1. [The effectiveness of the new fluoroquinolones against the normal bacterial flora of the conjunctiva].
- Author
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Koss MJ, Eder M, Blumenkranz MS, Klauss V, Ta CN, and de Kaspar HM
- Subjects
- Aged, Anti-Bacterial Agents administration & dosage, Cell Survival drug effects, Female, Humans, Male, Staphylococcus cytology, Streptococcus cytology, Conjunctiva drug effects, Conjunctiva microbiology, Conjunctivitis, Bacterial drug therapy, Conjunctivitis, Bacterial microbiology, Fluoroquinolones administration & dosage, Staphylococcus drug effects, Streptococcus drug effects
- Abstract
Background: Our aim was to determine the antibiotic susceptibility of the preoperative conjunctival bacterial flora against 25 commonly used antibiotics, especially the new fluoroquinolones levofloxacin, gatifloxacin, and moxifloxacin., Patients and Methods: The Kirby-Bauer disk-diffusion technique was used to test for the in vitro antibiotic susceptibility of conjunctival bacterial strains isolated from 160 patients (median=74 years, mean=71 years) undergoing cataract surgery at the Department of Ophthalmology, Stanford University, CA, USA., Results: Among the 256 bacteria isolated, 201 (79%) were coagulase-negative staphylococci (CNS), 26 Staphylococcus aureus, 15 Streptococcus group D and 14 gram-negative rods. A total of 100 of these 256 strains (39%) were classified as multiresitant (resistant to>or=five antibiotics). The resistance rate (RR) of commonly used antibiotics for all CNS was: gatifloxacin=moxifloxacin
- Published
- 2007
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