. The computer simulation of control is done by the language MATLAB. The results of simulation show that the adaptipresented results are analyzed.
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- 2008
20. The Stunting Tool for Early Prevention: development and external validation of a novel tool to predict risk of stunting in children at 3 years of age
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Tran Thu Ha, Tran Tuan, Jane Fisher, Thach Duc Tran, Sabine Braat, Julie A. Simpson, Beverley-Ann Biggs, and Sarah Hanieh
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prevention strategies ,Psychological intervention ,Logistic regression ,lcsh:Infectious and parasitic diseases ,03 medical and health sciences ,0302 clinical medicine ,medicine ,lcsh:RC109-216 ,030212 general & internal medicine ,Prospective cohort study ,Pregnancy ,Stunting ,lcsh:R5-920 ,Receiver operating characteristic ,business.industry ,030503 health policy & services ,Health Policy ,Research ,Public Health, Environmental and Occupational Health ,Gestational age ,medicine.disease ,Confidence interval ,child health ,medicine.symptom ,0305 other medical science ,business ,lcsh:Medicine (General) ,Weight gain ,Demography - Abstract
IntroductionGlobally, an estimated 151 million children under 5 years of age still suffer from the adverse effects of stunting. We sought to develop and externally validate an early life predictive model that could be applied in infancy to accurately predict risk of stunting in preschool children.MethodsWe conducted two separate prospective cohort studies in Vietnam that intensively monitored children from early pregnancy until 3 years of age. They included 1168 and 475 live-born infants for model development and validation, respectively. Logistic regression on child stunting at 3 years of age was performed for model development, and the predicted probabilities for stunting were used to evaluate the performance of this model in the validation data set.ResultsStunting prevalence was 16.9% (172 of 1015) in the development data set and 16.4% (70 of 426) in the validation data set. Key predictors included in the final model were paternal and maternal height, maternal weekly weight gain during pregnancy, infant sex, gestational age at birth, and infant weight and length at 6 months of age. The area under the receiver operating characteristic curve in the validation data set was 0.85 (95% Confidence Interval, 0.80–0.90).ConclusionThis tool applied to infants at 6 months of age provided valid prediction of risk of stunting at 3 years of age using a readily available set of parental and infant measures. Further research is required to examine the impact of preventive measures introduced at 6 months of age on those identified as being at risk of growth faltering at 3 years of age.
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- 2019
21. New Techniques for Studying the Intercalation of Kaolinites from Georgia with Formamide
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Frost, Ray L., Lack, Daniel A., Paroz, Gina N., and Tran, Thu Ha T.
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- 1999
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22. An adaptive fuzzy logic controller for robot-manipulator
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Ho Dac Loc, Tran Thu Ha, and Ngo Cao Cuong
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Electronics ,TK7800-8360 ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
In this paper, an adaptive fuzzy controller is designed for the robot-manipulator. The synthesized controller ensures that 1) the close-loop system is globally stable and 2) the tracking error converges to zero asymptotically and a cost function is minimized. The fuzzy controller is synthesized from a collection of IF-THEN rules. The parameters of the membership functions characterizing the linguistic terms change according to some adaptive law for the purpose of controlling a plant to track a reference trajectory. The proposed control scheme is demonstrated in a typical nonlinear plant two link manipulator. The computer simulation of control is done by the language MATLAB. The results of simulation show that the adaptive controller well operates and provides good qualities of the control system. The presented results are analyzed.
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- 2004
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23. Small vibrations of a linearly elastic body surrounded by heavy, incompressible, non-Newtonian fluids with free surfaces
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Licht, Christian and Tran Thu Ha
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- 2005
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24. The Effectiveness of Oral Mini-Pulse Methylprednisolonein - the Treatment of Alopecia Areata in Vietnam
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Phuong Trinh Thi, Van Tran Cam, Anh Tran Lan, Phuong Tran Thu Ha, Thuong Nguyen Van, Phuong Pham Thi Minh, Hao Nguyen Trong, Tro Chau Van, Nghi Dinh Huu, My Le Huyen, Khang Tran Hau, Marco Gandolfi, Francesca Satolli, Claudio Feliciani, Michael Tirant, Aleksandra Vojvodic, and Torello Lotti
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medicine.medical_specialty ,medicine.drug_class ,Prednisolone ,lcsh:Medicine ,030209 endocrinology & metabolism ,03 medical and health sciences ,0302 clinical medicine ,Pharmacotherapy ,Oral administration ,medicine ,030212 general & internal medicine ,alopecia areata ,Adverse effect ,skin and connective tissue diseases ,integumentary system ,Pulse (signal processing) ,business.industry ,lcsh:R ,General Medicine ,Clinical Science ,Alopecia areata ,medicine.disease ,Dermatology ,stomatognathic diseases ,Methylprednisolone ,Corticosteroid ,business ,medicine.drug - Abstract
BACKGROUND: Systemic corticosteroid is used to treat alopecia areata, but it is associated with side effects. Mini-pulse therapy is thought to be effective but able to reduce side effects. AIM: The study aimed to evaluate the effectiveness of oral mini-pulse methylprednisolone in the treatment of alopecia areata. METHODS: Patients received methylprednisolone 16 mg orally for 2 consecutive days every week. RESULTS: After 3 months, among patients, 40% recovered well, and 55.6% recovered fairly. After 6 months, 82.2% recovered well, 17.8% recovered fairly. No adverse events were detected, and the recurrence rate was low (2.2%). CONCLUSION: Oral mini-pulse methylprednisolone therapy is an effective and safe therapeutic option for alopecia areata without side effects, and the time of the treatment is short.
