106 results on '"Wisner DH"'
Search Results
2. Presentations and outcomes of children with intraventricular hemorrhages after blunt head trauma.
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Lichenstein R, Glass TF, Quayle KS, Wootton-Gorges SL, Wisner DH, Miskin M, Muizelaar JP, Badawy M, Atabaki S, Holmes JF, Kuppermann N, and Traumatic Brain Injury Study Group of the Pediatric Emergency Care Applied Research Network (PECARN)
- Published
- 2012
3. Does this adult patient have a blunt intra-abdominal injury?
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Nishijima DK, Simel DL, Wisner DH, Holmes JF, Nishijima, Daniel K, Simel, David L, Wisner, David H, and Holmes, James F
- Abstract
Context: Blunt abdominal trauma often presents a substantial diagnostic challenge. Well-informed clinical examination can identify patients who require further diagnostic evaluation for intra-abdominal injuries after blunt abdominal trauma.Objective: To systematically assess the precision and accuracy of symptoms, signs, laboratory tests, and bedside imaging studies to identify intra-abdominal injuries in patients with blunt abdominal trauma.Data Sources: We conducted a structured search of MEDLINE (1950-January 2012) and EMBASE (1980-January 2012) to identify English-language studies examining the identification of intra-abdominal injuries. A separate, structured search was conducted for studies evaluating bedside ultrasonography.Study Selection: We included studies of diagnostic accuracy for intra-abdominal injury that compared at least 1 finding with a reference standard of abdominal computed tomography, diagnostic peritoneal lavage, laparotomy, autopsy, and/or clinical course for intra-abdominal injury. Twelve studies on clinical findings and 22 studies on bedside ultrasonography met inclusion criteria for data extraction.Data Extraction: Critical appraisal and data extraction were independently performed by 2 authors.Data Synthesis: The prevalence of intra-abdominal injury in adult emergency department patients with blunt abdominal trauma among all evidence level 1 and 2 studies was 13% (95% CI, 10%-17%), with 4.7% (95% CI, 2.5%-8.6%) requiring therapeutic surgery or angiographic embolization of injuries. The presence of a seat belt sign (likelihood ratio [LR] range, 5.6-9.9), rebound tenderness (LR, 6.5; 95% CI, 1.8-24), hypotension (LR, 5.2; 95% CI, 3.5-7.5), abdominal distention (LR, 3.8; 95% CI, 1.9-7.6), or guarding (LR, 3.7; 95% CI, 2.3-5.9) suggest an intra-abdominal injury. The absence of abdominal tenderness to palpation does not rule out an intra-abdominal injury (summary LR, 0.61; 95% CI, 0.46-0.80). The presence of intraperitoneal fluid or organ injury on bedside ultrasound assessment is more accurate than any history and physical examination findings (adjusted summary LR, 30; 95% CI, 20-46); conversely, a normal ultrasound result decreases the chance of injury detection (adjusted summary LR, 0.26; 95% CI, 0.19-0.34). Test results increasing the likelihood of intra-abdominal injury include a base deficit less than -6 mEq/L (LR, 18; 95% CI, 11-30), elevated liver transaminases (LR range, 2.5-5.2), hematuria (LR range, 3.7-4.1), anemia (LR range, 2.2-3.3), and abnormal chest radiograph (LR range, 2.5-3.8). Symptoms and signs may be most useful in combination, particularly in identification of patients who do not need further diagnostic workup.Conclusions: Bedside ultrasonography has the highest accuracy of all individual findings, but a normal result does not rule out an intra-abdominal injury. Combinations of clinical findings may be most useful to determine which patients do not require further evaluation, but the ideal combination of variables for identifying patients without intra-abdominal injury requires further study. [ABSTRACT FROM AUTHOR]- Published
- 2012
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4. Is definitive abdominal evaluation required in blunt trauma victims undergoing urgent extra-abdominal surgery?
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Schauer BA, Nguyen H, Wisner DH, and Holmes JF
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- 2005
5. Handsewn versus stapled anastomosis in penetrating colon injuries requiring resection: a multicenter study.
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Demetriades D, Murray JA, Chan LS, Ordoñez C, Bowley D, Nagy KK, Cornwell EE III, Velmahos GC, Muñoz N, Hatzitheofilou C, Schwab CW, Rodriguez A, Cornejo C, Davis KA, Namias N, Wisner DH, Ivatury RR, Moore EE, Acosta JA, and Maull KI
- Published
- 2002
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6. Penetrating colon injuries requiring resection: diversion or primary anastomosis? An AAST Prospective Multicenter Study.
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Demetriades D, Murray JA, Chan L, Ordoñez C, Bowley D, Nagy KK, Cornwell EE III, Velmahos GC, Muñoz N, Hatzitheofilou C, Schwab CW, Rodriguez A, Cornejo C, Davis KA, Namias N, Wisner DH, Ivatury RR, Moore EE, Acosta JA, and Maull KI
- Published
- 2001
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7. Abdominal ultrasound examination in pregnant blunt trauma patients.
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Goodwin H, Holmes JF, and Wisner DH
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- 2001
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8. Basal release of nitric oxide and its interaction with endothelin-1 on single vessel hydraulic permeability.
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Victorino GP, Wisner DH, and Tucker VL
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- 2001
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9. Basal release of endothelin-1 and the influence of the ETB receptor on single vessel hydraulic permeability.
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Victorino GP, Wisner DH, and Tucker VL
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- 2000
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10. Syncope-related trauma: rationale and yield of diagnostic studies.
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Morrison JE, Wisner DH, and Ramos L
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- 1999
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11. Prospective study of blunt aortic injury: Multicenter Trial of the American Association for the Surgery of Trauma.
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Fabian TC, Richardson JD, Croce MA, Smith JS Jr, Rodman G Jr, Kearney PA, Flynn W, Ney AL, Cone JB, Luchette FA, Wisner DH, Scholten DJ, Beaver BL, Conn AK, Coscia R, Hoyt DB, Morris JA Jr, Harviel JD, Peitzman AB, and Bynoe RP
- Published
- 1997
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12. Reliability of prehospital triage criteria for pregnant blunt trauma patients
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Goodwin, HC, Wisner, DH, and Holmes, JF
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- 1999
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13. Improving blood pressure screening and control at an academic health system.
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Shaikh U, Petray J, and Wisner DH
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- Academic Medical Centers organization & administration, Academic Medical Centers statistics & numerical data, Academic Medical Centers trends, Adolescent, Adult, Aged, Blood Pressure Determination trends, California, Female, Humans, Hypertension diagnosis, Hypertension physiopathology, Male, Mass Screening methods, Mass Screening trends, Middle Aged, Quality Improvement, Blood Pressure Determination standards, Mass Screening standards
- Abstract
The goal of the University of California Davis Health Blood Pressure (BP) Quality Improvement Initiative was to improve the diagnosis, management and control of high BP. Patients aged 18-85 years were included in the initiative. Lean A3 problem solving was used to implement the following evidence-based interventions based on stakeholder interviews, value stream mapping and the Centers for Disease Control and Prevention's Million Hearts Initiative: staff training on accurate BP measurement, visual cues and reminders for BP screening, virtual case-based videoconferences, standardised clinical management algorithm, academic detailing visits, clinical decision support tools, access to pharmacists for medication comanagement, clinician workflow modification, patient education and access to home BP monitors. Following implementation of interventions, accurate screening of BP increased from 14% to 87% and BP control increased from 62% to 75%. Strategies that contributed the most to improvements were using a team-based approach, adjusting clinic workflow and frequent communication of results to staff., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2020
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14. Understandability and Actionability of Online Information on Hypertension.
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Visla J, Shatola A, Wisner DH, and Shaikh U
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- Comprehension, Health Literacy, Humans, Consumer Health Information, Hypertension, Internet
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- 2019
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15. The Financial Impact of the Affordable Care Act on a Level-1 Orthopedic Trauma Service.
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Beck CJ, Shelton TJ, Wisner DH, and Wolinsky PR
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- Fees and Charges statistics & numerical data, Fees and Charges trends, Humans, Insurance, Health, Reimbursement trends, Medicaid economics, Medically Uninsured statistics & numerical data, Medicare economics, Medicare trends, Orthopedics trends, Patient Protection and Affordable Care Act statistics & numerical data, Retrospective Studies, Trauma Centers trends, United States epidemiology, Insurance, Health, Reimbursement economics, Orthopedics economics, Orthopedics statistics & numerical data, Patient Protection and Affordable Care Act economics, Trauma Centers economics, Trauma Centers statistics & numerical data
- Abstract
Objectives: To determine the impact of the Affordable Care Act (ACA) on professional fees and proportion of payer type for an orthopedic trauma service at a level-1 trauma center., Methods: We analyzed professional fee data and payer mix for the 18 months before and after implementation of the ACA. Data were collected for inpatients (IP) and outpatients (OP). We corrected for changes in patient volume between the 2-time periods by calculating average values per patient., Results: Post ACA, we treated a higher percentage of patients with Medicaid and had a reduction in the percentage of uninsured/county payers. Collections for IPs decreased $75.49/patient and OPs decreased $0.10/patient. Our collection rate decreased 6% for IPs and 5% for OPs. In particular, Medicaid collections decreased by $180/IP, and $4/OP, and Medicare decreased by $61/IP and increased $5/OP post ACA, whereas contract collections increased by $140/IP and $20/OP. The changes in our own institution's insurance were mixed with decreases of $514/IP for partial risk and $735/IP for full-risk insurance and increases of $1/OP for partial risk, and $35/OP for full-risk insurance., Conclusions: Post ACA, we saw less patients, primarily in the OP setting. This shift was accompanied by a significant decrease in our collection rate; specifically, a decrease in the amount we collected per Medicaid patient-the category of payer that increased post ACA. The ACA did allow more uninsured patients access to medical care but was associated with lower IP and OP reimbursements.
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- 2019
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16. Approaches to Distal Upper-Extremity Trauma: A Comparison of Plastic, Orthopedic, and Hand Surgeons in Academic Practice.
