1. [Acquired isolated factor VII deficiency and bronchogenic carcinoma. A case report]
- Author
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Mohamed, Zili, Sadok, Hammami, Adel, Marghli, Lamia, Mechmech, Louisa, Boughnim, Salem, Abid, N'siri, Brahim, Nour El Houda, Toumi, Tarek, Kilani, and Sadok, Yaalaoui
- Subjects
Male ,Lung Neoplasms ,Factor VII Deficiency ,Humans ,Middle Aged - Abstract
An acquired factor VII deficiency was identified in a 63-year-old man with bronchogenic carcinoma. Initial studies indicated a normal activated partial thromboplastin time and a prolonged prothrombin time. The factor VII level was 6%. No evidence of a factor VII inhibitor or inactivator was demonstrable. However, on account of the initial normal laboratory test of emostases, the partial correction of the prothrombin time with 50% normal plasma in vitro and the family history, the congenital deficiency in factor VII was ruled out. Whatever the mechanism involved, this factor VII deficiency was related to malignancy.
- Published
- 2005