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- 2019
25. High‐Yield Exfoliation of Ultrathin 2D Ni3Cr2P2S9 and Ni3Cr2P2Se9 Nanosheets.
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Lai, Zhuangchai, Chaturvedi, Apoorva, Shi, Zhenyu, Zhao, Jiangqi, Tran, Thu Ha, Chen, Bo, Huang, Ying, Cao, Xiehong, He, Qiyuan, Zeng, Zhiyuan, Tan, Chaoliang, and Zhang, Hua
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- 2021
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26. A Novel Allele-Specific PCR Protocol for the Detection of the HLA-C*03:02 Allele, a Pharmacogenetic Marker, in Vietnamese Kinh People.
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Pham, Tran Thu Ha, Tran, Quang Binh, Sukasem, Chonlaphat, Nguyen, Van Dinh, Chu, Chi Hieu, Do, Thi Quynh Nga, Tran, Ngoc Phuong Mai, and Phung, Thanh Huong
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ALLELES ,DRUG side effects ,HLA histocompatibility antigens ,KILLER cell receptors ,VIETNAMESE people ,GENES - Abstract
Background: Allopurinol, a common anti-hyperuricemia drug, is well known as an inducer of severe cutaneous adverse drug reactions (SCARs). One of the most well-defined risk factors of allopurinol-induced SCARs is the presence of polymorphic alleles of human leukocyte antigen (HLA) genes, such as HLA-B*58:01 and HLA-C*03:02 alleles. There is no commercial test or published in-house protocol for the specific detection of the HLA-C*03:02 allele. In this article, we established for the first time a simple allele-specific (AS) PCR method to identify HLA-C*03:02 allele carriers, and at the same time, determine their zygosities. Methods: A two-step AS-PCR protocol, using four primer sets, was designed to specifically amplify and differentiate the HLA-C*03:02 allele from 17 other HLA-C alleles found in Vietnamese people. The protocol was validated with PCR-sequencing-based typing (SBT) of 100 samples of unknown genotypes. Results: The PCR protocol can detect the HLA-C*03:02 allele and determine the zygosity. The results of this protocol were highly consistent with those of the SBT (ĸ = 0.98, p < 0.001). Regarding the specific detection of the HLA-C*03:02 allele, the PCR protocol had a sensitivity of 100% (95% CI: 91.61– 100%) and specificity of 98.3% (95% CI: 90.9– 99.7%). The protocol was used to determine the distribution of the HLA-C*03:02 allele in 810 unrelated Vietnamese Kinh people, 14.2% of which were HLA-C*03:02 carriers, the allele frequency was 7.5%. Conclusion: A novel AS-PCR protocol with a sensitivity of 100% for the detection of the HLA-C*03:02 allele was established. The protocol can be used for personalized treatment with allopurinol in order to minimize the risk of SCARs in Vietnamese people as well as in other Asian populations with similar genetic characteristics. [ABSTRACT FROM AUTHOR]
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- 2021
- Full Text
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27. An alternative Z-score measure for downside bank insolvency risk.
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Lepetit, Laetitia, Strobel, Frank, and Tran, Thu Ha
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BANKRUPTCY ,BANKING industry ,RISK ,MATHEMATICAL equivalence - Abstract
We derive a Z-score measure reflecting downside bank insolvency risk, drawing on a Chebyshev inequality in terms of the lower semivariance. As then illustrated empirically for US banks, this may provide a useful alternative, or robustness check, to the more commonly used Z-score measure based on the standard Chebyshev inequality. [ABSTRACT FROM AUTHOR]
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- 2021
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28. A universal method for rapid and large‐scale growth of layered crystals.
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Chaturvedi, Apoorva, Chen, Bo, Zhang, Keke, He, Qiyuan, Nam, Gwang‐Hyeon, You, Lu, Lai, Zhuangchai, Tan, Chaoliang, Tran, Thu Ha, Liu, Guigao, Zhou, Jiadong, Liu, Zheng, Wang, Junling, Teo, Edwin H. T., and Zhang, Hua
- Abstract
Layered van der Waals (vdW) materials, consisting of atomically thin layers, are of paramount importance in physics, chemistry, and materials science owing to their unique properties and various promising applications. However, their fast and large‐scale growth via a general approach is still a big challenge, severely limiting their practical implementations. Here, we report a universal method for rapid (~60 min) and large‐scale (gram scale) growth of phase‐pure, high‐crystalline layered vdW materials from their elementary powders via microwave plasma heating in sealed ampoules. This method can be used for growth of 30 compounds with different components (binary, ternary, and quaternary) and properties. The ferroelectric and transport properties of mechanically exfoliated flakes validate the high crystal quality of the grown materials. Our study provides a general strategy for the fast and large‐scale growth of layered vdW materials with appealing physiochemical properties, which could be used for various promising applications. [ABSTRACT FROM AUTHOR]
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- 2020
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29. Effect of low-dose versus higher-dose antenatal iron supplementation on child health outcomes at 36 months of age in Viet Nam: longitudinal follow-up of a cluster randomised controlled trial
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Beverley-Ann Biggs, Sarah Hanieh, Janet C. King, Tran Thu Ha, Julie A. Simpson, Jane Fisher, Tran Thi Thuy, Sabine Braat, Thach Duc Tran, and Tran Tuan
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0301 basic medicine ,Pediatrics ,medicine.medical_specialty ,Disease cluster ,Bayley Scales of Infant Development ,03 medical and health sciences ,0302 clinical medicine ,medicine ,030212 general & internal medicine ,Cluster randomised controlled trial ,Toddler ,Prospective cohort study ,Pregnancy ,030109 nutrition & dietetics ,business.industry ,Health Policy ,Research ,public health ,Public Health, Environmental and Occupational Health ,medicine.disease ,Micronutrient ,3. Good health ,Clinical trial ,nutrition ,child health ,Maternal health ,business - Abstract
Introduction Intermittent iron-folic acid supplementation (IFA) is currently recommended for pregnant women in populations where anaemia prevalence among pregnant women is
- Published
- 2017
30. A Calculation of Energy Consumption for Residential Air Conditioners using Bin Method in the Vietnamese Climatic Conditions.
