15 results on '"Ratjen F"'
Search Results
2. Pulmonale Manifestation einer Sarkoidose im Kleinkindesalter
- Author
-
Büscher, R., Schaper, J., Müller, K.-M., and Ratjen, F.
- Published
- 1997
- Full Text
- View/download PDF
3. Einseitige Lungentransplantation bei einem 11 jährigen Patienten mit zystischer Fibrose
- Author
-
Büscher, R., Geiger, A., Markgraf, G., Reidemeister, C., and Ratjen, F.
- Published
- 1997
- Full Text
- View/download PDF
4. N14 - Pneumonie/Bronchopneumonie (bakteriell und viral)
- Author
-
RATJEN, F., GÖTZ, M., and PAUL, K.
- Published
- 2015
- Full Text
- View/download PDF
5. Autorenverzeichnis
- Author
-
Graul-Neumann, L., Horn, D., Hübner, C., Huppke, P., König, R., Majewski, F., Meinecke, P., Pankau, R., Rosenbaum, T., Schnabel, D., Schuelke, M., Spranger, J., Theile, U., Tinschert, S., Wilichowski, E., Wollmann, H.A., Zenker, M., Bartmann, P., Bassler, D., Bührer, C., Flemmer, A.W., Forster, J., Franz, A., Gonser, M., Gortner, L., Groneck, P., Hentschel, R., Herting, E., Hoyme, U.B., Hummler, H., Jandeck, C., Jorch, G., Korinthenberg, R., Liese, J., Maier, R.F., Martius, J., Merkenschlager, A., Poets, C.F., Pohlandt, F., Roll, C., Roos, R., Roth, B., Schneider, K.T.M., Speer, Ch., Stopfkuchen, H., Teichmann, A., Thomas, W., Vetter, K., von der Wense, A., Zielen, S., Assmann, B., Hoffmann, G.F., Kölker, S., Lindner, M., Mönch, E., Santer, R., Spiekerkötter, U., Zschocke, J., Bauer, K., Böhles, H.-J., Sinclair, Jack, Jauch, K.W., Jochum, F., Kauth, Thomas, Koletzko, B., Krawinkel, M., Krohn, K., Mihatsch, Walter, Moß, A., Mühlebach, S., Verwied-Jorky, S., Wabitsch, M., Zimmer, K.-P., Albers, N., L'Allemand, D., Binder, G., Brämswig, J.H., Dörr, H.G., Grüters-Kieslich, A., Hauffa, B.P., Heger, S., Hiort, O., Holl, R., Holterhus, P.M., Köhler, B., Korsch, Eckhard, Kratzsch, J., Krude, H., Mohnike, K., Neu, A., Pfäffle, R., Richter-Unruh, A., Riepe, F.G., Simic-Schleicher, G., Schönau, E., Sinnecker, G., Sippell, W., Willgerodt, H., Wölfle, J., Wudy, S.A., Aygören-Pürsün, E., Bas, M., Baumann, U., Biedermann, T., Blume, J., Buchholz, B., Dückers, G., Dunsch, D., Edelhäuser, M., Ehl, S., Feiterna-Sperling, C., Funk, M., Hartmann, K., Königs, C., Kreuz, W., Krudewig, J., Laws, H.-J., Linde, R., Martinez-Saguer, I., Maurer, M., Nadal, David, Niehues, T., Notheis, G., Ott, H., Schulze, I., Wedi, B., Wintergerst, U., Bürk, G., Foeldvari, I., Frosch, M., Girschick, H., Gerhold, K., Guellac, N., Haas, J.P., Häfner, R., Häuser, W., Heiligenhaus, A., Hospach, T., Horneff, G., Huppertz, H.-I., Illhardt, A., Jansson, A.F., Kallinich, T., Michels, H., Mönkemöller, K., Neudorf, U., Richter, M., Schnöbel-Müller, E., Thon, A., Zernikow, B., Behnisch, W., Cario, H., Dickerhoff, R., Eber, S., Führer, M., Kohne, E., Kulozik, A.E., Kunz, J., Muckenthaler, M., Eberl, W., Gaedicke, G., Muntean, W., Streif, W., Beck, J.D., Berthold, F., Bielack, S., Calaminus, G., Claviez, A., Creutzig, U., Dirksen, U., Dworzak, M., Göbel, U., Graf, N., Grießmeier, B., Henze, G., Hero, B., Jürgens, H., Kaiser, U., Klingebiel, T., Koscielniak, E., Kramm, C., Langer, T., Lawrenz, B., Lehrnbecher, T., Leiss, U., Mentzel, H.-J., Minkov, M., Peitz, J., Placzek, R., Reinhardt, D., Reiter, A., Rutkowski, S., Schmittenbecher, P., Schneider, D.T., Schreiber-Gollwitzer, B.M., Schrappe, M., Schroten, H., Schröder, H.M., Schuster, V., von Schweinitz, D., Sörensen, N., Tallen, G., Timmermann, B., Warmuth-Metz, M., Weckesser, M., Wessel, L., Wirth, T., Wolff, J.E.A., Wößmann, W., Zehnhoff-Dinnesen, A. am, Apitz, C., Arnold, R., Baumgartner, H., Bennink, G., Bertram, H., Blankenburg, M., Bönner, G., von der Breek, J., Breuer, J., Buchhorn, R., Bürsch, J., Cesnjevar, R., Dähnert, I., Deisenhofer, I., Diller, G.