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Your search keyword '"Valerates pharmacology"' showing total 9 results
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9 results on '"Valerates pharmacology"'

1. [Effects of sodium n-dipropylacetate on the GABA level in various areas of the mouse brain].

Author

Simler S, Gensburger C, Ciesielski L, and Mandel P

Subjects
Animals, Caudate Nucleus metabolism, Cerebellum metabolism, Hippocampus metabolism, Hypothalamus metabolism, Medulla Oblongata metabolism, Mice, Olfactory Bulb metabolism, Pons metabolism, Aminobutyrates metabolism, Brain metabolism, Valerates pharmacology, Valproic Acid pharmacology, gamma-Aminobutyric Acid metabolism
Abstract

Regional brain GABA distribution studies show that after administration of sodium n dipropylacetate, a competitive inhibitor of GABA transaminase, the concentration of GABA increases in some regions i.e. Olfactory Bulbs, Hypothalamus, Cortex, Cerebellum. The GABA level remains unchanged in Caudate Nucleus, Pons Medulla, Hippocampus in our experimental conditions. These variations do not correlate with the initial GABA level.

Published
1976

2. [Comparison of the effects of di-n-propylacetate and oxazepam on spontaneous and conditioned responses in mice].

Author

Misslin R, Ropartz P, and Mandel P

Subjects
Animals, Dose-Response Relationship, Drug, Male, Mice, Avoidance Learning drug effects, Behavior, Animal drug effects, Oxazepam pharmacology, Valerates pharmacology, Valproic Acid pharmacology
Abstract

When effects of di-n-propylacetate (nDPA) on various patterns of behaviour in mice in "novel environment" tests are compared with the effects of oxazepam, it appears that the stimulating action of nDPA is more evident than its antianxiety effects. Learning seems to be facilitated by this stimulating action.

Published
1975

3. [Effects of n-dipropylacetate on cardiac frequency and emotionality in mice].

Author

Misslin R and Ropartz P

Subjects
Animals, Male, Mice, Emotions drug effects, Heart Rate drug effects, Valerates pharmacology, Valproic Acid pharmacology
Abstract

n-di-propylacetate (nDPA) reduced the heart rate level of Mice. Heart rate is often related to animal's emotionality. The nDPA would reduce the emotional behaviour.

Published
1976

5. [Hyperbaric oxygen: effect of sodium dipropylacetate and dipropylacetamine on convulsion seizures and pulmonary lesions in the mouse].

Author

Joanny P, Eymard P, Lacolle JY, Ferrandes B, and Corriol J

Subjects
Acetamides pharmacology, Animals, Mice, Pulmonary Edema etiology, Seizures etiology, Hyperbaric Oxygenation adverse effects, Pulmonary Edema prevention & control, Seizures prevention & control, Valerates analogs & derivatives, Valerates pharmacology, Valproic Acid analogs & derivatives, Valproic Acid pharmacology
Abstract

It was shown that oxygen at high pressure (OHP) induced epileptic seizures and pulmonary damages on mice. Dipropylacetate protected mice against nervous syndrome better than did dipropylacetamide. No significant pulmonary protection was observed with both drugs.

Published
1975

7. [Complementary pharmacological study of di-n-propylacetamide or depamide].

Author

Eymard P and Werbenec JP

Subjects
Amides pharmacology, Animals, Anticonvulsants pharmacology, Anxiety drug effects, Humans, Male, Motor Activity drug effects, Rats, Tranquilizing Agents pharmacology, Aggression drug effects, Behavior, Animal drug effects, Peptic Ulcer drug therapy, Valerates pharmacology
Published
1972

9. [Effects of broken-chain organic acids on the spontaneous and conditioned activities of the mouse].

Author

Misslin R, Sutter A, Ciesielski L, and Maitre M

Subjects
Acoustic Stimulation, Aminobutyrates pharmacology, Animals, Dose-Response Relationship, Drug, Injections, Intraperitoneal, Mice, Neurochemistry, Reinforcement, Psychology, Transaminases, Behavior, Animal drug effects, Caproates pharmacology, Conditioning, Classical drug effects, Movement drug effects, Valerates pharmacology
Published
1973

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