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1. Neurocritical Patients: Review of the Scope of Nursing Diagnoses and Care in the Intensive Care Unit

Author

Maria Luiza Peixoto Brito, Luis Fernando Reis Macedo, Kenya Waléria de Siqueira Coelho Lisboa, Valterlúcio dos Santos Sales, Sarah de Lima Pinto, and Darly Suyane Felix Silva

Subjects
Nursing, RT1-120
Abstract

Objective To identify the diagnoses and nursing care for neurocritical patients in the intensive care unit. Method This is a scope review study, based on the Joanna Briggs Institute, led by the following guiding question: what are the diagnoses and nursing care for neurocritical patients in the intensive care unit? Data collection was carried out in February 2022 in a paired manner, in the following databases: EMBASE, MEDLINE, PubMed, and SCOPUS. For sample selection, the following search strategy was used: “Neurology” AND “Nursing Care” OR “Nursing Diagnosis” AND “Critical Care.” Studies were independently selected, blinded by two reviewers. Result It was possible to identify 854 studies, which after analysis by title and abstract, only 27 articles passed the eligibility, of which 10 were part of this review. Conclusion According to the analysis of the studies, it was found that nursing care, combined with a care plan for neurocritical patients, allows for better results, with a view to the quality of life and health promotion.

Published
2023
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2. Antiulcerogenic activity of the hydroalcoholic extract of leaves of Annona muricata Linnaeus in mice

Author

Valterlúcio dos Santos Sales, Álefe Brito Monteiro, Izabel Cristina Santiago Lemos, Gyllyandeson de Araújo Delmondes, Francisco Elizaudo de Brito Junior, Elizângela B. Bento, José Galberto Martins da Costa, Marta Regina Kerntopf, C. K. Rodrigues, Dayanne Rakelly de Oliveira, Francisco Rafael Alves Santana Cesário, Irwin Rose Alencar de Menezes, Francisco Rodolpho Sobreira Dantas Nóbrega de Figuêiredo, and Cícera Norma Fernandes

Subjects
0301 basic medicine, Pharmacology, 01 natural sciences, Annona, Nitric oxide, law.invention, 03 medical and health sciences, chemistry.chemical_compound, Medicinal plants, law, medicine, lcsh:QH301-705.5, Annona muricata, Ethanol, Peptic ulcer, biology, Agricultural and Biological Sciences(all), biology.organism_classification, Antispasmodic Agent, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, lcsh:Biology (General), chemistry, Mechanism of action, medicine.symptom, General Agricultural and Biological Sciences, Phytotherapy
Abstract

Annona muricata Linnaeus, popularly known as “graviola” and also called soursop, is a species typical of countries with a tropical climate, and it is used in folk medicine as an anticancer, analgesic and antispasmodic agent. The aim of the present study was to validate the gastroprotective activity of the hydroalcoholic extract of the leaves of A. muricata (HEAM) and to investigate the underlying mechanisms of action for this effect. Gastric lesions were induced in mice by absolute ethanol, acidified ethanol or indomethacin. Before, the animals were pretreated with saline, omeprazole or HEAM orally at doses of 50–400 mg/kg. To determine the mechanism of action of the extract, we investigated, using specific inhibitors, the involvement of nitric oxide (NO), prostaglandins (PGEs), ATP-dependent K+ channels and α2-noradrenergic receptors. HEAM showed significant antiulcer activity against lesions induced by absolute ethanol, acidified ethanol or indomethacin, which was mediated by endogenous gastric prostaglandins. Keywords: Peptic ulcer, Medicinal plants, Phytotherapy, Annona

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