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The pre-operative myelograms performed using Dimer-X (dimeglumine-iocarmate) of 219 patients were re-evaluated post-operatively without knowledge of the operative findings. In 77% the myelographic interpretation was in agreement with the surgical diagnosis. The interpretation was difficult and unreliable when only one or few radiographic signs were present. In order to achieve optimal benefit from the investigation the history and clinical findings should also be considered as equally important. Myelography is only justified in clinically unclear cases. In view of this and possible complications a stringent indication in necessary.