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Dasari CR, Sandhu M, Wisner DH, and Wong MS
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- Humans, Orthopedic Procedures methods, Orthopedics, Plastic Surgery Procedures methods, Surgery, Plastic, United States, Arm Injuries surgery, Hand Injuries surgery, Healthcare Disparities statistics & numerical data, Orthopedic Procedures statistics & numerical data, Practice Patterns, Physicians' statistics & numerical data, Plastic Surgery Procedures statistics & numerical data
- Abstract
Background: Hand trauma call duties at university medical centers are traditionally split among plastic surgeons and orthopedic surgeons, frequently without additional fellowship training in hand and upper-extremity surgery. Differences in operative approach between these groups have never been specifically described. The University Health Consortium-Association of American Medical Colleges Faculty Practice Solutions Center database contains comprehensive, factual, billing and coding data from 90 academic medical centers in the United States and can be used to characterize the practice patterns of various academic surgical specialties., Objective: To characterize and compare the clinical experience of academic plastic, orthopedic, and hand surgeons in addressing traumatic distal upper extremity injuries (using the Faculty Practice Solutions Center data set)., Methods: Annual data for CPT defined procedures related to traumatic injuries of the nail bed, finger, hand, wrist, and forearm performed by plastic, orthopedic, and hand surgeons during calendar years 2010 to 2013 were included in the study., Results: From 2010 to 2013, the experience of fellowship-trained hand surgeons in treating traumatic distal upper extremity injuries was consistently greater than that of plastic surgeons and general orthopedic surgeons across all categories. Injuries of the nail bed were repaired more frequently by plastic surgeons than orthopedic surgeons (average 1.3 annual procedures per surgeon for plastic surgeons compared with 0.3 for orthopedic surgeons). Fractures and dislocations involving the phalanx and metacarpal were repaired equally by both groups, with plastic surgeons using predominantly percutaneous (38%) or open methods (45% of repairs), and orthopedic surgeons using mostly closed reduction (59% of repairs), splinting, and casting. Fractures and dislocations involving the carpal bones, radius, and ulna were more frequently repaired by orthopedic surgeons (average 23.2 procedures versus 2.6 for plastic surgeons), whereas tendon repairs in all segments were performed more frequently by plastic surgeons (average 13.7 procedures versus 2.5 for orthopedic surgeons). Replantation and repair of neurovascular injuries were exceedingly rare (less than 1 occurrence) in all groups for all years and are not specifically reported in Table 1. Similarly, incision and drainage procedures and decompressive fasciotomies of the distal upper extremity were uncommonly performed and also not included (Table 1 displays the mean annual procedures per surgeon by grouped CPT coded procedures, with overall averages displayed to the right. Figure 1 displays the proportions of intra-articular and extra-articular bony hand injuries treated by closed, open, and percutaneous methods by each specialty)., Conclusions: A large degree of variation exists in the treatment of distal upper extremity injuries, based on specialty service. Hand surgeons, not surprisingly, have the most robust clinical experience, whereas plastic surgeons and orthopedic surgeons each display varying strengths and weaknesses, perhaps a consequence of their respective training.
- Published
- 2016
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17. Management of children with solid organ injuries after blunt torso trauma.
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Wisner DH, Kuppermann N, Cooper A, Menaker J, Ehrlich P, Kooistra J, Mahajan P, Lee L, Cook LJ, Yen K, Lillis K, and Holmes JF
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- Adolescent, Child, Child, Preschool, Female, Humans, Male, Prospective Studies, Kidney injuries, Liver injuries, Spleen injuries, Torso injuries, Wounds, Nonpenetrating diagnosis, Wounds, Nonpenetrating therapy
- Abstract
Background: Management of children with intra-abdominal solid organ injuries has evolved markedly. We describe the current management of children with intra-abdominal solid organ injuries after blunt trauma in a large multicenter network., Methods: We performed a planned secondary analysis of a prospective, multicenter observational study of children (<18 years) with blunt torso trauma. We included children with spleen, liver, or kidney injuries identified by computed tomography, laparotomy/laparoscopy, or autopsy. Outcomes included disposition and interventions (blood transfusion for intra-abdominal hemorrhage, angiography, laparotomy/laparoscopy). We performed subanalyses of children with isolated injuries., Results: A total of 12,044 children were enrolled; 605 (5.0%) had intra-abdominal solid organ injuries. The mean (SD) age was 10.7 (5.1) years, and injured organs included spleen 299 (49.4%), liver 282 (46.6%), and kidney 147 (24.3%). Intraperitoneal fluid was identified on computed tomography in 461 (76%; 95% confidence interval [CI], 73-80%), and isolated solid organ injuries were present in 418 (69%; 95% CI, 65-73%). Treatment included therapeutic laparotomy in 17 (4.1%), angiographic embolization in 6 (1.4%), and blood transfusion in 46 (11%) patients. Laparotomy rates for isolated injury were 11 (5.4%) of 205 (95% CI, 2.7-9.4%) at non-freestanding children's hospitals and 6 (2.8%) of 213 (95% CI, 1.0-6.0%) at freestanding children's hospitals (difference, 2.6%; 95% CI, -7.1% to 12.2%). Dispositions of the 212 children with isolated Grade I or II organ injuries were home in 6 (3%), emergency department observation in 9 (4%), ward in 114 (54%), intensive care unit in 73 (34%), operating suite in 7 (3%), and transferred in 3 (1%) patients. Intensive care unit admission for isolated Grade I or II injuries varied by center from 9% to 73%., Conclusion: Most children with solid organ injuries are managed with observation. Blood transfusion, while uncommon, is the most frequent therapeutic intervention; angiographic embolization and laparotomy are uncommon. Emergency department disposition of children with isolated Grade I to II solid organ injuries is highly variable and often differs from published guidelines., Level of Evidence: Prognostic/epidemiologic study, level III; therapeutic study, level IV.
- Published
- 2015
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18. Rise in microsurgical free-flap breast reconstruction in academic medical practices.
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Dasari CR, Gunther S, Wisner DH, Cooke DT, Gold CK, and Wong MS
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- Female, Humans, Free Tissue Flaps statistics & numerical data, Mammaplasty methods, Mammaplasty statistics & numerical data, Practice Patterns, Physicians', Surgery, Plastic
- Abstract
Background: Previous studies have examined national trends in breast reconstruction, using various data sets demonstrating increases in implant-based reconstruction and decreases in autologous reconstruction. However, academic breast reconstruction practices have never been specifically characterized. The University Health Consortium-Association of American Medical Colleges Faculty Practice Solutions Center database contains comprehensive, factual billing and coding data from 90 academic medical centers in the United States, and has been used to characterize practice patterns of various academic surgical specialties., Objective: To describe breast reconstruction trends unique to academic surgical practices, using the Faculty Practice Solutions Center database., Methods: Annual data for defined breast reconstruction procedures (current procedural terminology codes: 19340, 19342, 19357, 19361, 19364, 19366, 19367, 19369, and 19380) performed by university plastic surgeons during calendar years 2007 to 2013 were included in the study., Results: From 2007 to 2013, a 2-fold increase in the number of breast reconstruction procedures was observed (from a mean of 45.3 to 94.2 procedures per surgeon). During this period, implant-based reconstructions and autologous reconstructions rose in tandem (28.9-44.6 and 11.4-19.3, respectively), with a preserved 2.5:1 ratio between the 2 categories each year. When compared to reconstructions overall, the proportion of both implant reconstruction and autologous reconstruction procedures declined, since revision and other types of reconstructions increased (11% of all reconstructions in 2007 vs 32% in 2013). With regard to autologous reconstruction, microsurgical free flaps (mostly comprised of deep inferior epigastric artery perforator flaps) have supplanted latissimus flaps as the favored modality and comprised 13% to 14% of breast reconstruction cases overall from 2011 to 2013., Conclusion: In contrast to national trends, university-based plastic surgeons are performing a growing number of microsurgical free flaps as the preferred method for autologous breast reconstruction. Whereas implant-based reconstructions still predominate in academic practices, the trend of increasing preference toward implant-based reconstructions has slowed in recent years and revision reconstructions are on the rise.
- Published
- 2015
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19. The modern acute care surgeon: characterization of an evolving surgical niche.
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Pottenger BC, Galante JM, and Wisner DH
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- Current Procedural Terminology, Humans, Relative Value Scales, Critical Care trends, Practice Patterns, Physicians' trends, Specialties, Surgical trends, Traumatology trends
- Abstract
Background: Trauma and emergency surgery continues to evolve as a surgical niche. The simple fact that The Journal of Trauma is now entitled The Journal of Trauma and Acute Care Surgery captures this reality. We sought to characterize the niche that trauma and emergency surgeons have occupied during the maturation of the acute care surgery model., Methods: We analyzed the University Health System Consortium-Association of American Medical Colleges Faculty Practice Solutions Center database for the years 2007 to 2012 for specific current procedural terminology (CPT) codes. This database includes coding and billing data for more than 90 academic medical centers throughout the United States. We analyzed frequency counts and work relative value units (wRVUs) generated for specific codes to characterize the average trauma and emergency surgeon's work experience over time., Results: We found that acute care surgeons generated 42.4% of wRVUs from procedural work and 57.6% from cognitive work. For cognitive work, critical care services generated the most wRVUs per year (25.2% of total), and subsequent hospital care was the most frequently performed activity (1,236.6 codes generated per year). For procedural work, laparoscopic cholecystectomies produced the most wRVUs per year (2.4% of total), and placement of a nontunneled catheter was the most frequently performed procedure (42.2 times per year). The average acute care surgeon performed the following numbers of procedures per year: 29.6 cholecystectomies and 20.0 appendectomies; 7.7 wound vacuum device changes; 5.9 implantation of mesh procedures; 4.9 splenectomies and 0.4 splenorrhaphies; 2.6 perirectal abscess drainage procedures; less than one component separation fascial hernia repair; and less than one video-assisted thoracic surgery., Conclusion: The modern acute care surgeon is a hybrid of critical care medicine physician and ever-evolving surgical interventionist. Acute care surgeons continue to do traditional trauma work while increasingly performing acute care surgeries. The work of acute care surgeons serves a growing role and fills a valuable niche in our health care system.
- Published
- 2015
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20. Association between the seat belt sign and intra-abdominal injuries in children with blunt torso trauma in motor vehicle collisions.
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Borgialli DA, Ellison AM, Ehrlich P, Bonsu B, Menaker J, Wisner DH, Atabaki S, Olsen CS, Sokolove PE, Lillis K, Kuppermann N, and Holmes JF
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- Abdominal Injuries epidemiology, Abdominal Injuries etiology, Adolescent, Child, Female, Follow-Up Studies, Glasgow Coma Scale, Humans, Incidence, Male, Physical Examination methods, Prospective Studies, Tomography, X-Ray Computed, United States epidemiology, Wounds, Nonpenetrating epidemiology, Wounds, Nonpenetrating etiology, Abdominal Injuries diagnosis, Accidents, Traffic, Emergency Service, Hospital, Seat Belts, Wounds, Nonpenetrating diagnosis
- Abstract
Objectives: The objective was to determine the association between the abdominal seat belt sign and intra-abdominal injuries (IAIs) in children presenting to emergency departments with blunt torso trauma after motor vehicle collisions (MVCs)., Methods: This was a planned subgroup analysis of prospective data from a multicenter cohort study of children with blunt torso trauma after MVCs. Patient history and physical examination findings were documented before abdominal computed tomography (CT) or laparotomy. Seat belt sign was defined as a continuous area of erythema, ecchymosis, or abrasion across the abdomen secondary to a seat belt restraint. The relative risk (RR) of IAI with 95% confidence intervals (CIs) was calculated for children with seat belt signs compared to those without. The risk of IAI in those patients with seat belt sign who were without abdominal pain or tenderness, and with Glasgow Coma Scale (GCS) scores of 14 or 15, was also calculated., Results: A total of 3,740 children with seat belt sign documentation after blunt torso trauma in MVCs were enrolled; 585 (16%) had seat belt signs. Among the 1,864 children undergoing definitive abdominal testing (CT, laparotomy/laparoscopy, or autopsy), IAIs were more common in patients with seat belt signs than those without (19% vs. 12%; RR = 1.6, 95% CI = 1.3 to 2.1). This difference was primarily due to a greater risk of gastrointestinal injuries (hollow viscous or associated mesentery) in those with seat belt signs (11% vs. 1%; RR = 9.4, 95% CI = 5.4 to 16.4). IAI was diagnosed in 11 of 194 patients (5.7%; 95% CI = 2.9% to 9.9%) with seat belt signs who did not have initial complaints of abdominal pain or tenderness and had GCS scores of 14 or 15., Conclusions: Patients with seat belt signs after MVCs are at greater risk of IAI than those without seat belt signs, predominately due to gastrointestinal injuries. Although IAIs are less common in alert patients with seat belt signs who do not have initial complaints of abdominal pain or tenderness, the risk of IAI is sufficient that additional evaluation such as observation, laboratory studies, and potentially abdominal CT scanning is generally necessary., (© 2014 by the Society for Academic Emergency Medicine.)
