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The pancreas develops from ventral and the dorsal buds, which undergo fusion. Failure to fuse results in pancreas divisum, which is defined by separate pancreatic ductal systems draining into the duodenum. Risk of developing pancreatitis is increased in pancreas divisum because of insufficient drainage. MR cholangiopancreatography (MRCP) is the technique of choice for detecting pancreas divisum non-invasively. Annular pancreas is the result of incomplete rotation of the pancreatic bud around the duodenum with the persistence of parenchyma or a fibrous band encircling (and sometimes stenosing) the duodenum. Acute pancreatitis is usually caused by bile duct stones or alcohol abuse. The Atlanta classification differentiates between mild acute and severe acute pancreatitis associated with organ failure and/or local complications such as necrosis, abscess or pseudocyst. Contrast-enhanced multi-detector row CT is the method of choice to assess the extent of disease. Balthazar et al.'s CT severity index assesses the risk of mortality and morbidity. In acute pancreatitis, the role of MRCP is mainly limited to finding bile duct stones in patients with suspected biliary pancreatitis. Chronic pancreatitis results in relentless and irreversible loss of exocrine (and sometimes endocrine) function of the pancreas. MDCT even shows subtle calcifications. MRCP is the method of choice for non-invasive assessment of the duct. Inflammatory pseudotumor in chronic pancreatitis and groove pancreatitis are difficult to differentiate from pancreatic cancer. In these cases, multiple imaging methods such as MDCT, MRI and endosonography including biopsy may be used to make a diagnosis.

This is a retrospective analysis of the treatment of 18 patients with pancreatic injuries at our institution. 13 were victims of blunt abdominal trauma. 17 sustained a polytrauma and had an ISS > 15. They had 2.4 associated intraabdominal and 2.7 associated extraabdominal injuries. The mean pancreatic organ injury scale was II. A partial duodenopancreatectomy was performed in one case. In 5 cases a distal pancreatic resection was necessary. In the remaining patients drainage procedures were applied. 3 additional injured organs had to be treated during the first operation. 2 of them were situated intraabdominally. The primary operative procedure was performed in 13 cases during the first 6 hours after the trauma. 7 patients (39 %) died during the hospitalisation. None deceased during an operation. 5 patients (28 %) died because of abdominal complications. 4 of 5 patients with injuries to the great vessels died. 12 had abdominal complications. The mean hospitalisation time was 49 days. The mean drainage time was 26 days. The patients sustained parenteral nutrition for 21 days. The priority in the primary operative approach is damage control. This consists of bleeding control, control of enteral spillage, assessment of pancreatic damage, especially recognition of any ductal injury and generous drainage of the injured pancreas. Definitive treatment in the severly injured patient has to be performed after hemodynamic stabilisation without delay by an experienced surgeon.

Purpose: To document our experience with spiral hydro-CT of the pancreas based on a combination of pharmacologic intestinal paralysis and water distension of the stomach and duodenum with specific reference to tumor detection rate, differentiation of malignant versus benign tumors and assessment of tumor resectability in a prospective study on 211 consecutive patients. Material and methods: Between May 1994 und September 1997, 211 patients with suspect of pancreatic neoplasm from clinical, laboratory or other imaging data were examined. Our Hydro-CT techniques were based on intravenous injection of 40 mg N-butylscopolaminiumbromid (Buscopan) for intestinal paralysis, gastric and duodenal wall distension by oral administration of an average of 1.5 l warm tap water, 30 ° RAO patient's positioning, individualized contrast injection technique using portal vein enhancement as reference and thin slice spiral CT (3 mm slice thickness, 6 mm table feed and 3 mm secondary reconstruction). Examined parameters were: (1) tumor detection rate, (2) differentiation of malignant versus benign disease, (3) differential diagnosis and (4) accuracy of assessment of resectability by identification of infiltration into adjacent organs and vessel structures relevant for resectability such as splenic, superior mesenteric, portal vein and celiac trunk, superior mesenteric, splenic and hepatic arteries. As gold standard for positive tumor detection and description surgery (of potentially resectable tumors) and microscopic diagnosis (of clearly unresectable tumors) were used and for negative tumor detection an event-free survival of six months, respectively. Results: 96 % of the examinations were well tolerated. In only 4 % was on-site administration of a gastric tube required because of vomiting. In 2 % of the patients a slight allergic reaction to the contrast medium was seen. The prevalence of a pancreatic neoplasm was 37,8 %. In tumor detection Hydro-CT reached an overall accuracy of 94,8 % with a sensitivity of 93,7 % and a specificity of 95,2 %. 52 patients underwent surgical exploration 34 of whom with tumorfree resection margins (R0 resection) corresponding to a resection of 42,5 %. In those assessment of resectability reached an overall accuracy of 94,6 % with a sensitivity of 91,2 % and specificity of 95,6 %. Conclusion: The new technique of Hydro-CT based on thin slice and spiral methodology including pharmacologic intestinal paralysis and water distension results in a high tumor detection rate and reliable assessment of resectability.