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The connection between the types of potassium concentration and the ecogenesis of the studied groups of animals, with the degree of extreme conditions of breeding, with types of potassium in extreme conditions of breeding is known. In this regard, studies on autochthonous species of ungulates in the Subarctic are of great interest, the most numerous of which is the reindeer (Rangifer tarandus). Comparative analysis of the adaptive responses of NK and LK types at different levels of organization confirmed the presence of the adaptive advantage of animals characterized by a hereditarily high concentration of potassium in the blood in ecological-geographical zones with extreme environmental conditions. As a result of a study on domesticated reindeer, a clearly expressed dimorphism in the level of potassium in the blood was revealed, due to a genetically controlled high NK and low LK concentration. The average level of potassium in whole blood in the studied population of reindeer is 26.94 ± 0.56 meq/l with a variability of 24.61%. It was revealed that the average level of potassium content in whole blood by sex and age was distributed as follows: whales 22.97 - 25.80 meq/l at P> 0.05, castrate bulls had indicators significantly higher than 28.37 - 29.58 meq / l, at P> 0.05, the young showed intermediate indicators - 27.37 - 28.13 at P> 0.05. The intragroup variability in potassium content in whole blood ranged from 15.5 to 31.05%. It was found that in domestic reindeer the ratio of animals of the high-potassium (HK) type is 88.02% and of the lowpotassium (LK) type - 11.98%, while the gene frequencies for highpotassium animals are 0.9381.

Among the diseases of young cattle of non-contagious aetiology, an important place is occupied by the pathology of the digestive system. In particular, dyspepsia, casein-bezoar disease, colostrum toxicosis, and diarrhoea are characteristic of the above pathologies. A familiar name, acute digestive disorders, unites these diseases. That is why it is essential to correct the metabolism of calves. The aim of the study is to investigate the effectiveness of antenatal prophylaxis for acute digestive disorders in calves of the neonatal period with the addition of propylene glycol to the diet of cows during the transient period, which increases the amount of propionic acid in the rumen and chlorophyll, which affects lipid metabolism and prevents fatty liver infiltration and ketosis. It was determined that the addition of propylene glycol and Cholin-Chloridum to the diet of cows during the transient period influenced the change in the content of β-hydroxybutyrate (HTA) and the amount of ketone bodies in the blood of animals in the experimental group of animals. In the experimental group of animals, these indicators were lower in the control group, by 35% of β-hydroxybutyrate and 44% by the sum of ketone bodies. During the transient period, especially in the first months after calving, cows experience an energy deficit, so ketone bodies are formed to compensate for glucose deficiency. Since propylene glycol and Cholin- Chloridum increased the glucose concentration in the blood, the need for synthesising ketone bodies decreased.

The study examines the development determinants of the dairy industry, a major component of global and national food security. Regarding production and trade factors affecting the whole agro-industrial complex and the dairy industry of Ukraine, the leading indicators of dairy products' availability and provision level were determined, and their dynamics were analyzed. Ukraine's dairy product consumption sufficiency indicator was defined as one of the food security criteria. It has been established that the production determinants of the dairy industry under martial law include the profitability cost level of milk production, the milking herd's number, raw milk quality and sufficiency, and the use of fodder in milk production. Trade determinants are sale opportunities, the price level for raw milk, the affordability of dairy products, and the current Ukrainian legislation in the trade sector. The developed linear multifactor model of the dairy products turnover by retail chains' dependence on the dairy products consumption level, the average monthly wage level, the inflation level and imports indicates a close relationship between the determined factors and allows to analyze the prospects of the market and the dairy industry, as GFCI components.

The article deals with the identification of foreigners and stateless persons, problems of legal regulation of relations of the State Border Guard Service of Ukraine on collecting biometric data of persons, types of data subject to collection, processing, storage and administration. The problems existing in the mechanisms of collecting biometric data of foreigners and stateless persons, as well as issues of personal data protection are considered. An attempt was made to suggest changes to laws and regulations in the field of migration and border protection on the basis of empirical data. The goal is to investigate the mechanism of identification of foreigners and stateless persons during border control procedures at border crossing points (checkpoints) and at entry-exit checkpoints, as well as during administrative proceedings and to identify ways to improve the legal regulation of these procedures in the activities of the State Border Guard Service of Ukraine. The methods used in the research were the analysis and comparison of national legislation with the legislation of the European Union Member States and the Council of Europe (including the case law of the European Court of Human Rights) on biometric data. The questionnaire survey method enabled to obtain objective information about the border guards' awareness of personal data. The forecasting method was used to formulate proposals for amendments to the legislation to improve the organization of work processes in the activities of the State Border Guard Service of Ukraine when using IT systems. The research will enable to improve the procedure for collecting biometric data of foreigners and stateless persons by border guards, strengthen the capacity of the State Border Guard Service of Ukraine to combat illegal migration.

