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Introduzione alla sezione che raccoglie gli atti del convegno internazionale “Effetto Canone. La forma ‘Antologia’ nella letteratura italiana contemporanea”, tenutosi presso l’Università IULM di Milano il 13 giugno 2016, in collaborazione con l’Università KU Leuven e organizzato da Paolo Giovannetti e Carmen Van den Bergh.

The concentration of oxygen and its rate of consumption are important factors in certain medical treatments, such as radiotherapy and photodynamic therapy (PDT). Measuring the tissue concentration of oxygen or its partial pressure (pO2) can be achieved by taking advantage of the oxygen-dependent luminescence lifetime of certain molecules, including metallo-porphyrin derivatives, due to the oxygen-dependent quenching of their triplet state. Unfortunately, most of these porphyrin derivatives are phototoxic due to the O21? produced in the pO2 measurement procedure. The aim of this work was to characterize new nanoparticle oxygen sensors, where the palladium-porhyrin molecule (Pd-meso-tetra(4-carboxyphenyl)porphyrin) or its dendrimer form, is incorporated into an oxygen permeable matrix of chitosan-based colloidal particles. It was hypothesized that the reactive O21? produced during the pO2 measurement would react inside the particle thus reducing its toxicity for the surrounding tissue, whereas the 3? ground state of O2, that is to be measured, would diffuse freely in the peptide. We observed that the incorporation of the porphyrin in the nanoparticles resulted in a reduction of the phosphorescence lifetime sensitivity to pO2 by about one order of magnitude. Our studies of these new sensors indicate that the oxygen concentration can be measured in aqueous solutions with a precision of ±20% for oxygen concentrations ranging between 0% and 25%.

The LIDAR (LIght Detection And Ranging) technique has developed into one of the practical high performance techniques for conducting air quality and meteorological measurements. DIfferential Absorption Lidar (DIAL) is used for measuring trace gases, including pollutants like ozone at low concentrations. Multiple wavelengths backscatter and depolarization measurements give information about particles in the atmosphere, and single wavelength lidar can be used for meteorological measurements like wind velocity and temperature. Range resolved in situ data obtained by lidar can play a significant role in our understanding of the air quality in the planetary boundary layer, particularly when applied in conjunction with air quality models. This is because DIAL can be used to measure concentrations in three dimensions in real time with a spatial resolution that corresponds well to that used in the model calculations. Thus one obtains an advantage when comparing with point measurements at or near ground level which are often perturbed by local emissions. A summary of the lidar principle is presented here, followed by different examples of vertical ozone profiles and time series obtained with a new optical layout of the EPFL-LPAS DIAL system using dual telescope detection. These data were obtained during the summer 96 field campaign in the Geneva area. Results are then compared with the mesoscale Eulerian model calculations performed in our laboratory. The overall results provide new insight into air pollution dynamics in the Geneva area and calculations are under way, using the model adjusted by the measurements, to optimize air pollution abatement strategies under certain atmospheric conditions in this part of Switzerland.

The significance, development, and different forms of educational plans and the special role of mentors and case managers in youth care in the Netherlands are presented.