278 results on '"CARDIOPULMONARY bypass"'
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2. Multiprofessionalität in der Herzmedizin: Perspektiven in der Perfusiologie und Technischen Medizin: Unde venis, quo vadis?
- Author
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Gehron, Johannes and Münch, Frank
- Abstract
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- Published
- 2025
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3. Die Effekte der Herz-Lungen-Maschine auf das intestinale Mikrobiom und die Relation zum postoperativen SIRS.
- Author
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Hinkov, Hristian, Markó, Lajos, Nazari-Shafti, Timo Z., Neuber, Sebastian, Meyborg, Heike, Krüger, Katrin, Forslund, Sofia K., Müller, Dominik N., Falk, Volkmar, Emmert, Maximilian Y., and Rodriguez, Héctor
- Abstract
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- Published
- 2023
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4. Infektiöse Endokarditis: Die Rolle von Entzündungsmediatoren und Komorbiditäten.
- Author
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Diab, Mahmoud, Franz, Marcus, Hamadanshi, Ali, Maschke, Almut, Faerber, Gloria, and Doenst, Torsten
- Abstract
Copyright of Zeitschrift für Herz-, Thorax- und Gefaesschirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
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5. Mechanische Herz-Kreislauf-Unterstützung : Indikationen, Systeme, Implantationstechniken
- Author
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Udo Boeken, Alexander Assmann, Frank Born, Christof Schmid, Udo Boeken, Alexander Assmann, Frank Born, and Christof Schmid
- Subjects
- Coronary circulation, Blood--Circulation, Artificial, Heart, Mechanical, Cardiopulmonary bypass
- Abstract
Im handlichen Taschenbuchformat gibt das Buch einen Überblick zum aktuellen Stand der mechanischen Herz-Kreislauf-Unterstützung. Die einzelnen verwendeten Systeme werden in Wort und Bild vorgestellt, ihre Besonderheiten und Einsatzmöglichkeiten hervorgehoben und die nationalen und internationalen Ergebnisse ihrer Anwendung zusammengefasst.
- Published
- 2013
6. Systemminimalisierung im Rahmen der extrakorporalen Zirkulation: Technische Möglichkeiten der Vermeidung EKZ-assoziierter pathophysiologischer Veränderungen.
- Author
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Bauer, Adrian, El-Essawi, Aschraf, Gehron, Johannes, Böning, Andreas, Harringer, Wolfgang, and Hausmann, Harald
- Abstract
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- Published
- 2020
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7. Level-IV-Cavathrombus : Eine seltene Diagnose bei Patienten mit Nierenzellkarzinom.
- Author
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Hofer, L., Gasch, C., Hatiboglu, G., Motsch, J., Grüllich, C., Duensing, S., Hohenfellner, M., and Grüllich, C
- Abstract
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- Published
- 2017
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8. Extrakorporale Unterstützungsverfahren bei Lungentransplantation.
- Author
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Schmack, B., Weymann, A., Zych, B., Sabashnikov, A., Grossekettler, L., Ruhparwar, A., Karck, M., Simon, A., and Popov, A.-F.
- Abstract
Copyright of Zeitschrift für Herz-, Thorax- und Gefaesschirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2017
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9. Extrakorporale Zirkulation.
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Liebold, A.
- Abstract
Copyright of Zeitschrift für Herz-, Thorax- und Gefaesschirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2015
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10. Mesenterialischämie bei selektiver Hirnperfusion.
- Author
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Haldenwang, P.L., Klein, T., Neef, K., Zeriouh, M., Riet, T., Sterner-Kock, A., Christ, H., Wahlers, T., and Strauch, J.T.
- Abstract
Copyright of Zeitschrift für Herz-, Thorax- und Gefaesschirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2014
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11. Pulmonale Embolektomie.
- Author
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Kramm, T., Guth, S., and Mayer, E.
- Abstract
Copyright of Zeitschrift für Herz-, Thorax- und Gefaesschirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2014
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12. Akzidentelle Hypothermie.
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Brugger, H., Putzer, G., and Paal, P.
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- *
ACCIDENTS , *HYPOTHERMIA treatment , *DECISION making , *BODY temperature , *HYPOTHERMIA , *EXTRACORPOREAL membrane oxygenation , *CARDIOPULMONARY bypass , *DIAGNOSIS - Abstract
Uncertainty exists on how to treat patients suffering from accidental hypothermia and on the optimal transport decisions. The aim of this review is to provide an updated evidence-based reference for the pre-hospital and in-hospital management of patients with accidental hypothermia and for the transport decisions required to facilitate treatment. Advances in the efficiency and availability of rewarming techniques have improved the prognosis for patients presenting with hypothermia. For hypothermic patients with a core body temperature ≥ 28 °C without cardiac instability there is increasing evidence to support the use of active external and minimally invasive rewarming techniques (e.g. chemical, electrical or forced air heating packs, blankets and warm parenteral fluids). Hypothermic patients with cardiac instability (i.e. systolic blood pressure < 90 mmHg, ventricular arrhythmia and core body temperature < 28 °C) should be rewarmed with active external and minimally invasive rewarming techniques in a hospital which also has circulation substituting venous-arterial extracorporeal membrane oxygenation (VA-ECMO) and cardiopulmonary bypass (CBP) facilities. In cardiac arrest patients VA-ECMO may be a better treatment option than CBP and survival rates of 100 % can be achieved compared to ~ 10 % with traditional methods (e.g. body cavity lavage). Early transport to a hospital appropriately equipped for rewarming has the potential to decrease complication rates and improve survival. [ABSTRACT FROM AUTHOR]
- Published
- 2013
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13. Inhalatives Kohlenmonoxid zur Protektion der Lunge während des kardiopulmonalen Bypasses.
- Author
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Schibilsky, D., Göbel, U., Siepe, M., Beyersdorf, F., Loop, T., and Schlensak, C.
- Abstract
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- Published
- 2013
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14. Kardiopulmonaler Bypass in der Herzchirurgie.
- Author
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Baehner, T., Boehm, O., Probst, C., Poetzsch, B., Hoeft, A., Baumgarten, G., and Knuefermann, P.
