Search

The number of the different neuropeptides-containing nerve fibres and immunocompetent cells was changed in diabetes mellitus (DM) in different organs. In this work we investigated the effect of DM on quantitation of the nerve fibres using immunhistochemistry. After two weeks of the DM the quantitiy of the different nerve fibres increased significantly both in the mucous membrane and glands of the tongue. The number of the immunocompetent cells (lymphocytes, plasma cells, mast cells) increased as well significantly. Some of these cells showed also immunoreactivity for substance P and neuropeptide Y. A few substance P cells were in very close relation to the SP immunoreactive nerve fibres. After four weeks of DM the number of the nerve fibres was decreased compared to the 2 weeks treatment, however, the number of them was higher compared to the control. The close correlation between the nerve fibres and immune cells might play a crucial role in maintaining the homeostasis in the mucous membrane and glands of the tongue as well as in the increasing inflammation and elimination of it.

The silicon based impression materials are often used in dental practice. Recently, we have observed two cases of contact allergic reaction after using Silodent (Ferrokémia) impression material. Epicutaneous test has shown that the allergic reaction is provoked by the catalisator. This hypersensitivity reaction is due to a previous sensibilization (e.g. previous impression taking or environmental hazards). No epicutaneous reaction to the other types of silicon based impression materials was found.

The blood group and the blood plasma protein properties can, by means of special methods, be proved also in saliva, in the mouth soft tissue, in the teeth, in the dental deposit and in the dental socket extension. These--among other things--are of great importance in the judical dental practice.