- Published
- 2014
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21. Practice patterns of academic general thoracic and adult cardiac surgeons.
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Ingram MT Jr, Wisner DH, and Cooke DT
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- Academic Medical Centers, Adult, Cardiac Surgical Procedures education, Cardiac Surgical Procedures statistics & numerical data, Databases, Factual, Humans, Retrospective Studies, Thoracic Surgical Procedures education, United States, Practice Patterns, Physicians' statistics & numerical data, Thoracic Surgical Procedures statistics & numerical data
- Abstract
Objective: We hypothesized that academic adult cardiac surgeons (CSs) and general thoracic surgeons (GTSs) would have distinct practice patterns of, not just case-mix, but also time devoted to outpatient care, involvement in critical care, and work relative value unit (wRVU) generation for the procedures they perform., Methods: We queried the University Health System Consortium-Association of American Medical Colleges Faculty Practice Solution Center database for fiscal years 2007-2008, 2008-2009, and 2009-2010 for the frequency of inpatient and outpatient current procedural terminology coding and wRVU data of academic GTSs and CSs. The Faculty Practice Solution Center database is a compilation of productivity and payer data from 86 academic institutions., Results: The greatest wRVU generating current procedural terminology codes for CSs were, in order, coronary artery bypass grafting, aortic valve replacement, and mitral valve replacement. In contrast, open lobectomy, video-assisted thoracic surgery wedge, and video-assisted thoracic surgery lobectomy were greatest for GTSs. The 10 greatest wRVU-generating procedures for CSs generated more wRVUs than those for GTSs (P<.001). Although CSs generated significantly more hospital inpatient evaluation and management (E & M) wRVUs than did GTSs (P<.001), only 2.5% of the total wRVUs generated by CSs were from E & M codes versus 18.8% for GTSs. Critical care codes were 1.5% of total evaluation and management billing for both CSs and GTSs., Conclusions: Academic CSs and GTSs have distinct practice patterns. CSs receive greater reimbursement for services because of the greater wRVUs of the procedures performed compared with GTSs, and evaluation and management coding is a more important wRVU generator for GTSs. The results of our study could guide academic CS and GTS practice structure and time prioritization., (Copyright © 2014 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.)
- Published
- 2014
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22. Use of the focused assessment with sonography for trauma (FAST) examination and its impact on abdominal computed tomography use in hemodynamically stable children with blunt torso trauma.
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Menaker J, Blumberg S, Wisner DH, Dayan PS, Tunik M, Garcia M, Mahajan P, Page K, Monroe D, Borgialli D, Kuppermann N, and Holmes JF
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- Abdominal Injuries physiopathology, Adolescent, Child, Female, Hemodynamics, Humans, Male, Practice Patterns, Physicians' statistics & numerical data, Prospective Studies, Risk, Thoracic Injuries physiopathology, Tomography, X-Ray Computed statistics & numerical data, Ultrasonography, Wounds, Nonpenetrating physiopathology, Abdominal Injuries diagnostic imaging, Thoracic Injuries diagnostic imaging, Wounds, Nonpenetrating diagnostic imaging
- Abstract
Background: The aim of this study was to evaluate the variability of clinician-performed Focused Assessment with Sonography for Trauma (FAST) examinations and its impact on abdominal computed tomography (AbCT) use in hemodynamically stable children with blunt torso trauma (BTT). The FAST is used with variable frequency in children with BTT., Methods: We performed a planned secondary analysis of children (<18 years) with BTT. Patients with a Glasgow Coma Scale (GCS) score of less than 9, those with hypotension, and those taken directly to the operating suite were excluded. Clinicians documented their suspicion for intra-abdominal injury (IAI) as very low, less than 1%; low, 1% to 5%; moderate, 6% to 10%; high, 11% to 50%; or very high, greater than 50%. We determined the relative risk (RR) for AbCT use based on undergoing a FAST examination in each of these clinical suspicion strata., Results: Of 6,468 (median age, 11.8 years; interquartile range, 6.3-15.5 years) children who met eligibility, 887 (13.7%) underwent FAST examination before CT scan. A total of 3,015 (46.6%) underwent AbCT scanning, and 373 (5.8%) were diagnosed with IAI. Use of the FAST increased as clinician suspicion for IAI increased, 11.0% with less than 1% suspicion for IAI, 13.5% with 1% to 5% suspicion, 20.5% with 6% to 10% suspicion, 23.2% with 11% to 50% suspicion, and 30.7% with greater than 50% suspicion. The patients in whom the clinicians had a suspicion of IAI of 1% to 5% or 6% to 10% were significantly less likely to undergo a CT scan if a FAST examination was performed: RR, 0.83 (0.67-1.03); RR, 0.81 (0.72-0.91); RR, 0.85 (0.78-0.94); RR, 0.99 (0.94-1.05); and RR, 0.97 (0.91-1.05) for patients with clinician suspicion of IAI of less than 1%, 1% to 5%, 6% to 10%, 11% to 50%, and greater than 50%, respectively., Conclusion: The FAST examination is used in a relatively small percentage of children with BTT. Use increases as clinician suspicion for IAI increases. Patients with a low or moderate clinician suspicion of IAI are less likely to undergo AbCT if they receive a FAST examination. A randomized controlled trial is required to more precisely determine the benefits and drawbacks of the FAST examination in the evaluation of children with BTT., Level of Evidence: Prognostic and epidemiologic study, II.
- Published
- 2014
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23. A multicenter study of the risk of intra-abdominal injury in children after normal abdominal computed tomography scan results in the emergency department.
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Kerrey BT, Rogers AJ, Lee LK, Adelgais K, Tunik M, Blumberg SM, Quayle KS, Sokolove PE, Wisner DH, Miskin ML, Kuppermann N, and Holmes JF
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- Abdominal Injuries epidemiology, Adolescent, Child, Child, Preschool, Humans, Prospective Studies, Risk Factors, Sensitivity and Specificity, Abdominal Injuries diagnostic imaging, Emergency Service, Hospital, Thoracic Injuries diagnostic imaging, Tomography, X-Ray Computed, Wounds, Nonpenetrating diagnostic imaging
- Abstract
Study Objective: We determine whether intra-abdominal injury is rarely diagnosed after a normal abdominal computed tomography (CT) scan result in a large, generalizable sample of children evaluated in the emergency department (ED) after blunt torso trauma., Methods: This was a planned analysis of data collected during a prospective study of children evaluated in one of 20 EDs in the Pediatric Emergency Care Applied Research Network. The study sample consisted of patients with normal results for abdominal CT scans performed in the ED. The principal outcome measure was the negative predictive value of CT for any intra-abdominal injury and those undergoing acute intervention., Results: Of 12,044 enrolled children, 5,380 (45%) underwent CT scanning in the ED; for 3,819 of these scan the results were normal. Abdominal CT had a sensitivity of 97.8% (717/733; 95% confidence interval [CI] 96.5% to 98.7%) and specificity of 81.8% (3,803/4,647; 95% CI 80.7% to 82.9%) for any intra-abdominal injury. Sixteen (0.4%; 95% CI 0.2% to 0.7%) of the 3,819 patients with normal CT scan results later received a diagnosis of an intra-abdominal injury, and 6 of these underwent acute intervention for an intra-abdominal injury (0.2% of total sample; 95% CI 0.06% to 0.3%). The negative predictive value of CT for any intra-abdominal injury was 99.6% (3,803/3,819; 95% CI 99.3% to 99.8%); and for injury undergoing acute intervention, 99.8% (3,813/3,819; 95% CI 99.7% to 99.9%)., Conclusion: In a multicenter study of children evaluated in EDs after blunt torso trauma, intra-abdominal injuries were rarely diagnosed after a normal abdominal CT scan result, suggesting that safe discharge is possible for the children when there are no other reasons for admission., (Copyright © 2013 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved.)
- Published
- 2013
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24. Extremity soft tissue tumor surgery by surgical specialty: a comparison of case volume among oncology and non-oncology-designated surgeons.
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Canter RJ, Smith CA, Martinez SR, Goodnight JE Jr, Bold RJ, and Wisner DH
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- Extremities, Humans, Medical Oncology, Quality of Health Care, Surgical Procedures, Operative statistics & numerical data, Soft Tissue Neoplasms surgery, Specialties, Surgical
- Abstract
Introduction: We sought to characterize the extent of extremity soft tissue tumor (ESTT) resections among surgical specialties, hypothesizing that substantial variation exists in the number of ESTT resections performed by specialty., Methods: We queried the UHC-AAMC database for data from 85 institutions for years 2007-2009. We abstracted data on total number of musculoskeletal (MSK) procedures, number of subcutaneous (SQ), deep, and malignant ESTT resections, and anatomic site of resection. Data were available for 4,682 practitioners including the following specialties: general surgery (GS, N = 2,195), plastic surgery (PS, N = 792), surgical oncology (SO, N = 533), general orthopedics (GO, N = 1,079), and orthopedic oncology (OO, N = 83)., Results: The mean number of all MSK procedures performed per year was 19.0 ± 2.3 GS, 179.6 ± 3.0 PS, 32.4 ± 6.2 SO, 798.6 ± 115.4 GO, and 482.9 ± 6.5 OO (P = 0.001). SQ ESTT resections per year were similar among specialties (1.7 ± 0.3 GS, 2.7 ± 0.3 PS, 2.4 ± 0.4 SO, 1.7 ± 0.5 GO, 4.7 ± 0.2 OO), while deep and malignant resections were more likely performed by OO (combined deep and malignant: 0.9 ± 0.1 GS, 2.0 ± 0.4 PS, 9.9 ± 0.6 SO, 5.8 ± 0.3 GO, and 63.6 ± 8.1 OO, P = 0.001). Adjusting for number of physicians in the database, of the total deep and malignant ESTT resections, 9.4% were performed by GS, 7.7% by PS, 26.0% by SO, 30.8% by GO, and 26.0% by OO., Conclusion: Nearly 50% of deep and malignant ESTT resections are performed by non-oncology-designated surgeons. Approximately 17% are performed by practitioners who complete an average of one to two of these procedures per year. These findings may have significant implications for quality of care in soft tissue tumor surgery., (Copyright © 2013 Wiley Periodicals, Inc.)