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Trinh, Quoc Dung, Vu, Tuan Anh, Nguyen, Viet Dzung, Pham, Hoang Luong, and Tran, Thu Ha Thi
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- 2020
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31. Controllable growth of Au nanostructures onto MoS2 nanosheets for dual-modal imaging and photothermal–radiation combined therapy.
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Liu, Teng, Shen, Sida, Huang, Ying, Zhang, Xiao, Lai, Zhuangchai, Tran, Thu Ha, Liu, Zhuang, and Cheng, Liang
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- 2019
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32. Evaluation of the psychometric properties of the Self-Reporting Questionnaire (SRQ-20) in a sample of Vietnamese adults
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Tran Thu Ha, Tran Duc Thach, Steven H. Aggen, Ron Acierno, Nguyen Thanh Tam, Lam Tu Trung, Kelcey J. Stratton, Dean G. Kilpatrick, Tran Tuan, Mario T. Gaboury, La Thi Buoi, Trinh Luong Tran, Lisa K. Richardson, and Ananda B. Amstadter
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Adult ,Male ,Psychometrics ,lcsh:RC435-571 ,Vietnamese ,Mental distress ,Sex Factors ,Surveys and Questionnaires ,lcsh:Psychiatry ,Prevalence ,Humans ,Latent variable model ,Aged ,Aged, 80 and over ,Mental Disorders ,Age Factors ,Middle Aged ,Mental health ,language.human_language ,Confirmatory factor analysis ,Exploratory factor analysis ,Psychiatry and Mental health ,Clinical Psychology ,Distress ,Vietnam ,Needs assessment ,language ,Female ,Self Report ,Factor Analysis, Statistical ,Psychology ,Needs Assessment ,Clinical psychology - Abstract
Purpose There are significant gaps in the literature on the prevalence of mental health problems and associated needs in Vietnam. A thorough understanding of culture-specific expressions of psychiatric distress is vital for the identification of the mental health needs of a community, and more research on the development and evaluation of culturally-sensitive mental health assessments is warranted. This study aims to evaluate the psychometric properties of the World Health Organization 20-item Self-Reporting Questionnaire (SRQ-20) in an epidemiologic study of Vietnamese adults. Methods A latent variable modeling approach investigated the underlying factor structure of the SRQ-20 items. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were conducted on SRQ-20 item-level data gathered from 4980 participants. Results Based on scree plots and EFA results, two latent structures were deemed plausible and were subsequently subjected to further modeling. A bi-factor model (BFM) and a correlated three-factor model solution (Negative Affect, Somatic Complaints, and Hopelessness) provided reasonable fits. The BFM specifies a single dominant General Distress factor (all SRQ-20 items) with orthogonal group factors for the subsets of items: Negative Affect (9 items), Somatic Complaints (8 items), and Hopelessness (3 items). This model fit the data as well or better than the three-factor model. Results also showed differences in endorsement rates of SRQ-20 items among males and females. Conclusions Study results provide an evaluation of the psychometric properties of a commonly used screening tool and offer insight into the presentation of mental distress in a representative sample of Vietnamese adults.
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- 2013
33. Maternal Vitamin D Status and Infant Outcomes in Rural Vietnam: A Prospective Cohort Study
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Jane Fisher, Beverley-Ann Biggs, Sarah Hanieh, Tran Tuan, Dang Dinh Thoang, Julie A. Simpson, Tran Thi Thuy, Nguyen Khuong, Thach Duc Tran, and Tran Thu Ha
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Adult ,Male ,Rural Population ,Pediatrics ,medicine.medical_specialty ,030309 nutrition & dietetics ,Birth weight ,lcsh:Medicine ,030209 endocrinology & metabolism ,Global Health ,Bayley Scales of Infant Development ,vitamin D deficiency ,03 medical and health sciences ,0302 clinical medicine ,Child Development ,Pregnancy ,Vitamin D and neurology ,medicine ,Medicine and Health Sciences ,Humans ,Public and Occupational Health ,Vitamin D ,Prospective cohort study ,lcsh:Science ,Nutrition ,2. Zero hunger ,25-Hydroxyvitamin D 2 ,0303 health sciences ,Multidisciplinary ,business.industry ,lcsh:R ,Child Health ,Infant, Newborn ,Biology and Life Sciences ,Nutrients ,Vitamins ,medicine.disease ,Micronutrient ,Vitamin D Deficiency ,3. Good health ,Vietnam ,Dietary Supplements ,Gestation ,lcsh:Q ,Female ,business ,Research Article - Abstract
Objective Vitamin D deficiency affects 1 billion people globally. It has an important role in bone homeostasis, brain development and modulation of the immune system and yet the impact of antenatal vitamin D deficiency on infant outcomes is poorly understood. We assessed the association of 25- hydroxyvitamin D levels (25-OHD) in late pregnancy and early infant growth and developmental outcomes in rural Vietnam. Design and Methods A prospective cohort study of 960 women who had previously participated in a double-blind cluster randomized controlled trial of antenatal micronutrient supplementation in rural Vietnam was undertaken. Maternal 25-OHD concentration was measured at 32 weeks gestation, and infants were followed until 6 months of age. Main outcome measures were cognitive, motor, socio-emotional and language scores using the Bayley Scales of Infant Development, 3rd edition, and infant length-for-age z scores at 6 months of age. Results 60% (582/960) of women had 25-OHD levels
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- 2014
34. Using the SRQ–20 Factor Structure to Examine Changes in Mental Distress Following Typhoon Exposure
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Tran Thu Ha, Trinh Luong Tran, Lam Tu Trung, Tran Duc Thach, Steven H. Aggen, Ananda B. Amstadter, Tran Tuan, La Thi Buoi, Kelcey J. Stratton, Lisa K. Richardson, Erin C. Berenz, and Nguyen Thanh Tam
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Adult ,Male ,Poison control ,Occupational safety and health ,Article ,Disasters ,Mental distress ,Sex Factors ,Surveys and Questionnaires ,Injury prevention ,Cluster Analysis ,Humans ,Cyclonic Storms ,Mental Disorders ,Age Factors ,Human factors and ergonomics ,Personal injury ,Mental health ,Psychiatry and Mental health ,Clinical Psychology ,Distress ,Vietnam ,Female ,Self Report ,Psychology ,Factor Analysis, Statistical ,Social psychology ,Clinical psychology - Abstract