- Subjects
- *
CARDIOPULMONARY bypass , *CARDIAC surgery , *IMMUNE response , *INFLAMMATION , *MECHANICAL hearts , *INDUCED cardiac arrest , *ARTIFICIAL blood circulation - Abstract
Cardiopulmonary bypass (CPB) is a standard procedure in cardiac surgery; however, apart from its therapeutic options a CPB might also initiate systemic and organ-specific complications, such as heart failure, renal and pulmonary dysfunction, impaired coagulation as well as neurological and cognitive dysfunction. The immunological response to the extracorporeal circulation generates systemic inflammation which often meets the definition of systemic inflammatory response syndrome (SIRS). The main inducers of SIRS are contact of blood with the artificial surfaces of the CPB, mechanical stress which affects the blood components and the extensive surgical trauma. Hence, a number of technical and surgical developments aim at reduction of the inflammatory response caused by the CPB. By reason of surgical demands, the majority of cardiothoracic procedures still depend on the use of CPB; however, there is an on-going development of new techniques trying to reduce the surgical trauma and the negative consequences of CPB. Here, minimized systems with biocompatible surfaces have been shown to be effective in attenuating the inflammatory response to CPB. Alternative procedures such as off-pump surgery may help to avoid CPB-associated complications but due to specific limitations will not replace conventional bypass surgery. [ABSTRACT FROM AUTHOR]
- Published
- 2012
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15. Psychomotorische Entwicklung von Kindern mit angeborenem Herzfehler.
- Author
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Hövels-Gürich, H.H.
- Abstract
Copyright of Monatsschrift Kinderheilkunde is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2012
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16. Hochrisikolungenembolie.
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Kalbhenn, J., Loop, T., and Stahl, C.A.
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PULMONARY embolism , *BLOOD circulation disorders , *CARDIOPULMONARY bypass , *SURGICAL therapeutics , *TOMOGRAPHY , *ECHOCARDIOGRAPHY , *CARDIOPULMONARY resuscitation , *WOMEN patients , *EMBOLISM risk factors - Abstract
High risk pulmonary embolism commonly presents with a variety of symptoms and is an acute life-threatening event. In patients showing unclear acute circulatory distress, pulmonary embolism should be quickly ruled out by computed tomography or echocardiography. The diagnostic steps and surgical treatment of pulmonary embolism in a 25-year-old female patient suffering from acute circulatory insufficiency resulting in cardiac arrest within 11 min after emergency hospital admission are reported. Due to the reasonable suspicion of acute right heart decompensation, systemic perfusion was re-established by cardiopulmonary bypass after cardiopulmonary resuscitation for 41 min. Sternotomy and surgical embolectomy were performed. The patient was successfully extubated the following day and despite the long resuscitation time the outcome was excellent without any neurological deficit. Recent publications addressing the advantages of primary embolectomy versus intravenous thrombolysis in acute circulatory distress caused by pulmonary embolism are discussed. Primary surgical treatment including cardiopulmonary bypass for right ventricular relief and re-establishing of systemic perfusion is recommended for patients with pulmonary embolism undergoing cardiopulmonary resuscitation. [ABSTRACT FROM AUTHOR]
- Published
- 2011
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17. Kognitive Störungen nach kardiochirurgischen Eingriffen.
- Author
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Schwarz, N., Schönburg, M., Kastaun, S., Gerriets, T., and Kaps, M.
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NEUROLOGY , *ISCHEMIA , *CARDIAC surgery , *NEUROPSYCHOLOGY - Abstract
Over 100,000 heart surgeries are performed in Germany annually. Although severe neurological complications like ischaemic strokes have meanwhile become rare occurrences, subtle neuropsychological changes are still frequently recognized after major heart surgeries. The hitherto unsolved problem of postoperative cognitive decline (POCD) is portrayed in this article. Multifactorial aetiologies including microembolism and preoperative risk factors are supposed to play a significant role in POCD. A variety of neuroprotective strategies such as intraoperative microemboli filtration have been suggested to minimize cerebral risks. The utility of neuroprotective methods has recently been verified in randomized studies. [ABSTRACT FROM AUTHOR]
- Published
- 2011
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18. Reduktion von perioperativer Letalität und Morbidität in der Koronarchirurgie mit Clampless-off-pump-Technik.
- Author
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Börgermann, Jochen, Kuss, O., Hakim, K., Renner, A., Parsa, A., Aboud, A., Becker, T., Mirow, N., Zittermann, A., and Gummert, J.F.
- Abstract
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- Published
- 2011
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19. Antiinflammatorische Effekte von Pentoxifyllin.
- Author
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Groesdonk, H. V., Heringlake, M., and Heinze, H.
- Abstract
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- Published
- 2010
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20. Antiinflammatorische Effekte von Pentoxifyllin.
- Author
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Groesdonk, H.V., Heringlake, M., and Heinze, H.
- Subjects
- *
RHEOLOGY , *CEREBROVASCULAR disease , *PENTOXIFYLLINE , *CARDIAC surgery , *ISCHEMIA , *REPERFUSION injury - Abstract
Initially introduced as a rheologic agent for use in intermittent claudication due to peripheral artery disease and in ischemic cerebrovascular disease, the methylxanthine derivative pentoxifylline (PTX) has been shown to possess several anti-inflammatory properties which make this drug an interesting immunomodulating adjunct for the management of patients undergoing cardiac surgery. As an unspecific phosphodiesterase inhibitor PTX ameliorates the inflammatory response following a septic stimulus and blunts organ dysfunction after ischemia-reperfusion injury. Apart from this several small clinical studies have shown that the use of PTX may blunt the inflammatory response induced by cardiac surgery using a cardiopulmonary bypass. Additionally it has been shown that the perioperative application of this drug may improve postoperative function of organs at risk, such as the kidneys and liver. [ABSTRACT FROM AUTHOR]
- Published
- 2009
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21. Linksventrikuläre diastolische Dysfunktion.
- Author
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Meierhenrich, R., Schütz, W., and Gauss, A.
