1. Antibiotikaresistenzen von E. coli in Urinproben: Prävalenzdaten dreier Laboratorien im Raum Zürich von 1985 bis 2010.
- Author
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Savaria, F., Zbinden, R., Wüst, J., Burnens, A., Ledergerber, B., Weber, R., and Kovari, H.
- Subjects
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ANTI-infective agents , *DRUG resistance in microorganisms , *URINARY tract infection treatment , *ESCHERICHIA coli , *DISEASE prevalence - Abstract
Urinary tract infections in women are common. Drug resistance among Escherichia coli, the most frequent uropathogen, has increased worldwide. In a prevalence study we investigated the local antibiotic susceptibility of this microorganism in urinary specimens of three laboratories in Zurich. Resistance rates against trimethoprim-sulfamethoxazole 2010 were 28%, 16% against quinolones and 16% against amoxicillin/clavulanic acid. Resistance prevalence for nitrofurantoin and fosfomycin were low with 3,6%, resp. 0,7%. The rate of extended-spectrum β-lactamase-producing E. coli has rapidly increased to 4,3% in 2010. Based on this data and according to the international guidelines for the treatment of uncomplicated cystitis, therapy with trimethoprim-sulfametho xazole and quinolones are no longer recommended. Nitrofurantoin and Fosfomycin are an appropriate choice. Microbiological testing is advised. [ABSTRACT FROM AUTHOR]
- Published
- 2012
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