Empirical research is limited regarding postdisaster assessment of distress in developing nations. This study aimed to evaluate the factor structure of the 20-item Self-Reporting Questionnaire (SRQ-20) before and after an acute trauma, Typhoon Xangsane, in order to examine changes in mental health symptoms in an epidemiologic sample of Vietnamese adults. The study examined a model estimating individual item factor loadings, thresholds, and a latent change factor for the SRQ-20's single "general distress" common factor. The covariates of sex, age, and severity of typhoon exposure were used to evaluate the disaster-induced changes in SRQ-20 scores while accounting for possible differences in the relationship between individual measurement scale items and the latent mental health construct. Evidence for measurement noninvariance was found. However, allowing sex and age effects on the pre-typhoon and post-typhoon factors accounted for much of the noninvariance in the SRQ-20 measurement structure. A test of no latent change failed, indicating that the SRQ-20 detected significant individual differences in distress between pre- and post-typhoon assessment. Conditioning on age and sex, several typhoon exposure variables differentially predicted levels of distress change, including evacuation, personal injury, and peri-event fear. On average, females and older individuals reported higher levels of distress than males and younger individuals, respectively. The SRQ-20 is a valid and reasonably stable instrument that may be used in postdisaster contexts to assess emotional distress and individual changes in mental health symptoms.
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- 2014
35. On some problems of sediment transport in rivers
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LICHT, Christian, Tran Thu, Ha, Laboratoire de Mécanique et Génie Civil (LMGC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Modélisation Mathématique en Mécanique (M3), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), and Hanoi University of Science and Technology (HUST)
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ComputingMilieux_MISCELLANEOUS ,[SPI.MECA.MEFL]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Fluids mechanics [physics.class-ph] - Abstract
International audience
- Published
- 2013
36. The Effect of Intermittent Antenatal Iron Supplementation on Maternal and Infant Outcomes in Rural Viet Nam: A Cluster Randomised Trial
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Nguyen Khuong, Tran Thi Thuy, Thach Duc Tran, Sant-Rayn Pasricha, Dang Dinh Thoang, Tran Thu Ha, Sarah Hanieh, Jane Fisher, Gerard J. Casey, Tran Tuan, Terence Dwyer, Julie A. Simpson, and Beverley-Ann Biggs
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Rural Population ,Pediatrics ,030309 nutrition & dietetics ,lcsh:Medicine ,law.invention ,Hemoglobins ,0302 clinical medicine ,Child Development ,Randomized controlled trial ,law ,Pregnancy ,Odds Ratio ,030212 general & internal medicine ,Micronutrients ,2. Zero hunger ,0303 health sciences ,education.field_of_study ,Pregnancy Outcome ,Obstetrics and Gynecology ,General Medicine ,Micronutrient ,3. Good health ,Treatment Outcome ,Vietnam ,Gestation ,Medicine ,Female ,Public Health ,Growth and Development ,Research Article ,Tablets ,Adult ,medicine.medical_specialty ,Anemia ,Birth weight ,Iron ,Population ,Capsules ,Medication Adherence ,03 medical and health sciences ,Young Adult ,parasitic diseases ,medicine ,Humans ,education ,Nutrition ,business.industry ,lcsh:R ,Infant, Newborn ,Infant ,medicine.disease ,bacterial infections and mycoses ,Iron-deficiency anemia ,Dietary Supplements ,business - Abstract
Beverley-Anne Biggs and colleagues conduct a community-based cluster randomized trial in rural Viet Nam to compare the effect of antenatal iron-folic acid supplementation taken daily or twice weekly on maternal and infant outcomes. Please see later in the article for the Editors' Summary, Background Anemia affects over 500 million women, and in pregnancy is associated with impaired maternal and infant outcomes. Intermittent antenatal iron supplementation is an attractive alternative to daily dosing; however, the impact of this strategy on infant outcomes remains unclear. We compared the effect of intermittent antenatal iron supplementation with daily iron supplementation on maternal and infant outcomes in rural Viet Nam. Methods and Findings This cluster randomised trial was conducted in Ha Nam province, Viet Nam. 1,258 pregnant women (, Editors' Summary Background Anemia is a common condition in which the blood does not supply the body with enough oxygen because of a low number of red blood cells or low levels of hemoglobin—the iron-containing pigment that enables red blood cells to carry oxygen. Iron deficiency is the most common cause of anemia worldwide and, according to the World Health Organization, affects over 2 billion people: half of all pregnant women and 40% of preschool children in low- and middle-income countries are thought to be anemic. Anemia contributes to 20% of all maternal deaths and is also linked to increased maternal morbidity, higher rates of preterm birth and low birth weight, and reduced infant survival, with potential long-term consequences for child growth and development. Identifying and treating iron deficiency anemia is therefore a global health priority. Why Was This Study Done? Daily iron–folic acid supplementation given from early in pregnancy is the standard recommended approach to prevent and treat anemia in pregnant women, but recently the World Health Organization recommended intermittent use because of poor compliance with daily regimes (because of side effects) and poor bowel absorption. However, the evidence from many of the studies used to support this recommendation was of poor quality, and so it remains unclear whether intermittent supplementation is as, or more, effective than daily supplementation, especially in lower income settings where antenatal testing for anemia is not readily available. So in this study, the researchers conducted a community-based cluster randomized trial (where groups of people are randomized, rather than individuals) in rural Viet Nam to compare the effect of antenatal iron–folic acid supplementation taken twice weekly (either alone, or in combination with other micronutrients) with daily iron–folic acid supplementation, on maternal and infant outcomes during the first six months of life. What Did the Researchers Do and Find? The researchers randomized 104 communes in Ha Nam Province, Viet Nam, and enrolled 1,258 women who were less than 16 weeks pregnant into the study between