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ECHOCARDIOGRAPHY , *DOPPLER echocardiography , *DOPPLER ultrasonography , *SEPSIS , *CARDIOPULMONARY bypass - Abstract
Over the last two decades there has been a growing recognition that cardiac function is not solely determined by systolic but also essentially by diastolic function. Left ventricular diastolic dysfunction is characterized by an impairment of ventricular filling caused either by abnormal relaxation, an active energy consuming process or decreased compliance, which is determined by passive tissue properties of the ventricle. Doppler echocardiography, including tissue Doppler imaging, has emerged as the preferred clinical tool for the assessment of left ventricular diastolic function. Recently the importance of left ventricular diastolic function is increasingly being recognized also during the perioperative period. Newer studies have shown that after cardiopulmonary bypass there is a significant decrease in left ventricular compliance. Experimental studies have demonstrated that sepsis is associated with a decrease in both active relaxation and ventricular compliance. Initial studies are also focusing on therapeutic options for patients with isolated diastolic dysfunction. [ABSTRACT FROM AUTHOR]
- Published
- 2008
- Full Text
- View/download PDF
22. Chirurgische Koronarrevaskularisation am schlagenden Herzen.
- Author
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Rastan, Ardawan Julian, Walther, Thomas, Falk, Volkmar, Lehmann, Sven, Kempfert, Jörg, and Mohr, Friedrich Wilhelm
- Subjects
CORONARY artery bypass ,CARDIOPULMONARY bypass ,CARDIOMYOPATHIES ,HEART disease risk factors ,MORTALITY - Abstract
Copyright of Herz is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2007
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23. Der Anästhesiologische Nachbefragungsbogen für Patienten in der Herzanästhesie. Ergebnisse einer Multizentererhebung des wissenschaftlichen Arbeitskreises Kardioanästhesie der Deutschen Gesellschaft für Anästhesiologie und Intensivmedizin.
- Author
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Hüppe, M, Zöllner, M, Alms, A, Bremerich, D, Dietrich, W, Lüth, J-U, Michels, P, and Schirmer, U
- Subjects
ANESTHESIA ,ANESTHESIOLOGY ,CARDIOPULMONARY bypass ,COMPARATIVE studies ,CARDIAC surgery ,PROSTHETIC heart valves ,RESEARCH methodology ,MEDICAL cooperation ,PATIENT satisfaction ,QUESTIONNAIRES ,RESEARCH ,RESEARCH evaluation ,SURGICAL complications ,EVALUATION research ,ACQUISITION of data - Abstract
Objective: The Anaesthesiological Questionnaire (ANP) is a self-rating method for the assessment of postoperative complaints and patient satisfaction. The questionnaire was adapted for use in cardiac anaesthesia (ANP-KA). The study was conducted to show the value of ANP-KA as a practicable means of assessing the patient's state after cardiac anaesthesia and for its use in quality assurance.Methods: A total of 1,688 patients from 19 clinics were included who had exclusively received heart valve surgery, CABG surgery or both operations. They completed the ANP-KA between days 1 and 8 postoperatively.Results: The ANP-KA was completed by 79.1% of the patients without any assistance. The highest incidence rates were reported for a dry mouth/thirst (85.1%) and for pain in the area of surgery (60.2%). Plausible and significant differences in patients' symptoms between the grading for the immediate postoperative period and the current state at filling in the questionnaire were found. Women reported more postoperative complaints than men but no differences were found between male and female patients with regard to satisfaction with anaesthesiological care and convalescence. More complaints were reported after heart valve surgery than after CABG and satisfaction with convalescence was significantly lower after heart valve surgery. The clinics differed with respect to the reported somatic complaints and satisfaction scales.Conclusion: The results demonstrate the practicability and validity of the ANP-KA for the assessment of postoperative complaints and patient satisfaction after cardiac surgery. [ABSTRACT FROM AUTHOR]- Published
- 2005
24. Untersuchungen zum Einfluss von pulsatilem und nicht-pulsatilem Fluss auf zentralnervöse und renale Schädigung im Rahmen einer kardiochirurgischen Bypassoperation beim erwachsenen Patienten
- Author
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Graßler, Angelika, Liebold, Andreas, and Träger, Karl
- Subjects
Pulsatile flow ,Nierenversagen ,Fibrinolyse ,Cardiopulmonary bypass ,Fibrinolysis ,Herz-Lungen-Maschine ,Akute Niereninsuffizienz ,Kardiopulmonaler Bypass ,Acute kidney injury ,Pulsatiler Fluss ,Heart-lung machine ,ddc:610 ,DDC 610 / Medicine & health - Abstract
Renale und zentralnervöse Komplikationen gehören zu den häufigsten Nebenwirkungen der kardiopulmonalen Bypassoperation. Durch pulsatilen Fluss einer minimierten extrakorporalen Zirkulation könnte die intraoperative Organdurchblutung verbessert und damit neuronale und renale Schädigungen nach Bypassoperation reduziert werden. In der vorliegenden prospektiv randomisierten Studie wurden 40 kardiochirurgische Bypass Patienten randomisiert einer puls bzw. non-puls Gruppe zugeteilt. Bei ihnen wurden übliche klinische Parameter und neuere Biomarker der Niere, des zentralen Nervensystems und der Fibrinolyse zu definierten prä-, intra- und postoperativen Zeitpunkten aus Blut und Urin bestimmt und deren Verlauf in den beiden Studiengruppen miteinander verglichen. Dabei konnten kaum signifikante Unterschiede zwischen beiden Betriebsarten gefunden werden, ein positiver Einfluss der Pulsation konnte nicht belegt werden.
- Published
- 2020
- Full Text
- View/download PDF
25. Unterkühlung.
- Author
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Römer, M. and Sänger, S.
- Abstract
Copyright of Notfall & Rettungsmedizin is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2003
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26. Aprotinin und Heparin – Beschichtete Bypasssysteme bei reduzierter systemischer Heparinisierung.
- Author
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Kipfer, Beat, Englberger, Lars, Berdat, Pascal, Gygax, Erich, Nydegger, Urs, and Carrel, Thierry
- Abstract
Copyright of Zeitschrift für Herz-, Thorax- und Gefaesschirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2002
- Full Text
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27. Kardiopulmonaler Bypass vermindert den bronchialarteriellen Blutfluss.
