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Your search keyword '"Leukemia, Myelomonocytic, Acute pathology"' showing total 5 results
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5 results on '"Leukemia, Myelomonocytic, Acute pathology"'

2. [Targeting oxidative metabolism to treat leukemia?].

Author

Callens C, Moura IC, and Hermine O

Subjects
Animals, Cell Differentiation drug effects, Drosophila Proteins physiology, Drosophila melanogaster cytology, Drosophila melanogaster metabolism, Hematopoietic Stem Cells cytology, Hematopoietic Stem Cells drug effects, Humans, Iron physiology, Iron Chelating Agents pharmacology, Leukemia, Myeloid, Acute metabolism, Leukemia, Myeloid, Acute pathology, Leukemia, Myelomonocytic, Acute metabolism, Leukemia, Myelomonocytic, Acute pathology, Models, Biological, Neoplasm Proteins antagonists & inhibitors, Neoplastic Stem Cells cytology, Neoplastic Stem Cells drug effects, Oncogene Proteins, Fusion antagonists & inhibitors, Oxidative Stress, Polycomb Repressive Complex 1, Signal Transduction drug effects, Signal Transduction physiology, Tretinoin therapeutic use, Vitamin D physiology, Iron Chelating Agents therapeutic use, Leukemia, Myeloid, Acute drug therapy, Leukemia, Myelomonocytic, Acute drug therapy, Reactive Oxygen Species antagonists & inhibitors
Published
2010
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3. [Genital ulcerations revealing an acute myelomonocytic leukaemia].

Author

Granel B, Serratrice J, Ene N, Vey N, Sainty D, Disdier P, and Weiller PJ

Subjects
Adult, Diagnosis, Differential, Female, Follow-Up Studies, Humans, Leukemia, Myelomonocytic, Acute complications, Prognosis, Time Factors, Leukemia, Myelomonocytic, Acute diagnosis, Leukemia, Myelomonocytic, Acute pathology, Leukemic Infiltration, Skin pathology, Ulcer etiology, Vulvar Diseases etiology
Published
2004
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4. [Langerhans cell histiocytosis and myelomonocytic leukemia: a non-fortuitous association].

Author

Baikian B, Descamps V, Grossin M, Marinho E, Picard C, Aitken G, Sigal M, Crickx B, and Belaich S

Subjects
Aged, Biopsy, Female, Hematopoietic Stem Cells pathology, Histiocytes pathology, Histiocytosis, Langerhans-Cell diagnosis, Histiocytosis, Langerhans-Cell pathology, Humans, Intertrigo pathology, Leukemia, Myelomonocytic, Acute diagnosis, Leukemia, Myelomonocytic, Acute pathology, Leukemia, Myelomonocytic, Chronic diagnosis, Leukemia, Myelomonocytic, Chronic pathology, Male, Risk Factors, Skin pathology, Histiocytosis, Langerhans-Cell genetics, Leukemia, Myelomonocytic, Acute genetics, Leukemia, Myelomonocytic, Chronic genetics
Abstract

Background: Langerhans cell histiocytosis is an uncommon clonal disorder. Its reactional or genetic nature is debated., Case Report: Three patients aged 71, 75 and 73 years with Langerhans cell histiocytosis also developed myelomoncytic leukemia (AML4, AML5, and chronic myelomonocytic leukemia). In two cases, there was no prior treatment which could potentially induce leukemia. In the third case, AML4 occurred shortly (10 months) after initiation of a vinblastin treatment., Discussion: This pathogenic association suggests a common origin for these two conditions, corresponding to an anomalous pluripotent stem cell line. These cases provide further evidence favoring the hypothesis of a genetic origin rather than a reactional origin for Langerhans cell histiocytosis.

Published
1999

5. [Acute myelomonocytic leukemia with eosinophils. Apropos of a case with a cytogenetic analysis and nosologic discussion].

Author

Battin J, Guérin-Darmendrail V, and Martin V

Subjects
Adolescent, Bone Marrow pathology, Chromosome Disorders, Eosinophils pathology, Granulocytes pathology, Humans, Leukemia, Myelomonocytic, Acute classification, Leukemia, Myelomonocytic, Acute genetics, Male, Chromosome Aberrations pathology, Chromosomes, Human, Pair 16, Leukemia, Myelomonocytic, Acute pathology
Abstract

Report of overwhelming leukemia with meningeal involvement in a 13-year-old. Cytologic and ultrastructural examinations showed features of myelomonocytic leukemia with abnormal eosinophils. The karyotype showed pericentric inversion of chromosome 16. Although these findings establish the diagnosis of acute myelomonocytic leukemia with abnormal eosinophils (M4Eo), this case ran an exceptionally severe course and exhibited some unusual cytologic features.

Published
1989

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