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Postprocedural myocardial necrosis as indicated by biomarkers increase is frequent after percutaneous coronary interventions (PCI) in up to 40% of cases. Pretreatment by statin could reduce the occurrence of those periprocedural myonecrosis. Medline and Cochrane Database screenings allow us to select articles published until March 2007. Sixteen prospective and retrospective studies have been identified in relation with the impact of statin pretreatment on periprocedural myonecrosis or morbimortality outcomes in patients who underwent PCI. Among selected studies, 12 provide the rate of periprocedural myocardial infarction. The relative risk (RR) of periprocedural myocardial necrosis in patients pretreated with statin was 0.50 (95% CI: 0.40-0.63). Among the 5409 patients with clinical follow-up ensured until six months, the RR of death in patients pretreated with statin before the PCI was 0.64 (95% CI: 0.44-0.93). Significant heterogeneity was observed in the results. In sensitivity analysis, stable and unstable patients were compared with similar RR reduction of periprocedural myonecrosis in favour of patients receiving statin before PCI. In the present meta-analysis, we confirm that statin pretreatment before PCI is able to reduce periprocedural myonecrosis and suggest a potential impact on six months survival of patients.

Summary. — The purpose of this paper is to suggest a statistical approach to the evaluation of long bone asymmetry and to encourage the use of simple indexes rather than raw measures. The study considered 101 individuals from the cemetery of Saint-Martin-de-Cognac (Charente, France) (VII^-XV* centuries). Maximum length and minimum shaft diameters of the five long bones (humeras, radius, ulna, femur and tibia) were taken. The lengths and circumferences of the lower limb bones are the variables which present the smallest lateral dominance. The analysis of the sexual dimorphism did not reveal any significant differences, but specific characteristics due to the division of physical activities in this population were brought to light. The estimation of asymmetry is evaluated more appropriately with indexes than with differences in measurements of left and right sides., Résumé. — L'objectif de cette étude est de proposer une démarche statistique permettant l'évaluation des asymétries des os longs en soulignant l'intérêt à utiliser des indices simples plutôt que des mesures brutes. L'enquête a porté sur 101 sujets de la nécropole de Saint-Martin-de-Cognac (Charente, France) (VIIe-XVe siècles). La longueur maximale et le périmètre minimum de cinq os longs (humérus, radius, ulna, fémur et tibia) ont été étudiés. Les longueurs et le périmètre des os des membres inférieurs sont les variables qui présentent la plus petite latéralisation. L'analyse du dimorphisme sexuel ne montre pas de différence significative et nous informe sur les particularités propres à la délégation des activités physiques de cette population. Les indices s'avèrent plus aptes, que les différences entre les mesures des côtés droit et gauche, à mettre en évidence une asymétrie., Sansilbano-Collilieux Montserrat, Morello Rémy. Méthodes d'évaluation des asymétries des membres : application à une population archéologique (Saint-Martin-de-Cognac, VIIe-XVe siècles). In: Bulletins et Mémoires de la Société d'anthropologie de Paris, Nouvelle Série. Tome 8 fascicule 3-4, 1996. pp. 451-463.