- Author
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Schlensak, Christian, Doenst, Torsten, Wunderlich, Mark, Preußer, Stefan, Kleinschmidt, Manuela, and Beyersdorf, Friedhelm
- Abstract
Copyright of Zeitschrift für Herz-, Thorax- und Gefaesschirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2002
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28. “Partielle CO2-Rückatmungstechnik” versus Thermodilution Bestimmung des Herzzeitvolumens vor und nach.
- Author
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Neuhäuser, C., Müller, M., Bräu, M., Scholz, S., Böning, O., Roth, P., and Hempelmann, G.
- Abstract
Copyright of Anaesthesist is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2002
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29. Einfluss der humoralen Immunantwort auf den klinischen Verlauf nach aortokoronarer Bypass-Operation.
- Author
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Rothenburger, M., Soeparwata, R., Hoffmeier, A., Berendes, E., Tjan, T. D. T., Schmid, C., and Scheld, H. H.
- Abstract
Copyright of Zeitschrift für Herz-, Thorax- und Gefaesschirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2001
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30. Study protocol: NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC trial): a randomised controlled trial
- Author
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Yves d’Udekem, Simon Erickson, Marino Festa, Stephen Brian Horton, Debbie Amanda Long, John Beca, Nelson Alphonso, Kerry Johnson, Carmel Delzoppo, Kim van Loon, B Gannon, Jonas Fooken, Antje Blumenthal, Warwick Butt, Steve Horton, Johnny Millar, David Buckley, Taryn Evans, Claire Sherring, John Artrip, Killian O’Shaughnessy, Rebecca Fletcher, Simon Byrne, Sam Barr, Rae Kelly, Deborah Long, Kerry Johnston, Carla Zuzak, Benjamin Anderson, Nicole J C W van Belle-van Haaren, Bram van Wijk, Erik Koomen, University of Zurich, and Schibler, Andreas
- Subjects
Heart Defects, Congenital ,Male ,medicine.medical_specialty ,Cardiotonic Agents ,Heart disease ,medicine.medical_treatment ,lcsh:Medicine ,610 Medicine & health ,2700 General Medicine ,Nitric Oxide ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Superiority Trial ,Double-Blind Method ,Randomized controlled trial ,law ,Protocol ,Cardiopulmonary bypass ,Humans ,Medicine ,030212 general & internal medicine ,Cardiac Surgical Procedures ,Randomized Controlled Trials as Topic ,Mechanical ventilation ,child ,Cardiopulmonary Bypass ,business.industry ,ventilation ,lcsh:R ,Intensive Care ,Infant ,General Medicine ,medicine.disease ,congenital heart disease ,mortality ,3. Good health ,Cardiac surgery ,Clinical trial ,inflammation ,10036 Medical Clinic ,Anesthesia ,Female ,Risk Adjustment ,business ,030217 neurology & neurosurgery - Abstract
IntroductionCongenital heart disease (CHD) is a major cause of infant mortality. Many infants with CHD require corrective surgery with most operations requiring cardiopulmonary bypass (CPB). CPB triggers a systemic inflammatory response which is associated with low cardiac output syndrome (LCOS), postoperative morbidity and mortality. Delivery of nitric oxide (NO) into CPB circuits can provide myocardial protection and reduce bypass-induced inflammation, leading to less LCOS and improved recovery. We hypothesised that using NO during CPB increases ventilator-free days (VFD) (the number of days patients spend alive and free from invasive mechanical ventilation up until day 28) compared with standard care. Here, we describe the NITRIC trial protocol.Methods and analysisThe NITRIC trial is a randomised, double-blind, controlled, parallel-group, two-sided superiority trial to be conducted in six paediatric cardiac surgical centres. One thousand three-hundred and twenty infants Ethics and disseminationThe study has ethical approval (HREC/17/QRCH/43, dated 26 April 2017), is registered in the Australian New Zealand Clinical Trials Registry (ACTRN12617000821392) and commenced recruitment in July 2017. The primary manuscript will be submitted for publication in a peer-reviewed journal.Trial registration numberACTRN12617000821392
- Published
- 2019
31. Splanchnikusperfusion unter Dopexamin bei kardiochirurgischen Eingriffen.
- Author
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Bach, F., Silomon, M., Grundmann, U., Stürner, J., Graeter, T., and Larsen, R.
- Abstract
Copyright of Anaesthesist is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 1999
- Full Text
- View/download PDF
32. Procalcitonin nach extrakorporaler Zirkulation Synthese im Hepatosplanchnikusgebiet?
- Author
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Silomon, M., Bach, F., Ecker, D., Graeter, T., Grundmann, U., and Larsen, R.
