1. Insulin pump therapy of type 1 diabetes mellitus in children and adolescents in the Moscow region
- Author
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Elena Efimovna Petryaykina, Olga Viktorovna Dukhareva, Irina Georgievna Rybkina, Ekaterina Alexandrovna Pronina, Tatiana Dmitrievna Mikhaylova, Irina Viktorovna Garyaeva, Eleonora Tavanovna Mandzhieva, Igor Eduardovich Volkov, and Natalya Mikhailovna Grenkova
- Subjects
type 1 diabetes mellitus ,children and adolescents ,insulin pump therapy ,glycated hemoglobin ,insulin requirement ,efficiency of therapy ,Nutritional diseases. Deficiency diseases ,RC620-627 - Abstract
Aim. To assess dynamics of glycated hemoglobin levels and insulin doses per kg bw in children and adolescents with poorly controlled type 1 diabetes mellitus using insulin pumps. Materials and methods. Retrospective analysis of HbA1c levels and insulin doses per kg bw in children aged 2-17 years with DM1 (mean duration 5.3?3.1) before and 18 months after onset of insulin pump therapy (Medtronic Minimed 712 and 722) with a short-acting insulin analog Novopramid (Novo Nordisk) or Humalog (Ely Lilly) given to 55 (52,4%) and 50 (47,6%) of the patients respectively. НbА1с level and mean daily insulin dose per kg bw were determined when a patient visited the doctors office every 3 months. Results. Insulin pump therapy in patients with initially poorly controlled DM1 resulted in a decrease of HbA1c from 9.8?0.8 to 7,8?0,5% within 18 months after its beginning (p
- Published
- 2009
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