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Aim of the Study: Case report on risk management for the epidemiology of an infectious disease threat scenario at the municipal level using the example of the Asian tiger mosquito (ATM) with communication of figures based on experience to stakeholders in the public health service METHODS: Formal and substantive presentation of a list of defined control measures together with site-specific modification and evaluation of efficacy RESULTS: Based on a timely education campaign, establishment of a population of ATM first observed in the fall of 2016 could be prevented at the local level. With favourable low temperatures during the 2016/2017 winter months, primarily physical control methods were effective. In the spring of 2017, ATM was no longer detected by a total of 4 monitoring units, each with a suction trap and 3 passive traps. In the following period, up to and including the spring of 2019, no invasive species of mosquito were identified in the cemetery originally involved or in the adjacent residential areas or recreational grounds Overall, cooperation among external experts and stakeholders from the public health service at the level of individualised medicine were able to prevent an insect-borne infection of the local population; a gradual approach following defined criteria for insect control proved to be effective and efficient., Conclusion: The occurrence of the ATM is primarily a local event that requires a differentiated weighing-up between a specific and abstract hazard potential by the regional health authorities. In addition to an objective and prompt education campaign for the population involved as a trust-building action, primary physical control measures in terms of barrier measures are effective; if necessary, chemical and biological controls can be used as complementary measures., Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)

Background: The International Health Regulations (IHR) 2005 were conformed to German law on July 20, 2007 and described in detail by the Implementing Act (IHR DG). According to these legal bases, "designated airports" must maintain special capacities for protection against health threats, and are also responsible for performing regular IHR exercises., Objectives: Representation of the optimization of established operational concepts of various professions to manage infectious biological threats without obstruction of international travel, and mediation of experience to IHR professionals., Materials and Methods: An exercise based on the case scenario of a travel-related febrile illness was performed at Munich International Airport on November 11, 2013. Preparations took 6 months and the exercise itself lasted nearly 12 h. The follow-up lasted an additional 9 months. A qualitative and quantitative evaluation of the exercise was completed., Results: From an Individual Medicine and Public Health perspective, modular work structures and risk communication functioned adequately. The medical examination of passengers was also well managed. Areas requiring further optimization included arrival/departure times of external actors, transport of the index patient to hospital and protective measures for individual participants. Overall, a defined biological threat scenario representing a double infection with two highly pathogenic germs was handled satisfactorily without affecting international air travel., Conclusions: Modular supply components are an effective and forward-looking means in protection against threats occurring at airports. Key success factors include sufficient staff mobility, immediate self-protection of actors involved, effective risk communication and a strong overall coordination and monitoring of the situation.

The coherence between prae- and posttherapeutical TNM findings had been checked up in a multicentrically registered patient material of 2,481 non-praetreated plate epithelium carcinomas of the lips and oral mucosa. Whereas the extension of the tumour has in the main been the same, the findings on lymph nodes had a trend showing essential deviations. In a two-dimensional examination of 851 histologically prepared preparations of lymph nodes, a prognostic relevance acc. to metastases had been registered for the characteristics palpation finding of the lymph node, tumour extension, tumour infiltration. Multidimensional analyses have to be realized.

In a retrospective multicenter study the role of multiple cancer has been assessed in 2481 patients with carcinomas of the lips and oral cavity. In 3.2% of the cases the malignancies developed outside the maxillofacial area. In the majority of cases two malignant neoplasms were found. Most of them were histologically carcinomas. The bronchi and stomach were common localizations in patients with lip carcinomas, whereas patients with oral carcinomas exhibited mainly cancers of the breast, stomach and uterus. Sex-limited multiple cancers associated with oral carcinoma occurred predominantly in women. Surgery is the most common form of treatment. The prognosis for patients with lip carcinomas is significantly poorer when multiple cancers are present.