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10 results on '"Ludes, Bertrand"'

3. Estimation de l'âge civil de garçons âgés de 12,5 à 16 ans Prediction of teenager's age from 12,5 to 16 years old

Author

pineau, jean-claude, Ludes, Bertrand, Biologie, anthropologie, biométrie, épigénétique, lignées : De la diversité des populations à l'individu, de l'identification à l'identité (BABEL - FRE 2029), and Université Paris Descartes - Paris 5 (UPD5)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SHS.ANTHRO-BIO]Humanities and Social Sciences/Biological anthropology, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018

6. Caractérisation de l’altération osseuse post-mortem par histomorphologie dans un contexte médico-légal : étude taphonomique sur restes humains

Author

Delannoy, Yann, Cannet, Catherine, Louria, Claire, Penel, Guillaume, Colard, Thomas, and Ludes, Bertrand

Subjects
FOS: Biological sciences
Abstract

L’altération d’un os en période post-mortem, est à l’origine d’une détérioration identifiable en histologie. La dégradation de l’os se caractérise notamment par une altération collagénique observable précocement. Dans le but de pouvoir caractériser cette altération, deux côtes ont été prélevées sur 6 corps humains et étudiées prospectivement pendant les 2 ans suivant le décès. Chaque os a fait l’objet d’une coupe histologique étudiée après coloration au rouge Sirius afin de mettre en évidence la dégradation du collagène en fonction du temps. Une altération osseuse temporelle a pu être mise en évidence par une dégradation architecturale de l’os lamellaire, en l’absence de toute attaque microbienne sur cette période post-mortem. La coloration pratiquée à l’aide du rouge Sirius a permis d’attribuer cette altération à une dégradation collagénique de type hydrolyse chimique en raison de l’affinité de ce colorant pour les acides aminés Lysine, Hydroxylysine et Arginine. Notre travail a permis d’affirmer que des échantillons osseux humains étudiés en environnement contrôlé, et analysés pendant 24 mois, subissent une trajectoire diagénétique dont l’élément principal est l’hydrolyse collagénique., The diagenesis of a bone in the post-mortem period causes an identifiable deterioration in histology. More particularly, the degradation of the bone is characterized by a collagenous alteration which is observable very early. In order to be able to characterize this alteration, two ribs collected from 6 human bodies were studied prospectively during 2 years. Each bone was studied after staining with red Sirius in order to demonstrate the degradation of collagen as a function of time. A temporal bone alteration could be demonstrated by an architectural degradation of the lamellar bone in the absence of any microbial attack on this post-mortem period. The coloring carried out using red Sirius correlated this alteration to a collagenic degradation by chemical hydrolysis because the affinity of this colorant to the amino acids Lysine, Hydroxylysine and Arginine. Our work asserts that human bone samples studied in controlled environment, and analyzed for 24 months, undergo a diagenetic trajectory whose main element is collagen hydrolysis.

Published
2017
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7. Amélioration continue du DES de biologie médicale à l’aide d’un carnet de stage et d’un questionnaire d’évaluation de la satisfaction. [= Clinical laboratory medicine: continuous amelioration with a book of objectives and satisfaction survey]

Author

Reix, Nathalie, Agin, Arnaud, Bahram, Seiamak, Dali-Youcef, Nassim, Grucker, Daniel, Jaulhac, Benoit, Lepiller, Quentin, Lessinger, Jean-Marc, Mauvieux, Laurent, Monier, Laurie, Schramm, Frederic, Stoll-Keller, Françoise, Vallat, Laurent, Ludes, Bertrand, Candolfi, Ermanno, Filisetti, Denis, Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), École Nationale du Génie de l'Eau et de l'Environnement de Strasbourg (ENGEES)-Université de Strasbourg (UNISTRA)-Institut National des Sciences Appliquées - Strasbourg (INSA Strasbourg), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de Recherche en Informatique et en Automatique (Inria)-Les Hôpitaux Universitaires de Strasbourg (HUS)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Immuno-Rhumatologie Moléculaire, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Bioimagerie et Pathologies (LBP), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Anthropologie Moléculaire et Imagerie de Synthèse (AMIS), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Dynamique des interactions Hôte pathogène, Université de Strasbourg (UNISTRA), Institut National des Sciences Appliquées - Strasbourg (INSA Strasbourg), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS)-École Nationale du Génie de l'Eau et de l'Environnement de Strasbourg (ENGEES)-Réseau nanophotonique et optique, Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Matériaux et nanosciences d'Alsace (FMNGE), Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Strasbourg (UNISTRA), and Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)

Subjects
book of objectives, objectives, satisfaction survey, improvement, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, medical biology training
Abstract