- Published
- 2013
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25. Identifying children at very low risk of clinically important blunt abdominal injuries.
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Holmes JF, Lillis K, Monroe D, Borgialli D, Kerrey BT, Mahajan P, Adelgais K, Ellison AM, Yen K, Atabaki S, Menaker J, Bonsu B, Quayle KS, Garcia M, Rogers A, Blumberg S, Lee L, Tunik M, Kooistra J, Kwok M, Cook LJ, Dean JM, Sokolove PE, Wisner DH, Ehrlich P, Cooper A, Dayan PS, Wootton-Gorges S, and Kuppermann N
- Subjects
- Female, Humans, Male, Appendicitis diagnosis, Decision Support Techniques
- Abstract
Study Objective: We derive a prediction rule to identify children at very low risk for intra-abdominal injuries undergoing acute intervention and for whom computed tomography (CT) could be obviated., Methods: We prospectively enrolled children with blunt torso trauma in 20 emergency departments. We used binary recursive partitioning to create a prediction rule to identify children at very low risk of intra-abdominal injuries undergoing acute intervention (therapeutic laparotomy, angiographic embolization, blood transfusion for abdominal hemorrhage, or intravenous fluid for ≥2 nights for pancreatic/gastrointestinal injuries). We considered only historical and physical examination variables with acceptable interrater reliability., Results: We enrolled 12,044 children with a median age of 11.1 years (interquartile range 5.8, 15.1 years). Of the 761 (6.3%) children with intra-abdominal injuries, 203 (26.7%) received acute interventions. The prediction rule consisted of (in descending order of importance) no evidence of abdominal wall trauma or seat belt sign, Glasgow Coma Scale score greater than 13, no abdominal tenderness, no evidence of thoracic wall trauma, no complaints of abdominal pain, no decreased breath sounds, and no vomiting. The rule had a negative predictive value of 5,028 of 5,034 (99.9%; 95% confidence interval [CI] 99.7% to 100%), sensitivity of 197 of 203 (97%; 95% CI 94% to 99%), specificity of 5,028 of 11,841 (42.5%; 95% CI 41.6% to 43.4%), and negative likelihood ratio of 0.07 (95% CI 0.03 to 0.15)., Conclusion: A prediction rule consisting of 7 patient history and physical examination findings, and without laboratory or ultrasonographic information, identifies children with blunt torso trauma who are at very low risk for intra-abdominal injury undergoing acute intervention. These findings require external validation before implementation., (Copyright © 2012 American College of Emergency Physicians. Published by Mosby, Inc. All rights reserved.)
- Published
- 2013
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26. Flexion and extension radiographic evaluation for the clearance of potential cervical spine injures in trauma patients.
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McCracken B, Klineberg E, Pickard B, and Wisner DH
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Female, Humans, Magnetic Resonance Imaging methods, Male, Middle Aged, Posture, Retrospective Studies, Tomography, X-Ray Computed methods, Young Adult, Cervical Vertebrae diagnostic imaging, Spinal Injuries diagnostic imaging
- Abstract
Background: Flexion and extension radiographs are often used in the setting of trauma to clear a cervical spine injury. The utility of such tests, however, remains to be determined. We hypothesized that in patients who underwent a negative computed tomography (CT) cervical spine scan, flexion and extension radiographs did not yield useful additional information., Methods: We conducted a retrospective chart review of all patients admitted to a Level I trauma center who had a negative CT scan of the cervical spine and a subsequent cervical flexion-extension study for evaluation of potential cervical spine injury. All flexion-extension films were independently reviewed to determine adequacy as defined by C7/T1 visualization and 30° of change in the angle from flexion to extension. The independent reviews were compared to formal radiology readings and the influence of the flexion-extension studies on clinical decision making was also reviewed., Results: One thousand patients met inclusion criteria for the study. Review of the flexion-extension radiographs revealed that 80% of the films either did not adequately demonstrate the C7/T1 junction or had less than 30° range of motion. There was one missed injury that was also missed on magnetic resonance imaging. Results of the flexion-extension views had minimal effects on clinical decision making., Conclusion: Adequate flexion extension films are difficult to obtain and are minimally helpful for clearance of the cervical spine in awake and alert trauma patients.
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- 2013
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27. Nomograms to predict risk of in-hospital and post-discharge venous thromboembolism after abdominal and thoracic surgery: an American College of Surgeons National Surgical Quality Improvement Program analysis.
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Shah DR, Wang H, Bold RJ, Yang X, Martinez SR, Yang AD, Khatri VP, Wisner DH, and Canter RJ
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- Adult, Aged, Female, Humans, Incidence, Male, Middle Aged, Nomograms, Patient Discharge, Quality Improvement, Risk Assessment, Societies, Medical, Thoracic Surgical Procedures, United States epidemiology, Postoperative Complications epidemiology, Venous Thromboembolism epidemiology
- Abstract
Background: Postoperative venous thromboembolism (VTE) is increasingly viewed as a quality of care metric, although risk-adjusted incident rates of postoperative VTE and VTE after hospital discharge (VTEDC) are not available. We sought to characterize the predictors of VTE and VTEDC to develop nomograms to estimate individual risk of VTE and VTEDC., Methods: Using the American College of Surgeons National Surgical Quality Improvement Program database, we identified 471,867 patients who underwent inpatient abdominal or thoracic operations between 2005 and 2010. We excluded primary vascular and spine operations. We built logistic regression models using stepwise model selection and constructed nomograms for VTE and VTEDC with statistically significant covariates., Results: The overall, unadjusted, 30-d incidence of VTE and VTEDC was 1.5% and 0.5%, respectively. Annual incidence rates remained unchanged over the study period. On multivariate analysis, age, body mass index, presence of preoperative infection, operation for cancer, procedure type (spleen highest), multivisceral resection, and non-bariatric laparoscopic surgery were significant predictors for VTE and VTEDC. Other significant predictors for VTE, but not VTEDC, included a history of chronic obstructive pulmonary disease, disseminated cancer, and emergent operation. We constructed and validated nomograms by bootstrapping. The concordance indices for VTE and VTEDC were 0.77 and 0.67, respectively., Conclusions: Substantial variation exists in the incidence of VTE and VTEDC, depending on patient and procedural factors. We constructed nomograms to predict individual risk of 30-d VTE and VTEDC. These may allow more targeted quality improvement interventions to reduce VTE and VTEDC in high-risk general and thoracic surgery patients., (Copyright © 2013 Elsevier Inc. All rights reserved.)
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- 2013
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28. Who performs complex noncardiac thoracic surgery in United States academic medical centers?
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Cooke DT and Wisner DH
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- Humans, United States, Workforce, Academic Medical Centers, Internship and Residency, Specialties, Surgical education, Thoracic Surgery education, Thoracic Surgery, Video-Assisted education
- Abstract
Background: We hypothesized that general thoracic surgeons (GTS) predominantly perform complex noncardiac thoracic surgery in academic hospitals compared with cardiac surgeons (CS), general surgeons, and surgical oncologists., Methods: Fiscal year 2007-2008 to 2009-2010 coding and work relative value unit data from the University Health System Consortium and Association of American Medical Colleges Faculty Practice Solutions Center database, which includes 86 academic institutions, was analyzed. Procedural groups for pneumonectomy, other pulmonary resection (including lobectomy, bilobectomy, segmentectomy, sleeve lobectomy, and video-assisted thoracoscopic surgery lobectomy-segmentectomy), and esophagectomy were evaluated., Results: Of the 1,989,055.3 total work relative value units generated for complex noncardiac thoracic surgical procedures during the study period, 77.5% were generated by GTS, compared with 9.9% by CS, 8.9% by general surgeons, and 3.7% by surgical oncologists (p<0.001). General thoracic surgeons averaged 2.1 pneumonectomies, 51.1 other pulmonary resections, and 12.2 esophagectomies per year compared with 2.1 pneumonectomies, 9.4 other pulmonary resections, and less than 1 esophagectomy per year for CS. General surgeons and surgical oncologists averaged no more than 1.6 cases per year for all categories (all p<0.001, except for pneumonectomy, in which GTS versus CS was not significantly different). To determine the use of parenchymal-sparing operations, we looked at the ratio of sleeve lobectomy to pneumonectomy and found higher usage of parenchymal-sparing techniques by GTS, relative to pneumonectomy, compared with all other groups (p<0.001). General thoracic surgeons averaged 16.0 video-assisted thoracoscopic surgery lobectomies per year compared with approximately 1 per year for all other groups (p<0.001). General thoracic surgeons had a 47.1% increase in video-assisted thoracoscopic surgery lobectomies per year compared with 27.4% for CS., Conclusions: In academic hospitals, noncardiac thoracic surgery is performed mostly by GTS, supporting academic GTS as a distinct specialty. These results may help determine hospital referral and credentialing policies, and plan general and cardiothoracic surgery residency curriculum., (Copyright © 2012 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.)
- Published
- 2012
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29. Indications and performance of pelvic radiography in patients with blunt trauma.
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Holmes JF and Wisner DH
- Subjects
- Adult, Fractures, Bone surgery, Glasgow Coma Scale, Humans, Middle Aged, Pelvic Bones diagnostic imaging, Pelvic Bones surgery, Prospective Studies, Tomography, X-Ray Computed, Fractures, Bone diagnostic imaging, Pelvic Bones injuries, Wounds, Nonpenetrating diagnostic imaging
- Abstract
Objectives: The objectives of this study are to validate a set of clinical variables to identify patients with pelvic fractures and to determine the sensitivity of anteroposterior (AP) pelvic radiographs in patients with pelvic fractures., Methods: We conducted a prospective observational cohort study of adults (>18 years) with blunt torso trauma evaluated with abdominal/pelvic computed tomography. Physicians providing care in the emergency department documented history and physical examination findings after initial evaluation. High-risk variables included any of the following: hypotension (systolic blood pressure <90 mm Hg), Glasgow Coma Scale score less than 14, pelvic bone tenderness, or instability. Pelvic fractures were present if the orthopedic faculty documented a fracture to the pubis, ilium, ischium, or sacrum., Results: We enrolled 4737 patients, including 289 (6.1%; 95% confidence interval [CI], 5.4%-6.8%) with pelvic fractures. Of the 289 patients, 256 (88.6%; 95% CI, 84.3%-92.0%) had at least one of the high-risk variables identified. Initial plain AP radiographs identified 234 (81.0%; 95% CI, 76.0%-85.3%) of 289 patients with pelvic fractures. The high-risk variables identified all 87 patients (100%; 95% CI, 96.6%-100%) undergoing surgery, whereas plain AP pelvic radiography identified a fracture in 83 patients (95.4%; 95% CI, 88.6%-98.7%) undergoing surgery., Conclusion: Previously identified high-risk variables for pelvic fracture identify most but not all patients with pelvic fractures. However, these high-risk variables identify all patients undergoing surgery and may be implemented as screening criteria for pelvic radiography. Anteroposterior pelvic radiographs fail to demonstrate a fracture in a substantial number of patients with pelvic fracture including patients who undergo surgery., (Copyright © 2012 Elsevier Inc. All rights reserved.)