September and November 2010. Although the researchers intended to register the trial before the study started, registration was delayed by a month because the supplements arrived earlier than the researchers anticipated, and they thought it best to start recruiting at that time to avoid the Vietnamese New Year, when women might be travelling. Each woman was interviewed and had blood taken for hemoglobin and iron indices (ferritin) before receiving daily iron–folic acid supplementation (426 women), twice weekly iron–folic acid supplementation (425 women), or twice weekly iron–folic acid supplementation plus micronutrients (407 women). The women had follow-up assessments at 32 weeks gestation, delivery, and at six months postpartum: their infants were assessed at birth and at six months old. The researchers found that at enrollment, the women's average hemoglobin concentration was 123 g/l, and 12.6% of the women were anemic. At 32 weeks gestation, 10.8% of the women were anemic, but there was no difference in hemoglobin levels between the three supplement groups. The average ferritin level was 75.6 µg/l at enrollment, with 2.2% of women iron deficient. Ferritin levels decreased from enrollment to 32 weeks gestation in all supplement groups but were lower in women who took twice weekly supplements. The researchers also found that birth weight (the primary outcome) was similar in all supplement groups, and there were also no differences in gestational age or in the risk of prematurity, stillbirth, or early neonatal death. At six months, there were also no differences in the levels of infant hemoglobin, prevalence of anemia, or growth rates. However, infants born to mothers in the twice weekly iron–folic acid group had improved cognitive development compared to infants born to mothers in the daily supplement group. Finally, the researchers found that adherence rates were significantly higher in the twice weekly iron–folic acid supplement group compared to the once daily regime. What Do These Findings Mean? These findings suggest that in an area of Southeast Asia with low anemia prevalence, once daily antenatal supplementation with iron–folic acid did not provide any benefits in birth weight or improved infant growth over twice weekly supplementation. Furthermore, twice weekly supplementation with iron–folic acid was associated with improved maternal adherence rates and also improved cognitive development in infants aged six months—a finding that requires further study and provides added support for the use of intermittent iron–folic acid supplementation over daily supplementation. Additional Information Please access these websites via the online version of this summary at http://dx.doi.org/10.1371/journal.pmed.1001470. The World Health Organization website has comprehensive information on anemia, including a report of global estimates and the guideline Intermittent Iron and Folic Acid Supplementation in Non-Anaemic Pregnant Women Wikipedia provides information on iron supplementation (note: Wikipedia is a free online encyclopedia that anyone can edit; available in several languages)
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- 2013
37. Preparation of 1T′-Phase ReS2xSe2(1‑x) (x = 0–1) Nanodots for Highly Efficient Electrocatalytic Hydrogen Evolution Reaction.
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Lai, Zhuangchai, Chaturvedi, Apoorva, Wang, Yun, Tran, Thu Ha, Liu, Xiaozhi, Tan, Chaoliang, Luo, Zhimin, Chen, Bo, Huang, Ying, Nam, Gwang-Hyeon, Zhang, Zhicheng, Chen, Ye, Hu, Zhaoning, Li, Bing, Xi, Shibo, Zhang, Qinghua, Zong, Yun, Gu, Lin, Kloc, Christian, and Du, Yonghua
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- 2018
- Full Text
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38. The Water Pollution Problem and application of data assimilation methods
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Tran Thu, Ha, Le Dimet, François-Xavier, Institute of Mechanics [Hanoi], Vietnam Academy of Science and Technology (VAST), Modelling, Observations, Identification for Environmental Sciences (MOISE), Inria Grenoble - Rhône-Alpes, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire Jean Kuntzmann (LJK), and Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)
- Subjects
[MATH.MATH-OC]Mathematics [math]/Optimization and Control [math.OC] ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2012
39. The conversion coefficient of water pollution
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Tran Thu, Ha, Le Dimet, François-Xavier, Hoang Van, Lai, Nguyen Ba, Hung, Institute of Mechanics [Hanoi], Vietnam Academy of Science and Technology (VAST), Modelling, Observations, Identification for Environmental Sciences (MOISE), Inria Grenoble - Rhône-Alpes, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire Jean Kuntzmann (LJK), and Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Pierre Mendès France - Grenoble 2 (UPMF)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)
- Subjects
[MATH.MATH-OC]Mathematics [math]/Optimization and Control [math.OC] ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
- Published
- 2012
40. General sensitivity analysis in data assimilation.
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Le Dimet, Francois-Xavier, Shutyaev, Victor P., and Tran, Thu Ha
- Subjects
DATA analysis ,SENSITIVITY analysis ,NONLINEAR evolution equations ,PARAMETER estimation ,NUMERICAL analysis ,HYDRAULICS - Abstract
The problem of variational data assimilation for a nonlinear evolution model is formulated as an optimal control problem to find the initial condition function (analysis). The operator of the model, and hence the optimal solution, depend on the parameters which may contain uncertainties. A response function is considered as a functional of the solution after assimilation. Based on the second-order adjoint techniques, the sensitivity of the response function to the parameters of the model is studied. The gradient of the response function is related to the solution of a non-standard problem involving the coupled system of direct and adjoint equations. The solvability of the non-standard problem is studied. Numerical algorithms for solving the problem are developed. The results are applied for 2D hydraulic and pollution models. Numerical examples on computation of the gradient of the response function are presented. [ABSTRACT FROM AUTHOR]
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- 2014
- Full Text
- View/download PDF
41. UPDATE: A Pre-/Post-Disaster Epidemiological Study of Mental Health Functioning in Vietnam's DaNang Province following Typhoon Xangsane.
