5 results on '"Young, Brett M."'
Search Results
2. Head-to-head comparison of oral contrast agents for cross-sectional enterography: small bowel distention, timing, and side effects.
- Author
-
Young BM, Fletcher JG, Booya F, Paulsen S, Fidler J, Johnson CD, Huprich J, Barlow J, and Trout A
- Subjects
- Administration, Oral, Adult, Barium Sulfate administration & dosage, Barium Sulfate adverse effects, Drug Administration Schedule, Female, Humans, Image Enhancement methods, Intestine, Small anatomy & histology, Male, Methylcellulose administration & dosage, Methylcellulose adverse effects, Patient Satisfaction, Polyethylene Glycols administration & dosage, Polyethylene Glycols adverse effects, Prospective Studies, Reference Values, Severity of Illness Index, Time Factors, Tomography, X-Ray Computed methods, Water administration & dosage, Contrast Media administration & dosage, Contrast Media adverse effects, Intestine, Small diagnostic imaging, Intestine, Small drug effects, Magnetic Resonance Imaging methods
- Abstract
Objective: To determine small bowel distention, scanning time, and side effects of commercially available oral contrast agents used in cross-sectional enterography., Methods: Ten healthy volunteers ingested 2000 mL of water, methylcellulose, polyethylene glycol (PEG), or 1350 mL of low-concentration barium (LCB) followed by 500 mL water on different days. Magnetic resonance imaging occurred every 10 minutes from 30 to 90 minutes after ingestion. Small bowel distention was compared between time points and agents. Volunteers ranked side effects, drinking difficulty, and preference., Results: By quantitative assessment, PEG and LCB distended small bowel loops better than water and methylcellulose (P < 0.0001). Time to optimal distention of the terminal ileum was from 51 to 72 minutes. Water and methylcellulose had the fewest side effects. Water was the most preferred contrast and PEG the least., Conclusions: Polyethylene glycol and LCB distend small bowel better than water and methylcellulose. Polyethylene glycol was the most difficult to drink and least preferred agent.
- Published
- 2008
- Full Text
- View/download PDF
3. Polyp measurement with CT colonography: multiple-reader, multiple-workstation comparison.
- Author
-
Young BM, Fletcher JG, Paulsen SR, Booya F, Johnson CD, Johnson KT, Melton Z, Rodysill D, and Mandrekar J
- Subjects
- Algorithms, Colonography, Computed Tomographic instrumentation, Equipment Design, Equipment Failure Analysis, Female, Humans, Imaging, Three-Dimensional methods, Male, Observer Variation, Phantoms, Imaging, Radiographic Image Enhancement methods, Radiographic Image Interpretation, Computer-Assisted methods, Reproducibility of Results, Sensitivity and Specificity, Signal Processing, Computer-Assisted, Colonic Polyps diagnostic imaging, Colonography, Computed Tomographic methods, Data Display, Imaging, Three-Dimensional instrumentation, Radiographic Image Enhancement instrumentation, Radiographic Image Interpretation, Computer-Assisted instrumentation
- Abstract
Objective: The risk of invasive colorectal cancer in colorectal polyps correlates with lesion size. Our purpose was to define the most accurate methods for measuring polyp size at CT colonography (CTC) using three models of workstations and multiple observers., Materials and Methods: Six reviewers measured 24 unique polyps of known size (5, 7, 10, and 12 mm), shape (sessile, flat, and pedunculated), and location (straight or curved bowel segment) using CTC data sets obtained at two doses (5 mAs and 65 mAs) and a previously described colonic phantom model. Reviewers measured the largest diameter of polyps on three proprietary workstations. Each polyp was measured with lung and soft-tissue windows on axial, 2D multiplanar reconstruction (MPR), and 3D images., Results: There were significant differences among measurements obtained at various settings within each workstation (p < 0.0001). Measurements on 2D images were more accurate with lung window than with soft-tissue window settings (p < 0.0001). For the 65-mAs data set, the most accurate measurements were obtained in analysis of axial images with lung window, 2D MPR images with lung window, and 3D tissue cube images for Wizard, Advantage, and Vitrea workstations, respectively, without significant differences in accuracy among techniques (0.11 < p < 0.59). The mean absolute error values for these optimal settings were 0.48 mm, 0.61 mm, and 0.76 mm, respectively, for the three workstations. Within the ultralow-dose 5-mAs data set the best methods for Wizard, Advantage, and Vitrea were axial with lung window, 2D MPR with lung window, and 2D MPR with lung window, respectively. Use of nearly all measurement methods, except for the Vitrea 3D tissue cube and the Wizard 2D MPR with lung window, resulted in undermeasurement of the true size of the polyps., Conclusion: Use of CTC computer workstations facilitates accurate polyp measurement. For routine CTC examinations, polyps should be measured with lung window settings on 2D axial or MPR images (Wizard and Advantage) or 3D images (Vitrea). When these optimal methods are used, these three commercial workstations do not differ significantly in acquisition of accurate polyp measurements at routine dose settings.
- Published
- 2007
- Full Text
- View/download PDF
4. CT enterography as a diagnostic tool in evaluating small bowel disorders: review of clinical experience with over 700 cases.
- Author
-
Paulsen SR, Huprich JE, Fletcher JG, Booya F, Young BM, Fidler JL, Johnson CD, Barlow JM, and Earnest F 4th
- Subjects
- Humans, Practice Guidelines as Topic, Practice Patterns, Physicians', Reproducibility of Results, Sensitivity and Specificity, Contrast Media, Gastrointestinal Agents, Inflammatory Bowel Diseases diagnostic imaging, Intestine, Small diagnostic imaging, Radiographic Image Enhancement methods, Tomography, X-Ray Computed methods
- Abstract
Computed tomographic (CT) enterography combines the improved spatial and temporal resolution of multi-detector row CT with large volumes of ingested neutral enteric contrast material to permit visualization of the small bowel wall and lumen. Adequate luminal distention can usually be achieved with oral hyperhydration, thereby obviating nasoenteric intubation and making CT enterography a useful, well-tolerated study for the evaluation of diseases affecting the mucosa and bowel wall. Unlike routine CT, which has been used to detect the extraenteric complications of Crohn disease such as fistula and abscess, CT enterography clearly depicts the small bowel inflammation associated with Crohn disease by displaying mural hyperenhancement, stratification, and thickening; engorged vasa recta; and perienteric inflammatory changes. As a result, CT enterography is becoming the first-line modality for the evaluation of suspected inflammatory bowel disease. CT enterography has also become an important alternative to traditional fluoroscopy in the assessment of other small bowel disorders such as celiac sprue and small bowel neoplasms., (Copyright RSNA, 2006.)
- Published
- 2006
- Full Text
- View/download PDF
5. Colonic perforation at CT colonography in a patient without known colonic disease.
- Author
-
Young BM, Fletcher JG, Earnest F, Fidler JL, MacCarty RL, Johnson CD, Huprich JE, and Hough D
- Subjects
- Aged, Aged, 80 and over, Humans, Insufflation adverse effects, Male, Colon injuries, Colonic Diseases diagnostic imaging, Colonography, Computed Tomographic adverse effects, Intestinal Perforation etiology
- Published
- 2006
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.