- Published
- 2012
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30. Rate of intra-abdominal injury after a normal abdominal computed tomographic scan in adults with blunt trauma.
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Holmes JF, McGahan JP, and Wisner DH
- Subjects
- Adult, Female, Humans, Male, Middle Aged, Patient Admission statistics & numerical data, Prospective Studies, Risk Factors, Trauma Centers statistics & numerical data, Young Adult, Abdominal Injuries diagnostic imaging, Tomography, X-Ray Computed, Wounds, Nonpenetrating diagnostic imaging
- Abstract
Objective: The objective of this study is to determine the rate of intra-abdominal injury (IAI) in adults with blunt abdominal trauma after a normal abdominal computed tomographic (CT) scan. We hypothesize that the risk of subsequent IAI is so low that hospital admission and observation for possible IAI are unnecessary., Methods: We conducted a prospective, observational cohort study of adults (>18 years) with blunt trauma who underwent abdominal CT scanning in the emergency department. Computed tomographic scans were obtained with intravenous contrast but no oral contrast. Abnormalities on abdominal CT included all visualized IAIs or any finding suggestive of possible IAI. Patients were followed up to determine the presence or absence of IAI and the need for therapeutic intervention if IAI was identified., Results: Of the 3103 patients undergoing abdominal CT, 2734 (88%) had normal CT scans. The median age was 39 years (interquartile range, 26-51 years); and 2141 (78%) were admitted to the hospital. Eight (0.3%; 95% confidence interval, 0.1%-0.6%) were identified with IAIs after normal abdominal CT scans including the following injuries: pancreas (5), liver (4), gastrointestinal (2), and spleen (2). Five underwent therapy at laparotomy. Abdominal CT had a likelihood ratio (+) of 20.9 (95% confidence interval, 17.7-24.8) and likelihood ratio (-) of 0.034 (0.017-0.068)., Conclusion: Adult patients with blunt torso trauma and normal abdominal CT scans are at low risk for subsequently identified IAI. Thus, hospitalization for evaluation of possible IAI after a normal abdominal CT scan is unnecessary in most cases., (Copyright © 2012 Elsevier Inc. All rights reserved.)
- Published
- 2012
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31. Multiplex polymerase chain reaction pathogen detection in patients with suspected septicemia after trauma, emergency, and burn surgery.
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Tran NK, Wisner DH, Albertson TE, Cohen S, Greenhalgh D, Palmieri TL, Polage C, and Kost GJ
- Subjects
- Adult, Aged, Blood microbiology, Burns complications, Burns surgery, Emergencies, Female, Humans, Male, Middle Aged, Postoperative Complications diagnosis, Postoperative Complications etiology, Postoperative Complications microbiology, Prospective Studies, Sepsis drug therapy, Sepsis etiology, Treatment Outcome, Wounds and Injuries complications, Young Adult, Microbiological Techniques, Multiplex Polymerase Chain Reaction, Sepsis diagnosis, Sepsis microbiology
- Abstract
Background: The goal of this study is to determine the clinical value of multiplex polymerase chain reaction (PCR) study for enhancing pathogen detection in patients with suspected septicemia after trauma, emergency, and burn surgery. PCR-based pathogen detection quickly reveals occult bloodstream infections in these high-risk patients and may accelerate the initiation of targeted antimicrobial therapy., Methods: We conducted a prospective observational study comparing results for 30 trauma and emergency surgery patients to 20 burn patients. Whole-blood samples collected with routine blood cultures (BCs) were tested using a new multiplex, PCR-based, pathogen detection system. PCR results were compared to culture data., Results: PCR detected rapidly more pathogens than culture methods. Acute Physiology and Chronic Health Evaluation II (APACHE II), Sequential Organ Failure Assessment (SOFA), and Multiple Organ Dysfunction (MODS) scores were greater in PCR-positive versus PCR-negative trauma and emergency surgery patients (P ≤ .033). Negative PCR results (odds ratio, 0.194; 95% confidence interval, 0.045-0.840; P = .028) acted as an independent predictor of survival for the combined surgical patient population., Conclusion: PCR detected the presence of pathogens more frequently than blood culture. These PCR results were reported faster than blood culture results. Severity scores were significantly greater in PCR-positive trauma and emergency surgery patients. The lack of pathogen DNA as determined by PCR served as a significant predictor of survival in the combined patient population. PCR testing independent of traditional prompts for culturing may have clinical value in burn patients. These results warrant further investigation through interventional trials., (Copyright © 2012 Mosby, Inc. All rights reserved.)
- Published
- 2012
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32. Trauma surgery to acute care surgery: defining the paradigm shift.
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Galante JM, Phan HH, and Wisner DH
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- Abscess surgery, Appendectomy trends, Benchmarking, Cholecystectomy trends, Critical Care trends, Drainage trends, Emergency Medicine trends, Health Services Research, Humans, Laparoscopy trends, Models, Organizational, Neoplasms surgery, Rectal Diseases surgery, Relative Value Scales, United States, Acute Disease therapy, General Surgery trends, Practice Patterns, Physicians' trends, Specialization trends, Traumatology trends, Vascular Surgical Procedures trends
- Abstract
Background: Trauma surgery is gradually evolving into acute care surgery (ACS). We sought to better define this evolution by using work relative value units (wRVU) to characterize the current practices of trauma and ACS., Methods: Fiscal year 2007-2008 data from the UHC-AAMC Faculty Practice Solutions Center database, which is comprised of coding or billing data from 85 institutions was used. We compared averages for trauma surgeons with general, oncology, and vascular surgeons., Results: Trauma surgeons are distinct from other surgical specialties; only 43% of their total wRVU were procedural compared to 69% to 75% for vascular, surgical oncology, and general surgeons. The total procedures for each specialty were similar: trauma 660, general surgery 715, surgical oncology 713, vascular 835, but trauma surgeons performed more bedside procedures. Of the top 20 total wRVU generating procedures, 20% of trauma surgeon's were bedside compared to 0% of a general surgeon's. The wRVU or surgeon for cholecystectomy were comparable between trauma and general surgery (388 vs. 452); both groups perform about 75% of the cholecystectomies laparoscopically. With respect to appendectomies, wRVU or surgeon for trauma surgeons (180) exceeded general surgeons (128). Each group performed approximately 65% laparoscopically., Conclusions: Trauma surgeons are distinctly different from their colleagues, with a greater emphasis on intensive care unit "cognitive" work. The number of procedures performed by trauma surgeons is comparable to other disciplines but with more "bedside" procedures. Trauma surgeons' high appendectomy wRVUs may be a reflection of the transition to an ACS model. The characterization of trauma surgery as nonoperative and intensive care unit-based is in part substantiated but there are indications of a paradigm shift toward more operative experience with transition to an ACS model.
- Published
- 2010
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33. Should we increase the ratio of plasma/platelets to red blood cells in massive transfusion: what is the evidence?
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Phan HH and Wisner DH
- Subjects
- Acidosis etiology, Acidosis therapy, Adolescent, Child, Erythrocyte Transfusion, Hemorrhagic Disorders etiology, Hemorrhagic Disorders therapy, Humans, Hypothermia etiology, Hypothermia therapy, Military Medicine methods, Military Personnel, Plasma, Platelet Transfusion, Retrospective Studies, Shock, Hemorrhagic etiology, Shock, Hemorrhagic mortality, Shock, Hemorrhagic therapy, Survival Analysis, Treatment Outcome, Wounds and Injuries complications, Wounds and Injuries therapy, Wounds, Penetrating complications, Wounds, Penetrating therapy, Blood Component Transfusion methods
- Abstract
Introduction: Based on relatively recent clinical work, considerable enthusiasm has been generated for the increased use of plasma and platelet in the earlier resuscitation of massively transfused patients. The aim of this review was to examine the currently available evidence for the increase in plasma/platelet to red cell transfusion ratio during massive transfusion., Methods: In May of 2009, a systematic review of studies reporting the effects of plasma and platelet to red cell component transfusion ratio on mortality outcome was performed., Results: There were no prospective randomized controlled trials on this topic. Eleven retrospective studies were identified evaluating the effects of plasma : red cell ratio on mortality in massive transfusion after trauma. Most studies demonstrated a survival advantage of increased plasma ratio in massive transfusion. While the majority of the studies suggested the optimal plasma : red cell ratio to be 1 : 2 or higher, others demonstrated the optimal ratio to be lower. Three of these studies also demonstrated a survival advantage with increased platelet : red cell transfusion ratio., Conclusion: Although there is some evidence to support the increase use of plasma and platelets in massive transfusion, the true efficacy of such practice has not yet been proven by prospective randomized controlled trials. The available retrospective studies raise many important questions that need to be addressed in future clinical trials.
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- 2010
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34. Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort study.
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Kuppermann N, Holmes JF, Dayan PS, Hoyle JD Jr, Atabaki SM, Holubkov R, Nadel FM, Monroe D, Stanley RM, Borgialli DA, Badawy MK, Schunk JE, Quayle KS, Mahajan P, Lichenstein R, Lillis KA, Tunik MG, Jacobs ES, Callahan JM, Gorelick MH, Glass TF, Lee LK, Bachman MC, Cooper A, Powell EC, Gerardi MJ, Melville KA, Muizelaar JP, Wisner DH, Zuspan SJ, Dean JM, and Wootton-Gorges SL
- Subjects
- Algorithms, Biomechanical Phenomena, Brain Injuries diagnostic imaging, Brain Injuries mortality, Child, Child, Preschool, Decision Trees, Emergency Medicine methods, Humans, Intubation, Intratracheal statistics & numerical data, Patient Admission statistics & numerical data, Patient Selection, Pediatrics methods, Predictive Value of Tests, Prospective Studies, Risk Assessment standards, Risk Factors, Severity of Illness Index, Brain Injuries etiology, Craniocerebral Trauma complications, Craniocerebral Trauma diagnosis, Decision Support Techniques, Risk Assessment methods, Tomography, X-Ray Computed adverse effects, Tomography, X-Ray Computed statistics & numerical data
- Abstract
Background: CT imaging of head-injured children has risks of radiation-induced malignancy. Our aim was to identify children at very low risk of clinically-important traumatic brain injuries (ciTBI) for whom CT might be unnecessary., Methods: We enrolled patients younger than 18 years presenting within 24 h of head trauma with Glasgow Coma Scale scores of 14-15 in 25 North American emergency departments. We derived and validated age-specific prediction rules for ciTBI (death from traumatic brain injury, neurosurgery, intubation >24 h, or hospital admission >or=2 nights)., Findings: We enrolled and analysed 42 412 children (derivation and validation populations: 8502 and 2216 younger than 2 years, and 25 283 and 6411 aged 2 years and older). We obtained CT scans on 14 969 (35.3%); ciTBIs occurred in 376 (0.9%), and 60 (0.1%) underwent neurosurgery. In the validation population, the prediction rule for children younger than 2 years (normal mental status, no scalp haematoma except frontal, no loss of consciousness or loss of consciousness for less than 5 s, non-severe injury mechanism, no palpable skull fracture, and acting normally according to the parents) had a negative predictive value for ciTBI of 1176/1176 (100.0%, 95% CI 99.7-100 0) and sensitivity of 25/25 (100%, 86.3-100.0). 167 (24.1%) of 694 CT-imaged patients younger than 2 years were in this low-risk group. The prediction rule for children aged 2 years and older (normal mental status, no loss of consciousness, no vomiting, non-severe injury mechanism, no signs of basilar skull fracture, and no severe headache) had a negative predictive value of 3798/3800 (99.95%, 99.81-99.99) and sensitivity of 61/63 (96.8%, 89.0-99.6). 446 (20.1%) of 2223 CT-imaged patients aged 2 years and older were in this low-risk group. Neither rule missed neurosurgery in validation populations., Interpretation: These validated prediction rules identified children at very low risk of ciTBIs for whom CT can routinely be obviated., Funding: The Emergency Medical Services for Children Programme of the Maternal and Child Health Bureau, and the Maternal and Child Health Bureau Research Programme, Health Resources and Services Administration, US Department of Health and Human Services.