- Abstract
Copyright of Anaesthesist is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 1999
- Full Text
- View/download PDF
33. Fremdblutsparende Verfahren in der Kinderherzchirurgie
- Author
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Redlin, Mathias
- Subjects
paediatric cardiac surgery ,morbidity ,cardiopulmonary bypass ,600 Technik, Medizin, angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit ,transfusion - Abstract
t Die Kernaussage dieser Arbeit betrifft den Nachweis, dass auch im Bereich der pädiatrischen Herzchirurgie eine deutliche Reduktion der Transfusionshäufigkeit von Fremdblut machbar und sinnvoll ist. Die in vielen Fällen unvermeidliche Transfusionsindikation ergibt sich vor allem aus dem eklatanten Missverhältnis zwischen dem Blutvolumen des zu operierenden Kindes und dem sicheren Mindestfüllvolumen einer herkömmlich dimensionierten Herz-Lungen-Maschine (HLM). Dabei wird das errechnete intravasale Blutvolumen durch das Füllvolumen der HLM häufig um mehr als das 2 bis 3fache überschritten. Dieses Vorgehen führt bei fremdblutfreier Vorbereitung der HLM unweigerlich zu einer kritischen Hämodilution. Eine daraus resultierende kritische Sauerstoffuntersättigung lässt sich nur durch die anteilige Zugabe von Fremderythrozyten verhindern. Wenn dagegen durch Miniaturisierung der HLM eine deutliche Reduktion des Füllvolumens erreichbar ist, werden fremdblutfreie Operation auch bei Neugeborenen mit einem komplexen Herzfehler ohne Vernachlässigung der Patientensicherheit möglich. Durch die routinemäßige Verwendung gewichtsadaptierter HLM-Sets in Kombination mit einem umfassenden fremdblutsparenden Konzept ergibt sich ein deutlich vermindertes Transfusionserfordernis für Kinder aller Altersgruppen. Der klinische Nutzen dieses Vorgehens wird in einer Analyse zur postoperativen Morbidität (Beatmungszeit und intensivstationäre Verweildauer) erhärtet. Bei Unvermeidbarkeit einer allogenen Bluttransfusion ist das Lagerungsalter der verwendeten Erythrozytenkonzentrate zu beachten und die Dauer von 6 Tagen nicht zu überschreiten. Zum anderen sollte die Fremdbluttransfusion möglichst nicht während der eigentlichen HLM-Phase erfolgen (Aggravierung unerwünschter Nebenwirkungen durch potentiell lagerungsgeschädigte Fremderythrozyten, transarterieller Transfusionsweg an der HLM). Als Fazit dieser Arbeit gilt die prinzipielle Machbarkeit einer fremdblutfreien HLM-Füllung für alle Altersklassen. Dieses Vorgehen ist seit 2014 Standard am Deutschen Herzzentrum Berlin. Dabei gilt als oberste Maxime, dass eine restriktive Transfusionsstrategie niemals zu einem Sauerstoffmangel der peripheren Organe und Gewebe führen darf. Daher ist im Grenzbereich zur kritischen Hämodilution, neben einem ausgedehnten obligatorischen Monitoring, der Einsatz der Nahinfrarotspektroskopie zur Überwachung einer jederzeit sicheren Gewebeoxygenierung absolut unverzichtbar. Angesichts der Vielzahl transfusions-assoziierter Nebenwirkungen ist eine zurückhaltende Einstellung zur Gabe von Fremdblut auch im Bereich der pädiatrischen Herzchirurgie sinnvoll. Umsetzbar ist dieses restriktive Transfusionsverhalten nur im Konsens mit allen beteiligten Fachdisziplinen. Der verantwortungsbewusste Verzicht auf allogene Transfusionen bedeutet neben ressourcenschonenden Aspekten auch eine direkte Kostenersparnis. Primär sehen wir in diesem Vorgehen neben dem direkten perioperativen Nutzen auch einen Vorteil für die sich anschließende weitere Lebensphase der herzchirurgisch zu versorgenden Kinder.
- Published
- 2019
34. Akutes Chorea-Syndrom nach Herzoperation am hypothermen kardiopulmonalen Bypass (Post pump chorea, PPC).
- Author
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Kaulitz, Renate, Bergmann, Per, Heyer, Raban, and Kallfelz, Hans Carlo
- Abstract
Copyright of Monatsschrift Kinderheilkunde is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 1997
- Full Text
- View/download PDF
35. Rekombinantes Hirudin als Antikoagulans für den kardiopulmonalen Bypass in der Herzchirurgie: Klinische Erfahrungen.
- Author
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Riess, F., Pötzsch, B., Bleese, N., Greinacher, A., Hollnick, G., Löwer, C., Madlener, K., Siebert, K., Völpel, H., and Müller-Berghaus, G.
- Abstract
Copyright of Zeitschrift für Herz-, Thorax- und Gefaesschirurgie is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 1997
- Full Text
- View/download PDF
36. Neuromonitoring und Neuroprotektion in der Kardioanästhesie: Bundesweite Umfrage des Arbeitskreises Kardioanästhesie der Deutschen Gesellschaft für Anästhesiologie und Intensivmedizin e.V
- Author
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I. Tzanova, U. Schirmer, Jörg Ender, and G. Erdös
- Subjects
medicine.medical_specialty ,Mean arterial pressure ,Cardiac output ,business.industry ,General Medicine ,law.invention ,Anesthesiology and Pain Medicine ,Intravenous anesthesia ,Bypass surgery ,law ,Anesthesiology ,Anesthesia ,medicine ,Cardiopulmonary bypass ,Elective surgery ,business ,Propofol ,medicine.drug - Abstract
OBJECTIVE: The primary objective of this nationwide survey carried out in department of cardiac anesthesia in Germany was to identify current practice with regard to neuromonitoring und neuroprotection. METHODOLOGY: The data are based on a questionnaire sent out to all departments of cardiac anesthesia in Germany between October 2007 und January 2008. The anonymized questionnaire contained 26 questions about the practice of preoperative evaluation of cerebral vessels, intra-operative use of neuromonitoring, the nature und application of cerebral protective measures, perfusion management during cardiopulmonary bypass, postoperative evaluation of neurological status, and training in the field of cerebral monitoring. RESULTS: Of the 80 mailed questionnaires 55% were returned and 90% of department evaluated cerebral vessels preoperatively with duplex ultrasound. The methods used for intra-operative neuromonitoring are electroencephalography (EEG, 60%) for type A dissections (38.1%), for elective surgery on the thoracic and thoraco-abdominal aorta (34.1% and 31.6%, respectively) and in carotid surgery (43.2%) near infrared spectroscopy (40%), evoked potentials (30%) and transcranial Doppler sonography (17.5%), with some centers using combined methods. In most departments the central nervous system is not subjected to monitoring during bypass surgery, heart valve surgery, or minimally invasive surgery. Cerebral protective measures used comprise patient cooling on cardio-pulmonary bypass (CPB 100%), extracorporeal cooling of the head (65%) and the administration of corticosteroids (58%), barbiturates (50%) and antiepileptic drugs (10%). Neuroprotective anesthesia consists of administering inhalation anesthetics (32.5%; sevoflurane 76.5%) and intravenous anesthesia (20%; propofol and barbiturates each accounting for 46.2%). Of the departments 72.5% cool patients as a standard procedure for surgery involving cardiovascular arrest and 37.5% during all surgery using CPB. In 84.6% of department CPB flow equals calculated cardiac output (CO) under normothermia, while the desired mean arterial pressure (MAP) varies between 60 and 70 mmHg (43.9%) and between 50 and 60 mmHg (41.5%), respectively. At body temperatures less than 18 degrees C CPB flow is reduced below the calculated CO (70%) while 27% of departments use normothermic flow rates. The preferred MAP under hypothermia is between 50 and 60 mmHg (59%). The results of intra-operative neuromonitoring are documented on the anesthesia record (77%). In 42.5% of the departments postoperative neurological function is estimated by the anesthesiologist. Continuing education sessions pertaining to neuromonitoring are organized on a regular basis in 32.5% of the departments and in 37.5% individual physicians are responsible for their own neuromonitoring education. CONCLUSION: The present survey data indicate that neuromonitoring and neuroprotective therapy during CPB is not standardized in cardiac anesthesiology departments in Germany. The systemic use of available methods to implement multimodal neuromonitoring would be desirable.