-P., Doenst, T., Dubowy, K.-O., Eicken, A., Ewert, P., Fink, C., Franke, J., Gebauer, R., Gorenflo, M., Grabitz, Haas, N.A., Häusler, H.-J., Hager, A., Hebebrand, J., Henschel, W., Hirt, M., Hoeper, M.M., Hörer, J., Hofbeck, M., Horke, A., Hraska, V., Hulpke-Wette, M., šek, J. Janou, Jux, C., Kändler, L., Kandolf, R., Kaulitz, R., Kienast, W., Klaassen, S., Knirsch, W., Kramer, H.H., Kreuder, J.G., Kriebel, T., Läer, S., Laser, K.T., Lê, T.-P., Lewin, M.A.G., Lindinger, A., Mackenzie, C.R., Mebus, S., van der Mei, S.H., Miera, O., Ovroutski, S., Paul, T., Photiadis, J., Pozza, R. Dalla, Rickers, C., Rosendahl, W., Ruschewski, W., Sachweh, J.S., Schäfers, H.-J., Scheewe, J., Schirmer, K.-R., Schlensak, C., Schlez, M., Schmaltz, A.A., Schmitt, K., Schneider, H., Schneider, M.B., Schranz, D., Schreiber, C., Schulze-Neick, I., Sieverding, L.F.J., Singer, H., Stieh, J., Sreeram, N., Thies, W.-R., Thul, J., Trauzeddel, R., Tschöpe, C., Uebing, A., Ulmer, H.E., Vogel, M., Vogt, M., Weil, J., Wessel, A., Will, J.C., Wühl, E., Ballmann, M., Barben, J., Bauer, C.P., Bend, J., Berdel, D., Blankenstein, O., Bremer, W., Brunsmann, F., Buchholz, T., Bufe, A., Derichs, N., Eber, E., Friedrichs, F., Frischer, T., Gembruch, U., Gieler, U., Götz, M., Haas, W.H., Hamelmann, E., Hammer, J., Hellermann, M., Jacobeit, J., Jung, A., Keim, V., Kitz, R., Kleinheinz, A., Koletzko, S., Kopp, I., Kopp, M., Lau, S., Lauener, R., Loff, Magdorf, K., Muche-Borowski, C., Müller, F.-M., Müsken, H., Naehrlich, L., Nicolai, T., Nüßlein, Th., Paditz, E., Palm, Frau B., Paul, K., Pfeiffer-Auler, S., Pfeiffer-Kascha, Frau D., Posselt, H.-G., Przybilla, B., Räwer, H.-C., Ratjen, F., Reese, I., Riedler, J., Rietschel, E., Rose, M., Rossi, R., Ruëff, F., Schäfer, T., Schmidt, S., Schmitt-Grohé, S., Schulze, J., Schuster, A., Seidenberg, J., Sitter, H., Smaczny, C., Spindler, T., Staab, D., Stern, M., Strassburg, C.P., Strömer, K., Stuhrmann-Spangenberg, M., Szczepanski, R., Tacke, A., Tiedgen, M., Urschitz, M.S., Vagts, J., Vogelberg, C., Wahn, U., Walker, A., Werfel, T., Wildhaber, J.H., Zach, M., Zimmermann, Th., Ballauff, A., Bannert, N., Böhn, I., Buderus, S., Bufler, P., Burdelski, M., Gerner, P., Grosse, K.-P., Henker, J., Henneke, P., Huber, W., Lang, T., Lentze, M.J., Melter, M., Müller, T., Pfister, E.-D., Rodeck, B., Schmidt-Choudhury, A., Skopnik, H., Wirth, S., Witt, H., Bachmann, H., Dötsch, J., Ehrich, J.H., Fuchshuber, Arno, Hoppe, B., Hoyer, P.F., Kemper, M.J., Michalk, D., Müller, D., Müller-Wiefel, D.E., Pohl, M., Tönshoff, B., Zerres, K., Bast, T., Baumeister, F.A.M., Berner, R., Bode, H., Christen, H.J., Collmann, H., Ebinger, F., Eiffert, H., Evers, S., Gold, R., Groß, S., Hanefeld, F., Heinen, F., Holthausen, H., Hübner, A., Jacobi, G., Karch, D., Kauschke, C., Kerkhoff, G., Kiese-Himmel, C., Klepper, J., Kohlschütter, A., Korn-Merker, E., Krägeloh-Mann, I., Kropp, P., Kurlemann, G., de Langen-Müller, U., Lenard, H.G., Michael, Th., von Moers, A., Felderhoff-Müser, U., Nau, R., Neubauer, B.A., Neuhäuser, G., Neumann, K., Noterdaeme, M., Pothmann, R., Rating, D., Reitter, B., Rickels, E., Ritz, A.M., Rosenkötter, H., Schmitt, B., Stephani, U., Stöver, B., Tibussek, D., Trollmann, R., Trommer, G., Tuxhorn, I., Wohlrab, G., Boergen, K.P., Brosch, S., Delb, W., Frank, R., Herrmann, B., von Hofacker, N., de Camargo, O. Kraus, Kries, R.v., Michaelis, R., Papousek, M., Schlack, H.G., Schriever, J., Skrodzki, K., Straßburg, H.