Search

Copyright of Der Urologe A is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Background: Therapy of epitheloid angiomyolipomas (eAML) may be challenging, since unlike classical angiomyolipomas this rare subclass of benign mesenchymal angiomyolipomas may present with lymph node metastases, local recurrent disease, and/or systemic metastatic disease in up to 30% of cases., Objectives: We report here for the first time in Germany a case of eAML after successful treatment of malignant melanoma., Materials and Methods: Clinical and histological findings as well as results of the genetic analysis of the angiomyolipoma are presented., Results: A somatic, truncating mutation of the TSC2 gene was found in the angiomyolipoma., Conclusion: The relationship to histologically similar tumor entities are presented and therapeutic options based on the genetic classification are discussed., (© 2021. The Author(s).)