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Glycoprotein IIb/IIIa inhibitors have been recently proposed as a bridge to rescue transluminal coronary angioplasty in ST elevation myocardial infarction patients in whom thrombolysis fails; but data in its feasibility, safety and efficacy are still limited. In 47 consecutive acute myocardial infarction patients in whom thrombolysis failed to achieve 90 minute reperfusion, tirofiban was given at full regimen. Our results have been compared with those obtained in a control group of 48 consecutive acute myocardial infarction patients admitted two years before, period in which tirofiban and rescue angioplasty were not available in our hospital. Our preliminary data suggest this approach is feasible and safe, with possible clinical benefit in this high-risk subgroup of patients.

Background: The aim of this study was to achieve left ventricular resynchronization by means of right ventricular pacing., Methods: We studied 12 patients (9 males, 3 females, mean age 61.7 +/- 19.5 years), with syncope, II degree atrioventricular block or ventricular arrhythmias, without intraventricular conduction disturbances. Single and dual site pacing, synchrony or at different delay, was made in the right ventricular, outflow tract from the apex, and midseptal areas., Results: In all patients we obtained the shortest QRS duration with synchrony or delayed bisite pacing (standard ventricular apex pacing 170 +/- 20 ms; bisite pacing 137 +/- 13 ms)., Conclusions: Our data demonstrate that appropriate right ventricular pacing can lead to left ventricular resynchronization.