We report in this publication the use of two educational tools, a questionnaire of satisfaction and a training book, to improve the training of students during their internship in clinical laboratory at the "Pôle de biologie des Hôpitaux universitaires de Strasbourg" in France. First, the ongoing training was assessed by the interns with a questionnaire measuring satisfaction. The analysis of this questionnaire identified four key points to improve: 1) define the teaching objectives, 2) organize the training with a schedule, 3) revise certain teaching methods and 4) ensure better integration of the students in the team of medical biologists. After this assessment, we implemented a training book to answer these four points. Indeed, the training book presents the objectives, the schedule of training, and how to validate the educational objectives. A new assessment was performed again using the same methodology. Results showed an improvement in student satisfaction from 74 to 88 %. The questionnaire of satisfaction and the training book are presented in this article. The aim of the assessment of training combined with the training book is to incite the actors of the training (students and teachers) to continually improve the training. The objectives of the Pôle de Biologie are to obtain an 80 % satisfaction rate during the 6 months trainings and to reduce or eliminate dissatisfaction, and finally to ensure the validation by students of 80 to 100 % of their predetermined objectives.

Published
2015

8. Les auteurs

Author

Savall, Frédéric, Hérin, Fabrice, Alunni, Véronique, Bartoli, Christophe, Bascou, Agathe, Bouvet, Renaud, Dufayet, Laurène, Epain, Marie, Fanton, Laurent, Farrugia, Audrey, Francioni, Sophie, Grill, Stéphane, Jousset, Nathalie, Lefevre, Thomas, Ludes, Bertrand, Manaouil, Cécile, Moutel, Grégoire, Nahmani, Isabelle, Nohales, Ludivine, Peyron, Pierre Antoine, Rouge-Maillart, Clotilde, Scolan, Virginie, Tournel, Gilles, Tuchtan, Lucile, Andujar, Pascal, Baldi, Isabelle, Bensefa-Colas, Lynda, Esquirol, Yolande, Fontana, Luc, Gehanno, Jean-François, Gernigon, Caroline, Gislard, Antoine, Hulo, Sébastien, Lehucher-Michel, Marie-Pascale, Lesage, François-Xavier, Maître, Anne, Pairon, Jean-Claude, Rollin, Laëtitia, Sari-Minodier, Irène, Soulat, Jean-Marc, Thaon, Isabelle, and Villa, Antoine

Published
2022
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9. [DNA Ancestry and phenotype markers analyses and French law].

Author

Ludes B

Subjects
DNA, Ancient isolation & purification, Ethics, Medical, Female, France, Genetic Testing legislation & jurisprudence, History, Ancient, Humans, Legislation as Topic, Male, Phenotype, Phylogeny, Polymorphism, Single Nucleotide, DNA, Ancient analysis, Forensic Anthropology legislation & jurisprudence, Forensic Anthropology methods, Genetic Markers, Pedigree
Abstract

Since some of the genetic markers involved in the analyses are single nucleotide polymorphisms located in protein-coding regions or exons, their analyses are today forbidden for forensic application in French law. A recent application of the French Criminal Chamber of "Cour de Cassation" indicates that it would be possible to perform phenotypic studies and Ancestry Informative Markers (AIM) analysis on stain samples but not on samples taken from a body. The authors present the results of the HIrisplex test performed on seven bone samples belonging to a Mongolian Altaï population dated from the late Bronze Age. On account of the obtained results, the authors raise the question of the use of HIrisplex test on corpses and on skeletonized human remains for their identification.

Published
2016

10. [Clinical laboratory medicine: continuous amelioration with a book of objectives and satisfaction survey].

Author

Reix N, Agin A, Bahram S, Dali-Youcef N, Grucker D, Jaulhac B, Lepiller Q, Lessinger JM, Mauvieux L, Monier L, Schramm F, Stoll-Keller F, Vallat L, Ludes B, Candolfi E, and Filisetti D

Subjects
Education methods, Goals, Job Satisfaction, Quality Improvement, Records, Surveys and Questionnaires, Education standards, Medical Laboratory Science education
Abstract

We report in this publication the use of two educational tools, a questionnaire of satisfaction and a training book, to improve the training of students during their internship in clinical laboratory at the "Pôle de biologie des Hôpitaux universitaires de Strasbourg" in France. First, the ongoing training was assessed by the interns with a questionnaire measuring satisfaction. The analysis of this questionnaire identified four key points to improve: 1) define the teaching objectives, 2) organize the training with a schedule, 3) revise certain teaching methods and 4) ensure better integration of the students in the team of medical biologists. After this assessment, we implemented a training book to answer these four points. Indeed, the training book presents the objectives, the schedule of training, and how to validate the educational objectives. A new assessment was performed again using the same methodology. Results showed an improvement in student satisfaction from 74 to 88 %. The questionnaire of satisfaction and the training book are presented in this article. The aim of the assessment of training combined with the training book is to incite the actors of the training (students and teachers) to continually improve the training. The objectives of the Pôle de Biologie are to obtain an 80 % satisfaction rate during the 6 months trainings and to reduce or eliminate dissatisfaction, and finally to ensure the validation by students of 80 to 100 % of their predetermined objectives.

Published
2015
Full Text
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