The study is devoted to the problem of analysing the activities of water management organizations. Such an analysis is an important component of water resources management since many important tasks (technological, environmental, economic, and others) are assigned to water management organizations. It is proposed to use ratings for a comprehensive assessment of the performance of budgetary water management organizations. This methodology involves the use of individual indicators of their activities, which can be grouped into blocks as well as combined into generalized indicators. The initial stage of rating the organization’s activity is its assessment by individual parameters that form the main components of the activity, such as financial, intellectual, personnel, technological, informational, environmental, etc. Based on these data, an integrated assessment of the level of performance of organizations is carried out. The rating result for a separate period is given. The gathered array of data for the year will more objectively reflect the performance of the organization than quarterly data. Dynamic analysis in the context of the years under study will also allow identifying changes that have occurred in the rating of water management organizations as a result of identifying reserves and implementing measures aimed at improving their performance.

Introduction. Melatonin, a potent antioxidant agent, is essential for glucose homeostasis. The objective of the study was to determine the influence of melatonin on basal levels of glucose in blood, activities of glucose-6-phosphatase in kidney and liver, pyruvate kinase in muscles and heart, content of glycogen in muscles and heart of rats with alloxan-induced diabetes. Materials and methods. Diabetes was induced in male Wistar rats by single intraperitoneal injection of alloxan monohydrates (170 mg/kg). Four days after diabetes induction, rats were divided into diabetic and melatonin-diabetic groups (10 mg/kg «Sigma» USA, daily and intraperitoneal for 14 days starting from the 5th day). Results. Melatonin injections caused normalization of the elevated serum glucose level in diabetic group of rats compared with basal glucose level before treatment. The activity of pyruvate kinase in muscle and heart tissue of diabetic animals was 45% and 63% less than in control groups, respectively. Regarding kidney and liver of diabetic rats, the activity of glucose-6-phosphatase was increased in average by 148% compared with control value. The glycogen content in the heart and skeleton muscles of diabetic animals was reduced in average by 20% compared with the control. Melatonin restored all these indexes back to normal level. Conclusions. These findings suggested that melatonin restored the events in Cori cycle by possible activation of glycolysis in skeletal and heart muscles and normalization of gluconeogenesis in liver and kidneys.

Background. Escherichia coli enteritis is one of the most common causes of diarrhea in developed countries and is caused usually by pathogenic strains of Escherichia coli. Objectives. To investigate the role of reactive response of polymorphonuclear neutrophilic granulocytes (NG) of peripheral blood in the systemic inflammatory response mechanisms of acute Escherichia enterocolitis (AEC), depending on genes polymorphism of heat shock proteins (HSP) family 70-2 (HSP70-2, 1267A®G) and interleukin 10 (IL-10, C-592A). Material and methods. The genes polymorphism was analysed by PCR based method in 95 patients with AEC and 30 healthy individuals. Clinical markers of immune disorders were evaluated after hematological indices, based upon an extended general clinical blood analysis, using verified formulas. Results. The endogenous intoxication severity did not depend reliably on genotypes of IL-10 gene (rs1800872), however it was significantly 23.68% (р=0.043) higher in GG-genotype carriers of HSP70-2 gene (rs1061581). The reduction of cellular reactivity by 14.71-19.08% (р

The relevance of the research lies in the need to analyze the situation in the higher education sector in terms of training highly qualified personnel. The purpose of the article is to analyze the conditions for educating the modern professional elite. When conducting the analysis, the authors relied on the data of sociological studies, as well as statistics of both Russian and international companies. When determining the key categories, the authors referred to the normative documents and opinions of leading scientists in the education sector. Forming the professional elite has been considered in detail on the example of the implementation of various forms of education, including distance learning. The methodological basis of the research was made up of theoretical methods, such as the synthesis method, used in the course of studying the problematic area of the higher education system, as well as a combination of descriptive and comparative and historical methods. Based on the conducted analysis, the authors have concluded that it is necessary to maintain an integral system of universal competencies, as well as to develop the experience of independent professional activity. The research justifies the need to continue the development of Russian higher education exactly in this direction.