- Author
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WILLIAMS, JOAH, ACIERNO, RON, GROS, DANIEL F., AMSTADTER, ANANDA B., TRINH LUONG TRAN, LAM TU TRUNG, NGUYEN THANH TAM, TRAN TUAN, LA THI BUOI, TRAN THU HA, and TRAN DUC THACH
- Subjects
NATURAL disasters & psychology ,PSYCHOLOGY of disaster victims ,MENTAL health services - Abstract
In 2006, typhoon Xangsane struck Vietnam and disrupted a large-scale mental health needs analysis in the DaNang province of Vietnam in the active recruitment phase. Following the typhoon, the design of study was altered to that of a pre-/post-event investigation, in which 798 of the original 4,982 participants were re-interviewed so that risk and protective factors could be evaluated with respect to probable mental health "caseness" on the basis of the World Health Organization Short Response Questionnaire (SRQ-20) 7/8 cutoff (i.e., scores of 8 or more). Results indicated that caseness prevalence was 20.7% pre-disaster and 27.1% post-disaster. Specific risk factors associated with post-disaster mental health caseness included poor health, extreme peri-disaster fear, and experienced injury. Religious affiliation appeared to be a protective factor. In contrast to US and Asian samples, gender was not predictive of outcome. [ABSTRACT FROM AUTHOR]
- Published
- 2014
42. Evaluation of the psychometric properties of the Self-Reporting Questionnaire (SRQ-20) in a sample of Vietnamese adults.
- Author
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Stratton, Kelcey J., Aggen, Steven H., Richardson, Lisa K., Acierno, Ron, Kilpatrick, Dean G., Gaboury, Mario T., Trinh Luong Tran, Lam Tu Trung, Nguyen Thanh Tami, Tran Tuan, La Thi Buoi, Tran Thu Ha, Tran Duc Thach, and Amstadter, Ananda B.
- Abstract
Purpose: There are significant gaps in the literature on the prevalence of mental health problems and associated needs in Vietnam. A thorough understanding of culture-specific expressions of psychiatric distress is vital for the identification of the mental health needs of a community, and more research on the development and evaluation of culturally-sensitive mental health assessments is warranted. This study aims to evaluate the psychometric properties of the World Health Organization 20-item Self-Reporting Questionnaire (SRQ-20) in an epidemiologic study of Vietnamese adults. Methods: A latent variable modeling approach investigated the underlying factor structure of the SRQ-20 items. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were conducted on SRQ-20 item-level data gathered from 4980 participants. Results: Based on scree plots and EFA results, two latent structures were deemed plausible and were subsequently subjected to further modeling. A bi-factor model (BFM) and a correlated three-factor model solution (Negative Affect, Somatic Complaints, and Hopelessness) provided reasonable fits. The BFM specifies a single dominant General Distress factor (all SRQ-20 items) with orthogonal group factors for the subsets of items: Negative Affect (9 items), Somatic Complaints (8 items), and Hopelessness (3 items). This model fit the data as well or better than the three-factor model. Results also showed differences in endorsement rates of SRQ-20 items among males and females. Conclusions: Study results provide an evaluation of the psychometric properties of a commonly used screening tool and offer insight into the presentation of mental distress in a representative sample of Vietnamese adults. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
43. Mental Health Correlates of Post Disaster Increases in Alcohol and Cigarette Smoking: A Vietnamese Study.
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Ritter, Juliana D., McCauley, Jenna L., Amstadter, Ananda B., Richardson, Lisa, Kilpatrick, Dean, Tran, Trinh L., Trung, Lam T., Tam, Nguyen T., Tuan, Tran, La Thi Buoi, Tran Thu Ha, Thach, Tran D., and Acierno, Ron
- Subjects
PSYCHOLOGY of alcoholism ,SMOKING & psychology ,TYPHOONS ,ANXIETY disorders ,MENTAL health ,PSYCHOLOGY - Abstract
Previous research in US populations has found associations between disaster-related variables, psychological variables, and post-disaster increases in smoking and alcohol use. To date, no research has examined this association in an international population of disaster exposed individuals. Data used in this study were drawn from a larger study involving a two-wave assessment of a disaster-affected sample of Vietnamese citizens ( N = 798). Interviews were conducted to assess the effects of mental health variables and typhoon related variables on reported increases in alcohol use and cigarette smoking. Results indicate that post-disaster increases in smoking were associated with post-disaster diagnosis of generalized anxiety disorder. Post-disaster increases in alcohol use were associated with posttraumatic stress disorder and panic disorder. None of the typhoon-characteristics were significantly associated with increases in substance use. Implications for mental health providers and future research directions are discussed. [ABSTRACT FROM AUTHOR]
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- 2011
- Full Text
- View/download PDF
44. Does Interviewer Status Matter? An Examination of Lay Interviewers and Medical Doctor Interviewers in an Epidemiological Study in Vietnam.
