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Systemic sclerosis is an autoimmune disease characterized by vasculopathy and tissue fibrosis. Esophageal disorders are often associated. The diagnosis is confirmed and characterized by high-resolution esophageal manometry (HRM). This study aims to describe the esophageal motility disorders found by high-resolution esophageal manometry, in patients followed for systemic sclerosis. An observational study carried out between April 2018 and January 2020, including 23 patients with systemic sclerosis according to EULAR/ACR 2013 criteria, referred for high-resolution esophageal manometry. We used the Chicago V3.0 classification to order esophageal motor disorders into two categories: major and minor disorders of peristalsis. Four parameters were analyzed: lower esophageal sphincter resting pressure (LES), distal latency (DL) and distal contractile integral (DCI) and integrated relaxation pressure (IRP). IRP was normal in all cases. The digestive symptoms were: gastroesophageal reflux in 10 cases (43.4%) and dysphagia in 6 cases (26.2%). Seven patients were asymptomatic (30.4%). HRM revealed a major disorder of esophageal peristalsis in 14 cases (60.9%), minor disorders in 4 patients (17.4%) and was normal in 5 cases (21.7%). There was; hypotonia of the lower esophageal sphincter (LES) with absent contractility in 8 cases (44.5%), only absence of contractility in 6 cases (33.3%), hypotonia of the lower esophageal sphincter (LES) with ineffective motility in 4 cases (22.2%). High-resolution esophageal manometry should be considered in all patients with systemic sclerosis even in the absence of digestive symptoms. In our series, motility disorders were present in 78.3% of cases.