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To investigate the relationship between air pollution and histologic type of lung cancer we conducted a case-control study among deceased men in Trieste, Italy. 755 cases of lung cancer and 755 controls were identified through the local autopsy registry. Information on smoking habits, occupation and place of residence was obtained from the subject's next-of-kin. Air pollution at the residence of each subject was estimated from the average value of total particulate at the nearest monitoring station. Spatial models and logistic regression were used to evaluate the effect of residence and air pollution on LC after adjustment for age, smoking habits, likelihood of exposure to occupational carcinogens and social group. The risk of lung cancer increased with increasing level of air pollution for all types of lung cancer combined (P = 0.022), for small cell carcinoma (P = 0.016) and for large cell carcinoma (P = 0.049). Compared with inhabitants of the residential area, residents of the rural area had a relative risk (RR) of 0.6 (95% confidence interval (CI): 0.4-1.0). The RR was 1.5 (1.0-2.2) for residents of the center of the city and 1.4 (1.0-2.1) for residents of the industrial area. In the center of the city the excess risk was almost completely restricted to small cell carcinoma (RR = 2.0) and to large cell carcinoma (RR = 2.6). In the industrial area the risk was increased especially for adenocarcinoma (RR = 2.1). These results provide evidence that air pollution is a moderate risk factor for certain histologic types of lung cancer.

Recent data collected by the Japanese government confirm that our society is destined to become a high elderly dominated society. Forecasts show that by 2010 approximately 21% of the population in countries such as France, USA and Japan will be over 65 years old. It is therefore becoming increasingly urgent to solve the problem of integration for the elderly and disable within the socioeconomic structure. The authors tackle the question of how service robots may be applied to resolve this problem. This paper presents a rapid overview of the most recent applications of robotics to the field of services for the elderly and disabled, paying particular attention to research carried out at the Laboratory of Robotics, Department of Mechanics of Milan Politecnico by Prof. S. Rovetta.

Expert systems are application tools based on logic and containing a wide knowledge in a specific field; their aim is the simulation of an expert's behavior in reasoning and making decisions inherent a small cultural domain. Applications in medicine and radiology are numerous and constantly increasing. The possibility of their use in the application of diagnostic and staging protocols seems particularly interesting. The development and commercial availability of expert systems programming tools (called shells) make it certainly easier to develop consultations systems, even to non-experienced users. The purpose of this research is the definition and description of the stages encountered during the development of an expert system for diagnosis, staging and treatment of bladder cancer using self-developed shell, designed for radiological use, called Experto. The steps of knowledge collection, definition of diagnostic and therapeutic protocols and system development are described. The consultation system assessed the correct TNM stage of the 27 examined cases.

Research on the medical applications of artificial intelligence has increased the knowledge of logical and methodological principles of clinical reasoning. Thus, computer-based diagnostic systems are developed on the basis of progress in this field, because thorough knowledge is necessary to obtain efficient simulation. This work was aimed at analyzing the structure of medical and radiological reasoning and at discussing the modalities to simulate it with computer-based diagnostic systems. The diagnostic process includes two steps: data collection and data interpretation; radiological reasoning involves the following 5 steps: procedural, executive, observative, interpretative and communicative. Each of them needs a different approach to simulation, considering, in its development, the different characteristics of each kind of reasoning. The expert system shells on the market are necessary tools to develop expert systems, but they cannot cover the whole of processes taking place during radiological work. Therefore, a particular, radiology-aimed shell should be developed to help the radiologist.

Laparoscopic cholecystectomy can be performed following two main approaches: the french technique, used by the majority of surgeons, and the anglo-saxon technique. The Authors describe the basic concept of the "left side" approach according to the Anglo-american method, underlining some of the advantages. Their one-year results (November 1990-November 1991) confirm the data already available in the Literature.

The data to be discussed in this paper are drawn from a study of three groups of infants: small (low birth weight less than 10 centile for gestational age), preterm (gestational age less than 37 weeks) and full term. The total population of this study consisted of 12 children (4 subjects for each group). The purpose of the study was to examine phonetic and lexical development in these three populations to determine both normal and delayed patterns of this development over the second year of life. The time sampled for early behaviors were 18, 19, 20, and 21 months, based on chronological age. The spontaneous verbal productions of the subjects were tape-recorded and transcribed using phonetic symbols (IPA). Comparison were made between preterm and full term infants based on both chronological and gestational age. The data resulting from the comparison of our subjects on these parameters provide us with evidence that there can be early indicators of later speech and lexical development of the group of preterm infants

The palpebral region is one of the commonest locations for basal cell epitheliomas of the face. The tumor can spread to both orbital cavity and its structures. Ten patients with basal cell epitheliomas of the face were studied with US to investigate its diagnostic accuracy; US findings were compared with CT ones. In all cases US allowed a complete study of both morphology and structure of the tumor; it precisely defined the status of the superficial structures of the orbital cavity (cornea and anterior chamber of the eye), differentiating between tumor contiguity, compression and infiltration. US seems therefore essential to the preoperative assessment of tumor spread and during the follow-up of patients with palpebral basaliomas.