-M., Thyen, U., Becker, K., Fels, T., Fitze, G., Grasshoff-Derr, S., Göbel, P., Illing, P., Lieber, J., Schmidt, A., Wessel, L.M., Berthold, L.D., Hahn, G., Hirsch, W., Moritz, J.D., Schröder, C., Schumacher, R., Stegmann, J., Steinborn, M., Tietze, R., Wunsch, R., Deppe, W., Hermann, T., Kiosz, D., Leidig, E., Mayer, H., Oepen, J., Stachow, R., Ahrens, F., Frey, G., Huttegger, I., Preil, M.-L., Schmittenbecher, P.P., Traupe, H., Eberhardt, O., Hasler, C., Krauspe, R., Meenen, N.M., Meurer, A., Rödl, R., Stücker, R., and Zilkens, C.
- Published
- 2015
- Full Text
- View/download PDF
6. Modifizierende Gene bei der zystischen Fibrose.
- Author
-
Knauer, N., Ratjen, F., and Grasemann, H.
- Published
- 2005
- Full Text
- View/download PDF
7. Empfehlungen zur Diagnostik, Therapie und Pr�vention von Pneumonien bei erworbenem Immundefizit.
- Author
-
Dalhoff, K., Ewig, S., H�ffken, G., Lorenz, J., Maass, M., Niedermeyer, J., Ratjen, F., Welte, T., and Wilkens, H.
- Published
- 2002
- Full Text
- View/download PDF
8. Besonderheiten im pulmonalen NO-Stoffwechsel bei Patienten mit zystischer Fibrose.
- Author
-
Grasemann, H. and Ratjen, F.
- Published
- 2002
- Full Text
- View/download PDF
9. Diabetes mellitus bei zystischer Fibrose.
- Author
-
Ratjen, F. and Konietzko, N.
- Published
- 2004
- Full Text
- View/download PDF
10. [Cystic fibrosis modifying genes].
- Author
-
Knauer N, Ratjen F, and Grasemann H
- Subjects
- Cystic Fibrosis Transmembrane Conductance Regulator genetics, Humans, Mutation, Cystic Fibrosis genetics
- Abstract
Cystic fibrosis is a common autosomal recessive disease that is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The CFTR gene encodes a membrane-bound chloride ion channel. CFTR gene mutations cause alterations in fluid and salt secretion of various tissues. The CF phenotype is highly variable even in siblings and twins carrying the same CFTR mutations. The course of CF pulmonary disease is modulated by both environmental and genetic factors independent of CFTR. This review summarises association studies that focused on disease modifier genes in CF. Understanding the molecular and cellular basis of the genotype-phenotype associations will help to better understand the disease and to identify new targets for therapeutic interventions in CF.
- Published
- 2005
- Full Text
- View/download PDF
11. [Diabetes mellitus in cystic fibrosis].
- Author
-
Ratjen F and Konietzko N
- Subjects
- Diabetes Mellitus diagnosis, Humans, Cystic Fibrosis complications, Diabetes Mellitus epidemiology
- Published
- 2004
- Full Text
- View/download PDF
12. [Recommendations for the diagnosis, therapy and prevention of pneumonia in the immunocompromised host].
- Author
-
Dalhoff K, Ewig S, Höffken G, Lorenz J, Maass M, Niedermeyer J, Ratjen F, Welte T, and Wilkens H
- Subjects
- Germany, Humans, Immunocompromised Host, Incidence, Pneumonia epidemiology, Pneumonia prevention & control, Pneumonia therapy, Quality Assurance, Health Care, Immunologic Deficiency Syndromes complications, Pneumonia diagnosis
- Published
- 2002
- Full Text
- View/download PDF
13. [Pulmonary metabolism of nitric oxide (NO) in patients with cystic fibrosis].
