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2 results on '"Castiglione F"'

1. [Controversies around the prevention of stress bleeding].

Author

Castiglione F, Jehle EC, and Blum AL

Subjects
Cross Infection epidemiology, Cross Infection etiology, Humans, Peptic Ulcer Hemorrhage epidemiology, Peptic Ulcer Hemorrhage etiology, Peptic Ulcer Hemorrhage mortality, Pneumonia epidemiology, Pneumonia etiology, Stress, Psychological complications, Peptic Ulcer Hemorrhage prevention & control, Stress, Psychological prevention & control
Published
1990
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2. [Prevention of stress ulcer hemorrhage: a risk-benefit analysis].

Author

Jehle EC, Castiglione F, and Blum AL

Subjects
Anti-Ulcer Agents administration & dosage, Cause of Death, Cross Infection mortality, Humans, Peptic Ulcer Hemorrhage mortality, Pneumonia mortality, Prospective Studies, Retrospective Studies, Survival Rate, Critical Care, Peptic Ulcer Hemorrhage prevention & control, Stress, Physiological complications
Abstract

The potential benefits and risks of prophylactic treatment for stress ulcer haemorrhage remain controversial. Analysis of previous studies indicates that 1. the incidence of haemorrhage and the mortality from haemorrhage have declined over the last two decades even in the absence of prophylactic treatment; 2. all drugs used for prophylaxis reduce the incidence of haemorrhage, and all drugs are comparably effective. 3. There is, however, no evidence that prophylactic drug therapy reduces the mortality or that the drugs used for prophylaxis differ in their effect on mortality. 4. A higher rate of pneumonia is seen only with antacid treatment.

Published
1990

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