1. [Comparison of the effects of xylazine and romifidine administered perioperatively on the recovery of anesthetized horses].
- Author
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Bauquier SH and Kona-Boun JJ
- Subjects
- Anesthesia Recovery Period, Anesthetics, Combined administration & dosage, Animals, Arthroscopy veterinary, Blood Gas Analysis veterinary, Blood Pressure drug effects, Blood Pressure physiology, Diazepam administration & dosage, Double-Blind Method, Female, Horses surgery, Ketamine administration & dosage, Male, Prospective Studies, Time Factors, Anesthesia, Intravenous veterinary, Horses physiology, Imidazoles administration & dosage, Perioperative Care veterinary, Xylazine administration & dosage
- Abstract
Comparison of the effects of xylazine and romifidine administered perioperatively on the recovery of anesthetized horses. The present study was designed to compare recoveries from anesthesia following the use of romifidine or xylazine in horses. In a prospective blind randomized clinical trial, 28 horses, undergoing elective arthroscopy, were randomly allocated into 2 groups. The intravenous anesthesia protocol used in the xylazine group was: butorphanol [0.02 mg/kg body weight (BW)] and xylazine (0.5 to 0.7 mg/kg BW) for premedication, diazepam (0.1 mg/kg BW) and ketamine (2.2 mg/kg BW) for induction, isoflurane in oxygen for maintenance and xylazine (0.1 mg/kg BW) in recovery. The xylazine was replaced with romifidine 0.05 to 0.08 mg/kg BW (premedication) and 0.01 mg/kg BW (recovery) in the romifidine group. The quality of recovery was evaluated with a modified scoring system and the duration recorded. Wilcoxon Ranked Sum test (P < 0.05) was used for statistical analysis. The recovery quality scores and the durations of recovery were not statistically different between the 2 groups. In this study, romifidine and xylazine were equal in their effects on recovery qualities.(Translated by the authors).
- Published
- 2011