1. Stimulation of spermatogenesis: For whom? Why? How?
- Author
-
Didier Dewailly, J.-M. Rigot, Sophie Catteau-Jonard, Geoffroy Robin, J. Bertrand-Delepine, C. Leroy, Laboratoire de recherche en Hydrodynamique, Énergétique et Environnement Atmosphérique (LHEEA), École Centrale de Nantes (ECN)-Centre National de la Recherche Scientifique (CNRS), Gamétogenèse et Qualité du Gamète - ULR 4308 (GQG), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Université de Lille, and Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)
- Subjects
0301 basic medicine ,Infertility ,medicine.medical_specialty ,Infertilité masculine ,Pulsatile flow ,Semen ,Stimulation ,Citrate de clomifène ,Stimulation of spermatogenesis ,Pulsatile GnRH therapy ,Male infertility ,03 medical and health sciences ,0302 clinical medicine ,Hypogonadotropic hypogonadism ,Internal medicine ,Pompe à GnRH ,medicine ,Hypogonadotropic-hypogonadism ,Stimulation de la spermatogenèse ,ComputingMilieux_MISCELLANEOUS ,Gynecology ,030219 obstetrics & reproductive medicine ,business.industry ,Obstetrics and Gynecology ,Gonadotrophines ,[SDV.BDLR]Life Sciences [q-bio]/Reproductive Biology ,General Medicine ,Clomifene citrate ,medicine.disease ,3. Good health ,Hypogonadisme hypogonadotrope ,030104 developmental biology ,Endocrinology ,Reproductive Medicine ,business ,Spermatogenesis ,Gonadotropins - Abstract
The stimulation of spermatogenesis is the best treatment of infertility for male hypogonadotropic-hypogonadism. The results are very pleasing because a real improvement of semen is sometimes obtained with spontaneous pregnants describing in the literature but after a long duration of treatment, often many months. Sometimes, the treatment improves the technical conditions of ICSI for the embryologists. Stimulation of spermatogenesis by gonadotrophins rFSH and/or hCG is the most used but others treatments, like pulsatile GnRH therapy or clomifene citrate can be used. The purpose of this review is to described the different protocols of stimulation of spermatogenesis and explain their results and finally to see if others indications of stimulation of spermatogenesis are existing.
- Published
- 2016