1. Gezielte Zellsortierung in der Einzelzellgenomik
- Author
-
Anne-Kristin Kaster and Morgan S. Sobol
- Subjects
Life sciences ,biology ,Rare biosphere ,Context (language use) ,Genomics ,Computational biology ,Cell sorting ,Biology ,Genome ,Human genetics ,Metagenomics ,ddc:570 ,Molecular Biology ,Selection (genetic algorithm) ,Biotechnology - Abstract
Single cell genomics (SCG) can provide reliable context for assembled genome fragments on the level of individual prokaryotic genomes and has rapidly emerged as an essential complement to cultivation-based and metagenomics research approaches. Targeted cell sorting approaches, which enable the selection of specific taxa by fluorescent labeling, compatible with subsequent single cell genomics offers an opportunity to access genetic information from rare biosphere members which would have otherwise stayed hidden as microbial dark matter.
- Published
- 2021