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The aim of the "Youth Forum of the DGOU" during the Convention 2010 in Heidelberg was to place a statement concerning the professional politics in the field of Orthopaedic and Trauma Surgery. The Bologna Process realizes a standardization of the academic training within the European Union. For medicine this concept would raise the opportunity to opt out after three years with a bachelor degree applying for alternative occupations within the health care system. However, these alternative occupations are rarely defined and, in addition, the current structure of medical school in Germany provides the highest possible education for doctors in a direct and very well established way. Thus, reforming medical school in Germany into a Bachelor-master's system is an ambivalent approach, which considers a thorough reappraisal. There is currently no necessity for an speciality training in emergency medicine. The rapid and qualified treatment by the specific subspecialty provides a high standard of care for the patient. The high frequency exposure of the trauma and orthopaedic resident with emergency cases is an essential part of the current professional training.The "Junge Forum der DGOU" continues to understand the speciality training "Facharzt für Orthopädie und Unfallchirurgie" as the basic module of the profession. After that it should be possible to continuing subspecialty training and obtaining "spezielle Unfallchirurgie" bzw "spezielle orthopädische Chirurgie". After that further subspecialty training should be encouraged.

The ultimate goal of a permanent human presence on the Moon is discussed intensively within the global lunar community. Obviously, such an effort poses stringent demands not only on the technology but also on logistics, especially considering the important aspects of masses and volume for materials and replenishments of consumables. On-site propellant production (i.e. liquid oxygen) is one of the main needs and would lead to more efficient return-to-Earth or further exploration missions. Additionally, the supply of breathable air and water for the survival of the crew on the lunar surface is also a major aspect. Thus, large effort is put into the development and research of technologies for in-situ resources utilization (ISRU) to drastically reduce the required supply from Earth and to increase the level of autonomy of a lunar outpost. The major resource on the Moon for such a purpose is regolith, which covers the first meters of the lunar surface and contains about 45% of mineralogically bounded Oxygen in terms of mass. By using adequate processing methods of this material, one could be able to extract valuable minerals and volatiles for further utilization. At DLR Bremen a compact and flexible lab experimenting facility has been developed, built and tested, which shall demonstrate the feasibility of the process by extracting oxygen out of lunar regolith, respectively soil simulants and certain minerals in the laboratory case. For this purpose, important boundary conditions have been investigated such as temperatures during the process, chemical reaction characteristics and material properties for the buildup of the facility, which shall be analyzed within this paper. Since it is one of the most elaborated chemical processes regarding ISRU and has comparably low temperature and energy constraints it has been primarily concentrated on the Hydrogen-reduction process which reduces the iron oxide component of Ilmenite (FeTiO3) within the lunar regolith. Based on the obtained results, a first line-out of a planned superior test set-up and infrastructure with pre- and post-processing units such as feeding and extraction is also presented, as well as an analysis of reaction products with common methods. This paper will present the first results of DLR efforts regarding these topics. Finally, important aspects of the future development of the processes and technologies are discussed with special consideration of lunar applicability and with respect to environmental conditions as well as mass and energy constraints.

Monoclonal antibodies against the human homologue of mouse macrosialin, CD68, are generally commercialized as markers for human monocytes and macrophages. Indeed, CD68 is considered as a selective marker for human myeloid cells, although several previous immunohistochemical studies indicate that some antibody clones also react with other hematopoietic and non-hematopoietic cell types. The aim of our study was to verify these observations and to evaluate the reliability of CD68 as a macrophage marker.We investigated protein and RNA expression of CD68 in various fibroblast types and carcinoma cell lines as compared to monocytes and macrophages using immunohistochemistry, flow cytometry, and specific RT-PCR. Different monoclonal antibody clones against CD68 were applied including KP-1 and EBM11.As expected, the intensity of immunohistochemical and flow cytometric CD68 staining was dependent on both the antibody clone and the fixation procedure. However, fibroblasts isolated from normal skin, normal breast, breast tumor tissue, and osteoarthritis synovia clearly expressed CD68 protein at levels comparable to macrophages. The specificity of CD68 expression in fibroblasts was verified by RT-PCR which also showed some tumor cell types to express CD68 mRNA.Our findings clearly demonstrate that the expression of CD68 is not restricted to the macrophage lineage. This is highly relevant for experimental and diagnostic purposes, since anti CD68 antibodies cannot be accepted without reservations for the discrimination of myeloid cells and fibroblasts even in paraffin sections after formalin fixation.