1. [Blood myoglobin in children with progressive muscular dystrophy and in carriers].
- Author
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Calandi C, Baretti S, Pacciani G, Bagni P, Borsotti M, Tozzi P, and Adami Lami C
- Subjects
- Adolescent, Adult, Carrier State enzymology, Child, Child, Preschool, Creatine Kinase metabolism, Female, Humans, Isoenzymes, Male, Middle Aged, Muscular Dystrophies enzymology, Carrier State blood, Muscular Dystrophies blood, Myoglobin blood
- Abstract
We studied the behaviour of serum myoglobin in 32 children affected by Duchenne muscular dystrophy, in 30 mothers (10 definite carriers and 20 possible carriers), in 5 sisters (possible carriers) and in 40 healthy women (control). The serum myoglobin was always increased in the patients affected by Duchenne muscular dystrophy; the greatest values were in the patients who were still ambulant, with a behaviour similar to creatine kinase. In the carriers the myoglobinemia showed a significant increase in definite carriers, while there was no significant difference between the possible carriers and the controls.
- Published
- 1984