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3. [Forefoot gangrene and infra-crural bypass: simultaneous amputation]

Author

M J, Jacobs

Subjects
Femoral Artery, Gangrene, Time Factors, Humans, Forefoot, Human, Amputation, Surgical, Blood Vessel Prosthesis, Retrospective Studies
Abstract

Patients presented for amputation mostly have chronic limb ischaemia caused by atherosclerosis, with signs of severe arterial insufficiency including rest pain, non-healing skin lesions, ulceration or gangrene. Foot infections, especially in diabetic patients, are often multimicrobial, deeply invasive and frequently require aggressive measures, like debridement and drainage or partial open forefoot amputation in addition to broad-spectrum antibiotics, in patients with critical limb ischaemia and limited necrosis and forefoot gangrene, distal bypass surgery is the treatment of choice. The main question is whether amputation should be performed simultaneously or in a secondary stage. Our own experience deals with 342 femorocrural and femoropedal bypass grafts for the treatment of critical limb ischaemia. The results showed no significant difference in graft patency between crural and pedal grafts. Clinical factors like diabetes mellitus, poor distal run-off and site of the distal anastomosis had no adverse effect on the functioning and patency of the graft. In this series we found that in diabetic patients significantly more amputations were required because of persistent foot infection. Since in these patients amputation was performed in a secondary stage, we changed our policy to simultaneous amputation. After completion of the bypass, closure and coverage of all the wounds, the gangrenous part is amputated. In case of deep, wet or infectious gangrene of the forefoot, an open transmetatarsal amputation is performed. Using this approach we have further increased limb-salvage and especially the number of usuable limbs.

Published
1996

4. A PRELIMINARY QUALITATIVE AND QUANTITATIVE STUDY OF THE MICROSCOPIC STRUCTURE OF THE DORSAL FAT BODY IN ADULT HONEYBEES (APIS MELLIFERA L.), INCLUDING A TECHNIQUE FOR THE PREPARATION OF WHOLE SECTIONS

Author

Hilde Raes, Edith Mastyn, Frans J. Jacobs, and Revues Inra, Import

Subjects
0106 biological sciences, Fat body, Dorsum, [SDV.EE]Life Sciences [q-bio]/Ecology, environment, Histology, Anatomy, [SDV.BID]Life Sciences [q-bio]/Biodiversity, Biology, 010603 evolutionary biology, 01 natural sciences, [SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology, 010602 entomology, [SDV.EE] Life Sciences [q-bio]/Ecology, environment, Insect Science, [SDV.SA.SPA]Life Sciences [q-bio]/Agricultural sciences/Animal production studies, [SDV.BA.ZI] Life Sciences [q-bio]/Animal biology/Invertebrate Zoology, [SDV.SA.SPA] Life Sciences [q-bio]/Agricultural sciences/Animal production studies, ComputingMilieux_MISCELLANEOUS, [SDV.BID] Life Sciences [q-bio]/Biodiversity
Abstract

International audience

Published
1985

5. Membrane-bound iron-rich granules in fat cells and midgut cells of the adult honeybee (Apis mellifera L.)

Author

H. Raes, P.H. De Rycke, Frans J. Jacobs, W. Bohyn, and Revues Inra, Import

Subjects
0106 biological sciences, Membrane bound, Adipose tissue, Zoology, [SDV.BID]Life Sciences [q-bio]/Biodiversity, Biology, 01 natural sciences, 03 medical and health sciences, Organelle, medicine, [SDV.SA.SPA] Life Sciences [q-bio]/Agricultural sciences/Animal production studies, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, chemistry.chemical_classification, [SDV.EE]Life Sciences [q-bio]/Ecology, environment, 0303 health sciences, Histology, Midgut, Epithelium, Cell biology, [SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology, 010602 entomology, [SDV.EE] Life Sciences [q-bio]/Ecology, environment, medicine.anatomical_structure, Enzyme, chemistry, Insect Science, [SDV.SA.SPA]Life Sciences [q-bio]/Agricultural sciences/Animal production studies, Ultrastructure, [SDV.BA.ZI] Life Sciences [q-bio]/Animal biology/Invertebrate Zoology, [SDV.BID] Life Sciences [q-bio]/Biodiversity
Abstract

International audience

Published
1989

6. Améliorer la réglementation du cannabis médical au Canada pour mieux servir les patients pédiatriques.

Author

Huntsman RJ, Kelly LE, Alcorn J, Appendino JP, Bélanger RE, Crooks B, Finkelstein Y, Gilpin A, Lewis E, Litalien C, Jacobs J, Moore-Hepburn C, Oberlander T, Rassekh SR, Repetski AE, Rieder MJ, Shackelford A, Siden H, Szafron M, 't Jong GW, and Vaillancourt R

Abstract

Competing Interests: Intérêts concurrents: Richard Huntsman et Lauren Kelly sont coprésidents du Comité consultatif scientifique sur les produits de santé contenant du cannabis de Santé Canada; l’opinion du Comité n’est ni reflétée ni garantie dans cet article. Lauren Kelly détient une bourse Mitacs Accélération en partenariat avec Canopy Growth, sans lien avec le présent manuscrit. Juan Pablo Appendino déclare avoir reçu des honoraires de Pendopharm, Sunovion et UCB; il est également membre de comités ou de conseils de la Canadian League Against Epilepsy, de la Société canadienne de neurophysiologie clinique, de la Fédération des sciences neurologiques du Canada et de l’Académie ibéro-américaine de neurologie pédiatrique. Richard Bélanger fait partie du comité sur le cannabis de la Société canadienne de pédiatrie. Bruce Crooks indique avoir participé au comité de surveillance de la sécurité des données pour l’étude ReRAD et il est membre du comité consultatif pour la Nouvelle-Écosse et du comité consultatif médical de la fondation Rêves d’enfants Canada. Evan Lewis est conseiller médical bénévole auprès de JMCC Canada Corp. et déclare avoir reçu des honoraires de Spectrum Therapeutics. Alexander Repetski a occupé un poste de consultant bénévole auprès de Strainprint. Michael Rieder est membre du comité de surveillance de l’innocuité des médicaments pour une étude sur l’utilisation du cannabis médical pour traiter la céphalée chez l’enfant, et il est l’auteur principal du document de principes de la Société canadienne de pédiatrie sur le cannabis médical chez les enfants. Régis Vaillancourt déclare avoir reçu des honoraires de consultation de Harvest Medicine. Aucun financement n’a été versé pour la rédaction de ce manuscrit. Aucun autre intérêt n’a été déclaré.

Published
2021
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