- Author
-
Grasemann H and Ratjen F
- Subjects
- Cystic Fibrosis Transmembrane Conductance Regulator genetics, Humans, Reference Values, Cystic Fibrosis metabolism, Lung metabolism, Nitric Oxide metabolism
- Abstract
Airway nitric oxide (NO) and its metabolites are involved in a number of physiological and pathophysiological processes. For instance, NO relaxes airway smooth muscle, improves airway ciliary motility, has antimicrobial effects, and increases expression of the CFTR (cystic fibrosis transmembrane regulator) protein in airway epithelial cells. Of interest, concentrations of NO and of bioactive S-nitrosothiols (SNOs) are decreased in the airways of patients with cystic fibrosis (CF). When compared to patients with relatively normal pulmonary NO formation, CF patients with low NO-concentrations have a significantly reduced pulmonary function and a higher frequency of bacterial colonisation of the airways with pathogens such as P. aeruginosa. As a consequence of these observations clinical trails have now been initiated to study possible effects of an augmented bronchial NO-concentration in CF-patients.
- Published
- 2002
- Full Text
- View/download PDF
14. [Bronchoalveolar lavage in childhood: technical aspects and reference values].
- Author
-
Ratjen F and Costabel U
- Subjects
- Adolescent, Adult, Child, Child, Preschool, Diagnosis, Differential, Female, Humans, Lung Diseases immunology, Male, Reference Values, Sensitivity and Specificity, Bronchoalveolar Lavage Fluid immunology, Lung Diseases diagnosis
- Abstract
(BAL) has been increasingly used in recent years also in children. In paediatric pulmonary diseases, however, interpretation has proved difficult in the absence of standard reference values for BAL in childhood. It is the purpose of the present publication to discuss the methodological aspects of BAL in childhood and to proviced criteria by means of standard reference values for the assessment of BAL in paediatric patients. In a group of 50 children aged 3 to 15 years with healthy lungs, who were subjected to BAL during an elective surgical intervention, we examined both cellular and non-cellular components of the BAL. Whereas the percentage of macrophages and lymphocytes in the total population did not differ significantly from the standard values in adults, the absolute and relative granulocyte count was found to be elevated in children under 8 years of age. The CD4/CD8 quotient of BAL was 0.7 on the average, and hence clearly below the standard reference values defined for adults. In the non-cellular components we found an increase in the level of all proteins from plasma, whereas locally produced proteins did not differ from the findings in healthy adults. The total phospholipid content of BAL was markedly enhanced in children below 8 years of age and decreased with increasing age. These differences between children and adults should be taken into account when interpreting pathological findings. They are the basis for better defining the ranking of BAL in paediatric pulmonary diseases.
- Published
- 1997
15. [The importance of lung function as a predictor of 2-year mortality in mucoviscidosis].
- Author
-
Grasemann H, Wiesemann HG, and Ratjen F
- Subjects
- Adolescent, Adult, Child, Child, Preschool, Cystic Fibrosis physiopathology, Female, Forced Expiratory Volume physiology, Humans, Lung Diseases, Obstructive physiopathology, Male, Prognosis, Pulmonary Gas Exchange physiology, Survival Rate, Cystic Fibrosis mortality, Lung Diseases, Obstructive mortality, Lung Volume Measurements
- Abstract
Prediction of mortality in cystic fibrosis (CF) has become an important issue in the era of lung transplantation. A study from Toronto has shown a forced expiratory volume in one second (FEV1) below 30% predicted to be the best predictor of two-year mortality. The purpose of this investigation was to assess whether these data are relevant for other CF centers with a different overall life expectancy. We have analysed pulmonary function tests (PFTs) obtained in our population of CF patients between 1979 and 1991. 19 of the 73 patients included in this analysis had died. Cox proportional hazard regression analysis was performed using the lung function parameters as single covariates. In addition results of PFTs obtained two years before death were compared to similarly lagged values of surviving patients. Inspiratory vital capacity (IVC) (p < 0.0001), the ratio of residual volume/total lung capacity (RV/TLC) (p < 0.0001), forced expiratory volume in one second (FEV1) (p < 0.0002), specific conductance (sGaw) (p < 0.025) and a weight for height below the third percentile (p < 0.023) were significant predictors of two-year mortality. Two-year mortality were 50% for a FEV1 < 30% predicted and 47% for a RV/TLC ratio > 50%. Our data confirm that a FEV1 < 30% and a RV/TLC ratio > 50% are significant predictors of mortality in CF. However, interindividual variability in survival with a FEV1 < 30% is high. The decision for lung transplantation can therefore not be based on pulmonary function alone.
- Published
- 1995
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.