- Published
- 2018
37. Extrakorporale Zirkulation: Derzeitiger Stand und aktuelle Entwicklungen
- Author
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Liebold, A.
- Published
- 2015
- Full Text
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38. Peripartale Aortendissektion.
- Author
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Pachler, C., Knez, I., Petru, E., Dörfler, O., Vicenzi, M., and Toller, W.
- Subjects
- *
AORTIC dissection , *CHEST pain , *CESAREAN section , *ECHOCARDIOGRAPHY , *CARDIOPULMONARY bypass , *GYNECOLOGY , *CARDIAC arrest - Abstract
A 29-year-old primagravida developed severe chest pains during labor. An emergency caesarean section was performed as the symptoms persisted. Imaging diagnosis immediately after delivery revealed an acute proximal (type A) aortic dissection. The patient was transferred to the nearest cardiothoracic surgery centre and successful emergency surgical aortic repair was performed. The perioperative course of a type A aortic dissection during pregnancy and labor is complicated by time pressure, diagnostic restrictions until delivery and potentially fatal uterine bleeding during cardiopulmonary bypass and hypothermic cardiac arrest. This case report describes the diagnosis and the surgical, anesthesiological and gynecological management of this life-threatening peripartum complication. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
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39. The use of levosimendan in cardiac surgery: an update after the LEVO-CTS, CHEETAH and LICORN trials in the light of clinical practice
- Author
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Stefaan Bouchez, Matti Kivikko, Fabio Guarracino, Piero Pollesello, Angela Rajek, Matthias Heringlake, Vladimir V. Lomivorotov, Bernard Cholley, Dominique Bettex, University of Zurich, and Pollesello, Piero
- Subjects
Inotrope ,030204 cardiovascular system & hematology ,law.invention ,PULMONARY-HYPERTENSION ,RETROSPECTIVE ANALYSIS ,0302 clinical medicine ,systematic review ,Risk Factors ,030202 anesthesiology ,law ,Medicine and Health Sciences ,Randomized Controlled Trials as Topic ,VALVE SURGERY ,Evidence-Based Medicine ,Ejection fraction ,CARDIOPULMONARY BYPASS ,INTRAAORTIC BALLOON PUMP ,OUTPUT SYNDROME ,Cardiac surgery ,Treatment Outcome ,3004 Pharmacology ,HEART-FAILURE ,Cardiology and Cardiovascular Medicine ,cardiac surgery ,medicine.drug ,medicine.medical_specialty ,Consensus ,Heart Diseases ,10216 Institute of Anesthesiology ,Clinical Decision-Making ,610 Medicine & health ,Perioperative Care ,2705 Cardiology and Cardiovascular Medicine ,levosimendan ,03 medical and health sciences ,LEFT-VENTRICULAR FUNCTION ,LOW EJECTION FRACTION ,medicine ,Cardiopulmonary bypass ,Humans ,Cardiac Surgical Procedures ,HIGH-RISK PATIENTS ,Intensive care medicine ,Simendan ,Pharmacology ,clinical trials ,business.industry ,Patient Selection ,Cardiovascular Agents ,Levosimendan ,Perioperative ,Congresses as Topic ,medicine.disease ,Drugs in the Pipeline ,Clinical trial ,opinion paper ,Heart failure ,business - Abstract
Levosimendan is a calcium sensitizer and ATP-dependent potassium channel opener which exerts sustained hemodynamic, symptomatic and organ-protective effects. It is registered for the treatment of acute heart failure, and when inotropic support is considered appropriate. In the past fifteen years, levosimendan has been widely used in clinical practice, and has also been tested in clinical trials to stabilize at-risk patients undergoing cardiac surgery. Recently, three randomized, placebo-controlled, multicenter studies (LICORN, CHEETAH and LEVO-CTS) have been published reporting on the peri-operative use of levosimendan in patients with compromised cardiac ventricular function. Taken together, many smaller trials conducted in the past suggested beneficial outcomes with levosimendan in peri-operative settings. In contrast, the latest three studies were neutral or inconclusive. In order to understand the reasons for such dissimilarity, a group of experts from Austria, Belgium, Finland, France, Germany, Italy, Switzerland, and Russia, including investigators from the three most recent studies, met to discuss the study results in the light of both the previous literature and current clinical practice. Despite the fact that the null hypothesis could not be ruled out in the recent multicenter trials, we conclude that levosimendan can still be viewed as a safe and effective inodilator in cardiac surgery.This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Published
- 2018
40. Untersuchungen zum postoperativen Einsatz eines Zytokinadsorbers (CytoSorb) bei herzchirurgischen Patienten mit überschießender inflammatorischer Reaktion nach kardiopulmonalem Bypass
- Author
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Fritzler, Daniel, Träger, Karl, and Skrabal, Christian
- Subjects
CytoSorb ,Cardiopulmonary bypass ,Hemodynamics ,Laktat ,Kardiopulmonaler Bypass ,postCPB SIRS ,Fallserie ,Zytokine ,Zytokinadsorption ,SIRS ,Cytokines ,Lactate ,ddc:610 ,Hämodynamik ,DDC 610 / Medicine & health ,Cytokine ,Cardiac surgical procedures ,Herzchirurgie ,Allgemeine Entzündungsreaktion - Abstract