- Published
- 2009
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35. Validation of a prediction rule for the identification of children with intra-abdominal injuries after blunt torso trauma.
- Author
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Holmes JF, Mao A, Awasthi S, McGahan JP, Wisner DH, and Kuppermann N
- Subjects
- Adolescent, Child, Child, Preschool, Critical Pathways, Emergency Service, Hospital, False Negative Reactions, Female, Humans, Infant, Male, Prospective Studies, Sensitivity and Specificity, Abdominal Injuries diagnostic imaging, Decision Support Techniques, Tomography, X-Ray Computed, Wounds, Nonpenetrating diagnostic imaging
- Abstract
Study Objective: We validate the accuracy of a previously derived clinical prediction rule for the identification of children with intra-abdominal injuries after blunt torso trauma., Methods: We conducted a prospective observational study of children with blunt torso trauma who were evaluated for intra-abdominal injury with abdominal computed tomography (CT), diagnostic laparoscopy, or laparotomy at a Level I trauma center during a 3-year period to validate a previously derived prediction rule. The emergency physician providing care documented history and physical examination findings on a standardized data collection form before knowledge of the results of diagnostic imaging. The clinical prediction rule being evaluated included 6 "high-risk" variables, the presence of any of which indicated that the child was not at low risk for intra-abdominal injury: low age-adjusted systolic blood pressure, abdominal tenderness, femur fracture, increased liver enzyme levels (serum aspartate aminotransferase concentration >200 U/L or serum alanine aminotransferase concentration >125 U/L), microscopic hematuria (urinalysis >5 RBCs/high powered field), or an initial hematocrit level less than 30%., Results: One thousand three hundred twenty-four children with blunt torso trauma were enrolled, and 1,119 (85%) patients had the variables in the decision rule documented by the emergency physician and therefore made up the study sample. The prediction rule had the following test characteristics: sensitivity=149 of 157, 94.9% (95% confidence interval [CI] 90.2% to 97.7%) and specificity=357 of 962, 37.1% (95% CI 34.0 to 40.3%). Three hundred sixty-five patients tested negative for the rule; thus, strict application would have resulted in a 33% reduction in abdominal CT scanning. Of the 8 patients with intra-abdominal injury not identified by the prediction rule, 1 underwent a laparotomy. This patient had a serosal tear and a mesenteric hematoma at laparotomy, neither of which required specific surgical intervention., Conclusion: A clinical prediction rule consisting of 6 variables, easily available to clinicians in the ED, identifies most but not all children with intra-abdominal injury. Application of the prediction rule to this sample would have reduced the number of unnecessary abdominal CT scans performed but would have failed to identify 1 child undergoing (a nontherapeutic) laparotomy. Thus, further refinement of this prediction rule in a large, multicenter cohort is necessary before widespread implementation.
- Published
- 2009
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36. Clinical prediction rules for identifying adults at very low risk for intra-abdominal injuries after blunt trauma.
- Author
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Holmes JF, Wisner DH, McGahan JP, Mower WR, and Kuppermann N
- Subjects
- Abdominal Injuries complications, Adolescent, Adult, Critical Pathways, Female, Glasgow Coma Scale, Hematocrit, Hematuria complications, Hip Fractures complications, Humans, Male, Middle Aged, Pneumothorax complications, Prospective Studies, Rib Fractures complications, Sensitivity and Specificity, Tomography, X-Ray Computed, Young Adult, Abdominal Injuries diagnostic imaging, Abdominal Injuries etiology, Decision Support Techniques, Emergency Service, Hospital, Wounds, Nonpenetrating complications
- Abstract
Study Objective: We derive and validate clinical prediction rules to identify adult patients at very low risk for intra-abdominal injuries after blunt torso trauma., Methods: We prospectively enrolled adult patients (>or=18 years old) after blunt torso trauma for whom diagnostic testing for intra-abdominal injury was performed. In the derivation phase, we used binary recursive partitioning to create a rule to identify patients with intra-abdominal injury who were undergoing acute intervention (including therapeutic laparotomy or angiographic embolization) and a separate rule for identifying patients with any intra-abdominal injury present. We considered only clinical variables readily available with acceptable interrater reliability. The prediction rules were then prospectively validated in a separate cohort of patients., Results: In the derivation phase, we enrolled 3,435 patients, including 311 (9.1%; 95% confidence interval [CI] 8.1% to 10.1%) with intra-abdominal injury and 109 (35.0%; 95% CI 29.7% to 40.6%) with intra-abdominal injury requiring acute intervention. In the validation study, we enrolled 1,595 patients, including 143 (9.0%; 95% CI 7.6% to 10.5%) with intra-abdominal injury. The derived rule for patients with intra-abdominal injuries who were undergoing acute intervention consisted of hypotension, Glasgow Coma Scale (GCS) score less than 14, costal margin tenderness, abdominal tenderness, hematuria level greater than or equal to 25 red blood cells/high powered field, and hematocrit level less than 30% and identified all 44 patients in the validation phase with intra-abdominal injury who were undergoing acute intervention (sensitivity 44/44, 100%; 95% CI 93.4% to 100%). The derived rule for the presence of any intra-abdominal injury consisted of GCS score less than 14, costal margin tenderness, abdominal tenderness, femur fracture, hematuria level greater than or equal to 25 red blood cells/high powered field, hematocrit level less than 30%, and abnormal chest radiograph result (pneumothorax or rib fracture). In the validation phase, the rule for any intra-abdominal injury present had the following test performance: sensitivity 137 of 143 (95.8%; 95% CI 91.1% to 98.4%), specificity 434 of 1,452 (29.9%; 95% CI 27.5% to 32.3%), and negative predictive value 434 of 440 (98.6%; 95% CI 97.1% to 99.5%)., Conclusion: These derived and validated clinical prediction rules can aid physicians in the evaluation of adult patients after blunt torso trauma. Patients without any of these variables are at very low risk for having intra-abdominal injury, particularly intra-abdominal injury requiring acute intervention, and are unlikely to benefit from abdominal computed tomography scanning.
- Published
- 2009
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37. Interhospital transfer occurs more slowly for elderly acute trauma patients.
- Author
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Utter GH, Victorino GP, and Wisner DH
- Subjects
- Age Factors, Aged, California, Chi-Square Distribution, Female, Humans, Injury Severity Score, Linear Models, Male, Retrospective Studies, Statistics, Nonparametric, Time Factors, Tomography, X-Ray Computed statistics & numerical data, Patient Transfer statistics & numerical data, Trauma Centers
- Abstract
The objective of this study was to determine whether elderly acutely injured patients take longer to be transferred from referring hospitals to a regional trauma center than younger patients. We reviewed all trauma patients transferred urgently to a regional trauma center over 2 years. We considered age>or=65 years to be elderly. We performed multivariable linear regression to determine the extra time spent at the referring hospital attributable to elderly status, after adjustment for confounders. For 371 transfers, mean Injury Severity Score was 12, and 12% of patients had hypotension before transfer. Mean time spent at the referring hospital was 233+/-110 min. After adjustment for confounders, including Injury Severity Score and computed tomography (CT) scanning before transfer, elderly patients spent 32 min more at referring hospitals than non-elderly patients (95% confidence interval 1-63 min). We conclude that interhospital transfer of elderly acutely injured trauma patients takes longer than for younger patients. Providers may be less aggressive in treating elderly trauma patients.
- Published
- 2008
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38. Is hospital admission and observation required after a normal abdominal computed tomography scan in children with blunt abdominal trauma?
- Author
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Awasthi S, Mao A, Wooton-Gorges SL, Wisner DH, Kuppermann N, and Holmes JF
- Subjects
- Child, Emergency Service, Hospital, Female, Humans, Male, Observation, Prospective Studies, Abdominal Injuries diagnostic imaging, Patient Admission statistics & numerical data, Tomography, X-Ray Computed, Wounds, Nonpenetrating diagnostic imaging
- Abstract
Objectives: The objective was to determine if hospital admission of children with blunt abdominal trauma for observation of possible intraabdominal injury (IAI) is necessary after a normal abdominal computed tomography (CT) scan in the emergency department (ED)., Methods: The authors conducted a prospective observational cohort study of children less than 18 years of age with blunt abdominal trauma who underwent an abdominal CT scan in the ED. Abdominal CT scans were obtained with intravenous contrast but no oral contrast. The decision to hospitalize the patient was made by the attending emergency physician (EP) with the trauma or pediatric surgery teams. An abnormal abdominal CT scan was defined by the presence of any visualized IAI or findings suggestive of possible IAI (e.g., intraperitoneal fluid without solid organ injury). Patients were followed to determine if IAI was later diagnosed and the need for acute therapeutic intervention if IAI was present., Results: A total of 1,295 patients underwent abdominal CT, and 1,085 (84%) patients had normal abdominal CT scans in the ED and make up the study population. Seven-hundred thirty-seven (68%) were hospitalized, and 348 were discharged to home. None of the 348 patients discharged home and 2 of the 737 hospitalized patients were identified with an IAI after a normal initial abdominal CT. The IAIs in patients with normal initial CT scans included a 10-year-old with a mesenteric hematoma and serosal tear at laparotomy and a 10-year-old with a perinephric hematoma on repeat CT. Neither underwent specific therapy. The negative predictive value (NPV) of a normal abdominal CT scan for IAI was 99.8% (95% confidence interval [CI] = 99.3% to 100%)., Conclusions: Children with blunt abdominal trauma and a normal abdominal CT scan in the ED are at very low risk of having a subsequently diagnosed IAI and are very unlikely to require a therapeutic intervention. Hospitalization of children for evaluation of possible undiagnosed IAI after a normal abdominal CT scan has a low yield and is generally unnecessary.