Education and science play a key role in the vision and development of a fair, peaceful and sustainable society (global, continental, regional and national). Education is one of the crucial preconditions for the implementation of the UN global strategy “Transforming our world: the 2030 Agenda for Sustainable Development” (“Agenda 2030”). Agenda 2030 sets practical challenges for governments to transform the education system (Education for Sustainable Development). Developments in the field of artificial intelligence (AI), robotics and intelligent systems are developing rapidly right now, purely now bring benefits (and, at the same time – probable danger and harm), directly now – significantly determine our existence – and will soon determine even more. When universities argue that 4IR should be given strong and close attention, it means that they can no longer rely only on traditional forms of human thinking and imagination, but also need thinking that depends on algorithmic computations of machines or forms of technology. In this sense, 4IR has changed not only what we do and how we do it, but also who we have become. The mission of the universities of the XXI century is to form a developed personality, a person of high cultural level, who can act in a situation characterized by significant environmental risks. Educational institutions must be transformed and improved as institutions that must create and strengthen a safe, non-violent, inclusive and effective learning environment for all members of society. Which, in the end, will help to achieve success in cooperation at all levels – both in education and science, and in society in general.

This research focuses on the problem of water supply, and its solution requires scientific and practical approaches in environmental, engineering, economic and other fields. Practical recommendations to create an integrated water use system in Ukraine are based on the delimitation of its target subsystems. Special attention is paid to an integrated approach to water resources management, identification of key issues, clear conceptual modeling, strategy development, and production of ‘useful’ scientific information. It is important to study the role of coordinating government bodies in the field of water space monitoring. In particular, this mechanism involves the development of national program for monitoring the aquatic environment, the formation of budgets of all bodies and institutions; search for additional sources of funding and organizational methods. An important tool for improving the state of water resources is the implementation of international environmental standards and conventions. These strategic decisions are entrusted to the Ministries of Environment and other governing bodies. The use of software products generate significant amounts of data accumulated in various information banks. The main direction of the study is the concentration of information data in one key database. It will provide clear assess to the data aquatic environment and make analytical studies.

This paper focuses on the perceptions of sustainability and environmental protection expressed by the users of social networks (such as Facebook or WhatsApp). Forming the perception of climate change and environmental protection is a part of sustainable education. Social networks and Internet-based technologies might contribute to the process of gaining, processing and exchanging the information on sustainable development and to help to shape the social environmental awareness. Our results demonstrate that people who are familiar with the concept of sustainability consider environmental protection to be very important compared to those who are not familiar with this concept. In addition, it appears that people without any significant knowledge about sustainability are not interested in environmental protection. These outcomes suggest that sustainable education might help people in changing their perspectives and considering environmental protection to be essential for the future.

The article is concerned with the holistic approach to the study of the tourism potential of the South of Russia. The paper presents analyses of various techniques to the research of the tourist opportunities of territories both in Russia and in other countries. Methodological approaches are described in the study of the macroregions tourist potential. The assessment and ranking of the natural, cultural, and socio-economic potential of all administrative entities forming the South of Russia in terms of their importance for tourism have been carried out. The aggregate indicator of tourist and recreational potential of each entity has been calculated. Regions with a high level of tourist and recreational potential, relatively high, average, and relatively low are identified.

Este paper, produto da minha tese de doutoramento em História pela Unicamp (defendida em 2001 e publicada pela Boitempo em 2004), analisa o processo final do Departamento de Censura de Diversões Públicas (DCDP) e a atividade de seus dois últimos diretores-gerais: Solange Hernandez e Coriolano de Loyola Cabral Fagundes. O intuito é redesenhar o quadro que finaliza a Censura Federal a partir da atuação destes dois técnicos e seus laços políticoadministrativos.

O cerne da reflexão centra-se na análise do papel desempenhado pela maioria dos órgãos da grande imprensa nas vésperas do golpe de 1968, no pós AI-5 e, principalmente, na construção da memória dos “homens de jornal” no contemporâneo acerca de suas ações no passado recente do país.