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On the basis of his results, obtained during a long term study of 32 patients presenting cyclic variations of mood with a known frequency, the author concludes that dipropylacetamide permits to stabilise mood in about 70% of all cases through a supression of relapses or by reducing significantly their frequency. No biological changes were observed and the clinical tolerance of the drug was excellent in most cases. This drug constitutes a variable alternative to lithium treatment, and lacks the well known lithium side effects and limitations.

In a division of the neuropsychiatric hospital of Racconigi, with acute and chronic inpatients, the use of 1-glutamine and N-dipropylacetic acid as subsidiary psychodrugs, after one year follow-up, showed to have reduced the whole administration of neuroleptics, without diminishing the therapeutic efficacity. This administration, during the four sampler months (December, March, June and September), face with the sames of the preceding year, has been lesser than 29,04% (lesser than 38,21%, if we take into consideration the last two months). Such result has been confirmed by a corresponding diminution of orphenadrine, the drug used to counteract the neuroleptic syndrome, which during the last two months considered in this research, respectively subsided of 28,57% and 36,36%.