- Published
- 2008
- Full Text
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39. Appearance of solid organ injury with contrast-enhanced sonography in blunt abdominal trauma: preliminary experience.
- Author
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McGahan JP, Horton S, Gerscovich EO, Gillen M, Richards JR, Cronan MS, Brock JM, Battistella F, Wisner DH, and Holmes JF
- Subjects
- Abdominal Injuries pathology, Adult, Contrast Media administration & dosage, Female, Humans, Male, Middle Aged, Sensitivity and Specificity, Tomography, X-Ray Computed, Ultrasonography, Wounds, Nonpenetrating pathology, Abdominal Injuries diagnostic imaging, Wounds, Nonpenetrating diagnostic imaging
- Abstract
Objective: The purpose of this study was to compare the detection rate of injury and characterize imaging findings of contrast-enhanced sonography and non-contrast-enhanced sonography in the setting of confirmed solid organ injury., Subjects and Methods: This prospective study involved identifying hepatic, splenic, and renal injuries on contrast-enhanced CT. After injury identification, both non-contrast-enhanced sonography and contrast-enhanced sonography were performed to identify the possible injury and to analyze the appearance of the injury. The sonographic appearance of hepatic, splenic, and renal injuries was then analyzed, and the conspicuity of the injuries was graded on a scale from 0 (nonvisualization) to 3 (high visualization)., Results: Non-contrast-enhanced sonography revealed 11 (50%) of 22 injuries, whereas contrast-enhanced sonography depicted 20 (91%) of 22 injuries. The average grade for conspicuity of injuries was increased from 0.67 to 2.33 for spleen injuries and from 1.0 to 2.2 for liver injuries comparing non-contrast-enhanced with contrast-enhanced sonography, respectively, on a scale from 0, being nonvisualization, to 3, being high visualization. The splenic injuries appeared hypoechoic with occasional areas of normal enhancing splenic tissue within the laceration with contrast-enhanced sonography. Different patterns were observed in liver injuries including a central hypoechoic region. In some liver injuries there was a surrounding hyperechoic region., Conclusion: Contrast-enhanced sonography greatly enhances visualization of liver and spleen injuries compared with non-contrast-enhanced sonography. Solid organ injuries usually appeared hypoechoic on contrast-enhanced sonography, but often a hyperechoic region surrounding the injury also was identified with liver injuries.
- Published
- 2006
- Full Text
- View/download PDF
40. Do all patients with left costal margin injuries require radiographic evaluation for intraabdominal injury?
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Holmes JF, Ngyuen H, Jacoby RC, McGahan JP, Bozorgchami H, and Wisner DH
- Subjects
- Abdominal Injuries complications, Abdominal Injuries diagnostic imaging, Adolescent, Adult, Aged, Aged, 80 and over, Child, Cohort Studies, Emergency Medicine methods, Humans, Middle Aged, Outcome and Process Assessment, Health Care, Prospective Studies, Radiography, Rib Fractures complications, Rib Fractures diagnostic imaging, Spleen diagnostic imaging, Flank Pain etiology, Spleen injuries, Thoracic Injuries complications, Thoracic Injuries diagnostic imaging, Wounds, Nonpenetrating complications, Wounds, Nonpenetrating diagnostic imaging
- Abstract
Study Objective: We determine whether all patients with pain or tenderness to the left lower ribs after blunt traumatic injury require abdominal computed tomography (CT) scanning for the detection of splenic injury., Methods: This was a prospective, observational cohort of all blunt-trauma patients who had pain or tenderness to the left lower ribs and presented to the emergency department (ED) of a Level I trauma center. Patients were enrolled if they had a Glasgow Coma Scale (GCS) score greater than 13 and pain or tenderness to the left lower ribs (ribs 7 to 12). Patients with pain or tenderness to the left lower ribs were considered to have pleuritic pain if the pain increased with inspiration or cough. All hemodynamically stable patients underwent abdominal CT scanning for detection of intraabdominal injuries. Data forms collecting information on the medical history and physical examination of all patients were completed before radiographic imaging. Patients with left lower rib pain or tenderness were considered to have "isolated" left lower rib injury if they were without all of the following: ED or out-of-hospital systolic blood pressure less than 90 mm Hg, abdominal or flank tenderness, pelvic or femur fractures, and gross hematuria., Results: Eight hundred seventy-five patients had left lower rib pain or tenderness, 63 (7.2%; 95% confidence interval [CI] 5.6% to 9.1%) patients had splenic injuries, and 20 (2.3%; 95% CI 1.4% to 3.5%) patients had left renal injuries. Five hundred seventy-four patients had additional indications for abdominal imaging, leaving 301 patients with "isolated" left lower rib injury. Of the 301 patients, 9 (3.0%; 95% CI 1.4% to 5.6%) had splenic injuries. All 9 patients had a pleuritic component to their rib tenderness, and 3 (33%) patients underwent splenectomy., Conclusion: A small but important percentage of patients with pain or tenderness to the left lower ribs has splenic injuries. All patients with splenic injury had pleuritic pain.
- Published
- 2005
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41. Blunt cardiac rupture in a patient with prior ventricular septal defect repair: a case report.
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Utter GH, Scherer LA, and Wisner DH
- Subjects
- Adult, Heart Injuries diagnostic imaging, Humans, Male, Radiography, Wounds, Nonpenetrating diagnostic imaging, Heart Injuries surgery, Heart Septal Defects, Ventricular surgery, Multiple Trauma surgery, Wounds, Nonpenetrating surgery
- Published
- 2004
- Full Text
- View/download PDF
42. Performance of helical computed tomography without oral contrast for the detection of gastrointestinal injuries.
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Holmes JF, Offerman SR, Chang CH, Randel BE, Hahn DD, Frankovsky MJ, and Wisner DH
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Contrast Media administration & dosage, Female, Humans, Infant, Male, Middle Aged, Predictive Value of Tests, Radiography, Abdominal statistics & numerical data, Registries statistics & numerical data, Retrospective Studies, Sensitivity and Specificity, Tomography, Spiral Computed statistics & numerical data, Trauma Centers statistics & numerical data, Wounds, Nonpenetrating diagnostic imaging, Digestive System injuries, Emergency Service, Hospital statistics & numerical data, Radiography, Abdominal methods, Tomography, Spiral Computed methods, Wounds and Injuries diagnostic imaging
- Abstract
Study Objective: We describe the performance of helical abdominal computed tomography (CT) scan without oral contrast for the detection of blunt gastrointestinal injuries., Methods: We retrospectively reviewed the records of a consecutive series of patients who underwent helical abdominal CT scanning for evaluation of blunt intra-abdominal injury and were admitted to a Level I trauma center from May 1996 to September 2001. Abdominal CT scans were performed with intravenous contrast but without oral contrast. Patients were considered to have gastrointestinal injuries if an injury was identified to the gastrointestinal tract from the duodenum to the sigmoid colon or associated mesentery and considered to have major gastrointestinal injuries if gastrointestinal perforation, active mesenteric hemorrhage, or mesenteric devascularization occurred. All gastrointestinal injuries were confirmed by laparotomy, autopsy, or additional imaging studies., Results: Six thousand fifty-two patients underwent abdominal CT scan (mean age 35.5 +/- 21.1 years), and 106 (1.8%) patients had gastrointestinal injuries identified by laparotomy, autopsy, or additional (nonabdominal CT) imaging studies. Abdominal CT scan result was abnormal in 91 (86%; 95% confidence interval [CI] 78% to 92%) of the 106 patients with gastrointestinal injuries and revealed findings suggestive of gastrointestinal injury in 81 (76%; 95% CI 67% to 84%) patients. Abdominal CT scan demonstrated findings suggestive of gastrointestinal injury in 58 of 64 (91%; 95% CI 81% to 96%) patients with major gastrointestinal injuries. Two hundred thirty-eight (4.0%) patients had findings suspicious for gastrointestinal injuries on abdominal CT scan, but gastrointestinal injury was never confirmed., Conclusion: Helical abdominal CT scan without oral contrast identified nearly three fourths of patients with blunt gastrointestinal injuries who were selected for abdominal CT scanning. Sensitivity of this diagnostic test improves in the subset of patients with major gastrointestinal injuries.
- Published
- 2004
- Full Text
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43. Does tachycardia correlate with hypotension after trauma?
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Victorino GP, Battistella FD, and Wisner DH
- Subjects
- Adult, Female, Heart Rate physiology, Humans, Logistic Models, Male, ROC Curve, Retrospective Studies, Sensitivity and Specificity, Trauma Severity Indices, Hypotension complications, Tachycardia complications, Wounds and Injuries complications
- Abstract
Background: Tachycardia is believed to be closely associated with hypotension and is often listed as an important sign in the initial diagnosis of hemorrhagic shock, but the correlation between heart rate and hypotension remains unproved., Study Design: Data were collected from all trauma patients, 16 to 49 years old, presenting to our university-based trauma center between July 1988 and January 1997. Moribund patients with a systolic blood pressure < or =50 or heart rate < or = 40 and patients with significant head or spinal cord injuries were excluded. Tachycardia was defined as a heart rate >or= 90 and hypotension as a systolic blood pressure < 90., Results: Hypotension was present in 489 of the 14,325 admitted patients that met the entry criteria. Of the hypotensive patients, 35% (169) were not tachycardic. Tachycardia was present in 39% of patients with systolic blood pressure 120 mmHg. Hypotensive patients with tachycardia had a higher mortality (15%) compared with hypotensive patients who were not tachycardic (2%, P = 0.003). Logistic regression analysis revealed tachycardia to be independently associated with hypotension (p = 0.0004), but receiver operating curve analysis demonstrated that the sensitivity and specificity of heart rate for predicting hypotension is poor., Conclusions: Tachycardia is not a reliable sign of hypotension after trauma. Although tachycardia was independently associated with hypotension, its sensitivity and specificity limit its usefulness in the initial evaluation of trauma victims. Absence of tachycardia should not reassure the clinician about the absence of significant blood loss after trauma. Patients who are both hypotensive and tachycardic have an associated increased mortality and warrant careful evaluation.
- Published
- 2003
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44. Cricothyrotomy: a 5-year experience at one institution.
