182 results on '"Zhang, Sai-Yang"'
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2. Strategies that regulate Hippo signaling pathway for novel anticancer therapeutics
3. Targeting focal adhesion kinase (FAK) in cancer therapy: A recent update on inhibitors and PROTAC degraders
4. Annual review of PROTAC degraders as anticancer agents in 2022
5. Design, synthesis and biological evaluation of 1,2,3-triazole benzothiazole derivatives as tubulin polymerization inhibitors with potent anti-esophageal cancer activities
6. Discovery of novel coumarin-based derivatives as inhibitors of tubulin polymerization targeting the colchicine binding site with potent anti-gastric cancer activities
7. Design, synthesis and biological evaluation of N-benzylaryl cinnamide derivatives as tubulin polymerization inhibitors capable of promoting YAP degradation with potent anti-gastric cancer activities
8. Design, synthesis and biological evaluation of novel 2,4-diaminopyrimidine cinnamyl derivatives as inhibitors of FAK with potent anti-gastric cancer activities
9. A review of progress in o-aminobenzamide-based HDAC inhibitors with dual targeting capabilities for cancer therapy
10. Tubulin degradation: Principles, agents, and applications
11. Discovery of a novel Coumarin-Dihydroquinoxalone derivative MY-673 as a tubulin polymerization inhibitor capable of inhibiting the ERK pathway with potent anti-gastric cancer activities
12. Discovery of novel N-benzylarylamide-dithiocarbamate based derivatives as dual inhibitors of tubulin polymerization and LSD1 that inhibit gastric cancers
13. Recent development of multi-target VEGFR-2 inhibitors for the cancer therapy
14. The dual FAK-HDAC inhibitor MY-1259 displays potent activities in gastric cancers in vitro and in vivo
15. New drug approvals for 2021: Synthesis and clinical applications
16. Discovery of N-benzylarylamide derivatives as novel tubulin polymerization inhibitors capable of activating the Hippo pathway
17. Discovery of novel coumarin-indole derivatives as tubulin polymerization inhibitors with potent anti-gastric cancer activities
18. Discovery of novel 1,2,4-triazine-chalcone hybrids as anti-gastric cancer agents via an axis of ROS-ERK-DR5 in vitro and in vivo
19. Design, synthesis and evaluation of novel bis-substituted aromatic amide dithiocarbamate derivatives as colchicine site tubulin polymerization inhibitors with potent anticancer activities
20. Recent progress of oridonin and its derivatives for cancer therapy and drug resistance
21. Discovery of 1,2,4-triazine dithiocarbamate derivatives as NEDDylation agonists to inhibit gastric cancers
22. A review: hippo signaling pathway promotes tumor invasion and metastasis by regulating target gene expression
23. Progress of tubulin polymerization activity detection methods
24. Discovery of novel indole derivatives that inhibit NEDDylation and MAPK pathways against gastric cancer MGC803 cells
25. Review of NEDDylation inhibition activity detection methods
26. Discovery of tertiary amide derivatives incorporating benzothiazole moiety as anti-gastric cancer agents in vitro via inhibiting tubulin polymerization and activating the Hippo signaling pathway
27. Discovery of novel tertiary amide derivatives as NEDDylation pathway activators to inhibit the tumor progression in vitro and in vivo
28. Novel tertiary sulfonamide derivatives containing benzimidazole moiety as potent anti-gastric cancer agents: Design, synthesis and SAR studies
29. Antiproliferative Evaluation In Vitro of a New Chalcone Inducing Apoptosis by ROS Generation Against MGC-803 Cells
30. Molecular diversity of trimethoxyphenyl-1,2,3-triazole hybrids as novel colchicine site tubulin polymerization inhibitors
31. Mechanisms of synergistic neurotoxicity induced by two high risk pesticide residues – Chlorpyrifos and Carbofuran via oxidative stress
32. Bioactive heterocycles containing a 3,4,5-trimethoxyphenyl fragment exerting potent antiproliferative activity through microtubule destabilization
33. Discovery of novel arylamide derivatives containing piperazine moiety as inhibitors of tubulin polymerisation with potent liver cancer inhibitory activity.
34. Antiproliferative Evaluation of (E)-3-(3-(Allyloxy)-2-Methoxyphenyl)-1-(2,4,6-Trimethoxyphenyl)Prop-2-En-1-One as a Novel Apoptosis Inducer Against Prostate Cancer PC-3 Cells
35. Discovery of 5,6-diaryl-1,2,4-triazines hybrids as potential apoptosis inducers
36. Design and synthesis of formononetin-dithiocarbamate hybrids that inhibit growth and migration of PC-3 cells via MAPK/Wnt signaling pathways
37. Molecular diversity of phenothiazines: design and synthesis of phenothiazine–dithiocarbamate hybrids as potential cell cycle blockers
38. Design, synthesis and anti-tumor activity studies of novel pyrido[3, 4-d]pyrimidine derivatives
39. Synthesis and bioactivity of novel coumarin derivatives
40. A Review of the Regulatory Mechanisms of N-Myc on Cell Cycle.
41. WITHDRAWN: Discovery of indoline derivatives as anticancer agents via inhibition of tubulin polymerization
42. Discovery of indoline derivatives as anticancer agents via inhibition of tubulin polymerization
43. The Henry reaction of (1R)-(1,4:3,6-dianhydro-d-mannitol-2-yl)-1,4:3,6-dianhydro-d-fructose 5,5′-dinitrate. Different reactive features of nitromethane to nitroethane
44. Design, Synthesis and Biological Evaluation of [1,2,4]Triazolo[1,5- a ]pyrimidine Indole Derivatives against Gastric Cancer Cells MGC-803 via the Suppression of ERK Signaling Pathway.
45. Discovery of 1,2,4-triazine-based derivatives as novel neddylation inhibitors and anticancer activity studies against gastric cancer MGC-803 cells
46. Discovery of N-aryl sulphonamide-quinazoline derivatives as anti-gastric cancer agents in vitro and in vivo via activating the Hippo signalling pathway.
47. Ras/Raf/MEK/ERK pathway axis mediated neurotoxicity induced by high‐risk pesticide residue‐Avermectin.
48. Design, synthesis and antiproliferative activity studies of novel dithiocarbamate–chalcone derivates
49. Isolation, characterization and cytotoxic activity of benzophenone glucopyranosides from Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl)
50. Design, synthesis and antiproliferative evaluation of 3-aminopropyloxy derivatives of chalcone.
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