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Two cases of spurious thrombocytopenia are reported, one induced by platelet satellitism and the other by platelet aggregation. These phenomena occur in vitro, only in the presence of EDTA and are linked with the presence of IgG in the patients' sera.

Two patients receiving parenteral cloxacillin treatment developed agranulocytosis. Upon discontinuation of the drug, the number of leukocytes rapidly returned to normal. It is likely that an immunologic mechanism may be implicated in this drug-induced blood dyscrasia.

Circulating immune complexes were measured by a radioimmunoassay specific for HB complexes in different clinical situations related to hepatitis B virus infection. The leukocyte migration inhibition test (LMIT) was performed simultaneously. Comparison with the clinical situation suggests that immune complexes are not responsible for the lesions, but that these lesions might be produced by the immunity demonstrated by the LMIT. A deficiency of this immunity is responsible for the persistence of infection. However, in chronic active hepatitis, LMIT is as deficient as in carriers and in this form of hepatitis the frequency and quantity of complexes are the highest: it is thus possible that in this case the lesions are nevertheless produced by the complexes.