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Your search keyword '"Toxicity Tests methods"' showing total 2 results
Start Over Descriptor "Toxicity Tests methods" Language finnish
2 results on '"Toxicity Tests methods"'

1. [Non-animal toxicology in the safety testing of chemicals].

Author

Heinonen T and Tähti H

Subjects
Animals, Consumer Product Safety, Humans, Animal Testing Alternatives, Toxicity Tests methods
Abstract

There is an urgent need to develop predictive test methods better than animal experiments for assessing the safety of chemical substances to man. According to today's vision this is achieved by using human cell based tissue and organ models. In the new testing strategy the toxic effects are assessed by the changes in the critical parameters of the cellular biochemical routes (AOP, adverse toxic outcome pathway-principle) in the target tissues. In vitro-tests are rapid and effective, and with them automation can be applied. The change in the testing paradigm is supported by all stakeholders: scientists, regulators and people concerned on animal welfare.

Published
2013

2. [In vitro methods and safety testing of chemicals].

Author

Louekari K, Salminen L, and Tähti H

Subjects
Animal Testing Alternatives economics, Carcinogenicity Tests methods, European Union, Eye drug effects, Humans, In Vitro Techniques, International Cooperation, Irritants toxicity, Lethal Dose 50, Mutagenicity Tests methods, Reproducibility of Results, Animal Testing Alternatives methods, Inorganic Chemicals toxicity, Organic Chemicals toxicity, Safety legislation & jurisprudence, Toxicity Tests methods
Published
1998

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