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Amstadter, Ananda B., Richardson, Lisa, Acierno, Ron, Kilpatrick, Dean G., Trinh Luong Tran, Nguyen Thanh Tam, Gaboury, Mario T., Lam Tu Trung, Tran Tuan, La Thi Buoi, Tran Thu Ha, and Tran Duc Thach
- Subjects
INTERVIEWERS ,EPIDEMIOLOGICAL research ,POST-traumatic stress disorder ,MENTAL depression ,PANIC disorders ,ANXIETY - Abstract
In 2006, Typhoon Xangsane disrupted a large-scale multi-agency mental health study of 4,981 individuals in the Da Nang province of Vietnam. Following this disaster, 795 of the original 4,981 participants were randomly assigned to be re-interviewed by either a medical doctor or a lay interviewer using structured clinical interviews to determine the prevalence of lifetime and post-typhoon post-traumatic stress disorder (PTSD), major depressive disorder (MDD), panic disorder (PD), and generalized anxiety disorder (GAD) according to the Diagnostic and Statistical Manual of Mental Disorders (4th edition; American Psychiatric Association, 1994). The aim of the present study was to determine if the prevalence of disorders differed by interviewer type. Bivariate analyses and multivariable analyses, as well as internal reliability estimates, all indicated no significant differences between the medical doctor interviewers versus the lay interviewers. This held for both lifetime prevalence and post-typhoon prevalence of disorders. This study has implications for epidemiologic studies, as it indicates that with adequate training, the use of lay interviewers may be a valid means of data collection. [ABSTRACT FROM AUTHOR]
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- 2010
- Full Text
- View/download PDF
45. ESTIMATING MENTAL DISTRESS IN VIETNAM: THE USE OF THE SRQ-20.
- Author
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Richardson, Lisa K., Amstadter, Ananda B., Kilpatrick, Dean G., Gaboury, Mario T., Trinh Luong Tran, Lam Tu Trung, Nguyen Thanh Tam, Tran Tuan, La Thi Buoi, Tran Thu Ha, Tran Duc Thach, and Acierno, Ron
- Subjects
PSYCHIATRIC research ,PSYCHOLOGICAL distress ,MENTAL health ,PATHOLOGICAL psychology ,DEVELOPING countries - Abstract
Background: Community-based estimates of psychopathology prevalence in developing countries such as Vietnam, are needed to reduce presumed significant burden of poor mental health. Aims: This study derived population-based prevalence estimates of mental distress, as measured by the SRQ-20, in a community sample of 4,981 adults living in Vietnam. This study also examined correlates of mental distress based on SRQ-20 caseness indications. Risk and protective factors were identified in terms of their unique contribution to caseness. Results: Using a cut-off of 7/8, 19.2% of the sample was considered to be a probable case (n = 954), with females endorsing more items than males. Marital status and employment status were not associated with mental health distress. Higher wealth, endorsing religious affiliation, and self-reports of good health were associated with lower SRQ-20 scores. Age and being female were associated with higher SRQ-20 scores. Conclusions: A single item was as adequate a measure of wealth as multi-item rating scales. Our estimate of mental distress using the SRQ-20 is much greater than that of other studies, and in contrast to western prevalence studies, age was not a protective factor in this study. The SRQ-20 is a brief, cost-effective and reasonably valid measure of both community and individual mental distress. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF
46. A Pre-/Post-Disaster Epidemiological Study of Mental Health Functioning in Vietnam's Da Nang Province Following Typhoon Xangsane.
- Author
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ACIERNO, RON, AMSTADTER, ANANDA B., GROS, DANIEL F., RICHARDSON, LISA, KILPATRICK, DEAN G., LAMTUTRUNG, TRAN TUAN, LA THI BUOI, TRAN THU HA, TRAN DUC THACH, GABOURY, MARIO T., TRINH LUONG TRAN, NGUYEN THANH TAM, SEYMOUR, ANNE, and GALEA, SANDRO
- Published
- 2009
47. Graptopetalum paraguayense Extract Ameliorates Proteotoxicity in Aging and Age-Related Diseases in Model Systems.
- Author
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Chen, Yan-Xi, Le, Phuong Thu Nguyen, Tzeng, Tsai-Teng, Tran, Thu-Ha, Nguyen, Anh Thuc, Cheng, Irene Han-Juo, Huang, Chi-Ying F., Shiao, Young-Ji, and Ching, Tsui-Ting
- Abstract
Declines in physiological functions are the predominant risk factors for age-related diseases, such as cancers and neurodegenerative diseases. Therefore, delaying the aging process is believed to be beneficial in preventing the onset of age-related diseases. Previous studies have demonstrated that Graptopetalum paraguayense (GP) extract inhibits liver cancer cell growth and reduces the pathological phenotypes of Alzheimer's disease (AD) in patient IPS-derived neurons. Here, we show that GP extract suppresses β-amyloid pathology in SH-SYS5Y-APP
695 cells and APP/PS1 mice. Moreover, AMP-activated protein kinase (AMPK) activity is enhanced by GP extract in U87 cells and APP/PS1 mice. Intriguingly, GP extract enhances autophagy in SH-SYS5Y-APP695 cells, U87 cells, and the nematode Caenorhabditis elegans, suggesting a conserved molecular mechanism by which GP extract might regulate autophagy. In agreement with its role as an autophagy activator, GP extract markedly diminishes mobility decline in polyglutamine Q35 mutants and aged wild-type N2 animals in C. elegans. Furthermore, GP extract significantly extends lifespan in C. elegans. [ABSTRACT FROM AUTHOR]- Published
- 2021
- Full Text
- View/download PDF
48. Accuracy of child growth-monitoring weights obtained by commune volunteers in Phu Tho Province, Vietnam.
- Author
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Van Thuy Huong, Tran Duc Thach, Tran Tuan, Tran Thu Ha, and Marsh, David R.