- Author
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Bair AE, Panacek EA, Wisner DH, Bales R, and Sakles JC
- Subjects
- Emergency Medical Services, Emergency Service, Hospital, Female, Humans, Male, Postoperative Complications epidemiology, Prevalence, Retrospective Studies, Tracheotomy adverse effects, Cricoid Cartilage surgery, Thyroid Cartilage surgery, Tracheotomy statistics & numerical data
- Abstract
We describe the prevalence, primary indications and immediate complications of emergency cricothyrotomy (cric) techniques, in a single institution's Emergency Department (ED) and associated air-medical transport service. This is a retrospective review at an academic, level-one trauma center with an annual ED census of 65,000 and an associated air-medical transport service (AMTS). All patients undergoing cric in the field or in the ED between July 1995 and June 2000 were included. Expert reviewers from Emergency Medicine, Trauma Surgery and the AMTS prospectively defined the complication criteria. All charts with a possible complication underwent a blinded evaluation by reviewers representing each of the three clinical services. Descriptive statistics were used to summarize the data. Fifty crics were performed over 5 years. Seventy-six percent of crics were performed in trauma patients. The prevalence of cric in patients requiring airway management in the ED was 1.1% (95% CI, 0.7-1.6) and 10.9% (95% CI, 6.9-16.1) in the field by the AMTS. The prevalence of complications was 14% (95% CI, 4-32.6) in ED patients and 54.5% (95% CI, 32-75.6) for prehospital patients. The overall inter-rater agreement for complication rate was excellent (kappa =.87). Overall, 77% of crics were performed using the rapid four-step technique (RFST). There were no reports of complications associated with the RFST when performed in the ED. Non-RFST crics in the ED had an associated complication rate of 25% (95% CI, 2.8-60). Emergency cricothyrotomy was performed in approximately 1% of all emergency airway cases in the ED and at a higher rate by the AMTS. The most frequent indications were trauma related. Additionally, the RFST was the most commonly used technique for cric at this institution. The complication rate of cric was significantly higher in the prehospital environment than in the ED.
- Published
- 2003
- Full Text
- View/download PDF
45. A simplified approach to the diagnosis of elevated intra-abdominal pressure.
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Lee SL, Anderson JT, Kraut EJ, Wisner DH, and Wolfe BM
- Subjects
- Animals, Female, Pressure, Swine, Abdomen, Manometry methods, Urinary Bladder
- Abstract
Background: Previous methods described to measure bladder pressure require additional setup, making these techniques complex and time consuming. We describe a simple U-tube technique and investigate its accuracy for measuring intra-abdominal pressure (IAP)., Methods: Warm saline was infused into the peritoneum of five pigs to increase IAP. Indirect methods of measuring IAP included bladder, inferior vena cava (IVC), and gastric pressures. Bladder pressure was measured by both the standard and U-tube technique. IVC pressure was measured via a femoral line and gastric pressure was transduced through an orogastric tube. In addition, 30 patients undergoing laparoscopy were prospectively investigated. Insufflated abdominal pressure readings were obtained and compared with bladder pressures measured by the U-tube technique (n = 20) and standard technique (n = 10)., Results: In the animal study, U-tube manometry had the highest degree of correlation (r(2) = 0.98) and the lowest bias (0.51 +/- 1.63 mm Hg). The bladder pressure measured by the U-tube technique was between 0.1 and 0.9 mm Hg less than the directly measured IAP (95% confidence interval). There was a high degree of correlation between IAP and the standard technique for bladder pressure (r(2) = 0.93), IVC pressure (r(2) = 0.93), and gastric pressure (r(2) = 0.90). Strong correlation also existed between the U-tube and standard techniques for measuring bladder pressure (r(2) = 0.96). In humans, a strong correlation between insufflated abdominal pressure and bladder pressure (U-tube technique, r(2) = 0.79; standard technique, r(2) = 0.53) was also encountered., Conclusion: The accuracy of the U-tube manometry technique for measuring intra-abdominal pressure is comparable to previously described techniques. The U-tube technique is simple, does not require additional equipment, and can be performed by any member of the medical team.
- Published
- 2002
- Full Text
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46. Effects of delaying fluid resuscitation on an injury to the systemic arterial vasculature.
- Author
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Holmes JF, Sakles JC, Lewis G, and Wisner DH
- Subjects
- Animals, Hemorrhage, Models, Animal, Resuscitation, Sheep, Thoracic Injuries, Wounds, Penetrating, Arteries injuries, Fluid Therapy, Hemodynamics, Shock, Hemorrhagic
- Abstract
Objectives: To determine the effects of delaying fluid on the rate of hemorrhage and hemodynamic parameters in an injury involving the arterial system., Methods: Twenty-one adult, anesthetized sheep underwent left anterior thoracotomy and transection of the left internal mammary artery. A chest tube was inserted into the thoracic cavity to provide a continuous measurement of blood loss. The animals were randomly assigned to one of three resuscitation protocols: 1) no fluid resuscitation (NR), 2) standard fluid resuscitation (SR) begun 15 minutes after injury, or 3) delayed fluid resuscitation (DR) begun 30 minutes after injury. All of the animals in the two resuscitation groups received 60 mL/kg of lactated Ringer's solution over 30 minutes. Blood loss and hemodynamic parameters were measured throughout the experiment., Results: Total hemorrhage volume (mean +/- SD) at the end of the experiment was significantly lower (p = 0.006) in the NR group (1,499 +/- 311 mL) than in the SR group (3,435 +/- 721 mL) or the DR group (2,839 +/- 1549 mL). Rate of hemorrhage followed changes in mean arterial pressure in all groups. Hemorrhage spontaneously ceased significantly sooner (p = 0.007) in the NR group (21 +/- 14 minutes) and the DR group (20 +/- 15 minutes) than in the SR group (54 +/- 4 minutes). In the DR group, after initial cessation of hemorrhage, hemorrhage recurred in five of six animals (83%) with initiation of fluid resuscitation. Maximum oxygen (O2) delivery in each group after injury was as follows: 101 +/- 34 mL O2/kg/min at 45 minutes in the DR group, 51 +/- 20 mL O2/kg/min at 30 minutes in the SR group, and 35 +/- 8 mL O2/kg/min at 60 minutes in the NR group., Conclusions: Rates of hemorrhage from an arterial injury are related to changes in mean arterial pressure. In this animal model, early aggressive fluid resuscitation in penetrating thoracic trauma exacerbates total hemorrhage volume. Despite resumption of hemorrhage from the site of injury, delaying fluid resuscitation results in the best hemodynamic parameters.
- Published
- 2002
- Full Text
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47. Gastric rupture and massive pneumoperitoneum after bystander cardiopulmonary resuscitation.
- Author
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Offerman SR, Holmes JF, and Wisner DH
- Subjects
- Adult, Emergencies, Humans, Male, Pneumoperitoneum diagnostic imaging, Radiography, Stomach Rupture diagnosis, Treatment Outcome, Cardiopulmonary Resuscitation adverse effects, Pneumoperitoneum etiology, Stomach Rupture etiology
- Abstract
Gastric perforation is a rare complication of cardiopulmonary resuscitation. The majority of reported cases have been associated with difficult airway management or esophageal intubation. There has been only one previous case report in which this complication could be attributed solely to mouth-to-mouth ventilation. We present a case of simple bystander cardiopulmonary resuscitation that resulted in gastric perforation.
- Published
- 2001
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48. Re.: Nitroprusside in resuscitation of major torso trauma.
- Author
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Wisner DH
- Subjects
- Blood Pressure drug effects, Humans, Shock, Hemorrhagic etiology, Thoracic Injuries complications, Nitroprusside therapeutic use, Shock, Hemorrhagic drug therapy, Vasodilator Agents therapeutic use
- Published
- 2001
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49. Spontaneous splenic rupture due to subcutaneous heparin therapy.
- Author
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Weiss SJ, Smith T, Laurin E, and Wisner DH
- Subjects
- Ascites complications, Diagnosis, Differential, Female, Hematocrit, Humans, Middle Aged, Ovarian Neoplasms complications, Peritonitis diagnosis, Pulmonary Embolism complications, Rupture, Spontaneous, Splenic Rupture blood, Splenic Rupture diagnosis, Splenic Rupture surgery, Tomography, X-Ray Computed, Venous Thrombosis complications, Anticoagulants adverse effects, Emergency Treatment methods, Heparin adverse effects, Splenic Rupture chemically induced, Venous Thrombosis drug therapy
- Abstract
We report a case of spontaneous splenic rupture in a 59-year-old woman who was receiving 15,000 units of heparin subcutaneously (s.c. ) twice a day for deep venous thrombosis (DVT) prophylaxis. Her past medical history included multiple DVT, pulmonary emboli, and ovarian cancer stage III-C with known ascites. The diagnosis of splenic rupture was initially missed because of the ascites. This case illustrates both a previously undescribed complication of s.c. heparin therapy and a failure of ultrasound diagnosis. We emphasize the unique presentation, difficulty in diagnosis, and need for early surgical involvement to ensure the most favorable outcome.
- Published
- 2000
- Full Text
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50. Methamphetamine use in trauma patients: a population-based study.
- Author
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Schermer CR and Wisner DH
- Subjects
- Alcoholic Intoxication diagnosis, Alcoholic Intoxication epidemiology, Alcoholic Intoxication ethnology, Amphetamine-Related Disorders diagnosis, Amphetamine-Related Disorders ethnology, California epidemiology, Chi-Square Distribution, Cocaine-Related Disorders complications, Cocaine-Related Disorders diagnosis, Cocaine-Related Disorders epidemiology, Cocaine-Related Disorders ethnology, Emergency Service, Hospital statistics & numerical data, Ethanol blood, Female, Humans, Logistic Models, Male, Multiple Trauma ethnology, Prevalence, Retrospective Studies, Substance Abuse Detection, Amphetamine-Related Disorders complications, Amphetamine-Related Disorders epidemiology, Central Nervous System Stimulants urine, Methamphetamine urine, Multiple Trauma complications
- Abstract
Background: There are indications that methamphetamine production and illicit use are increasing. We investigated the epidemiology of methamphetamine use in trauma patients in an area of heavy methamphetamine prevalence., Study Design: This was a retrospective population-based review. We reviewed toxicology and alcohol test results in trauma patients admitted to the University of California, Davis, between 1989 and 1994 to the only trauma center serving a population of 1.1 million., Results: Positive methamphetamine rates nearly doubled between 1989 (7.4%) and 1994 (13.4%), compared with a minimal increase in cocaine rates (5.8% to 6.2%) and a decrease in blood alcohol rates (43% to 35%). Methamphetamine-positive patients were most likely to be Caucasian or Hispanic; cocaine-positive patients were most likely to be African American. Methamphetamine-positive patients were most commonly injured in motor vehicle collisions or motorcycle collisions; cocaine-positive patients were most commonly injured by assaults, gunshot wounds, or stab wounds. Cocaine positivity and alcohol positivity predicted a decreased need for emergency surgery and cocaine positivity predicted a decreased need for admission to the ICU., Conclusions: Methamphetamine use in trauma patients increased markedly in our region between 1989 and 1994, alcohol rates decreased, and cocaine rates remained unchanged. Methamphetamine-positive patients had mechanisms of injury similar to those of alcohol-positive patients, so injury prevention strategies for methamphetamine should be patterned after strategies designed for alcohol.
- Published
- 1999
- Full Text
- View/download PDF
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