Search

The authors present a clinical survey conducted to value the antiseptic and reparative properties of collagenasis (clostridiopeptidiasi A), in the topical treatment of skin lesions. The study presented 90 patients with burns, pressure sores, abrasions and trophic ulcers. The results obtained were highly positive in terms of the healing or cleansing of the wound, bearing further witness to the reliability of the product in question.

The therapeutic effectiveness and the tolerability of a collagenase-chloramphenicol ointment were studied on a group of 20 patients (mean age 73.4 +/- 13.6 years, range 25-88 years) with lower limb ulcerations of various origin. The ointment proved capable of favourably influencing the debridment and the healing process of these lesions. Statistically significant improvements were observed after days of treatment for debridment, inflammation and granulation, after eight days for the lesion size and after ten days for epithelization. Tolerability was very good.