Die überschießende inflammatorische Reaktion nach kardiopulmonalem Bypass, kurz postCPB SIRS (Systemisches Inflammatorisches Response Syndrom nach kardiopulmonalem Bypass), ist das Resultat einer Reihe von Faktoren, welche durch die chirurgische Intervention während kardiopulmonalem Bypasses hervorgerufen werden können. Diese unter anderem durch den kardiopulmonalen Bypass selbst getriggerte Antwort, die episodisch zu einer übermäßigen Entzündungsreaktion führen kann, mit massiv erhöhten Spiegeln an proinflammatorischen Zytokinen einhergeht und in einem manifesten Systemisches Inflammatorisches Response Syndrom (SIRS) resultiert, kann im äußersten Fall in multiplen Organdysfunktionen enden. Für die intensivmedizinische Behandlungsstrategie werden Maßnahmen benötigt, die diese Entwicklung zu beherrschen helfen. Als eine solche effektive Maßnahme,könnte sich hierin der Einsatz eines neuartigen Zytokinadsorbers, CytoSorb™ erweisen. Die vorliegende Fallserie umfasst ein Patientenkollektiv von 35 Patienten, die begleitende Auswertung sowie deskriptive Darstellung der protokollierten Daten. Es handelt sich dabei um Patienten, die intensivmedizinisch behandelt wurden und bei denen eine Therapie mit CytoSorb™ zum Einsatz kam. 25 Patienten (71%) überlebten das postCPB SIRS, während weitere 10 Patienten (29%) verstarben. Zentrale Komponente der Methodik war die prospektive Erhebung und Auswertung relevanter Messdaten zur Dynamik von Inflammationsparametern, der metabolischen Parameter Laktat und BE sowie hämodynamischer Indikatoren. Zudem wurde eine Risikostratifizierung initialer und finaler Behandlungsdaten,mittels verschiedener Scoringsysteme durchgeführt, um einen Einfluss der Therapieoption CytoSorb™ auf die Mortalitätswahrscheinlichkeit zu bestimmen. Es wurde weiter eine mikrobiologische Diagnostik durchgeführt, um eine potenzielle Besiedlung des Adsorbersystems mit Mikroorganismen und damit die Gefahr einer mikrobiellen Besiedlung eines Systems mit sehr hoher Oberfläche auszuschließen. Zudem wurden stichprobenartig Filtersysteme einer elektronenmikroskopischen Analyse zur Detektion eventuell kontraproduktiver Veränderungen zugeführt. Als wesentliches und primäres Ergebnis resultierte aus der Analyse erwogener Daten eine Assoziation zwischen der Therapie mit CytoSorb™ und einer Abnahme der Zytokinkonzentrationen. Darüber hinaus nahm die therapeutische Intervention Einfluss auf eine Stabilisierung der hämodynamischen und metabolischen Parameter. Auch Organdysfunktionen, welche im Rahmen des SIRS auftraten,konnten im Laufe der Behandlung weitestgehend kontrolliert werden. Insgesamt konnte dem Adsorbersystem neben seiner simplen Anwendungsweise eine gute Verträglichkeit attestiert werden, da sich keine Hinweise auf eine assoziierte schwerwiegende Nebenwirkung unter der Behandlung ergaben. Im aktuellen Kontext der Forschung und therapeutischen Optionen des SIRS (Systemisch Inflammatorischen Response Syndrom), respektive seiner unmittelbar durch Intervention eines kardiopulmonalen Bypass und auf diesen nachfolgend induzierten Variante und welches sich initial vornehmlich durch eine hämodynamische Instabilität der Patienten mit zusätzlich hoher Katecholaminzufuhr präsentiert, könnte die Zytokinadsorption via CytoSorb™ einen vorteilhaften Beitrag leisten. Die positive klinische Bewertung dieser Fallserie gibt einen affirmativen Ausblick für die therapeutische Intervention und entsprechende Effizienz einer Hämadsorption mit einem Zytokinadsorber in diesem Bereich. Es ist anzumerken, dass zur Vertiefung des gegenwärtigen Kenntnisstandes weitere Forschungsarbeiten nötig sind, um den empirischen Benefit dieser Behandlungsform evidenzbasiert zu verifizieren. Hierzu können randomisierte und kontrollierte Untersuchungen eine mögliche Bestätigung leisten.
- Published
- 2018
- Full Text
- View/download PDF
41. 'Vergleichende Untersuchungen zu Änderungen der Nierenfunktion anhand drei verschiedener Strategien der operativen Myokardrevaskularisation'
- Author
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Deininger, Stefanie, Liebold, Andreas, and Orend, Karl-Heinz
- Subjects
Alpha-GST ,Cardio-renal syndrome ,Coronary artery bypass, off-pump ,Extracorporal circulation ,Cardiopulmonary bypass ,Perkutane transluminale Angioplastie ,Nierenfunktion ,Herz-Lungen-Maschine ,Tubuläre Biomarker ,Kardiopulmonaler Bypass ,Koronare Revaskularisation ,L-FABP ,Myocardial revascularization ,Lipocalin-2 ,Extrakorporale Zirkularisation ,Off-Pump ,Heart-lung machine ,ddc:610 ,NGAL ,KIM-1 ,DDC 610 / Medicine & health - Abstract
Hintergrund: Die Anwendung der extrakorporalen Zirkulation zur Unterstützung der Myokardrevaskularisation ist mit einem erhöhten Risiko für das Auftreten von Nierenschäden verbunden. In wie weit sich tubuläre Schäden auf die Nierenfunktion auswirken ist nicht bekannt. Die folgende Studie untersuchte perioperative Nierenschäden und -funktion anhand der konventionellen extrakorporalen Zirkularisation (HLM), der minimierten extrakorporalen Zirkularisation (MECC) und dem Off-pump Verfahren (OPCAB). Methoden: Blut- und Urinproben wurden präoperativ und bis zu 72 Stunden postoperativ zu sieben Zeitpunkten von 120 Patienten der HEPCON Studie (DRKS00007580) gesammelt. NGAL, KIM-1, L-FABP, alpha-GST als Parameter tubulärer Schäden wurden aus Urinproben mittels ELISA bestimmt. Um die Nierenfunktion im Verlauf zu bestimmen wurden Kreatinin und Harnstoff im Serum, sowie die errechnete GFR bestimmt. Ergebnisse: Tubuläre Marker unterschieden sich in der frühen postoperativen Phase signifikant zwischen den Operationstechniken. Die meisten Schäden konnten beim HLM-Verfahren detektiert werden. Hämolyse und Hämodilution korrelierten mit diesen postoperativen Nierenschäden. Zeitverläufe der Funktionsparameter zeigten keine Unterschiede zwischen den Operationstechniken, auch das Auftreten von akuten Nierenschäden bei 15 Patienten (13,5%) war nicht abhängig vom Operationsverfahren. Fazit: Das Verfahren der konventionellen extrakorporalen Zirkularisation verursacht temporär mehr tubuläre Schäden, als das MECC- oder OPCAB-Verfahren. Spätere Einbussen der Nierenfunktion waren nicht vom Operationsverfahren abhängig.