- Abstract
Background. Weight-for-age is a commonly used indicator of the health of children and communities. We determined the accuracy of health volunteers' weight measurements in a nutrition project in Vietnam. Objective. To report the accuracy of the volunteers' weight measurements and to assess the likely effect of any inaccuracies. Methods. Save the Children /USA trained health volunteers to weigh children (6--36 months old) every other month from December 1999 to August 2000. Trained researchers randomly rechecked 257 weights (range, 24--114 per session). We computed nondirectional and directional differences between the weights measured by volunteers and those measured by researchers. Results. The weights recorded by volunteers were lower than those recorded by researchers by an average of 30 g (p < .05). Almost all of the error occurred during the first weighing session, at which the average weight recorded by volunteers was 280 g below that recorded by researchers (p = .01). The error at subsequent weighings was minimal (< 20 g below reference at each session). Conclusions. One-time directional error suggests bias. Perhaps some communities (or families) influenced the volunteers to report weights lower than those actually observed to justify the programmatic food supplements or to give the impression at subsequent weighings that the level of malnutrition had been successfully reduced from that at the first session. Careful supervision of measurements of weight at baseline is essential. [ABSTRACT FROM AUTHOR]
- Published
- 2006
- Full Text
- View/download PDF
49. Identification of Withaferin A as a Potential Candidate for Anti-Cancer Therapy in Non-Small Cell Lung Cancer.
- Author
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Hsu, Jade H.-M., Chang, Peter M.-H., Cheng, Tai-Shan, Kuo, Yu-Lun, Wu, Alexander T.-H., Tran, Thu-Ha, Yang, Yun-Hsuan, Chen, Jing-Ming, Tsai, Yu-Chen, Chu, Yeh-Shiu, Huang, Tse- Hung, Huang, Chi-Ying F., and Lai, Jin-Mei
- Subjects
AUTOPHAGY ,REACTIVE oxygen species ,ANIMAL experimentation ,APOPTOSIS ,CANCER chemotherapy ,CARRIER proteins ,CELL lines ,CELLULAR signal transduction ,COMBINATION drug therapy ,CISPLATIN ,DRUG resistance in cancer cells ,CLINICAL drug trials ,EPIDERMAL growth factor ,LUNG cancer ,MEDICINAL plants ,MICE ,PROTEIN kinases ,PROTEINS ,STEROIDS ,PLANT extracts ,CELL survival ,PEMETREXED ,IN vivo studies ,PHARMACODYNAMICS - Abstract
Low response rate and recurrence are common issues in lung cancer; thus, identifying a potential compound for these patients is essential. Utilizing an in silico screening method, we identified withaferin A (WA), a cell-permeable steroidal lactone initially extracted from Withania somnifera, as a potential anti–lung cancer and anti–lung cancer stem-like cell (CSC) agent. First, we demonstrated that WA exhibited potent cytotoxicity in several lung cancer cells, as evidenced by low IC
50 values. WA concurrently induced autophagy and apoptosis and the activation of reactive oxygen species (ROS), which plays an upstream role in mediating WA-elicited effects. The increase in p62 indicated that WA may modulate the autophagy flux followed by apoptosis. In vivo research also demonstrated the anti-tumor effect of WA treatment. We subsequently demonstrated that WA could inhibit the growth of lung CSCs, decrease side population cells, and inhibit lung cancer spheroid-forming capacity, at least through downregulation of mTOR/STAT3 signaling. Furthermore, the combination of WA and chemotherapeutic drugs, including cisplatin and pemetrexed, exerted synergistic effects on the inhibition of epidermal growth factor receptor (EGFR) wild-type lung cancer cell viability. In addition, WA can further enhance the cytotoxic effect of cisplatin in lung CSCs. Therefore, WA alone or in combination with standard chemotherapy is a potential treatment option for EGFR wild-type lung cancer and may decrease the occurrence of cisplatin resistance by inhibiting lung CSCs. [ABSTRACT FROM AUTHOR]- Published
- 2019
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50. Postnatal growth outcomes and influence of maternal gestational weight gain: a prospective cohort study in rural Vietnam
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Jane Fisher, Tran Tuan, Dang Dinh Thoang, Tran Thu Ha, Julie A. Simpson, Nguyen Khuong, Tran Thi Thuy, Beverley-Ann Biggs, Sarah Hanieh, and Thach Duc Tran
- Subjects
Adult ,Rural Population ,Pediatrics ,medicine.medical_specialty ,Birth weight ,Gestational weight gain ,Weight Gain ,Body Mass Index ,Young Adult ,Child Development ,Pregnancy ,Weight for Age ,Obstetrics and Gynaecology ,medicine ,Birth Weight ,Humans ,Prospective Studies ,Occupations ,Prospective cohort study ,Postnatal growth ,business.industry ,Infant, Newborn ,Infant ,Obstetrics and Gynecology ,medicine.disease ,Body Height ,Gestational diabetes ,Low birth weight ,Vietnam ,Dietary Supplements ,Educational Status ,Female ,medicine.symptom ,business ,Weight gain ,Body mass index ,Research Article - Abstract
Background Suboptimal weight gain during pregnancy may result in adverse outcomes for both the mother and child, including increased risk of pre-eclampsia and gestational diabetes, delivery of low birth weight and small-for-gestational age (SGA) infants, and preterm delivery. The objectives of this study were to identify maternal predictors of rate of weight gain in pregnancy, and to evaluate the association of gestational weight gain with infant postnatal growth outcomes. Methods We conducted a prospective cohort study of infants born to women who had previously participated in a double-blind cluster randomized controlled trial of antenatal micronutrient supplementation, in Ha Nam province, Vietnam. Pregnant women (n = 1258) were seen at enrolment and 32 weeks gestation, and infants (n = 965) were followed until 6 months of age. Primary outcome was infant anthropometric indicators at 6 months of age (weight for age, length for age, weight for height z scores), and infant weight gain velocity during the first 6 months of life. Results Low body mass index (
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