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Many studies have investigated the causes of discontinuation during intraconjugal medically assisted procreation. However, there are currently very few data justifying the causes of discontinuation during the oocyte donation program. The main objective of this study is to determine the causes of discontinuation in oocyte donation and their respective frequency, excluding live births by oocyte donation in our center.This is an observational, retrospective, single-center study focused on receiving or requesting couples who stopped their oocyte donation program between January 1, 2005 and April 29, 2021. A total of 390 couples were included in the study.Of the 390 couples included, 306 couples or nearly 80%, left our oocyte donation program without obtaining a live birth through this method. The three most frequent reasons for discontinuation were: failure of several oocyte donations (18%), desire of the couples to voluntarily discontinue their care (15%) and separation (14%). Finally, 84 couples obtained at least one live birth by oocyte donation in our center. In addition, 38 women conceived spontaneously and 33 couples benefited from an oocyte donation abroad.The most common reason for discontinuation in oocyte donation program, excluding live births by oocyte donation in our center, is failure after several oocyte donations. However, 40% of the couples in the study obtained at least one live birth.

The current conditions of gamete donation in france. Law of bioethics and assisted reproductive technology legislation control gamete donation in France. Candidates for the gamete donation are still too few to date, not allowing to meet the needs of couples receiving gametes on French territory. This shortage leads to significant waiting times for these couples. The information provided to the candidates of gamete donation (oocytes and spermatozoa) is channeled through general practitioners as foreseen by the law. A good knowledge of recruitment rules for candidates and of the attribution conditions of the gamete donations allows the practitioners to disseminate the information and to support the recruitment of new candidates.Conditions actuelles du don de gamètes en France. Le don de gamètes en France est réglementé par la loi de bioéthique ainsi que par le guide de bonne pratique en assistance médicale à la procréation. Les candidats au don de gamètes sont à ce jour encore trop peu nombreux, ne permettant pas de répondre aux besoins des couples receveurs de don de gamètes sur le territoire français. Cette pénurie entraîne des délais d’attente importants pour ces couples. L’information des candidats au don de gamètes (ovocytes et spermatozoïdes) passe par les médecins traitants comme le prévoit la loi. Une bonne connaissance des règles de sélection des candidats ainsi que des conditions d’attribution des dons de gamètes permet aux praticiens de diffuser l’information et d’aider au recrutement de nouveaux candidats.