- Published
- 2017
42. Ruptur der A. thoracica interna 6 Wochen nach MIDCAB-Operation.
- Author
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Dehne, M. G., Meckum, J., Dumitriu, M., and Matheis, G.
- Subjects
- *
CORONARY artery bypass , *CARDIAC surgery , *SURGERY , *MEDICINE , *THERAPEUTICS - Abstract
The minimally invasive coronary bypass operation is a procedure that has been firmly established in cardiac surgery for several years now. Only a few reports exist regarding the complications of this procedure. This case study reports on a 51-year-old man who collapsed 27 days after a left-sided internal mammary artery bypass on the anterior interventricular artery, when the bypass vessel ruptured. After pericardial puncture and cardiopulmonary resuscitation the patient was transported via air ambulance to a cardio-surgical center where he was successfully operated upon. [ABSTRACT FROM AUTHOR]
- Published
- 2008
- Full Text
- View/download PDF
43. [Infiltration of Cardiac Vessels by Lung Cancer: Incidence, Classification, Operative Technique with Heart Lung Bypass, and Results]
- Author
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A, Kirschbaum and N, Mirow
- Subjects
Heart Neoplasms ,Cardiopulmonary Bypass ,Lung Neoplasms ,Incidence ,Aortic Diseases ,Humans ,Neoplasm Invasiveness ,Heart Atria ,Pulmonary Artery ,Neoplastic Cells, Circulating ,Coronary Vessels ,Vascular Neoplasms ,Neoplasm Staging - Abstract
Carcinomas of the lung that infiltrate the blood vessels close to the heart (left atrium, pulmonary artery and aorta) without spreading to mediastinal lymph nodes or developing distant metastases are rare overall. Such situations are often classified as primarily inoperable by interdisciplinary tumour boards. This is only the case if, for technical reasons, an experienced thoracic surgeon does not feel able to perform a resection with a surrounding margin of healthy tissue. The surgical strategy to be employed must be chosen individually depending on the infiltrated structure. Complete tumour staging should always be carried out. This also helps in deciding whether neoadjuvant chemotherapy should be given before resection. A heart-lung machine must always be used if larger defects occur due to the resection of blood vessels close to the heart. Using a heart-lung machine in the case of tumour resection does not lead to problems of tumour cell dissemination. Nevertheless, the duration of use of the heart-lung machine should be kept to a minimum, also because of the anticoagulation required. The cardiac defects can be closed securely with the bovine patching materials that are now available. Postoperative morbidity and mortality are low after such resections. Curative resection of blood vessels close to the heart infiltrated by carcinomas of the lung can lead to 5-year survival rates of up to 50 %.
- Published
- 2016
44. Was der Herzchirurg schon immer über die Herz-Lungen-Maschine wissen wollte
- Author
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Benk, Christoph, Klemm, R., Schaller, S., Brehm, K., Schlensak, C., and Beyersdorf, F.
- Published
- 2008
- Full Text
- View/download PDF
45. Ist das SIRS/Sepsis-Syndrom in der Herzchirurgie Folge der extrakorporalen Zirkulation und damit unvermeidlich?
- Author
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Boeken, Udo and Feindt, P.
- Published
- 2008
- Full Text
- View/download PDF
46. Heparin-induzierte Thrombozytopenie (HIT) bei Operationen unter Verwendung der Herz-Lungen-Maschine und bei Patienten mit mechanischer Kreislaufunterstützung
- Author
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Selleng, S. and Greinacher, A.
- Published
- 2007
- Full Text
- View/download PDF
47. Fremdblutfreier kardiopulmonaler Bypass bei vier Angehörigen der Religionsgemeinschaft „Jehovas Zeugen“ mit einem Körpergewicht unter 5 kg
- Author
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Böttcher, W., Schulz, F., Gutsch, E., Hübler, M., Koster, A., Redlin, M., Alexi-Meskishvili, V., Kuppe, H., Berger, F., and Hetzer, R.
- Published
- 2006
- Full Text
- View/download PDF
48. Erste Erfahrungen in der prophylaktischen Anwendung von Surfactant bei Patienten mit Lungenerkrankungen in der Herzchirurgie
- Author
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Schmale, M., Schubert, S., Kroll, H., Kösters, V., Scheubel, R., Baulig, W., Sablotzki, A., and Grond, S.
- Published
- 2006
- Full Text
- View/download PDF
49. Koronare Notfalleingriffe im Akuten Koronarsyndrom: Beating-heart versus konventionelle Bypasschirurgie: Eine Propensity Analyse der kurz- und langfristigen Ergebnisse
- Author
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Rastan, A. J., Kempfert, J., Eckenstein, J. I., Hentschel, B., Funkat, A. K., Walther, T., Lehmann, S., and Mohr, F. W.
- Published
- 2006
- Full Text
- View/download PDF
50. Endothelaktivierung und Gewebehypoperfusion: —Ursachen eines SIRS in der offenen Herzchirurgie?
- Author
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Litmathe, J., Boeken, U., Feindt, P., and Gams, E.
- Published
- 2005
- Full Text
- View/download PDF
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